The purpose of this study was focused on the imaging features of the chest trauma and its relation to clinical characteristics. All the injured patients were from the Yushu Earthquake areas on days April 14 - 23,2010....The purpose of this study was focused on the imaging features of the chest trauma and its relation to clinical characteristics. All the injured patients were from the Yushu Earthquake areas on days April 14 - 23,2010. After an initial treatment,the injurers were rapidly transported from Yushu at an altitude of 4 000 m via air to Xining at 2 260 m within 6~8 h,and promptly admitted to Qinghai Provincial People’s Hospital. A total of 130 wounded injurers who had high suspicion of chest injuries all had examinations of Chest X-ray and computed tomography(CT)images. Of them 63 injurers presented at least one of the features of the chest trauma in imaging with a positive rate of 48.5 %. Of these,37 cases (28.5 %) were multi-system with multiple injuries ,33 cases (25.4 %) were chest trauma with multi-injury types,which included thoracic fractures in 54 cases (85.7 %),pleural injury in 56 cases (88.9 %),lung injury in 54 cases (85.7 %),lungs complications in 37 cases (58.7 %),and extrapulmonary complications of 35 cases (55.6 %). The radiological data were analyzed retrospectively. The features of chest trauma in Yushu Earthquake,the complications of chest injuries,and the relation between imaging findings and clinical manifestations,as well as the differences of chest trauma between Yushu Earthquake and Wenchuan Earthquake were discussed in detail.展开更多
目的探讨远端桡动脉入路(dTRA)穿刺在神经介入诊疗中的安全性和可行性。方法回顾性分析2020年10月至2022年3月在北京安贞医院接受dTRA选择性脑血管造影或支架植入术诊疗患者一般资料(年龄、性别、危险因素等)、临床资料(入手术室至穿刺...目的探讨远端桡动脉入路(dTRA)穿刺在神经介入诊疗中的安全性和可行性。方法回顾性分析2020年10月至2022年3月在北京安贞医院接受dTRA选择性脑血管造影或支架植入术诊疗患者一般资料(年龄、性别、危险因素等)、临床资料(入手术室至穿刺成功时间、手术时间、X线辐射时间、总辐射剂量)、手术相关并发症、穿刺相关并发症。结果共纳入患者34例,其中男26例,女8例,年龄(61.6±9.0)(33~74)岁。dTRA脑血管造影技术成功率为100%。入手术室至穿刺成功时间为(23.1±10.1)(9~50)min,手术时间为(46.1±27.4)(14~154)min,X线辐射时间为(17.7±12.3)(6~69)min,总辐射剂量为(671.6±334.3)(70~1573)mGy。造影完成后17例同期接受介入治疗,其中1例椎动脉起始段狭窄患者造影后拟行椎动脉支架植入术,因路径迂曲改为股动脉穿刺。dTRA行介入治疗技术成功率为94.1%(16/17)。术后24 h 1例颈动脉支架植入术患者出现急性支架内闭塞,急诊取栓后美国国立卫生研究院卒中量表(NIHSS)评分为0分。术后患者未出现穿刺点淤血、出血、血肿及桡动脉闭塞。结论dTRA行神经介入诊断和治疗安全可行。展开更多
