A Resource-Based Pricing Collaborative Approach for Mitigating DDoS Attack in Mobile Edge Computing

Resource-constrainted and located closer to users,edge servers are more vulnerable to Distributed Denial of Service(DDoS)attacks.In order to mitigate the impact of DDoS attacks on benign users,this paper designed a Resource-based Pricing Collaborative approach(RPC)in mobile edge computing.By introducing the influence of resource prices on requester in economics,a collaboration model based on resource pricing was established,and the allocation of user request was regarded as a game strategy to obtain the overall minimum offloading cost of the user in network.The article theoretically proved the existence and rationality of the Nash equilibrium.Finally,simulation results verified the effectiveness and feasibility of the proposed approach in two experimental scenes.Experimental results shows that RPC can effectively improve the network ability to mitigate DDoS attacks,and alleviate the adverse effects of server attacks under delay constraints.

Investigation on the mechanism of ginsenoside Rg3 in treating murine primary mammary tumor

A murine primary mammary tumor model was established to investigate the treatment with ginsenosides Rg3.The relationship between ginsenosides Rg3 and primary mammary tumor was explored.Mammary tumor was induced by using the 7,12-dimethybenz(a)anthracene(DMBA).Ginsenoside Rg3 was employed for treatment.The incidence of mammary tumor in every group was compared,and the expressions of vascular endothelial growth factor(VEGF)and microvessel density(MVD)were detected by immunohistochemical method.The cell cycle and apoptosis percentage were determined by means offlow cytometry.The incidence of tumor in treatment group was significantly lower than that in control group(60.00%vs 33.33%,P<0.05).The average diameter of mammary tumor was(0.86�0.27)cm in control group and(0.39�0.09)cm in treatment group,with the difference being significant between control and treatment groups(P<0.01).The MVD value was(31.9�5.3)in control group and(20.1�4.9)in treatment group,respectively.There was a significant difference between the two groups(P<0.05).The apoptosis percentage in control group was significantly lower than that in treatment group[(2.47�0.69)%vs(5.67�0.99)%,P<0.05].Ginsenoside Rg3 can play an antitumor role in primary mammary tumor model by inhibiting angiogenesis,cell cycle progression,and promoting cell apoptosis.