Background The relationships between dietary intake of soybean products and incident hypertension were still uncertain.This study aimed to illustrate the associations between intake of soybean products with risks of i...Background The relationships between dietary intake of soybean products and incident hypertension were still uncertain.This study aimed to illustrate the associations between intake of soybean products with risks of incident hypertension and longitudinal changes of blood pressure in a prospective cohort study.Methods We included 67,499 general Chinese adults from the Project of Prediction for Atherosclerosis Cardiovascular Disease Risk in China(China-PAR).Information about soybean products consumption was collected by standardized questionnaires,and study participants were categorized into the ideal(≥125 g/day)or non-ideal(<125 g/day)group.Hazard ratios(HRs)and corresponding 95%confidence intervals(95%CIs)for incident hypertension were calculated using Cox proportional hazard models.Among participants with repeated measures of blood pressure,generalized linear models were used to examine the relationships between soybean products consumption and blood pressure changes.Results During a median follow-up of 7.4 years,compared with participants who consumed<125 g of soybean products per day,multivariable adjusted HR for those in the ideal group was 0.73(0.67-0.80).This inverse association remained robust across most subgroups while significant interactions were tested between soybean products intake and age,sex,urbanization and geographic region(P values for interaction<0.05).The mean systolic and diastolic blood pressure levels were 1.05(0.71-1.39)mmHg and 0.44(0.22-0.66)mmHg lower among participants in the ideal group than those in the non-ideal group.Conclusions Our study showed that intake of soybean products might reduce the long-term blood pressure levels and hypertension incidence among Chinese population,which has important public health implications for primary prevention of hypertension.展开更多
The earliest use of Lycium barbarum L.(Goji fruits)as a medicinal plant was at around 2,300 years ago,and nowadays it is used as a medicinal food(Figure 1)[1,2].There have been some reports on the antifertility effect...The earliest use of Lycium barbarum L.(Goji fruits)as a medicinal plant was at around 2,300 years ago,and nowadays it is used as a medicinal food(Figure 1)[1,2].There have been some reports on the antifertility effects and fertility-promoting or aphrodisiac effects[3-5].The famous Chinese herbalist Li Shizhen first recorded the pro-fertility efficacy of Lycium barbarum L.in Compendium of Materia Medica in the 16th century[6].Lycium barbarum L.also has many other effects,such as the antioxidant function,anti-cytotoxicity,anti-fatty acid toxicity,neuroprotective and anticancer effects,and so on[7].Lycium barbarum L.is rich in vitamins,zeaxanthin,carotenoid and other ingredients[8].展开更多
基金Supported by the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2017-I2M-1-004,2019-I2M-2-003)National Key Research&Development Program of China(2017YFC0211700)National Natural Science Foundation of China(91843302).The authors declared no conflicts of interest.
文摘Background The relationships between dietary intake of soybean products and incident hypertension were still uncertain.This study aimed to illustrate the associations between intake of soybean products with risks of incident hypertension and longitudinal changes of blood pressure in a prospective cohort study.Methods We included 67,499 general Chinese adults from the Project of Prediction for Atherosclerosis Cardiovascular Disease Risk in China(China-PAR).Information about soybean products consumption was collected by standardized questionnaires,and study participants were categorized into the ideal(≥125 g/day)or non-ideal(<125 g/day)group.Hazard ratios(HRs)and corresponding 95%confidence intervals(95%CIs)for incident hypertension were calculated using Cox proportional hazard models.Among participants with repeated measures of blood pressure,generalized linear models were used to examine the relationships between soybean products consumption and blood pressure changes.Results During a median follow-up of 7.4 years,compared with participants who consumed<125 g of soybean products per day,multivariable adjusted HR for those in the ideal group was 0.73(0.67-0.80).This inverse association remained robust across most subgroups while significant interactions were tested between soybean products intake and age,sex,urbanization and geographic region(P values for interaction<0.05).The mean systolic and diastolic blood pressure levels were 1.05(0.71-1.39)mmHg and 0.44(0.22-0.66)mmHg lower among participants in the ideal group than those in the non-ideal group.Conclusions Our study showed that intake of soybean products might reduce the long-term blood pressure levels and hypertension incidence among Chinese population,which has important public health implications for primary prevention of hypertension.
文摘The earliest use of Lycium barbarum L.(Goji fruits)as a medicinal plant was at around 2,300 years ago,and nowadays it is used as a medicinal food(Figure 1)[1,2].There have been some reports on the antifertility effects and fertility-promoting or aphrodisiac effects[3-5].The famous Chinese herbalist Li Shizhen first recorded the pro-fertility efficacy of Lycium barbarum L.in Compendium of Materia Medica in the 16th century[6].Lycium barbarum L.also has many other effects,such as the antioxidant function,anti-cytotoxicity,anti-fatty acid toxicity,neuroprotective and anticancer effects,and so on[7].Lycium barbarum L.is rich in vitamins,zeaxanthin,carotenoid and other ingredients[8].