钙调蛋白激酶Ⅱ(Ca^2+/calmodulin-dependent protein kinase,CaMKⅡ)是一种多功能的丝氨酸/苏氨酸蛋白激酶,在神经元中大量存在,广泛参与疼痛调制。神经病理痛是一种由疾病或躯体感觉系统的损伤引起的慢性难治性疼痛。钙调蛋白激酶Ⅱ...钙调蛋白激酶Ⅱ(Ca^2+/calmodulin-dependent protein kinase,CaMKⅡ)是一种多功能的丝氨酸/苏氨酸蛋白激酶,在神经元中大量存在,广泛参与疼痛调制。神经病理痛是一种由疾病或躯体感觉系统的损伤引起的慢性难治性疼痛。钙调蛋白激酶Ⅱ在中枢、外周神经病理痛、代谢型神经病理痛和药物引起神经病理痛等各种类型的神经病理痛的发生发展中发挥着重要的作用。本文拟将从钙调激酶Ⅱ介导的各型神经病理痛及其上下游的调控两个方面进行综述,以期为今后钙调蛋白激酶Ⅱ在神经病理痛领域的研究提供一定参考。展开更多
基金Project of Qinghai Development of Science and Technology (No.2011-N-150)
文摘The purpose of this study was focused on the imaging features of the chest trauma and its relation to clinical characteristics. All the injured patients were from the Yushu Earthquake areas on days April 14 - 23,2010. After an initial treatment,the injurers were rapidly transported from Yushu at an altitude of 4 000 m via air to Xining at 2 260 m within 6~8 h,and promptly admitted to Qinghai Provincial People’s Hospital. A total of 130 wounded injurers who had high suspicion of chest injuries all had examinations of Chest X-ray and computed tomography(CT)images. Of them 63 injurers presented at least one of the features of the chest trauma in imaging with a positive rate of 48.5 %. Of these,37 cases (28.5 %) were multi-system with multiple injuries ,33 cases (25.4 %) were chest trauma with multi-injury types,which included thoracic fractures in 54 cases (85.7 %),pleural injury in 56 cases (88.9 %),lung injury in 54 cases (85.7 %),lungs complications in 37 cases (58.7 %),and extrapulmonary complications of 35 cases (55.6 %). The radiological data were analyzed retrospectively. The features of chest trauma in Yushu Earthquake,the complications of chest injuries,and the relation between imaging findings and clinical manifestations,as well as the differences of chest trauma between Yushu Earthquake and Wenchuan Earthquake were discussed in detail.
文摘目的探讨远端桡动脉入路(dTRA)穿刺在神经介入诊疗中的安全性和可行性。方法回顾性分析2020年10月至2022年3月在北京安贞医院接受dTRA选择性脑血管造影或支架植入术诊疗患者一般资料(年龄、性别、危险因素等)、临床资料(入手术室至穿刺成功时间、手术时间、X线辐射时间、总辐射剂量)、手术相关并发症、穿刺相关并发症。结果共纳入患者34例,其中男26例,女8例,年龄(61.6±9.0)(33~74)岁。dTRA脑血管造影技术成功率为100%。入手术室至穿刺成功时间为(23.1±10.1)(9~50)min,手术时间为(46.1±27.4)(14~154)min,X线辐射时间为(17.7±12.3)(6~69)min,总辐射剂量为(671.6±334.3)(70~1573)mGy。造影完成后17例同期接受介入治疗,其中1例椎动脉起始段狭窄患者造影后拟行椎动脉支架植入术,因路径迂曲改为股动脉穿刺。dTRA行介入治疗技术成功率为94.1%(16/17)。术后24 h 1例颈动脉支架植入术患者出现急性支架内闭塞,急诊取栓后美国国立卫生研究院卒中量表(NIHSS)评分为0分。术后患者未出现穿刺点淤血、出血、血肿及桡动脉闭塞。结论dTRA行神经介入诊断和治疗安全可行。
文摘钙调蛋白激酶Ⅱ(Ca^2+/calmodulin-dependent protein kinase,CaMKⅡ)是一种多功能的丝氨酸/苏氨酸蛋白激酶,在神经元中大量存在,广泛参与疼痛调制。神经病理痛是一种由疾病或躯体感觉系统的损伤引起的慢性难治性疼痛。钙调蛋白激酶Ⅱ在中枢、外周神经病理痛、代谢型神经病理痛和药物引起神经病理痛等各种类型的神经病理痛的发生发展中发挥着重要的作用。本文拟将从钙调激酶Ⅱ介导的各型神经病理痛及其上下游的调控两个方面进行综述,以期为今后钙调蛋白激酶Ⅱ在神经病理痛领域的研究提供一定参考。
