期刊文献+
共找到10篇文章
< 1 >
每页显示 20 50 100
Streptococcus anginosus in the development and treatment of precancerous lesions of gastric cancer
1
作者 Su-Ting Qian hao-yu zhao +2 位作者 Fei-Fei Xie Qing-Sheng Liu Dan-Li Cai 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第9期3771-3780,共10页
The microbiota is strongly association with cancer.Studies have shown significant differences in the gastric microbiota between patients with gastric cancer(GC)patients and noncancer patients,suggesting that the micro... The microbiota is strongly association with cancer.Studies have shown significant differences in the gastric microbiota between patients with gastric cancer(GC)patients and noncancer patients,suggesting that the microbiota may play a role in the development of GC.Although Helicobacter pylori(H.pylori)infection is widely recognized as a primary risk factor for GC,recent studies based on microbiota sequencing technology have revealed that non-H.pylori microbes also have a significant impact on GC.A recent study discovered that Streptococcus anginosus(S.anginosus)is more prevalent in the gastric mucosa of patients with GC than in that of those without GC.S.anginosus infection can spontaneously induce chronic gastritis,mural cell atrophy,mucoid chemotaxis,and heterotrophic hyperplasia,which promote the development of precancerous lesions of GC(PLGC).S.anginosus also disrupts the gastric barrier function,promotes the proliferation of GC cells,and inhibits apoptosis.However,S.anginosus is underrepresented in the literature.Recent reports suggest that it may cause precancerous lesions,indicating its emerging pathogenicity.Modern novel molecular diagnostic techniques,such as polymerase chain reaction,genetic testing,and Ultrasensitive Chromosomal Aneuploidy Detection,can be used to gastric precancerous lesions via microbial markers.Therefore,we present a concise summary of the relationship between S.anginosus and PLGC.Our aim was to further investigate new methods of preventing and treating PLGC by exploring the pathogenicity of S.anginosus on PLGC. 展开更多
关键词 Streptococcus anginosus Gastric cancer Precancerous lesions of gastric cancer MICROBIOTA Microbiota sequencing technology
下载PDF
Prospects in the application of ultrasensitive chromosomal aneuploidy detection in precancerous lesions of gastric cancer
2
作者 Su-Ting Qian Fei-Fei Xie +2 位作者 hao-yu zhao Qing-Sheng Liu Dan-Li Cai 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第1期6-12,共7页
Gastric cancer(GC)is a prevalent malignant tumor within the digestive system,with over 40%of new cases and deaths related to GC globally occurring in China.Despite advancements in treatment modalities,such as surgery ... Gastric cancer(GC)is a prevalent malignant tumor within the digestive system,with over 40%of new cases and deaths related to GC globally occurring in China.Despite advancements in treatment modalities,such as surgery supplemented by adjuvant radiotherapy or chemotherapeutic agents,the prognosis for GC remains poor.New targeted therapies and immunotherapies are currently under invest-igation,but no significant breakthroughs have been achieved.Studies have indicated that GC is a heterogeneous disease,encompassing multiple subtypes with distinct biological characteristics and roles.Consequently,personalized treatment based on clinical features,pathologic typing,and molecular typing is crucial for the diagnosis and management of precancerous lesions of gastric cancer(PLGC).Current research has categorized GC into four subtypes:Epstein-Barr virus-positive,microsatellite instability,genome stability,and chromosome instability(CIN).Technologies such as multi-omics analysis and gene sequencing are being employed to identify more suitable novel testing methods in these areas.Among these,ultrasensitive chromosomal aneuploidy detection(UCAD)can detect CIN at a genome-wide level in subjects using low-depth whole genome sequencing technology,in conjunction with bioinformatics analysis,to achieve qualitative and quantitative detection of chromosomal stability.This editorial reviews recent research advancements in UCAD technology for the diagnosis and management of PLGC. 展开更多
关键词 Gastric cancer Precancerous lesions of gastric cancer Molecular typing Ultrasensitive chromosomal aneuploidy detection Adjuvant therapy Application prospects
下载PDF
Investigation of single event effect in 28-nm system-on-chip with multi patterns 被引量:2
3
作者 Wei-Tao Yang Yong-Hong Li +8 位作者 Ya-Xin Guo hao-yu zhao Yang Li Pei Li Chao-Hui He Gang Guo Jie Liu Sheng-Sheng Yang Heng An 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第10期573-577,共5页
