The Capture and Catalytic Conversion of CO_(2) by Dendritic Mesoporous Silica-Based Nanoparticles

Dendritic mesoporous silica nanoparticles own three-dimensional center-radial channels and hierarchical pores,which endows themselves with super-high specific surface area,extremely large pore volumes,especially accessible internal spaces,and so forth.Dissimilar guest species(such as organic groups or metal nanoparticles)could be readily decorated onto the interfaces of the channels and pores,realizing the functionalization of dendritic mesoporous silica nanoparticles for targeted applications.As adsorbents and catalysts,dendritic mesoporous silica nanoparticles-based materials have experienced nonignorable development in CO_(2)capture and catalytic conversion.This comprehensive review provides a critical survey on this pregnant subject,summarizing the designed construction of novel dendritic mesoporous silica nanoparticles-based materials,the involved chemical reactions(such as CO_(2)methanation,dry reforming of CH_(4)),the value-added chemicals from CO_(2)(such as cyclic carbonates,2-oxazolidinones,quinazoline-2,4(1H,3H)-diones),and so on.The adsorptive and catalytic performances have been compared with traditional silica mesoporous materials(such as SBA-15 or MCM-41),and the corresponding reaction mechanisms have been thoroughly revealed.It is sincerely expected that the in-depth discussion could give materials scientists certain inspiration to design brand-new dendritic mesoporous silica nanoparticles-based materials with superior capabilities towards CO_(2)capture,utilization,and storage.

科产教融合下“现代分析技术”课程改革与实践

本文在科产教融合理念下,对“现代分析技术”进行了课程改革。主要基于校内/际/企合作实现优质师资共享,通过融入科学前沿和生产实际丰富教学内容,在授课中采用教师主导、学生自主探究、“理虚实”结合、线上线下协同、公众号辅助等多维教学模式,同时配备多元化考核评价体系促学促教。实践结果表明,教学质量得到了明显提升,极大地助力于理论知识、科学研究、生产实践兼顾兼优的复合型人才的培养。

中华钝颊叶蜂种团评述暨中国三新种记述(膜翅目:叶蜂科)

记述中国中华钝颊叶蜂种团(膜翅目:叶蜂科)3新种:华北钝颊叶蜂A.huabei Li,Liu&Wei sp.nov.,宽带钝颊叶蜂A.latifasciatum Li,Liu&Wei sp.nov.和黑盾钝颊叶蜂A.nigroscutellare Li,Liu&Wei sp.nov.。主要讨论了中华钝颊叶蜂种团的鉴别特征。提供了中华钝颊叶蜂种团中国已知种分种检索表。

Accuracy of FreeStyle Libre flash glucose monitoring in patients with type 2 diabetes who migrated from highlands to plains

BACKGROUND The FreeStyle Libre flash glucose monitoring(FGM)system entered the Chinese market in 2017 to complement the self-monitoring of blood glucose.Due to its increased usage in clinics,the number of studies investigating its accuracy has increased.However,its accuracy has not been investigated in highland populations in China.AIM To evaluate measurements recorded using the FreeStyle Libre FGM system compared with capillary blood glucose measured using the enzyme electrode method in patients with type 2 diabetes(T2D)who had migrated within 3 mo from highlands to plains.METHODS Overall,68 patients with T2D,selected from those who had recently migrated from highlands to plains(within 3 mo),were hospitalized at the Department of Endocrinology from August to October 2017 and underwent continuous glucose monitoring(CGM)with the FreeStyle Libre FGM system for 14 d.Throughout the study period,fingertip capillary blood glucose was measured daily using the enzyme electrode method(Super GL,China),and blood glucose levels were read from the scanning probe during fasting and 2 h after all three meals.Moreover,the time interval between reading the data from the scanning probe and collecting fingertip capillary blood was controlled to<5 min.The accuracy of the FGM system was evaluated according to the CGM guidelines.Subsequently,the factors influencing the mean absolute relative difference(MARD)of this system were analyzed by a multiple linear regression method.RESULTS Pearson’s correlation analysis showed that the fingertip and scanned glucose levels were positively correlated(R=0.86,P=0.00).The aggregated MARD of scanned glucose was 14.28±13.40%.Parker's error analysis showed that 99.30%of the data pairs were located in areas A and B.According to the probe wear time of the FreeStyle Libre FGM system,MARD_(1 d) and MARD_(2-14 d) were 16.55%and 14.35%,respectively(t=1.23,P=0.22).Multiple stepwise regression analysis showed that MARD did not correlate with blood glucose when the largest amplitude of glycemic excursion(LAGE)was<5.80 mmol/L but negatively correlated with blood glucose when the LAGE was≥5.80 mmol/L.CONCLUSION The FreeStyle Libre FGM system has good accuracy in patients with T2D who had recently migrated from highlands to plains.This system might be ideal for avoiding the effects of high hematocrit on blood glucose monitoring in populations that recently migrated to plains.MARD is mainly influenced by glucose levels and fluctuations,and the accuracy of the system is higher when the blood glucose fluctuation is small.In case of higher blood glucose level fluctuations,deviation in the scanned glucose levels is the highest at extremely low blood glucose levels.

