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A Transparent Polyimide Film as a Biological Cell Culture Sheet with Microstructures 被引量:1
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作者 Hirotaka Maenosono hirofumi saito Yasushiro Nishioka 《Journal of Biomaterials and Nanobiotechnology》 2014年第1期17-23,共7页
The research on stem cell cultures has attracted much attention due to the recent development of regenerative medicine. Therefore, higher functionalities for devices used for culturing cells are strongly demanded. In ... The research on stem cell cultures has attracted much attention due to the recent development of regenerative medicine. Therefore, higher functionalities for devices used for culturing cells are strongly demanded. In this study, we fabricated cell culture sheets using transparent polyimide (PI), parylene (PA), and polyetheretherketone (PEEK) to make polymer materials that had microstructures. We then cultured stromal marrow cells (OP9) on them and investigated the cell alignment within the microstructures. Hot embossing was used to fabricate the microstructures with a width and depth of 5 μm on the polymer substrates. Cultivation of the cells was confirmed on the transparent PI and PA sheets, however, it was not observed on the PEEK sheet. Slight alignment of the cells was also observed along with the microstructures. 展开更多
关键词 TRANSPARENT Polymide PARYLENE POLYETHERETHERKETONE OP9 Cell Hot EMBOSSING
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Visual Perception of Incomplete Human-Like Body Postures: A Near-Infrared Spectroscopy Study
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作者 Hiroshi Ito hirofumi saito +3 位作者 Misato Oi Tomoko Shiraishi Shuang Meng Victor Alberto Palacios 《Journal of Behavioral and Brain Science》 2014年第12期544-558,共15页
Previous studies have reported that the mirror neuron system plays a crucial role in social cognition. We examined whether the higher-order cognitive functions are involved in the activations in the mirror neuron area... Previous studies have reported that the mirror neuron system plays a crucial role in social cognition. We examined whether the higher-order cognitive functions are involved in the activations in the mirror neuron area when we perceive simplified pseudo-postures. We measured 14 participants’ brain activation during the posture-recognition task using near-infrared spectroscopy. The participants’ task was to observe five sequentially presented target pseudo-postures and judge whether a test pseudo-posture was identical to one of the preceding five target pseudo-postures. The results in the majority of participants (n = 10/14) revealed that the activity in the inferior frontal mirror neuron area is modulated by perception of human-likeness, but not in the remaining four participants (n = 4/14). These results suggest that the degree of the activation of higher-order cognitive functions, which may be engaged in the inhibitory and/or facilitative processing of human body or bodily movement, leads to the distinctive activities in the inferior frontal mirror neuron area. 展开更多
关键词 NEAR-INFRARED Spectroscopy (NIRS) MIRROR NEURON System Object PERCEPTION HUMAN Body
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