Technology gives many oppurtunites for cattle farmers for easier and effective herd management possibilities. New era provides many realistic applications using smart applications for farmers. Especially milking is ve...Technology gives many oppurtunites for cattle farmers for easier and effective herd management possibilities. New era provides many realistic applications using smart applications for farmers. Especially milking is very popular for engineering applications. Reproductive technologies can be seen as frontier applications. Reproductive performances of the dairy farms can be defined as number of calves for cows in a year. It means new material for meat and milk production. Because new female calf means new cow for her while male calf means new material for beef. If meat and milk production are to be increased, cow productivity, i.e. the number of calves produced lifetime must be improved and increased. Although varying among herds, annual average herd incidences of reproductive disorders and reproductive performance were similar to those reported. Managerial practices influenced incidences of retained placenta and uterine infection, days open of cows not bred and of all cows, services per conception and percentages of herd open more than 100 days and culled for low production. Good heat detection programs can have a major impact on overall herd reproductive performance. The best heat detection programs start with careful timing, good observation and the effective use of detection aids. Being able to distinguish and interpret cow behaviour and other signs is critical, so are good record keeping and training for the people responsible for heat detection. Generaly, farmers with the best heat detection results use a combination of observation and heat detection aids. Several options are available to aid heat detection and increase heat detection rates. Although a rich variety of methods have been introduced for the detection of oestrus, a more accurate and practical method is still required.展开更多
In a total of 83 UN specimens were investigated for proto-oncogene mutations, tumor supressor genes promoter methylation status and c-myc and Ki-67 expression. Point mutations in c-myc were detected in cases with high...In a total of 83 UN specimens were investigated for proto-oncogene mutations, tumor supressor genes promoter methylation status and c-myc and Ki-67 expression. Point mutations in c-myc were detected in cases with high grade and proliferation index. Mutated K-ras proto-onco- gene profiles were detected in 17 (21%) tumoral spiecemens that examined. Tumor specimens were also showed hypermethylated promoter domain for the SFRP2, MGMT tumor supressor genes. These findings showed the combine effect of mutated c-myc and K-ras oncogene and epigenetic inactivation of tissue specific tumor supressor genes (TS) play a crucial role in tumor progression and recurrence in UN carcinogenesis.展开更多
文摘Technology gives many oppurtunites for cattle farmers for easier and effective herd management possibilities. New era provides many realistic applications using smart applications for farmers. Especially milking is very popular for engineering applications. Reproductive technologies can be seen as frontier applications. Reproductive performances of the dairy farms can be defined as number of calves for cows in a year. It means new material for meat and milk production. Because new female calf means new cow for her while male calf means new material for beef. If meat and milk production are to be increased, cow productivity, i.e. the number of calves produced lifetime must be improved and increased. Although varying among herds, annual average herd incidences of reproductive disorders and reproductive performance were similar to those reported. Managerial practices influenced incidences of retained placenta and uterine infection, days open of cows not bred and of all cows, services per conception and percentages of herd open more than 100 days and culled for low production. Good heat detection programs can have a major impact on overall herd reproductive performance. The best heat detection programs start with careful timing, good observation and the effective use of detection aids. Being able to distinguish and interpret cow behaviour and other signs is critical, so are good record keeping and training for the people responsible for heat detection. Generaly, farmers with the best heat detection results use a combination of observation and heat detection aids. Several options are available to aid heat detection and increase heat detection rates. Although a rich variety of methods have been introduced for the detection of oestrus, a more accurate and practical method is still required.
文摘In a total of 83 UN specimens were investigated for proto-oncogene mutations, tumor supressor genes promoter methylation status and c-myc and Ki-67 expression. Point mutations in c-myc were detected in cases with high grade and proliferation index. Mutated K-ras proto-onco- gene profiles were detected in 17 (21%) tumoral spiecemens that examined. Tumor specimens were also showed hypermethylated promoter domain for the SFRP2, MGMT tumor supressor genes. These findings showed the combine effect of mutated c-myc and K-ras oncogene and epigenetic inactivation of tissue specific tumor supressor genes (TS) play a crucial role in tumor progression and recurrence in UN carcinogenesis.