This study proposes a convolutional neural network(CNN)-based identity recognition scheme using electrocardiogram(ECG)at different water temperatures(WTs)during bathing,aiming to explore the impact of ECG length on th...This study proposes a convolutional neural network(CNN)-based identity recognition scheme using electrocardiogram(ECG)at different water temperatures(WTs)during bathing,aiming to explore the impact of ECG length on the recognition rate.ECG data was collected using non-contact electrodes at five different WTs during bathing.Ten young student subjects(seven men and three women)participated in data collection.Three ECG recordings were collected at each preset bathtub WT for each subject.Each recording is 18 min long,with a sampling rate of 200 Hz.In total,150 ECG recordings and 150 WT recordings were collected.The R peaks were detected based on the processed ECG(baseline wandering eliminated,50-Hz hum removed,ECG smoothing and ECG normalization)and the QRS complex waves were segmented.These segmented waves were then transformed into binary images,which served as the datasets.For each subject,the training,validation,and test data were taken from the first,second,and third ECG recordings,respectively.The number of training and validation images was 84297 and 83734,respectively.In the test stage,the preliminary classification results were obtained using the trained CNN model,and the finer classification results were determined using the majority vote method based on the preliminary results.The validation rate was 98.71%.The recognition rates were 95.00%and 98.00%when the number of test heartbeats was 7 and 17,respectively,for each subject.展开更多
Objective: To determine the clinicopathological characteristics, and evaluate the appropriate extent of lymph node dissection in distal gastric cancer patients with comparable T category. Methods: A retrospective st...Objective: To determine the clinicopathological characteristics, and evaluate the appropriate extent of lymph node dissection in distal gastric cancer patients with comparable T category. Methods: A retrospective study was conducted on 570 distal gastric cancer patients, who underwent gastric resection with D2 nodal dissection, which was performed by the same surgical team from January 1997 to January 2011. We compared the differences in lymph node metastasis rates and metastatic lymph node ratios between different T categories. Additionally, we investigated the impact of lymph node metastasis in the 7th station on survival rate of distal gastric cancer patients with the same TNM staging. Results: Among the 570 patients, the overall lymph node metastasis rate of advanced distal gastric cancer was 78.1%, and the metastatic lymph node ratio was 27%. The lymph node metastasis rate in the 7th station was similar to that of perigastric lymph nodes. There was no statistical significance in patients with the same TNM stage (stage Ⅱ and Ⅲ), irrespective of the metastatic status in the 7th station. Conclusions: Our results suggest that to a certain extent, it is reasonable to include lymph nodes in the 7th station in the D 1 lymph node dissection.展开更多
Wireless Body Area Networks(WBANs)refer to small sensor network that consists of sensor devices mounted on the surface of the body or implanted in the body,as such networks are employed to harvest physiological data o...Wireless Body Area Networks(WBANs)refer to small sensor network that consists of sensor devices mounted on the surface of the body or implanted in the body,as such networks are employed to harvest physiological data of the human body or to act as an assistant regulator of several specific physiological indicators of the human body.The sensor devices transmit the harvested human physiological data to the local node via a public channel.Before transmitting data,the sensor device and the local node should perform mutual authentication and key agreement.It is proposed in this paper a secure mutual authentication scheme of blockchain-based in WBANs.To analyze the security of this scheme,formal security analysis,and informal security analysis are used,then the computation and communication costs are compared with those of the relevant schemes.Relevant experimental results reveal that the proposed scheme exhibit more effective control over energy consumption and promising.展开更多
Please WBANs are a sensor network for detection and collection of sensitive data to the human body,which is lightweight and mobile.WBANs transmit sensitive and significant messages through the public channel,which mak...Please WBANs are a sensor network for detection and collection of sensitive data to the human body,which is lightweight and mobile.WBANs transmit sensitive and significant messages through the public channel,which makes it easy for an attacker to eavesdrop and modify the messages,thus posing a severe threat to the security of the messages.Therefore,it is essential to put in place authentication and key agreement between different communication nodes in WBANs.In this paper,a lightweight and secure authenticated key agreement protocol in wireless body area networks is designed.It is capable to reduce the cost of sensor node computation while ensuring security.Besides,an informal security analysis is conducted to discuss the security of the protocol against well-known attacks.Finally,the energy consumption of the protocol is evaluated,and the results show that the sensor nodes only need low storage cost,computational cost and communication cost.展开更多
