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Plasma endothelin-1 and nitric oxide correlate with ligustrazine alleviation of pulmonary artery hypertension in patients of chronic cor pulmonale from high altitude plateau during acute exacerbation 被引量:11
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作者 En-zhi FENG Sheng-yue YANG +3 位作者 Ning-xia HUANG he yin ying ZHANG Zhong-xin TIAN 《中国应用生理学杂志》 CAS CSCD 2014年第6期532-537,共6页
Objective To explore the mechanisms involved in the ligustrazine alleviation of the pulmonary artery hypertension(PAH) in patients of chronic obstructive pulmonary disease(COPD) associated with chronic cor pulmonale(C... Objective To explore the mechanisms involved in the ligustrazine alleviation of the pulmonary artery hypertension(PAH) in patients of chronic obstructive pulmonary disease(COPD) associated with chronic cor pulmonale(CCP) during exacerbation.Methods Seventy patients of COPD and CCP with acute exacerbation were randomly and equally divided into control group and treatment group.The control group received standard treatment with antibiotics,antiasthmatic and expectorant medications,and oxygenation;and the ligustrazine treatment group received ligustrazine treatment(80 mg/d;i.v.;for 2 weeks) in addition to the standard treatment.Before and at the end of 2 week treatment,the clinic responses of the two regimens were evaluated,plasma levels of endothelin-1(ET-1) and nitric oxide(NO) were determined;arterial oxygen partial pressure(PaO_2),mean pulmonary arterial pressure(mPAP),outflow tract of right ventricle(RVOT),and internal diameter of right ventricle(RV) were measured.Results Good clinic benefits were achieved in both the standard and ligustrazine regimens,plasma level of ET-1,values of mPAP,RV and RVOT decreased significantly,plasma level of NO and PaO_2 values decreased(all P<0.01 vs pretreatment to all parameters).Compared with the control group,ligustrazine greatly enhanced the clinic efficacy from 77.1%to 97.1%(P<0.05),and also resulted in more significant changes of all these parameters(P<0.01 vs control group for all parameters).For both groups,the levels of plasma ET-1 were positively correlated with values of mPAP,RVOT,and RV(r = 0.710,0.853,and 0.766,respectively,all P = 0.000),and negatively correlated with plasma NO and PaO_2(r =- 0.823,and- 0.752,respectively,all P = 0.000).Conclusion Ligustrazine is effective in treating pulmonary artery hypertension during acute exacerbation of COPD and CCP in patients from the plateau area.The observed changes in the plasma levels of NO and ET-1 in response to ligustrazine treatment suggest that ligustrazine may act through the selective effect on pulmonary blood vessels to enhance the synthesis and release of NO and suppress those of ET-1 from lung vascular endothelial cells,thus reducing pulmonary artery pressure and decreasing pulmonary arterial hypertension. 展开更多
关键词 肺动脉高压 内皮素-1 川芎嗪 一氧化氮 高原地区 肺心病 急性 患者
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Changes in Schlemm’s canal,trabecular meshwork,and relevant parameters in the early stage after SMILE of myopia patients 被引量:1
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作者 Dan-Dan Yang Zhi-Qi Chen +3 位作者 Wei Chen he yin Jing-Kai Peng Jun-Ming Wang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2022年第2期291-298,共8页