新冠疫情下中国国际航线网络演化特征

全球疫情形势下,各国国际航班政策变化、国际航线数量下降、国际客流量锐减对中国国际航线网络结构特征产生了重大影响,分析疫情下中国国际航线网络演化特征对于航空公司未来国际航线恢复和资源调配决策具有非常重要意义。采用K-Core网格划分算法对2019-2021年不同时期中国国际航线网络进行层级划分,通过分析各节点网络特征、所属层级和中转旅客份额等指标变化情况,确定节点和层级功能的转变,判断网络结构发展趋势。根据节点度、旅客运输量和感染人数对网络节点重要程度进行评估和排序,并通过依次移除节点的方式对网络进行蓄意攻击,分析不同层级网络的鲁棒性变化,识别疫情发展不同时期的关键节点。研究表明:在诸如旅客需求减少、国际航班政策等内外因素驱动下,国际航线网络结构和节点功能均发生改变,且部分改变是不可逆的,核心层与网络整体的连接性和主导作用逐步减弱,连接层的中转功能进一步加强,边缘层成为最具潜力的恢复市场。航空公司可以考虑与边缘层节点建立良好的连通关系,不仅可以维持突发情况下网络的正常运转,还可以在网络恢复期重建关键中转节点,提升国际客流份额。

Relationship of ultrasonic shear wave velocity with oncogene and tumor suppressor gene expression in primary liver cancer lesions as well as angiogenesis factor contents

Objective:To discuss the relationship of ultrasonic shear wave velocity (SWV) with oncogene and tumor suppressor gene expression in primary liver cancer lesions as well as angiogenesis factor contents.Methods:100 patients with primary liver cancer who underwent surgical treatment in our hospital between March 2014 and September 2016 were collected as observation group, and 50 healthy subjects who received physical examination in our hospital during the same period were collected as normal control group. The ultrasonic SWV levels of two groups of subjects were measured before the operation, and the observation groups were further divided into high SWV group and low SWV group, 50 cases in each group. Intraoperative tumor tissue samples were kept and fluorescence quantitative PCR was used to determine the mRNA expression of oncogenes and tumor suppressor genes. Enzyme-linked immunosorbent assay was used to determine serum contents of angiogenesis factors in observation group before operation.Results:Hepatic ultrasonic SWV level in observation group was significantly higher than that in normal control group;proto-oncogene CK, Ki67, Gly-3, Survivin and Pokemon mRNA expression in tumor tissue of high SWV group were higher than those of low SWV group while tumor suppressor genes Tg737, p16, p27, PTEN and runx3 mRNA expression were lower than those of low SWV group;serum angiogenesis factors VEGF, MMP-9 and IGF-1R contents were higher than those in low SWV group. Conclusion: The hepatic ultrasonic SWV level increases in patients with primary liver cancer, and the SWV level is directly correlated with oncogene and tumor suppressor gene expression as well as angiogenesis factor contents.