Density functional theory calculations and ab initio molecular dynamics simulations are performed to study the feasibility of using borophene, a newly synthesized two-dimensional sheet of boron, as an anode material f...Density functional theory calculations and ab initio molecular dynamics simulations are performed to study the feasibility of using borophene, a newly synthesized two-dimensional sheet of boron, as an anode material for sodium-ion and sodium-oxygen batteries. The theo- retical capacity of borophene is found to be as high as 1,218 mAh g-1 (Nao.sB). More importantly, it is demonstrated that the sodium diffusion energy barrier along the valley direction is as low as 0.0019 eV, which corresponds to a diffusivity of more than a thousand times higher than that of conventional anode materials such as Na2Ti307 and Na3Sb. Hence, the use of borophene will revolutionize the rate capability of sodium-based batteries. Moreover, it is predicted that, during the sodiation process, the average open-circuit voltage is 0.53 V, which can effectively sup- press the formation of dendrites while maximizing the energy density. The metallic feature and structural integrity of borophene can be well preserved at different sodium concentrations, demonstrating good electronic conductivity and stable cyclability.展开更多
We propose a novel concept of energy storage that incorporates electrically rechargeable liquid fuels made of electroactive species, known as e-fuels, as the storage medium. This e-fuel energy storage system comprises...We propose a novel concept of energy storage that incorporates electrically rechargeable liquid fuels made of electroactive species, known as e-fuels, as the storage medium. This e-fuel energy storage system comprises an e-fuel charger and an e-fuel cell. The e-fuel charger electrically charges e-fuels, while the efuel cell subsequently generates electricity using charged e-fuels whenever and wherever on demand.The e-fuel energy storage system possesses all the advantages of conventional hydrogen storage systems,but unlike hydrogen, liquid e-fuels are as easy and safe to store and transport as gasoline. The potential efuel candidates have been identified to include inorganic electroactive materials, organic electroactive materials, and suspension of solid electroactive materials. In this work, we demonstrate an example efuel energy storage system for large-scale energy storage using inorganic e-fuels composed of V^(2+)/V^(3+) and VO_2^+/VO_2^+ redox couples, and compare the performance of the e-fuel energy storage system with that of existing technologies. Results show that our e-fuel charger achieves a charge efficiency of as high as~94%, while the e-fuel cell is capable of delivering a peak power density of 3.4 W cm^(-2), which is 1.7 times higher than that of hydrogen fuel cells. More excitingly, the e-fuel energy storage system exhibits a round-trip efficiency of 80.0% and an electrolyte utilization of 83.0% at an ultra-high discharge current density of 1,000 mA cm^(-2), which are 19.9% and 67.3% higher than those of conventional vanadium redox flow batteries. This unprecedented performance allows a 27.0% reduction in the capital cost of the e-fuel energy storage system compared with that of vanadium redox flow batteries.展开更多
The present study provides supportive evid-ence for the effective prevention and treatment of lipopo-lysaccharide(LPS)-induced hepatocyte injury in neonatal mice by N-acetylcysteine(NAC).Hepatocytes of neonatal mice w...The present study provides supportive evid-ence for the effective prevention and treatment of lipopo-lysaccharide(LPS)-induced hepatocyte injury in neonatal mice by N-acetylcysteine(NAC).Hepatocytes of neonatal mice were obtained through collagenase digestion of the liver.The hepatocytes were treated either with LPS(10 mg/mL)alone or with NAC(5 mmol/L)for 1 h before the addition of LPS(10 mg/mL).After LPS treatment,12 wells of the cultured hepatocytes and supernatants were harvested at 0,6,and 12 h,respectively.Levels of alanine aminotransferase(ALT)and nitric oxide(NO)in the supernatant were biochemically quantified and reverse transcription-polymerase chain reaction(RT-PCR)was performed to detect the expression of inducible nitric oxide synthase(iNOS)mRNA after different treatments.At 0 h following the treatment of primary cultured hepa-tocytes with LPS,the levels of