Single event effects (SEEs) in a 28-nm system-on-chip (SoC) were assessed using heavy ion irradiations, and susceptibilities in different processor configurations with data accessing patterns were investigated. The pa... Single event effects (SEEs) in a 28-nm system-on-chip (SoC) were assessed using heavy ion irradiations, and susceptibilities in different processor configurations with data accessing patterns were investigated. The patterns included the sole processor (SP) and asymmetric multiprocessing (AMP) patterns with static and dynamic data accessing. Single event upset (SEU) cross sections in static accessing can be more than twice as high as those of the dynamic accessing, and processor configuration pattern is not a critical factor for the SEU cross sections. Cross section interval of upset events was evaluated and the soft error rates in aerospace environment were predicted for the SoC. The tests also indicated that ultra-high linear energy transfer (LET) particle can cause exception currents in the 28-nm SoC, and some even are lower than the normal case. 展开更多
关键词 SYSTEM-ON-CHIP heavy ion single event effect
下载PDF
Direct ink writing of multifunctional gratings with gel-like MXene/norepinephrine ink for dynamic electromagnetic interference shielding and patterned Joule heating 被引量:1
4
作者 Pei-Zhu Jiang Zhiming Deng +6 位作者 Peng Min Lvxuan Ye Cheng-Zhang Qi hao-yu zhao Ji Liu Hao-Bin Zhang Zhong-Zhen Yu 《Nano Research》 SCIE EI CSCD 2024年第3期1585-1594,共10页
Intelligent electromagnetic interference(EMI)shielding modulators with a wide tuning range and cyclic stability are urgently needed but their fabrication remains challenging.A gel-like MXene/norepinephrine ink is deve... Intelligent electromagnetic interference(EMI)shielding modulators with a wide tuning range and cyclic stability are urgently needed but their fabrication remains challenging.A gel-like MXene/norepinephrine ink is developed and multifunctional MXene gratings with wide EMI shielding effectiveness(SE)tuning range,superior reversibility,and high mechanical flexibility are constructed by direct ink writing approach for dynamic EMI shielding and patterned Joule heating applications.The modulable MXene/norepinephrine grating with a high conductivity of 3510 S·cm-1 can conveniently realize the seamless modulation of the EMI SE by adjusting the angle between the MXene grating filaments and the electric field of the incident electromagnetic waves,offering highly reversible switching between shielding“On”(28.0 dB)and“Off”(0.5 dB)states.Notably,due to the optimized integration of the MXene ink and the rationally designed pattern,a superior specific EMI SE of 95,688.2 dB·cm^(2)·g^(-1) is achieved in the“On”state.Furthermore,the MXene/norepinephrine ink can be used to fabricate many complex patterned gratings with superior stability,instant responsibility,and superb mechanical flexibility,exhibiting a unique patterned Joule heating behavior.Direct writing of multifunctional gratings paves a means for developing intelligent EMI shielding materials,wearable electronic devices,and advanced thermal management materials. 展开更多
关键词 MXene ink direct ink writing electromagnetic interference shielding multifunctional gratings Joule heating
原文传递
Constructing central hollow cylindrical reduced graphene oxide foams with vertically and radially orientated porous channels for highly efficient solar-driven water evaporation and purification 被引量:1
5
作者 Changjun Li Wei Li +3 位作者 hao-yu zhao Xin-Yue Feng Xiaofeng Li Zhong-Zhen Yu 《Nano Research》 SCIE EI CSCD 2023年第5期6343-6352,共10页
Although solar steam generation is an eco-friendly approach for desalinating seawater and purifying wastewater,there are still issues on how to improve the efficiency of solar energy utilization and accelerate the wat... Although solar steam generation is an eco-friendly approach for desalinating seawater and purifying wastewater,there are still issues on how to improve the efficiency of solar energy utilization and accelerate the water and heat transport inside the solardriven water evaporators.Herein,we design a central hollow cylindrical reduced graphene oxide(RGO)foam with vertically and radially orientated channels as a solar steam generation device for efficient water evaporation and purification.The vertically aligned porous channels accelerate upward transport of water to the top evaporation surface,while the radially aligned porous channels facilitate water transport and heat transfer along the radial directions for fully utilizing the heat accumulated inside the central cylindrical hole of the foam.The central hole of the foam plays a highly positive role in accumulating more heat for accelerating the water evaporation,the newly generated inner sidewall resulted from the central hole can gain extra thermal energy from surrounding environment in the same way as the outer sidewall of the foam due to the surface cooling effect of the water evaporation.As a result,the vertically and radially aligned RGO foam evaporator with central hollow cylinder achieves a high solar steam generation rate of 2.32 kg·m^(−2)·h^(−1)with an exceptional energy conversion efficiency of 120.9%under 1-sun irradiation,superior to the vertically aligned RGO foam without the central hole(1.83 kg·m^(−2)·h^(−1),96.9%)because of the enhanced water and heat transfer inside the porous channels,the efficient utilization of environmental energy. 展开更多