First application of plutonium in soil erosion research on terraces

The spatial distributions of ^(239+240)Pu and ^(137)Cs in soils from Longji Rice Terraces were investigated to evaluate soil erosion.The activity concentrations of ^(239+240)Pu and ^(137)Cs in the surface soils of the paddy fields were in the range of 0.089–0.734 and1.80–7.88 mBq/g,respectively.The activities of ^(239+240)Pu and ^(137)Cs showed very similar distribution trends,first increasing and then decreasing with increasing elevation.The 240Pu/239Pu atom ratios in the surface soils ranged from 0.162 to 0.232.The activities of ^(239+240)Pu and ^(137)Cs in the soil cores tended to be uniformly distributed within the plowed layer and declined exponentially below this depth.The mean soil erosion rates of Longji Rice Terraces estimated by ^(239+240)Pu and ^(137)Cs tracer methods were 5.44 t/(ha·a)and 5.16 t/(ha·a),respectively,which demonstrated that plutonium can replace ^(137)Cs as an ideal tracer for soil erosion research in the future.Landform features are the main factors affecting the distribution of plutonium and ^(137)Cs as well as soil erosion in the Longji Rice Terraces.

On testing proportional odds assumptions for proportional odds models

Proportional odds models are commonly used to model ordinal responses,but the proportional odds assumption may not hold in practice,leading to biased inference.Tests such as score,Wald and likelihood ratio(LR)have been proposed to evaluate the proportional odds assumption based on models without the assumption.Brant has proposed an independent binary model-based Wald-type test,and Wolfe and Gould have extended the idea to propose an LR-type test.This paper provides a brief review of the Brant and Wolfe-Gould tests for evaluating the proportional odds assumption and evaluates their performance through simulation studies and a real data example.Sample programs are provided in SAS,SPSS and Stata to facilitate the implementation of these tests using standard statistical software packages.This study highlights the importance of evaluating the proportional odds assumption when using proportional odds models for ordinal responses.The sample programs provided in this paper make it easy for researchers to apply these tests in their own analyses using standard statistical software packages.

低度近视青少年的脑视觉认知功能评估（英文）

目的:比较低度近视青少年与正常青少年的脑视觉认知功能,研究早期、低度近视对脑视觉认知功能的影响。方法:共120名青少年按屈光状态分为低度近视组、屈光参差组以及正常对照组。通过知觉眼位、注视稳定性和立体视来评估参与者的脑视觉认知功能。其中,立体视的检查包括经典远、近立体视(同视机、Titmus)和0.8m和1.5m的3D-随机点静态0阶立体视检查(简称3D立体视)。结果:1)知觉眼位:低度近视组水平知觉眼位显著偏移;屈光参差组水平、垂直知觉眼位均显著偏移;2)注视稳定性:低度近视组和屈光参差组注视稳定性降低;3)立体视:屈光参差组0.8m和1.5m立体视检查的正常率较其余两组降低。低度近视组1.5m 3D立体视正常率降低;4)注视稳定性与近立体视之间存在弱的正相关性。结论:低度近视即使在矫正至最佳矫正视力后,仍存在一定脑视觉认知功能的缺陷,研究还提示,除局部视网膜调控外,脑视觉中枢可能也参与了近视发生发展。

直肠癌患者腹腔镜手术中淋巴结检出数量的相关因素研究

目的探讨直肠癌腹腔镜手术淋巴结检出数量的相关因素。方法选取2014年1月-2017年1月于该院行腹腔镜下微创手术治疗的98例直肠癌患者为研究对象。统计患者一般资料[性别、年龄、体质指数(BMI)]、术前影像学检查结果、临床病理资料(肿瘤大小、大体类型、TNM分期、远处转移、组织分化程度和浸润深度等)、手术情况(术者、手术时间)和术前放化疗情况。结果年龄、BMI、肿瘤大小、标本长度、浸润深度、术者情况、术前放化疗与直肠癌微创手术患者淋巴结检出数量有关(P<0.05),而性别、TNM分期、大体类型、组织分化程度、手术时间与直肠癌微创手术患者淋巴结检出数量无关(P>0.05)。多元线性回归分析结果表明,BMI、肿瘤大小、标本长度、浸润深度、术者和术前放化疗是直肠癌微创手术患者淋巴结检出数量的独立影响因素(P<0.05)。结论患者因素、肿瘤状况、手术因素均及治疗情况与直肠癌微创手术淋巴结检出数量有关。

