1 Introduction Voluminous Mesozoic magmatic rocks containing abundant Au-Mo polymetallic mineralization resources are developed in the Xiaoqinling-Xiong’ershan district of the southern margin of the North China Crato...1 Introduction Voluminous Mesozoic magmatic rocks containing abundant Au-Mo polymetallic mineralization resources are developed in the Xiaoqinling-Xiong’ershan district of the southern margin of the North China Craton(NCC).展开更多
The high-speed motorized spindle, as the key component of machining centers and other high-end CNC machine tools, has performance directly affecting machining accuracy. According to the internal motor character- istic...The high-speed motorized spindle, as the key component of machining centers and other high-end CNC machine tools, has performance directly affecting machining accuracy. According to the internal motor character- istics of the high speed motorized spindle in the paper, two major heat sources are analyzed and quantity of heat is calculated. The finite element analysis model of motorized spindle thermal characteristics is built through ap- plying the ANSYS Workbench. The thermal steady state, heat-structure coupling characteristics is carried out based on the cooling coefficient of thermal boundary conditions, and taking heating value of the bearing and mo- tor as thermal load, the temperature field distribution and thermal deformation of the spindle system are obtained, which prepare fox＂ the next thermal error modeling展开更多
背景:股骨头坏死出现新月征是病情进程的“分水岭”,修复和稳定骨-软骨界面对阻止病情继续进展和预防股骨头塌陷尤为重要。利用组织工程学同步修复、整合骨-软骨界面具有潜在优势。目的:综述探讨解决股骨头坏死软骨下分离的潜在适宜技...背景:股骨头坏死出现新月征是病情进程的“分水岭”,修复和稳定骨-软骨界面对阻止病情继续进展和预防股骨头塌陷尤为重要。利用组织工程学同步修复、整合骨-软骨界面具有潜在优势。目的:综述探讨解决股骨头坏死软骨下分离的潜在适宜技术。方法:检索1970年1月至2023年4月PubMed、Web of Science及中国知网、万方数据库中发表的相关文献,英文检索词:“Femoral head necrosis,Avascular necrosis of femoral head,Osteonecrosis of femoral head”等,中文检索词:“股骨头坏死,软骨下骨,软骨,软骨与软骨下骨整合”等,最终纳入114篇文献进行综述分析。结果与结论:①结构缺陷、缺血缺氧环境、炎症因素和应力集中可能造成股骨头坏死软骨下分离现象,软骨下骨分离会造成塌陷进展,并且可能与保髋手术失败相关,利用组织工程支架实现支架与骨-软骨界面的整合是治疗股骨头坏死软骨下分离的潜在方法之一。②目前的文献研究表明,多相、梯度支架和复合材料在促进骨、软骨细胞黏附与增殖,骨软骨基质的沉积方面均有提升,有助于支架与骨-软骨界面的整合,对治疗股骨头坏死软骨下分离有参考价值。③通过对支架表面进行修饰可以提高与界面整合的效率,但有各自不同的优缺点,提供不同环境的支架能够诱导同种间充质干细胞差异分化,有助于不同界面之间的整合。④未来有望应用于股骨头坏死软骨下分离的支架应为复合材料,具有梯度化和差异化的仿生结构,通过表面修饰和干细胞加载促进骨-软骨界面与支架的整合以实现治疗目的,但仍需进一步研究验证,而支架的降解速率与修复进度同步和不同界面之间的稳定性是未来需要解决的主要问题。展开更多
基金supported by the NSFC (41373039)the DREAM project of MOST, China (2016YFC0600403)
文摘1 Introduction Voluminous Mesozoic magmatic rocks containing abundant Au-Mo polymetallic mineralization resources are developed in the Xiaoqinling-Xiong’ershan district of the southern margin of the North China Craton(NCC).
文摘The high-speed motorized spindle, as the key component of machining centers and other high-end CNC machine tools, has performance directly affecting machining accuracy. According to the internal motor character- istics of the high speed motorized spindle in the paper, two major heat sources are analyzed and quantity of heat is calculated. The finite element analysis model of motorized spindle thermal characteristics is built through ap- plying the ANSYS Workbench. The thermal steady state, heat-structure coupling characteristics is carried out based on the cooling coefficient of thermal boundary conditions, and taking heating value of the bearing and mo- tor as thermal load, the temperature field distribution and thermal deformation of the spindle system are obtained, which prepare fox＂ the next thermal error modeling
文摘背景:股骨头坏死出现新月征是病情进程的“分水岭”,修复和稳定骨-软骨界面对阻止病情继续进展和预防股骨头塌陷尤为重要。利用组织工程学同步修复、整合骨-软骨界面具有潜在优势。目的:综述探讨解决股骨头坏死软骨下分离的潜在适宜技术。方法:检索1970年1月至2023年4月PubMed、Web of Science及中国知网、万方数据库中发表的相关文献,英文检索词:“Femoral head necrosis,Avascular necrosis of femoral head,Osteonecrosis of femoral head”等,中文检索词:“股骨头坏死,软骨下骨,软骨,软骨与软骨下骨整合”等,最终纳入114篇文献进行综述分析。结果与结论:①结构缺陷、缺血缺氧环境、炎症因素和应力集中可能造成股骨头坏死软骨下分离现象,软骨下骨分离会造成塌陷进展,并且可能与保髋手术失败相关,利用组织工程支架实现支架与骨-软骨界面的整合是治疗股骨头坏死软骨下分离的潜在方法之一。②目前的文献研究表明,多相、梯度支架和复合材料在促进骨、软骨细胞黏附与增殖,骨软骨基质的沉积方面均有提升,有助于支架与骨-软骨界面的整合,对治疗股骨头坏死软骨下分离有参考价值。③通过对支架表面进行修饰可以提高与界面整合的效率,但有各自不同的优缺点,提供不同环境的支架能够诱导同种间充质干细胞差异分化,有助于不同界面之间的整合。④未来有望应用于股骨头坏死软骨下分离的支架应为复合材料,具有梯度化和差异化的仿生结构,通过表面修饰和干细胞加载促进骨-软骨界面与支架的整合以实现治疗目的,但仍需进一步研究验证,而支架的降解速率与修复进度同步和不同界面之间的稳定性是未来需要解决的主要问题。