关键词 hollow cylindrical foams reduced graphene oxide solar steam generation water evaporation rate seawater desalination
原文传递
Sponge-templating synthesis of sandwich-like reduced graphene oxide nanoplates with confined gold nanoparticles and their enhanced stability for solar evaporation 被引量:4
6
作者 Hong-Wu Zhu Jin Ge +4 位作者 hao-yu zhao Lu-An Shi Jin Huang Liang Xu Shu-Hong Yu 《Science China Materials》 SCIE EI CSCD 2020年第10期1957-1965,共9页
Solar evaporation based on plasmonic metal nanoparticles(MNPs)is emerging as a promising technology.However,the fine structure of MNPs is unstable,and both the high temperature generated by intensive light and corrosi... Solar evaporation based on plasmonic metal nanoparticles(MNPs)is emerging as a promising technology.However,the fine structure of MNPs is unstable,and both the high temperature generated by intensive light and corrosive ions in water could damage them.The performance will decline after recycling and long-time usage.To address these issues,we adopted a sponge-templating method for preparing sandwich-like nanoplates with the gold nanoparticles(Au NPs)confined in reduced graphene oxide(rGO)nanosheets.Due to the confinement effect,both the surface melting and ion diffusion were suppressed.The solar evaporator based on the sandwich-like nanoplates showed a high solar-vapor conversion efficiency of 85.2%under a high light intensity of 10 kW.After 30 times recycle of seawater desalination,the conversion efficiency scarcely decreased.These sandwich-like nanoplates with enhanced thermal and chemical stability of Au NPs are promising in the practical application of seawater desalination. 展开更多
关键词 sponge template confinement effect surface melting DESALINATION
原文传递
Anisotanols A—D,Four Norsesquiterpenoids with an Unprece-dented Sesquiterpenoid Skeleton from Anisodus tanguticus 被引量:3
7
作者 hao-yu zhao Qin-Mei Zhou +6 位作者 Huan Zhu Fei Zhou Chun-Wang Meng Hong-Zhen Shu zhao-Hua Liu Cheng Peng Liang Xiong 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2021年第12期3375-3380,共6页
Anisotanols A—D(1-4),four new compounds possessing an unprecedented sesquiterpenoid skeleton with a congested tricyclic 6/3/5 ring system,were obtained from Anisodus tanguticus.Their structures were elucidated by com... Anisotanols A—D(1-4),four new compounds possessing an unprecedented sesquiterpenoid skeleton with a congested tricyclic 6/3/5 ring system,were obtained from Anisodus tanguticus.Their structures were elucidated by comprehensive spectroscopic techniques,and the absolute configurations were confirmed via ECD calculations and single-crystal X-ray diffractions.A putative biosynthetic pathway for these compounds was proposed.Biological evaluation disclosed that compound 3 showed anti-angiogenic activity by inhibiting the viability,migration,and tube formation in HUVECs. 展开更多
关键词 Anisodus tanguticus TERPENOIDS Structure elucidation Anisotane-type ANGIOGENESIS
原文传递
Printable elastic silver nanowire-based conductor for washable electronic textiles 被引量:2
8
作者 Hong-Wu Zhu Huai-Ling Gao +4 位作者 hao-yu zhao Jin Ge Bi-Cheng Hu Jin Huang Shu-Hong Yu 《Nano Research》 SCIE EI CAS CSCD 2020年第10期2879-2884,共6页
Printable elastic conductors promote the wide application of consumable electronic textiles (e-textiles) for pervasive healthcare monitoring and wearable computation. To assure a clean appearance, the e-textiles requi... Printable elastic conductors promote the wide application of consumable electronic textiles (e-textiles) for pervasive healthcare monitoring and wearable computation. To assure a clean appearance, the e-textiles require a washing process to clean up the dirt after daily use. Thus, it is crucial to develop low-cost printable elastic conductors with strong adhesion to the textiles. Here, we report a composite elastic conductor based on Ag nanowires (NWs) and polyurethane elastomer. The composite could be dispersed into ink and easily printed onto textiles. One-step print could form robust conductive coatings without sealing on the textiles. Interestingly, the regional concentration of Ag NWs within the polyurethane matrix was observed during phase inversion, endowing the elastic conductor with a low percolation threshold of 0.12 vol.% and high conductivity of 3,668 S·cm^−1. Thanks to the high adhesion of the elastic conductors, the resulted e-textiles could withstand repeated stretching, folding, and machine washing (20 times) without obvious performance decay, which reveals its potential application in consumable e-textiles. 展开更多
