Nitrogen(N)deposition is a significant aspect of global change and poses a threat to terrestrial biodiversity.The impact of plant-soil microbe relationships to N deposition has recently attracted considerable attentio...Nitrogen(N)deposition is a significant aspect of global change and poses a threat to terrestrial biodiversity.The impact of plant-soil microbe relationships to N deposition has recently attracted considerable attention.Soil microorganisms have been proven to provide nutrients for specific plant growth,especially in nutrient-poor desert steppe ecosystems.However,the effects of N deposition on plant-soil microbial community interactions in such ecosystems remain poorly understood.To investigate these effects,we conducted a 6-year N-addition field experiment in a Stipa breviflora Griseb.desert steppe in Inner Mongolia Autonomous Region,China.Four N treatment levels(N0,N30,N50,and N100,corresponding to 0,30,50,and 100 kg N/(hm2•a),respectively)were applied to simulate atmospheric N deposition.The results showed that N deposition did not significantly affect the aboveground biomass of desert steppe plants.N deposition did not significantly reduce the alfa-diversity of plant and microbial communities in the desert steppe,and low and mediate N additions(N30 and N50)had a promoting effect on them.The variation pattern of plant Shannon index was consistent with that of the soil bacterial Chao1 index.N deposition significantly affected the beta-diversity of plants and soil bacteria,but did not significantly affect fungal communities.In conclusion,N deposition led to co-evolution between desert steppe plants and soil bacterial communities,while fungal communities exhibited strong stability and did not undergo significant changes.These findings help clarify atmospheric N deposition effects on the ecological health and function of the desert steppe.展开更多
In 2003,Xi Jinping,then secretary of the Zhejiang Provincial Committee of the Communist Party of China,launched the Green Rural Revival Programme aimed at renovating 10,000 administrative villages in the province and ...In 2003,Xi Jinping,then secretary of the Zhejiang Provincial Committee of the Communist Party of China,launched the Green Rural Revival Programme aimed at renovating 10,000 administrative villages in the province and turning a thousand key ones among them into all-round well-o!model villages.展开更多
目的 研究利那洛肽联合复方聚乙二醇(PEG)用于结肠镜前肠道准备的安全性和有效性。方法 选取2023年1月至6月于青岛大学附属医院消化内科行结肠镜检查的612例患者。采用随机数字表法将其分为1组(1 L PEG+2 L PEG组)、2组(利那洛肽+2 L PE...目的 研究利那洛肽联合复方聚乙二醇(PEG)用于结肠镜前肠道准备的安全性和有效性。方法 选取2023年1月至6月于青岛大学附属医院消化内科行结肠镜检查的612例患者。采用随机数字表法将其分为1组(1 L PEG+2 L PEG组)、2组(利那洛肽+2 L PEG组)和3组(1 L PEG+利那洛肽+1 L PEG组),每组各204例。比较各组渥太华评分(OBPS)、进镜时间、首次排便时间、排便次数、患者不良反应发生率和患者耐受性。结果 共601名患者按要求完成肠道准备及结肠镜检查。1组和2组OBPS和进镜时间差异无统计学意义。2组首次排便时间短于1组和3组(P<0.05)。1组排便次数多于2组和3组(P<0.05)。2组和3组不良反应发生率显著低于1组(P<0.05)。患者整体耐受性评分1组低于2组和3组(P<0.05)。结论 2 L PEG联合290μg利那洛肽用于结肠镜前肠道准备的效果与3 L PEG相似,且不良反应发生率低,患者耐受性好;对于1次性服用大剂量PEG不耐受的患者可考虑应用1 L PEG+利那洛肽+1 L PEG方案。展开更多
目的采用文献计量学的方法可视化分析干细胞在特发性肺纤维化(IPF)领域的相关文献,探讨该领域的研究热点和不足。方法在Web of Science核心集数据库检索2003—2022年收录的干细胞在IPF领域相关文献,通过VOSviewer 1.6.19和Citespace 6.2...目的采用文献计量学的方法可视化分析干细胞在特发性肺纤维化(IPF)领域的相关文献,探讨该领域的研究热点和不足。方法在Web of Science核心集数据库检索2003—2022年收录的干细胞在IPF领域相关文献,通过VOSviewer 1.6.19和Citespace 6.2.R4软件对文献进行年发文量、国家/地区、机构、作者、期刊分布等方面的分析。同时还进行关键词共现分析和文献共被引分析。结果共纳入文献637篇,此领域年发文量呈稳步增长态势,发文量最多的国家/地区是美国,发文量最多的机构是匹兹堡大学,发文量最多的作者有3位,分别是Geiser Thomas、Han Xiaodong和Rojas Mauricio,核心共被引作者是Noble Paul W,发表文献最多的期刊是American Journal of Respiratory and Critical Care Medicine。热点分析结果显示,2018年以来干细胞治疗IPF的研究热点主要集中在发病机制、间充质干细胞(MSCs)的治疗潜力以及新药研发等。结论干细胞在IPF领域的研究数量逐年增长;参与该领域研究的作者和机构众多,但高产作者和机构相对较少,因此需要加强不同作者、机构、地区及国家间的合作。热点分析结果显示干细胞治疗为IPF患者提供了一种很有前景的治疗方式,但临床应用中仍有一些问题亟须解决,例如确定干细胞的最佳来源、干细胞移植途径、干细胞移植次数和时间以及适当的干细胞移植间隔等以评估干细胞治疗IPF的可行性。展开更多
基金the National Natural Science Foundation of China(31860136,31560156)the Basic Scientific Research Service Fee Project of Colleges and Universities of Inner Mongolia Autonomous Regionthe Graduate Scientific Research Innovation Project of Inner Mongolia Autonomous Region(B20210158Z).