ALT,NO and iNOS mRNA in the supernatant were(21.1±4.78)u/L,(1.6±0.31)mmol/L and 0.17±0.023,respectively;at 6 h,(59.8±8.59)u/L,(6.6±0.81)mmol/L,and 0.71±0.091;and at 12 h,(89.6±15.30)u/L,(7.8±1.01)mmol/L,and 0.71±0.097.The levels of ALT,NO and iNOS mRNA at 6 and 12 h increased significantly,compared to those at 0 h(P<0.01).In contrast to LPS treatment alone,pre-treatment with NAC before LPS addition significantly reduced the levels of ALT,NO and iNOS mRNA in the supernatant at 6 h to(40.8±7.30)u/L,(3.2±0.71)mmol/L,and 0.41±0.060;and at 12 h to(55.4±5.48)u/L,(4.0±0.71)mmol/L,and 0.40¡0.067,respectively(P<0.01).However,the levels of ALT,NO and iNOS mRNA at 0 h did not change significantly with both treat-ment approaches.NAC has protective effects in hepato-cytes of neonatal mice against LPS-induced injury as shown by the reduced levels of ALT,NO and iNOS mRNA when primary hepatocytes were treated with NAC prior to LPS stimulation.We postulate that NAC exhibits its protective function by inhibiting LPS-induced transcription of iNOS,resulting in decreased levels of NO.展开更多
基金This study is supported in part by the University of Aizu’s Competitive Research Fund(2020-P-24)。
文摘This study proposes a convolutional neural network(CNN)-based identity recognition scheme using electrocardiogram(ECG)at different water temperatures(WTs)during bathing,aiming to explore the impact of ECG length on the recognition rate.ECG data was collected using non-contact electrodes at five different WTs during bathing.Ten young student subjects(seven men and three women)participated in data collection.Three ECG recordings were collected at each preset bathtub WT for each subject.Each recording is 18 min long,with a sampling rate of 200 Hz.In total,150 ECG recordings and 150 WT recordings were collected.The R peaks were detected based on the processed ECG(baseline wandering eliminated,50-Hz hum removed,ECG smoothing and ECG normalization)and the QRS complex waves were segmented.These segmented waves were then transformed into binary images,which served as the datasets.For each subject,the training,validation,and test data were taken from the first,second,and third ECG recordings,respectively.The number of training and validation images was 84297 and 83734,respectively.In the test stage,the preliminary classification results were obtained using the trained CNN model,and the finer classification results were determined using the majority vote method based on the preliminary results.The validation rate was 98.71%.The recognition rates were 95.00%and 98.00%when the number of test heartbeats was 7 and 17,respectively,for each subject.
文摘Objective: To determine the clinicopathological characteristics, and evaluate the appropriate extent of lymph node dissection in distal gastric cancer patients with comparable T category. Methods: A retrospective study was conducted on 570 distal gastric cancer patients, who underwent gastric resection with D2 nodal dissection, which was performed by the same surgical team from January 1997 to January 2011. We compared the differences in lymph node metastasis rates and metastatic lymph node ratios between different T categories. Additionally, we investigated the impact of lymph node metastasis in the 7th station on survival rate of distal gastric cancer patients with the same TNM staging. Results: Among the 570 patients, the overall lymph node metastasis rate of advanced distal gastric cancer was 78.1%, and the metastatic lymph node ratio was 27%. The lymph node metastasis rate in the 7th station was similar to that of perigastric lymph nodes. There was no statistical significance in patients with the same TNM stage (stage Ⅱ and Ⅲ), irrespective of the metastatic status in the 7th station. Conclusions: Our results suggest that to a certain extent, it is reasonable to include lymph nodes in the 7th station in the D 1 lymph node dissection.
基金supported by the National Natural Science Foundation of China(Grant Nos.61872138&61572188)。
文摘Wireless Body Area Networks(WBANs)refer to small sensor network that consists of sensor devices mounted on the surface of the body or implanted in the body,as such networks are employed to harvest physiological data of the human body or to act as an assistant regulator of several specific physiological indicators of the human body.The sensor devices transmit the harvested human physiological data to the local node via a public channel.Before transmitting data,the sensor device and the local node should perform mutual authentication and key agreement.It is proposed in this paper a secure mutual authentication scheme of blockchain-based in WBANs.To analyze the security of this scheme,formal security analysis,and informal security analysis are used,then the computation and communication costs are compared with those of the relevant schemes.Relevant experimental results reveal that the proposed scheme exhibit more effective control over energy consumption and promising.