AIM:To observe the changes in Schlemm’s canal(SC),trabecular meshwork(TM),and anterior chamber relevant parameters after small incision lenticule extraction(SMILE) of myopia patients.METHODS:A total of 58 eyes from 3... AIM:To observe the changes in Schlemm’s canal(SC),trabecular meshwork(TM),and anterior chamber relevant parameters after small incision lenticule extraction(SMILE) of myopia patients.METHODS:A total of 58 eyes from 30 patients who underwent SMILE were divided into a low and moderate myopia group(group A,32 eyes) and a high myopia group(group B,26 eyes).The diameter and area of the SC,the width and thickness of TM obtained by CIRRUS HD-OCT5000,and the related anterior chamber parameters obtained by Pentacam anterior segment analysis system,accommodation amplitude(AMP) were observed pre-and postoperatively.The preoperative intraocular pressure(IOP) and postoperative correction of intraocular pressure(IOPcc) were measured.RESULTS:The diameter and area of the SC in the two groups were significantly increased postoperatively(all P<0.01).The TM width of the patients in the two groups were increased at 1mo after surgery(both P<0.01),but the TM thickness did not change(P>0.05).The corneal curvature,central anterior chamber depth,and anterior chamber volume decreased after SMILE surgery(all P<0.01).There was a weak negative correlation between the SC area change and AMP change in group A(r=-0.362,P<0.01).The postoperative IOP decreased after correction by Shah formula(P<0.05).CONCLUSION:SC and TM in myopia patients change in the early postoperative stage of SMILE and the IOP is decline. 展开更多
关键词 Schlemm’s canal trabecular meshwork intraocular pressure MYOPIA small incision lenticule extraction
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无人机集群协同控制技术综述 被引量:1
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作者 张鹏飞 何印 +1 位作者 马振华 李亚文 《兵器装备工程学报》 CAS CSCD 北大核心 2024年第4期1-9,共9页
协同控制技术作为多智能体分工合作完成任务的关键核心技术,能解决无人机集群编队、队形重构和避障避碰等问题,是无人机集群正常运作的基础。针对近几年国内外无人机集群协同控制技术的发展历程,概述3种控制结构原理及其优缺点;分析了基... 协同控制技术作为多智能体分工合作完成任务的关键核心技术,能解决无人机集群编队、队形重构和避障避碰等问题,是无人机集群正常运作的基础。针对近几年国内外无人机集群协同控制技术的发展历程,概述3种控制结构原理及其优缺点;分析了基于3种控制结构的编队控制方法及其优缺点;从无人机集群协同编队控制技术出发,分析基于编队控制的避障方法;指出了现阶段无人机集群协同控制技术面临的瓶颈问题,并对协同控制技术的未来发展方向进行了展望,为无人机集群编队控制和避障方法研究提供一定的借鉴。 展开更多
关键词 无人机集群 协同控制 控制结构 编队控制 协同避障
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Source and accumulation process of Jurassic biodegraded oil in the Eastern Junggar Basin,NW China
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作者 Mao-Guo Hou Ming Zha +4 位作者 Xiu-Jian Ding he yin Bao-Li Bian Hai-Lei Liu Zhong-Fa Jiang 《Petroleum Science》 SCIE CAS CSCD 2021年第4期1033-1046,共14页
Biodegradation usually obscures or even radically alters the original characteristics of oil biomarkers.The mixing of oil from multiple sources makes each source difficult to trace.Identifying the source of biodegrade... Biodegradation usually obscures or even radically alters the original characteristics of oil biomarkers.The mixing of oil from multiple sources makes each source difficult to trace.Identifying the source of biodegraded oil from multiple sources has always been a hard nut to crack.Rising to this challenge,in this study-we carried out a comprehensive investigation of biodegradation impacts,oil-source correlation,and oil charging history to trace the source and reveal the mixing process of biodegraded oil in the Toutunhe Formation(J_(2)t)in the eastern Junggar Basin,NW China.The oil of this area was biodegraded to different extent,consequently,many commonly used biomarker parameters(e.g.Pr/Ph,Pr/n C_(17))became less powerful for oil-source correlation.To address this problem,the resistance of many biomarkers to biodegradation was analyzed,and those of high bio resistance were selected to generate a more reliable oil-source correlation.The results revealed that biodegraded oil was a mixture of oil sourced from Lucaogou Formation(P_(2)l)and Xiaoquangou Formation(T_(2-3)xq).Core sample observation,microscopic fluorescent analysis and fluid inclusion analysis were combined to analyze comprehensively oil charging history.The analysis of accumulation process exhibited that the existing oil in J_(2)t was a mixture originated from the P_(2)l and T_(2-3)xq source rocks in two separate charging stages when it underwent a complicated process of charging,biodegradation,recharging and mixing. 展开更多
关键词 Biodegraded oil Mixed oil Oil-source correlation Oil accumulation process Junggar Basin