关键词 printable elastic conductor electronic textiles WASHABILITY phase inversion silver nanowires
原文传递
Dip-coating processed sponge-based electrodes for stretchable Zn-MnO2 batteries 被引量:2
9
作者 Hong-Wu Zhu Jin Ge +3 位作者 Yu-Can Peng hao-yu zhao Lu-An Shi Shu-Hong Yu 《Nano Research》 SCIE EI CAS CSCD 2018年第3期1554-1562,共9页
Stretchable electronics are in high demand for next-generation wearable devices, but their fabrication is still challenging. Stretchable conductors, flexible pressure sensors, and foldable light-emitting diodes (LEDs... Stretchable electronics are in high demand for next-generation wearable devices, but their fabrication is still challenging. Stretchable conductors, flexible pressure sensors, and foldable light-emitting diodes (LEDs) have been reported; however, the fabrication of stable stretchable batteries, as power suppliers for wearable devices, is significantly behind the development of other stretchable electronics. Several stretchable lithium-ion batteries and primary batteries have been fabricated, but their low capacities and complicated manufacturing processes are obstacles for practical applications. Herein, we report a stretchable zinc/manganese-oxide (Zn-MnO2) full battery based on a silver-nanowire- coated sponge prepared via a facile dip-coating process. The spongy electrode, with a three-dimensional (3D) binary network structure, provided not only high conductivity and stretchability, but also enabled a high mass loading of electrochemically active materials (Zn and MnO2 particles). The fabricated Zn-MnO2 battery exhibited an areal capacity as high as 3.6 mAh·cm^-2 and could accommodate tensile strains of up to 100% while retaining 89% of its original capacity. The facile solution-based strategy of dip-coating active materials onto a cheap sponge-based stretchable current collector opens up a new avenue for fabricating stretchable batteries. 展开更多
关键词 stretchable battery Zn-MnO2 batter silver nanowires sponge binary network structure
原文传递
Biomass-based biomimetic-oriented Janus nanoarchitecture for efficient heavy-metal enrichment and interfacial solar water sanitation
10
作者 hao-yu zhao Wei-Xu Dong +8 位作者 Yu Deng Li-Feng Chen Chen-Fan zhao Chuan-Ling Zhang Jie Zhou Yi-Fan Qu Yan-Song Li Dong-Jun Li Shu-Hong Yu 《Interdisciplinary Materials》 2022年第4期537-547,共11页
Interfacial solar steam generation(ISSG),involving the use of solar energy to evaporate water at the water-to-vapor interface,has presented prospects for the desalination and purification of water due to high energy c... Interfacial solar steam generation(ISSG),involving the use of solar energy to evaporate water at the water-to-vapor interface,has presented prospects for the desalination and purification of water due to high energy conversion efficiency and low-cost freshwater generation.Herein,inspired by the aligned nanostructure of plants for efficiently transporting nutrient ions,we optimally design and construct a biomass-based Janus architecture evaporator with an oriented nanostructure for ISSG,using the ice template method,followed by biomimetic mineralization with the resource-abundant and low-cost biomass of the carboxymethyl cellulose and sodium alginate as the raw materials.Taking advantage of the oriented nanostructure allowing efficient transportation of water and coordination capacity of sodium alginate for effective enrichment of heavy-metal ions,the biomass-based Janus architecture shows much lower thermal conductivity and an ultrahigh steam regeneration rate of 2.3 kg m−2 h−1,considerably surpassing those of previously reported oriented biomass-based evaporators.Moreover,the biomass precursor materials are used for this Janus evaporator,guaranteeing minimum impact on the water ecology and environment during the regeneration process of clean drinking water.This study presents an efficient,green,and sustainable pathway for ISSG to effectively achieve heavy-metal-free drinking water. 展开更多
关键词 biomass-based nanomaterials biomimetic-oriented nanostructure heavy-metal enrichment interfacial solar water sanitation Janus nanoarchitecture
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部