Cervical spondylosis of vertebral artery type is one of the chief patterns of cervical spondylosis.It is often described as neck pain accompanied with radiating pain and neurologic symptoms,such as sudden dizziness,bl...Cervical spondylosis of vertebral artery type is one of the chief patterns of cervical spondylosis.It is often described as neck pain accompanied with radiating pain and neurologic symptoms,such as sudden dizziness,blurred vision,tinnitus,nausea,vomiting,memory loss,and sudden fainting.The incidence of cervical spondylosis increases and patients with cervical spondylosis become progressively younger.Acupuncture in the cervical spondylosis of vertebral artery type treatment has a local positive reaction“Liuhe point”,in order to dredge the local Qi and blood.More and more evidences into the effectiveness and safety of cervical spine acupuncture for cervical spondylosis,specific neck pain,cervical radiculopathy,etc.This article summarizes the recent literature on acupuncture and acupuncture combined with other therapies for cervical spondylosis of vertebral artery type treatment and provides a comprehensive review from the perspectives of acupuncture therapy,warm needle moxibustion therapy,electroacupuncture,and acupuncture combined with other therapies,in order to provide reference and reference for clinical treatment.展开更多
Objective:To examine the therapeutic effects of the Traditional Chinese Medicine Qushi Kaiyu decoction on Non-alcoholic fatty liver disease(NAFLD)rats and relevant mechanisms.Methods:A NAFLD rat model was constructed ...Objective:To examine the therapeutic effects of the Traditional Chinese Medicine Qushi Kaiyu decoction on Non-alcoholic fatty liver disease(NAFLD)rats and relevant mechanisms.Methods:A NAFLD rat model was constructed in this study using a high-fat diet,and different Qushi Kaiyu decoction doses were administered by gavage.The body weight,liver index,and blood lipid biochemical markers(TG,Total cholesterol(TC),LDL,and HDL)in different groups were examined.Simultaneously,HE staining and oil red O staining were carried out on liver tissues to study histopathological changes in liver tissues of NAFLD rats after Qushi Kaiyu decoction intervention.ELISA was used to measure serum levels of inflammatory factors(IL-1β,IL-6,TNF-α)in various groups and to preliminarily study the effector mechanisms of how Qushi Kaiyu decoction alleviates NAFLD.Results:Qushi Kaiyu decoction can significantly decrease the body weight and liver index of NAFLD rats,decreases serum TG,TC,and LDL levels,and increases HDL levels.HE staining and oil red O staining showed that Qushi Kaiyu decoction could improve steatosis in NAFLD rat liver tissues and decrease lipid content.Additionally,ELISA results showed that the Qushi Kaiyu decoction could significantly reduce the serum levels of inflammatory factors(IL-1β,IL-6,TNF-α)in NAFLD rats.Conclusion:The Qushi Kaiyu decoction shows significant therapeutic efficacy in NAFLD,and its effector mechanism may be related to the alleviation of inflammatory responses.展开更多
文摘Cervical spondylosis of vertebral artery type is one of the chief patterns of cervical spondylosis.It is often described as neck pain accompanied with radiating pain and neurologic symptoms,such as sudden dizziness,blurred vision,tinnitus,nausea,vomiting,memory loss,and sudden fainting.The incidence of cervical spondylosis increases and patients with cervical spondylosis become progressively younger.Acupuncture in the cervical spondylosis of vertebral artery type treatment has a local positive reaction“Liuhe point”,in order to dredge the local Qi and blood.More and more evidences into the effectiveness and safety of cervical spine acupuncture for cervical spondylosis,specific neck pain,cervical radiculopathy,etc.This article summarizes the recent literature on acupuncture and acupuncture combined with other therapies for cervical spondylosis of vertebral artery type treatment and provides a comprehensive review from the perspectives of acupuncture therapy,warm needle moxibustion therapy,electroacupuncture,and acupuncture combined with other therapies,in order to provide reference and reference for clinical treatment.
基金This work was supported by Foundation of Chinese National University Student Innovation and Entrepreneurship Training Program(No.202010063002)Foundation of Innovation and Entrepreneurship Training Program of Tianjin University of Traditional Chinese Medicine(No.CXJJ2020ZF01).
文摘Objective:To examine the therapeutic effects of the Traditional Chinese Medicine Qushi Kaiyu decoction on Non-alcoholic fatty liver disease(NAFLD)rats and relevant mechanisms.Methods:A NAFLD rat model was constructed in this study using a high-fat diet,and different Qushi Kaiyu decoction doses were administered by gavage.The body weight,liver index,and blood lipid biochemical markers(TG,Total cholesterol(TC),LDL,and HDL)in different groups were examined.Simultaneously,HE staining and oil red O staining were carried out on liver tissues to study histopathological changes in liver tissues of NAFLD rats after Qushi Kaiyu decoction intervention.ELISA was used to measure serum levels of inflammatory factors(IL-1β,IL-6,TNF-α)in various groups and to preliminarily study the effector mechanisms of how Qushi Kaiyu decoction alleviates NAFLD.Results:Qushi Kaiyu decoction can significantly decrease the body weight and liver index of NAFLD rats,decreases serum TG,TC,and LDL levels,and increases HDL levels.HE staining and oil red O staining showed that Qushi Kaiyu decoction could improve steatosis in NAFLD rat liver tissues and decrease lipid content.Additionally,ELISA results showed that the Qushi Kaiyu decoction could significantly reduce the serum levels of inflammatory factors(IL-1β,IL-6,TNF-α)in NAFLD rats.Conclusion:The Qushi Kaiyu decoction shows significant therapeutic efficacy in NAFLD,and its effector mechanism may be related to the alleviation of inflammatory responses.