考虑碳排放的长三角机场运营效率研究

传统的机场运营效率研究忽视了非期望产出对机场运营效率的影响,且对有效单元无法进一步排名,基于此,采用长江三角洲16个机场2015~2019年的面板数据,将碳排放量和旅客投诉数量作为非期望产出指标,通过模型对比分析非期望产出的必要性,利用GML(Global Malmquist-Luenberger)指数刻画出机场全要素生产率的时空特性.结果表明,考虑非期望产出后,机场的静态运营效率和动态全要素生产率均产生变化.2015~2019年,长三角机场运营效率呈现波动上升,小型机场受非期望产出影响较大;2015~2019年,长三角机场全要素生产率受技术效率和技术进步共同影响,非期望产出影响技术进步上升的机场数量较多,但是对机场的技术效率影响更大.

数据分析中的对数转换和意义(英文)

对数转换的方法在生物医学和社会心理研究中处理非正态数据时被广泛应用。本文重点介绍该传统方法在处理非正态数据时存在的严重问题。尽管通常认为对数转换可以减少数据的变异性,使数据更符合正态分布,但是通常并非如此。此外,对数转换后的数据得出的标准统计测试结果往往和未转化的原始数据不相关。我们通过使用模拟数据示例来说明这些问题。我们认为如果采用数据转换,必须非常谨慎应用。我们建议研究者在大多数情况下摒弃这些处理非正态数据的传统方法,选择采用较新的不依赖于数据分布的方法:如广义估计方程(GEE)。

A Precise Calibration Method on Phase Center of Uplink Antenna Array Considering Its Actual Pointing

With regard to the inferior techniques and low accuracy of phase center calibration of an antenna array, this paper proposes a new calibration method considering the actual antenna pointing by introducing a precise engineering surveying technique to measure the real state of antennas. First, an industrial photogrammetric system is utilized to obtain the coordinates of points on antenna panels in different postures, and the actual pointing of the mechanical axis is obtained via least-squares fitting. Then, based on this, the coordinates of antenna rotation center are obtained by seeking the intersection of mechanical axes via using the matrix method. Finally, the mechanical axis in arbitrary postures is estimated based on the inverse-angle weighting interpolation method, and the reliable phase center is obtained by moving a fixed length from the projective center along the mechanical axis. An uplink antenna array including three ? 3 m antennas is taken as experimental object, and all photogrammetric coordinate systems are unified by the engineering control network, with each antenna phase center precisely calibrated via the proposed method. The results of electrical signal synthesis indicate that this method can effectively overcome the influence of gravity deformation and mechanical installation error, and enhance the synthetic signal magnitude of the uplink antenna array.

2型糖尿病患者服用二甲双胍影响血肌酐与乳酸的关系

目的探讨肾功正常的高原地区2型糖尿病患者服用二甲双胍后,对血肌酐与乳酸的关系是否产生影响。方法选择肾功能正常的2型糖尿病患者478例,按治疗方案分为A组和B组,A组(262例)是二甲双胍用药组,B组(216例)是二甲双胍未用药组。用酶电极法测定血乳酸水平,比较两组间血乳酸的差异,探讨两组中血肌酐与乳酸之间的关系。结果1、两组间平均血乳酸水平无统计学差异[(1.54±0.73 vs 1.48±0.54)mmol/L,p=0.368]。2、A组共有47例(17.9%)出现高乳酸血症,B组有33例(15.3%),两组间高乳酸血症的发审率无差异(p=0.407)。3、相关分析结果显示,在校正腰围、血红蛋白、年龄、BMI、糖尿病病程后,当A组中肌酐≤90μmol/L时,肌酐与乳酸之间的关系无统计学意义(P﹥0.05),而当肌酐≥91μmol/L时,乳酸水平随即升高(P<0.05);而B组中并未观察到肌酐与乳酸相关。结论肾功能正常的高原地区2型糖尿病患者应用二甲双胍时,需监测乳酸水平,当肌酐≥91μmol/L后,患者发生高乳酸血症的风险增加。