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头孢曲松钠联合集束化管理措施对早期呼吸机相关肺炎的预防效果
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作者 何茵 盖恬恬 韩遵海 《中国药师》 CAS 2024年第6期1028-1033,共6页
目的观察头孢曲松钠(CRO)联合集束化管理措施(BM)对行机械通气(MV)的重症监护室(ICU)患者早期呼吸机相关肺炎(VAP)的预防效果。方法选择2022年5月至2023年4月首都医科大学附属北京同仁医院138例ICU行MV的患者。根据是否使用CRO分为CRO... 目的观察头孢曲松钠(CRO)联合集束化管理措施(BM)对行机械通气(MV)的重症监护室(ICU)患者早期呼吸机相关肺炎(VAP)的预防效果。方法选择2022年5月至2023年4月首都医科大学附属北京同仁医院138例ICU行MV的患者。根据是否使用CRO分为CRO组和非CRO(NCRO)组,两组患者住院期间均实施BM。观察并比较两组患者早期VAP发生率、死亡率、机械通气时间、ICU住院时间和总住院时间。此外,比较干预前和干预后(第7 d)两组患者炎症指标[C-反应蛋白(CRP)、降钙素原(PCT)和白细胞计数(WBC)]的变化情况。结果CRO组患者早期VAP发生率低于NCRO组(P<0.05)。CRO组患者死亡率低于NCRO组,但差异无统计学意义(P>0.05)。CRO组患者机械通气时间、ICU住院时间和总住院时间均短于NCRO组(P<0.05)。治疗前两组患者的CRP水平、血清PCT水平和WBC差异无统计学意义(P>0.05)。与治疗前比较,CRO组和NCRO组血清CRP水平、血清PCT水平和WBC均显著下降(P<0.05)。此外,第7天,CRO组血清CRP水平、血清PCT水平和WBC低于NCRO组(P<0.05)。结论CRO联合BM可降低行MV的ICU患者早期VAP发生率,缩短MV时间、ICU住院时间和总住院时间,并降低机体炎症反应水平。 展开更多
关键词 头孢曲松 集束化管理 早期呼吸机相关肺炎 预防 机械通气
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Manipulation for degenerative lumbar spondylolisthesis:A systematic review of randomized controlled trials
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作者 Zhiwei Liu Xiaokuan Qin +6 位作者 Kai Sun he yin Xin Chen Bowen Yang Xu Wang Xu Wei Liguo Zhu 《Journal of Traditional Chinese Medical Sciences》 2022年第2期121-127,共7页
Objective: To assess the effectiveness and safety of manipulation intervention for degenerative lumbar spondylolisthesis(DLS).Methods: This is a systematic review and meta-analysis. A full-scale retrieval method was p... Objective: To assess the effectiveness and safety of manipulation intervention for degenerative lumbar spondylolisthesis(DLS).Methods: This is a systematic review and meta-analysis. A full-scale retrieval method was performed until February 1, 2021, including nine databases. The homogeneity of different studies was summarized using the Review Manager. The quality of studies was determined with the Cochrane risk-of-bias tool.The evidence quality was graded with the Grading of Recommendations, Assessment, Development, and Evaluations approach.Results: A total of 6 studies involving 524 participants were included. The review demonstrated that manipulation has statistically significant improvements for treating DLS according to Japanese Orthopedic Association scores(mean difference, 3.76;95% confidence interval, 2.63 to 4.90;P <.001) and visual analog scale scores(mean difference,-1.50;95% confidence interval,-1.66 to-1.33;P <.001)compared to the control group. One study reported that the difference in the Oswestry Disability Index between the traction group and the combination of manipulation and traction group was statistically significant(P <.05), while another reported that manipulation treatment can significantly improve the lumbar spine rotation angle on X-ray images compared with the baseline data(P <.05). Moreover, the manipulation group(experimental group) had fewer adverse events than the lumbar traction group(control group).Conclusion: Manipulation intervention is more effective and safer for DLS. Nevertheless, large-scale randomized controlled trials are required to confirm the current conclusions. 展开更多
关键词 MANIPULATION Degenerative lumbar spondylolisthesis META-ANALYSIS Japanese orthopedic association Oswestry disability index Visual analog scale Randomized controlled trial
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Analysis of influencing factors of clinical effect of TCM treatment for degenerative lumbar spondylolisthesis
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作者 Lin Chen Ke-Xin Yang +7 位作者 Jie Yu Xun-Lu yin he yin Xu Wei Kai Sun Long Liang Xin Chen Li-Guo Zhu 《Journal of Hainan Medical University》 2020年第8期33-33,共1页