文摘Nitrogen(N)deposition is a significant aspect of global change and poses a threat to terrestrial biodiversity.The impact of plant-soil microbe relationships to N deposition has recently attracted considerable attention.Soil microorganisms have been proven to provide nutrients for specific plant growth,especially in nutrient-poor desert steppe ecosystems.However,the effects of N deposition on plant-soil microbial community interactions in such ecosystems remain poorly understood.To investigate these effects,we conducted a 6-year N-addition field experiment in a Stipa breviflora Griseb.desert steppe in Inner Mongolia Autonomous Region,China.Four N treatment levels(N0,N30,N50,and N100,corresponding to 0,30,50,and 100 kg N/(hm2•a),respectively)were applied to simulate atmospheric N deposition.The results showed that N deposition did not significantly affect the aboveground biomass of desert steppe plants.N deposition did not significantly reduce the alfa-diversity of plant and microbial communities in the desert steppe,and low and mediate N additions(N30 and N50)had a promoting effect on them.The variation pattern of plant Shannon index was consistent with that of the soil bacterial Chao1 index.N deposition significantly affected the beta-diversity of plants and soil bacteria,but did not significantly affect fungal communities.In conclusion,N deposition led to co-evolution between desert steppe plants and soil bacterial communities,while fungal communities exhibited strong stability and did not undergo significant changes.These findings help clarify atmospheric N deposition effects on the ecological health and function of the desert steppe.
文摘In 2003,Xi Jinping,then secretary of the Zhejiang Provincial Committee of the Communist Party of China,launched the Green Rural Revival Programme aimed at renovating 10,000 administrative villages in the province and turning a thousand key ones among them into all-round well-o!model villages.
文摘目的 研究利那洛肽联合复方聚乙二醇(PEG)用于结肠镜前肠道准备的安全性和有效性。方法 选取2023年1月至6月于青岛大学附属医院消化内科行结肠镜检查的612例患者。采用随机数字表法将其分为1组(1 L PEG+2 L PEG组)、2组(利那洛肽+2 L PEG组)和3组(1 L PEG+利那洛肽+1 L PEG组),每组各204例。比较各组渥太华评分(OBPS)、进镜时间、首次排便时间、排便次数、患者不良反应发生率和患者耐受性。结果 共601名患者按要求完成肠道准备及结肠镜检查。1组和2组OBPS和进镜时间差异无统计学意义。2组首次排便时间短于1组和3组(P<0.05)。1组排便次数多于2组和3组(P<0.05)。2组和3组不良反应发生率显著低于1组(P<0.05)。患者整体耐受性评分1组低于2组和3组(P<0.05)。结论 2 L PEG联合290μg利那洛肽用于结肠镜前肠道准备的效果与3 L PEG相似,且不良反应发生率低,患者耐受性好;对于1次性服用大剂量PEG不耐受的患者可考虑应用1 L PEG+利那洛肽+1 L PEG方案。
文摘目的采用文献计量学的方法可视化分析干细胞在特发性肺纤维化(IPF)领域的相关文献,探讨该领域的研究热点和不足。方法在Web of Science核心集数据库检索2003—2022年收录的干细胞在IPF领域相关文献,通过VOSviewer 1.6.19和Citespace 6.2.R4软件对文献进行年发文量、国家/地区、机构、作者、期刊分布等方面的分析。同时还进行关键词共现分析和文献共被引分析。结果共纳入文献637篇,此领域年发文量呈稳步增长态势,发文量最多的国家/地区是美国,发文量最多的机构是匹兹堡大学,发文量最多的作者有3位,分别是Geiser Thomas、Han Xiaodong和Rojas Mauricio,核心共被引作者是Noble Paul W,发表文献最多的期刊是American Journal of Respiratory and Critical Care Medicine。热点分析结果显示,2018年以来干细胞治疗IPF的研究热点主要集中在发病机制、间充质干细胞(MSCs)的治疗潜力以及新药研发等。结论干细胞在IPF领域的研究数量逐年增长;参与该领域研究的作者和机构众多,但高产作者和机构相对较少,因此需要加强不同作者、机构、地区及国家间的合作。热点分析结果显示干细胞治疗为IPF患者提供了一种很有前景的治疗方式,但临床应用中仍有一些问题亟须解决,例如确定干细胞的最佳来源、干细胞移植途径、干细胞移植次数和时间以及适当的干细胞移植间隔等以评估干细胞治疗IPF的可行性。
