Ralstonia solanacearum, the causative agent of bacterial wilt, is a soil-borne pathogen that poses a widespread threat to plants in the Solanaceae family. To elucidate the mechanism by which limonene exerts its effect...Ralstonia solanacearum, the causative agent of bacterial wilt, is a soil-borne pathogen that poses a widespread threat to plants in the Solanaceae family. To elucidate the mechanism by which limonene exerts its effects on R. solanacearum, we first assessed the impact of limonene on the physiological indicators of the pathogen and subsequently analyzed its transcriptome and metabolome. Our findings indicate that limonene has a potent inhibitory effect on R. solanacearum, and it also suppresses the formation of the bacterial community biofilm. Limonene primarily regulates the terpene biosynthesis pathway in R. solanacearum, thereby potentially affecting signal transduction in the pathogen and disrupting its normal growth and development. These results significantly enhance our understanding of limonene’s response to the induction of bacterial wilt and provide a reference for further prevention and control of R. solanacearum.展开更多
The synthetic microbial community is a synthetic microbial system co-cultured with multiple species, which has the characteristics of clear composition and strong controllability. Compared with a single colony, it can...The synthetic microbial community is a synthetic microbial system co-cultured with multiple species, which has the characteristics of clear composition and strong controllability. Compared with a single colony, it can achieve more complex functions and adapt to the changing environment more easily, so as to meet a wide range of needs. In this paper, the contents and concepts of microbial community and synthetic microbial community are briefly introduced, the principles that should be followed in the construction of microbial community are expounded, the methods and mathematical models used in the construction of synthetic microbial community are introduced, and the applications of synthetic microbial community in various fields are summarized. Finally, the challenges in the research of synthetic microbial communities are briefly described.展开更多
Rhinoplasty in Asia is becoming increasingly widespread.When taking into consideration the anatomical differences between the features of Caucasian and Asian patients,it is unsurprising that knowledge gained from rese...Rhinoplasty in Asia is becoming increasingly widespread.When taking into consideration the anatomical differences between the features of Caucasian and Asian patients,it is unsurprising that knowledge gained from research on Caucasian rhinoplasty is not always applicable to Asian rhinoplasty.Furthermore,reviews aimed at describing the recent developments in Asian rhinoplasty are rare.This review aims to provide a comprehensive summary of the latest trends in rhinoplasty for Asians by classifying it into three parts:methods,materials,and three-dimensional techniques,hopefully providing surgeons with references to aid in conducting rhinoplasty on Asians.展开更多
文摘Ralstonia solanacearum, the causative agent of bacterial wilt, is a soil-borne pathogen that poses a widespread threat to plants in the Solanaceae family. To elucidate the mechanism by which limonene exerts its effects on R. solanacearum, we first assessed the impact of limonene on the physiological indicators of the pathogen and subsequently analyzed its transcriptome and metabolome. Our findings indicate that limonene has a potent inhibitory effect on R. solanacearum, and it also suppresses the formation of the bacterial community biofilm. Limonene primarily regulates the terpene biosynthesis pathway in R. solanacearum, thereby potentially affecting signal transduction in the pathogen and disrupting its normal growth and development. These results significantly enhance our understanding of limonene’s response to the induction of bacterial wilt and provide a reference for further prevention and control of R. solanacearum.
文摘The synthetic microbial community is a synthetic microbial system co-cultured with multiple species, which has the characteristics of clear composition and strong controllability. Compared with a single colony, it can achieve more complex functions and adapt to the changing environment more easily, so as to meet a wide range of needs. In this paper, the contents and concepts of microbial community and synthetic microbial community are briefly introduced, the principles that should be followed in the construction of microbial community are expounded, the methods and mathematical models used in the construction of synthetic microbial community are introduced, and the applications of synthetic microbial community in various fields are summarized. Finally, the challenges in the research of synthetic microbial communities are briefly described.
基金the Key Clinical Projects of Peking University Third Hospital(grant no.BYSYFY2021005).
文摘Rhinoplasty in Asia is becoming increasingly widespread.When taking into consideration the anatomical differences between the features of Caucasian and Asian patients,it is unsurprising that knowledge gained from research on Caucasian rhinoplasty is not always applicable to Asian rhinoplasty.Furthermore,reviews aimed at describing the recent developments in Asian rhinoplasty are rare.This review aims to provide a comprehensive summary of the latest trends in rhinoplasty for Asians by classifying it into three parts:methods,materials,and three-dimensional techniques,hopefully providing surgeons with references to aid in conducting rhinoplasty on Asians.