Objective:To explore the related factors that may affect the efficacy of traditional Chinese medicine in treating degenerative lumbar spondylolisthesis.Methods:A total of 535 patients with DLS who were treated in Wang... Objective:To explore the related factors that may affect the efficacy of traditional Chinese medicine in treating degenerative lumbar spondylolisthesis.Methods:A total of 535 patients with DLS who were treated in Wangjing Hospital of China Academy of Chinese Medical Sciences and other hospitals from June 2011 to October 2014 were selected.The central random system was used to randomly divide the treatment group and control group.This study included 267 patients in the treatment group using the traditional Chinese medicine program((lumbar spine reduction and lumbar spine rehabilitation),36 cases of severely missing data were excluded,and a total of 231 DLS patients were included.Observation indicators were selected using the Visual Analog Scale(VAS)and the Japanese Orthopaedic Association(JOA)for the evaluation of lumbar vertebral disorders.The clinical efficacy was evaluated using the JOA lumbar pain curative effect evaluation standard[7].[(Joa score after treatment-JOA score before treatment]/(out of 29 points-JOA score before treatment)]×100%.The JOA score and the change of the efficacy index of the patients were observed.According to the JOA efficacy index after the treatment,it was divided into significant effect(≥50%)and poor effect(<50%).Single-factor screening and multi-factor Logistic regression analysis were used.Gender,age,course of disease,BMI index,slip-off segment,slip-off direction,back pain VAS score,total JOA score,back pain-score,lower limb pain and numbness-score,walking ability-score,straight leg elevation test-score,Feeling-scoring,muscle strength-scoring,supine turn-scoring,standing action-scoring,washing action-scoring,standing posture and continuous standing-scoring,long sedentary-scoring,weight lifting and holding-scoring,walking-scoring 2.Bladder function-scores were assigned to logistic regression models for univariate analysis,and meaningful independent variables were screened for multivariate logistic regression.Results:No serious adverse reactions occurred in the patients included in this study.According to the comparison of JOA scores before and after treatment,the results of the index of efficacy index showed that the effective rate of DLS in this project was 96.6%,and a significant effect of 77.6%was achieved.Univariate Logistic regression analysis showed that the duration of disease,supine turn-scoring,washing action-scoring,prolonged sedentary-scoring,weight lifting and keeping-scoring had statistically significant effects on the inclusion of patients with significant efficacy(P<0.05);single factor logistic regression analysis of total score of JOA score before treatment was not statistically significant(P=0.215),but because it is important for evaluating the patient's condition,it was included in multifactor logistic regression analysis at the same time.Course of onset,supine turn-scoring,washing action-scoring,prolonged sedentary-scoring,weight lifting and holding-scoring,JOA score before treatment.Six independent variables were substituted into the two-class logistic regression model for multivariate analysis..Multivariate logistic regression analysis showed that the effects of total JOA score and supine turn-scoring before treatment on the efficacy of patients were statistically significant(P<0.05).There are many factors influencing the efficacy of traditional Chinese medicine treatment of DLS,and the probability of obtaining a significant effect for each additional point of JOA score and supine turn-score before treatment increases by 1.167 and 0.410 times,respectively.Conclusion:The clinical application of lumbar spine reduction combined with lumbar rehabilitation exercises in patients with degenerative lumbar spondylolisthesis with a higher total JOA score or a lower limit of supine turning can achieve better clinical results.This finding has certain guiding significance for the clinical application of this therapy in the treatment of DLS,and is beneficial to improving patient satisfaction and clinical effectiveness. 展开更多