库区某污水处理厂提标改造设计

库区某污水处理厂提标改造工程设计建设规模为30000m^3/d。针对污水特点和提标要求,该工程处理工艺采用:A/A/O+MBR工艺,污泥处理采用机械浓缩脱水工艺,臭气采用生物过滤法工艺。详细介绍了进、出水水质及提标工艺流程、主要设计参数,出水水质最终满足《城镇污水处理厂污染物排放标准》(GB18918—2002)中的一级A标准,相关经验可供类似工程参考借鉴。

Effects of liraglutide combined with metformin on lipid metabolism and micro-inflammatory response in T2DM patients with obesity

Objective:To investigate the effects of liraglutide combined with metformin on lipid metabolism and micro-inflammatory response in T2DM patients with obesity.Methods:A total of 138 T2DM patients with obesity who were treated in the hospital between May 2016 and August 2017 were divided into control group (n=69) and liraglutide group (n=69) by random number table method. Control group received metformin therapy and liraglutide group received liraglutide combined with metformin therapy, which lasted for 3 months. The differences in the levels of insulin resistance indexes, cholesterol-related indexes, apolipoprotein and inflammatory mediators were compared between the two groups.Results:After 3 months of treatment, serum insulin resistance-related indexes FBG and FINS levels of liraglutide group were lower than those of control group;serum cholesterol-related indexes TC and LDL-C contents were lower than those of control group whereas HDL-C content was higher than that of control group;serum apolipoprotein Apo AⅠ and Apo AⅡ contents were higher than those of control group whereas Apo CⅡ and Apo CⅢ contents were lower than those of control group;serum inflammatory mediators IL-6, IL-17 and TNF-α contents were lower than those of control group.Conclusion:Metformin combined with liraglutide therapy can further optimize the glycolipid metabolism and inhibit the micro-inflammatory state in T2DM patients with obesity.

The aromatic peptide protected gold nanoclusters with significant Stokes shift:Ligand-mediated two-step FRET

During the last decade,a great variety of ligand protected gold nanoclusters(AuNCs)have been synthesized,and their broad applications have been intensively reported.Although the spectroscopic properties of AuNCs have been comprehensively explored,the mechanism of the significant Stokes shift(>200 nm)and the specific role played by surface ligands have not been clearly explained yet.In this study,a series of fluorescent AuNCs with huge Stokes shift(up to 530 nm)were successfully prepared by employing the rationally designed tri-peptides as the protecting ligands,and their spectroscopic properties were systematically investigated.The detailed measurements on the example product,YCY-AuNCs(Tyr-Cys-Tyr liganded AuNCs),showed that the energy absorbed by the tyrosine(~250 nm)can be effectively transferred through the ligand-mediated two-step Förster resonance energy transfer(FRET)process and released as fluorescence emission in the near-infrared fluorescence(NIR)range(~780 nm),which resulted in the significant apparent Stokes shift.The YCY ligands play a critical role by offering the tyrosine groups(donor of the first FRET pair),generating the dityrosine-like structure on the AuNCs surface(acceptor of the first FRET pair and donor of the second FRET pair),and protecting the cores(acceptor of the second acceptor).The additional ligand exchange experiments and the investigation on the other AuNCs further demonstrated that the sufficient high density of the aromatic groups is also essential to mediate the two-step FRET and achieve the remarkable Stokes shift.We believe that the aromatic ligand-mediated FRET mechanism not only offers a new theoretical explanation for the huge Stokes shift exhibited in AuNCs,but also provides a general strategy for the construction of new materials with large Stokes shift.