关键词 Degenerative lumber SPONDYLOLISTHESIS Chinese treatment Logistic regression analysis JOA score
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An overview of the latest international guidelines on evidence-based knee osteoarthritis
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作者 Shuai-Qi Zhou Long Liang +7 位作者 Jie Yu Min-Shan Feng Xu Wei Ming Chen Jiaw-Wen Zhan he yin Xun-Lu yin Li-Guo Zhu 《Journal of Hainan Medical University》 2020年第5期52-55,共4页
Knee osteoarthritis(KOA)is the highest incidence of osteoarthritis,which seriously affects the quality of life of patients.In order to update the understanding of the disease,clear diagnostic criteria and appropriate ... Knee osteoarthritis(KOA)is the highest incidence of osteoarthritis,which seriously affects the quality of life of patients.In order to update the understanding of the disease,clear diagnostic criteria and appropriate treatment were proposed.In 2018 and 2019,the European Society for Clinical and Economic Aspects of Osteoporosis,Osteoarthritis and Musculoskeletal Diseases(ESCEO),the Association of the Scientific Medical Societies in Germany(AWMF)and Brazil successively formulated guidelines for knee osteoarthritis,which determined different guidance suggestions through systematic evaluation of a large number of literatures and evidence-based medical evidence analysis.This paper compares and interprets the guidelines,and discusses them according to the actual situation of our country for the reference of clinicians. 展开更多
关键词 Knee osteoarthritis International Guidelines Diagnosis and Treatment INTERPRETATION
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A Systematic Review and Meta-analysis for Duhuo Jisheng Decoction Combined with Manipulation in Treatment of Lumbar Disc Herniation
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作者 Kai Sun Li-Gu Zhuo +6 位作者 Xu Wei Jie Yu Min-Shan Feng he yin Long Liang Bin Tang Bo-Wen Yang 《Journal of Hainan Medical University》 2020年第1期32-38,共7页
Objective:To systematically evaluate the efficacy and safety of Duhuo Jisheng decoction combined with manipulation in the treatment of lumbar disc herniation.Method:We systematically searched 8 databases at home and a... Objective:To systematically evaluate the efficacy and safety of Duhuo Jisheng decoction combined with manipulation in the treatment of lumbar disc herniation.Method:We systematically searched 8 databases at home and abroad.Literature quality of the included studies was evaluated by the bias risk assessment tool of Cochrane collaboration network,and the Meta-analysis was performed by RevMan 5.3 software.Result:A total of 427 related literature were retrieved,and 12 studies were eventually included,involving 1153 patients.All studies were in Chinese.Meta-analysis results showed that the total effective rate of Duhuo Jisheng decoction combined with manipulation in the treatment of LDH was better than that of the control group(RR=1.23,95%CI[1.17,1.29],P<0.00001).Subgroup analysis showed that Duhuo Jisheng decoction combined with manipulation had a more significant effect than conventional treatment(RR=1.34,95%CI[1.20,1.50],P<0.00001),nonsteroidal anti-inflammatory drugs(RR=1.24,95%CI[1.12,1.37],P<0.0001),and Yaotongning capsules(RR=1.19,95%CI[1.10,1.29],P<0.0001).It has obvious advantages in improving VAS scores(MD=-1.19,95%CI-1.19[-1.87,-0.51],P=0.0006),but it has no obvious advantages in improving JOA scores(MD=2.6595%CI[0.06,5.24],P=0.05).In terms of safety,Duhuo Jisheng decoction combined with manipulation treatment reported fewer adverse events.Conclusion:The Duhuo Jisheng decoction combined with manipulation treatment can effectively relieve the clinical symptoms of patients with lumbar disc herniation,with obvious clinical efficacy,and fewer adverse events.But in view of the limitations of clinical studies,there are some limitations in this study,and more studies with high quality of evidence are needed to further confirm its efficacy and safety. 展开更多
关键词 Duhuo Jisheng DECOCTION LUMBAR MANIPULATION LUMBAR DISC HERNIATION Systematic review META-ANALYSIS
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Evaluation of the quality of randomized controlled trials on exercise for cervical radiculopathy
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作者 Long Liang Jie Yu +8 位作者 Min-Shan Feng Shuai-Qi Zhou he yin Gong-Bo Yang Xun-Luyin Kai-Ming Li Rong Xie Xu Wei Li-Guo Zhu 《Journal of Hainan Medical University》 2019年第13期65-71,共7页
Objective:To review and evaluate the quality of the randomized controlled trials of exercise for the treatment of cervical radiculopathy with the present internationally recognized CONSORT statement, which provides re... Objective:To review and evaluate the quality of the randomized controlled trials of exercise for the treatment of cervical radiculopathy with the present internationally recognized CONSORT statement, which provides reference and basis for the improvement of clinical research on exercise for intervening cervical radiculopathy in the future.Methods: A computer-based search of large domestic databases, including CNKI, Wanfang database and VIP database screened out literature that meet the requirements and used CONSORT statement for quality assessment.Results: According to the prescribed inclusion and exclusion criteria, 30 articles were retrieved in accordance with the standard. No literature was referred to the randomized controlled trial, 2 documents clearly defined the type of test design, 1 documents carried out the calculation of sample size, 13 documents clearly randomly assigned, 1 literature implemented the blind method, in the 7 literature, baseline information was shown in tabular form, and no reference was made to trial registration, trial protocol and funding.Conclusion:There are some aspects of randomized controlled trials on exercise for the treatment of cervical radiculopathy. However, there are some aspects that need to be improved. In the future randomized controlled trial report, the CONSORT statement should be highly valued and carefully considered to improve the accuracy and credibility of the research. 展开更多
关键词 CERVICAL RADICULOPATHY EXERCISE Randomized controlled trials QUALITY EVALUATION CONSORT statement
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China to Make a New Chapter of Human Rights with the Rest of the World
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作者 he yin 《China Today》 2021年第8期12-12,共1页
THE 47th session of the UN Human Rights Council concluded on July 14 in Geneva,Switzerland.China’s stance on human rights was widely supported and responded to at the session,and the country also received high evalua... THE 47th session of the UN Human Rights Council concluded on July 14 in Geneva,Switzerland.China’s stance on human rights was widely supported and responded to at the session,and the country also received high evaluation for its sense of responsibility to drive the progress of human rights of the world. 展开更多
关键词 HUMAN RIGHTS Geneva
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Learn Chinese and Western Culture From the "Kung Fu Panda"
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作者 he yin 《International English Education Research》 2016年第4期23-25,共3页
This paper introduces the film "Kung Fu Panda," which contains the elements of Chinese culture and Western culture, respectively, from the philosophical thinking, animal image, folk life and expression of Chinglish ... This paper introduces the film "Kung Fu Panda," which contains the elements of Chinese culture and Western culture, respectively, from the philosophical thinking, animal image, folk life and expression of Chinglish and etiquette introduced Chinese elements, from individualism, fatalism and character introduced western culture reflected in the movie.The success of the film in the world shows that the new trend of the integration of Chinese and Western culture in the context of globalization. At the end of the paper, it gives the inspiration of the film "Kung Fu Panda" to the Chinese culture communication. 展开更多
关键词 Kung Fu Panda Chinese and Western culture traditional culture
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重症监护病房护士面对患者死亡情感体验的定性研究 被引量:1
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作者 孙萌 岳鹏 +1 位作者 何茵 王国艳 《中国心理卫生杂志》 CSCD 北大核心 2024年第5期413-418,共6页
目的:了解重症监护病房(Intensive Care Unit,ICU)护士面对患者死亡的情感体验,探究存在替代性创伤反应的ICU护士面对患者死亡的情感体验。方法:本研究采用描述性现象学的研究设计,选取ICU存在替代性创伤反应(灾难救助者替代性创伤问卷... 目的:了解重症监护病房(Intensive Care Unit,ICU)护士面对患者死亡的情感体验,探究存在替代性创伤反应的ICU护士面对患者死亡的情感体验。方法:本研究采用描述性现象学的研究设计,选取ICU存在替代性创伤反应(灾难救助者替代性创伤问卷各因子及总分超过理论中值)的责任护士16例,对其个体生活的参考框架、自我能力、自我资源、心理需求与认知图式和意象进行深入访谈,运用Colaizzi7步分析法进行资料分析。结果:ICU护士面对患者死亡的情感体验归纳为应激刺激下的自我防御和持续浸润后的情感内耗2个主题,其中应激刺激下的自我防御包括无意识的短暂封闭和个人化的情绪反应;持续浸润后的情绪内耗包括镜像复制患方情绪、尸体料理触发终结感、安慰家属束手无策、难以避免承担责任、消磨职业的归属感以及家庭成员关系严峻。结论:本研究总结了ICU护士面对患者死亡的双重情感体验,即应激刺激下的自我防御和持续浸润后的情感内耗。 展开更多
关键词 重症监护病房 护士 死亡 定性研究
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改进APF的无人机编队避障最优一致性控制方法 被引量:2
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作者 李亚文 张鹏飞 +1 位作者 何印 马振华 《航天控制》 CSCD 2024年第1期17-23,共7页
针对传统人工势场(Artificial Potential Field,APF)解决避障问题时出现的局部极小值、目标不可达等缺点,提出了一种结合APF和具有协同避障效果的最优一致性控制方法。基于固定无向通信拓扑的双积分器无人机编队模型,引入具有避障代价... 针对传统人工势场(Artificial Potential Field,APF)解决避障问题时出现的局部极小值、目标不可达等缺点,提出了一种结合APF和具有协同避障效果的最优一致性控制方法。基于固定无向通信拓扑的双积分器无人机编队模型,引入具有避障代价函数的最优一致性控制协议,解决APF避障的局限性问题,同时对多无人机进行编队控制,使无人机编队控制系统的一致性性能指标、控制消耗性能指标和避障性能指标达到最优解。此外,通过对每架无人机构建虚拟斥力势场,防止在避障过程中出现机间碰撞。仿真结果表明,与改进APF的非最优一致性控制相比,本文提出的改进APF的最优一致性控制能够缩短任务用时32%,且能够极大程度上保持队形完整性,减少避障所造成的一致性消耗和控制损耗。 展开更多
关键词 无人机编队 协同避障 人工势场法 最优一致性控制
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冬季运动智能柔性人台关键技术开发
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作者 何崟 邓凌 +4 位作者 林美霞 李倩倩 肖爽 刘皓 刘莉 《纺织学报》 EI CAS CSCD 北大核心 2024年第2期221-230,共10页
为精确获得运动姿态下服装对运动员整体和局部关键部位的减阻效果,基于运动员冬季运动动态姿势的三维人体数据,合理构建人台硬质内壳与柔性皮肤层的结构,并结合空气动力学等方法设计薄膜压电传感器的置入点位,为人台搭建完整的传感系统... 为精确获得运动姿态下服装对运动员整体和局部关键部位的减阻效果,基于运动员冬季运动动态姿势的三维人体数据,合理构建人台硬质内壳与柔性皮肤层的结构,并结合空气动力学等方法设计薄膜压电传感器的置入点位,为人台搭建完整的传感系统,开发了一款冬季运动智能柔性人台,并对该柔性人台进行了实际的风洞测试。结果表明,该人台可实现多点压力信号实时同步采集,不仅可得到人体局部关键部位的具体阻力数据,还可模拟测试速滑运动员在运动情况下穿着不同材料或不同结构设计的竞赛服装的减阻效果,测试竞赛服装不同部位的减阻情况。智能人台发挥了柔性传感器在服装减阻结构设计中的应用价值,使服装减阻测试更为简单和精确。 展开更多
关键词 柔性人台 柔性传感器 服装减阻 速滑服 冬季运动
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基于复合纳米纤维膜的离子传感器制备及其性能
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作者 梁文静 吴俊贤 +1 位作者 何崟 刘皓 《纺织学报》 EI CAS CSCD 北大核心 2024年第4期15-23,共9页
为开发具有高稳定性、高灵敏度的柔性离子传感器,采用静电纺丝法制备聚偏二氟乙烯(PVDF)/离子液体(IL)复合纳米纤维膜,与电极材料组装成三明治结构的离子传感器。探讨了纺丝液质量分数及IL含量对纺丝工艺和纤维膜形貌的影响;其次利用能... 为开发具有高稳定性、高灵敏度的柔性离子传感器,采用静电纺丝法制备聚偏二氟乙烯(PVDF)/离子液体(IL)复合纳米纤维膜,与电极材料组装成三明治结构的离子传感器。探讨了纺丝液质量分数及IL含量对纺丝工艺和纤维膜形貌的影响;其次利用能量色散X射线光谱仪和红外光谱仪表征了复合纳米纤维膜所含元素分布与化学结构;进一步利用柔性传感器测试系统探究了不同IL含量、不同厚度的纳米纤维膜对于传感器性能的影响。结果表明:在PVDF质量分数为18%~19%,且与离子液体量比为2∶1或3∶1时,复合纳米纤维膜表面规整,串珠少,纤维直径分布均匀,带电离子数量增多且分布均匀;随着PVDF/IL纳米纤维膜的厚度增加,离子传感器的检测范围逐渐增大,灵敏度逐渐降低;在聚偏二氟乙烯质量分数为18%,且与离子液体的量比为2∶1时,离子传感器在0~40 kPa的检测范围内具有32.471 pF/kPa灵敏度的压力感测,在5000次加载-循环中保持突出的力学稳定性,并且可应用于分辨人体关节运动的检测。 展开更多
关键词 聚偏二氟乙烯 离子液体 静电纺丝 纳米纤维膜 柔性离子传感器
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可穿戴脉搏监测传感器的制备及性能研究
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作者 何崟 乔智超 +1 位作者 刘皓 周鹏 《棉纺织技术》 CAS 2024年第11期1-8,共8页
为解决柔性压阻传感器在实际应用中传感性能不稳定、可靠性差等问题,采用改性石墨为导电材料,聚氨酯为柔性基底,通过溶液混合法制备了改性石墨/聚氨酯复合薄膜,并将其与丝网印刷织物电极组装成柔性压阻传感器。测试表征了制备样品的微... 为解决柔性压阻传感器在实际应用中传感性能不稳定、可靠性差等问题,采用改性石墨为导电材料,聚氨酯为柔性基底,通过溶液混合法制备了改性石墨/聚氨酯复合薄膜,并将其与丝网印刷织物电极组装成柔性压阻传感器。测试表征了制备样品的微观形貌、化学结构、力学性能、电学性能以及柔性压阻传感器的性能,并利用单因素方差分析和Kruskal-Wallis检验方法研究了传感器性能的差异性。结果表明:在0 kPa~3 kPa的压力范围内,传感器灵敏度最高可达到137.670 kPa^(-1);其灵敏度、迟滞性、响应时间、恢复时间以及重复性误差等性能在95%的置信区间下均无显著性差异;制备的传感器能够准确识别出不同位置脉搏信号。认为:该传感器具有一致的传感性能,能够应用于可穿戴脉搏监测系统中。 展开更多
关键词 改性石墨 复合薄膜 柔性压阻传感器 电学性能 灵敏度 差异性检验 脉搏监测
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Acute upper gastrointestinal bleeding due to portal hypertension in a patient with primary myelofibrosis:A case report 被引量:1
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作者 Yu Chen Bing-Bing Kong +3 位作者 he yin Hao Liu Sheng Wu Ting Xu 《World Journal of Clinical Cases》 SCIE 2024年第15期2621-2626,共6页
BACKGROUND Acute upper gastrointestinal bleeding is a common medical emergency that has a 10%hospital mortality rate.According to the etiology,this disease can be divided into acute varicose veins and nonvaricose vein... BACKGROUND Acute upper gastrointestinal bleeding is a common medical emergency that has a 10%hospital mortality rate.According to the etiology,this disease can be divided into acute varicose veins and nonvaricose veins.Bleeding from esophageal varices is a life-threatening complication of portal hypertension.Portal hypertension is a clinical syndrome defined as a portal venous pressure that exceeds 10 mmHg.Cirrhosis is the most common cause of portal hypertension,and thrombosis of the portal system not associated with liver cirrhosis is the second most common cause of portal hypertension in the Western world.Primary myeloproliferative disorders are the main cause of portal venous thrombosis,and somatic mutations in the Janus kinase 2 gene(JAK2 V617F)can be found in approximately 90% of polycythemia vera,50% of essential thrombocyrosis and 50% of primary myelofibrosis.CASE SUMMARY We present a rare case of primary myelofibrosis with gastrointestinal bleeding as the primary manifestation that presented as portal-superior-splenic mesenteric vein thrombosis.Peripheral blood tests revealed the presence of the JAK2 V617F mutation.Bone marrow biopsy ultimately confirmed the diagnosis of myelofibrosis(MF-2 grade).CONCLUSION In patients with acute esophageal variceal bleeding due to portal hypertension and vein thrombosis without cirrhosis,the possibility of myeloproliferative neoplasms should be considered,and the JAK2 mutation test should be performed. 展开更多
关键词 Acute esophageal variceal bleeding Portal hypertension MYELOFIBROSIS JAK2 V617F mutation Case report
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三语迁移研究:回顾与展望
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作者 何音 王保昌 苏炎奎 《武夷学院学报》 2024年第4期47-53,共7页
在外语教育领域,语言迁移问题一直备受关注。近年来随着二语习得研究向三语和多语习得的转向,三语迁移问题也成为三语习得研究中国内外学者关注的焦点之一,因此有必要对现有研究进行回顾总结。从语言迁移的定义、三语迁移的表现、迁移... 在外语教育领域,语言迁移问题一直备受关注。近年来随着二语习得研究向三语和多语习得的转向,三语迁移问题也成为三语习得研究中国内外学者关注的焦点之一,因此有必要对现有研究进行回顾总结。从语言迁移的定义、三语迁移的表现、迁移来源、影响迁移的因素四个方面对国内外既往研究进行梳理评述,在此基础上分析现有研究的不足,并对未来研究方向提出建议,以期为三语研究和三语教育提供参考。 展开更多
关键词 三语习得 语言迁移 述评
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肺癌胸腔镜术患者快速康复护理质量评价指标体系的建立与应用
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作者 涂海燕 张莹 +3 位作者 何银 陈珏玮 夏容 龚萍 《护理实践与研究》 2024年第9期1343-1350,共8页
目的建立肺癌胸腔镜术患者快速康复护理质量评价指标体系,并在临床加以应用,以检验其应用效果。方法通过文献分析法获取肺癌胸腔镜术患者快速康复护理质量评价指标,并经德尔菲法专家函询对指标进行筛选、修订,据此建立肺癌胸腔镜术患者... 目的建立肺癌胸腔镜术患者快速康复护理质量评价指标体系,并在临床加以应用,以检验其应用效果。方法通过文献分析法获取肺癌胸腔镜术患者快速康复护理质量评价指标,并经德尔菲法专家函询对指标进行筛选、修订,据此建立肺癌胸腔镜术患者快速康复护理质量评价指标体系。选择湖北省鄂州市中心医院2021年1月-2022年2月、2022年3月-2023年4月收治的肺癌胸腔镜术患者各55例为研究对象,自2022年3月起应用肺癌胸腔镜术患者快速康复护理质量评价指标体系,之前采用常规护理管理,根据指标体系应用前、后分为对照组、观察组,比较两组患者康复效果及护理满意度。结果两轮函询问卷回收率分别为94.12%、100%,专家权威度分别为0.850、0.881,函询意见协调度肯德尔和谐系数分别为0.427(χ^(2)=31.842,P<0.001)、0.474(χ^(2)=52.018,P<0.001),构建的肺癌胸腔镜术患者快速康复护理质量评价指标体系包含一级指标3个,二级指标7个,三级指标41个,变异系数为0.06~0.13。评价指标体系应用显示,观察组患者各康复指标评价均优于对照组(P<0.05),观察组患者护理满意度评价高于对照组(P<0.05)。结论肺癌胸腔镜术患者快速康复护理质量评价指标体系科学性、可靠性表现出色,其在临床中的应用,可实现对肺癌胸腔镜术患者快速康复护理质量的持续评价、改进,能促进患者术后快速康复,有助于提升护理满意度。 展开更多
关键词 肺癌 胸腔镜术 快速康复护理 护理质量 指标体系
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