基金supported by the National Natural Science Foundation of China(Grant No.61872138).
文摘Please WBANs are a sensor network for detection and collection of sensitive data to the human body,which is lightweight and mobile.WBANs transmit sensitive and significant messages through the public channel,which makes it easy for an attacker to eavesdrop and modify the messages,thus posing a severe threat to the security of the messages.Therefore,it is essential to put in place authentication and key agreement between different communication nodes in WBANs.In this paper,a lightweight and secure authenticated key agreement protocol in wireless body area networks is designed.It is capable to reduce the cost of sensor node computation while ensuring security.Besides,an informal security analysis is conducted to discuss the security of the protocol against well-known attacks.Finally,the energy consumption of the protocol is evaluated,and the results show that the sensor nodes only need low storage cost,computational cost and communication cost.
基金supported by a Grant from the Research Grants Council of the Hong Kong Special Administrative Region,China(16213414)
文摘Density functional theory calculations and ab initio molecular dynamics simulations are performed to study the feasibility of using borophene, a newly synthesized two-dimensional sheet of boron, as an anode material for sodium-ion and sodium-oxygen batteries. The theo- retical capacity of borophene is found to be as high as 1,218 mAh g-1 (Nao.sB). More importantly, it is demonstrated that the sodium diffusion energy barrier along the valley direction is as low as 0.0019 eV, which corresponds to a diffusivity of more than a thousand times higher than that of conventional anode materials such as Na2Ti307 and Na3Sb. Hence, the use of borophene will revolutionize the rate capability of sodium-based batteries. Moreover, it is predicted that, during the sodiation process, the average open-circuit voltage is 0.53 V, which can effectively sup- press the formation of dendrites while maximizing the energy density. The metallic feature and structural integrity of borophene can be well preserved at different sodium concentrations, demonstrating good electronic conductivity and stable cyclability.
基金fully supported by the Grant from the Research Grant Council of the Hong Kong Special Administrative Region, China (T23-601/17-R)
文摘We propose a novel concept of energy storage that incorporates electrically rechargeable liquid fuels made of electroactive species, known as e-fuels, as the storage medium. This e-fuel energy storage system comprises an e-fuel charger and an e-fuel cell. The e-fuel charger electrically charges e-fuels, while the efuel cell subsequently generates electricity using charged e-fuels whenever and wherever on demand.The e-fuel energy storage system possesses all the advantages of conventional hydrogen storage systems,but unlike hydrogen, liquid e-fuels are as easy and safe to store and transport as gasoline. The potential efuel candidates have been identified to include inorganic electroactive materials, organic electroactive materials, and suspension of solid electroactive materials. In this work, we demonstrate an example efuel energy storage system for large-scale energy storage using inorganic e-fuels composed of V^(2+)/V^(3+) and VO_2^+/VO_2^+ redox couples, and compare the performance of the e-fuel energy storage system with that of existing technologies. Results show that our e-fuel charger achieves a charge efficiency of as high as~94%, while the e-fuel cell is capable of delivering a peak power density of 3.4 W cm^(-2), which is 1.7 times higher than that of hydrogen fuel cells. More excitingly, the e-fuel energy storage system exhibits a round-trip efficiency of 80.0% and an electrolyte utilization of 83.0% at an ultra-high discharge current density of 1,000 mA cm^(-2), which are 19.9% and 67.3% higher than those of conventional vanadium redox flow batteries. This unprecedented performance allows a 27.0% reduction in the capital cost of the e-fuel energy storage system compared with that of vanadium redox flow batteries.
文摘The present study provides supportive evid-ence for the effective prevention and treatment of lipopo-lysaccharide(LPS)-induced hepatocyte injury in neonatal mice by N-acetylcysteine(NAC).Hepatocytes of neonatal mice were obtained through collagenase digestion of the liver.The hepatocytes were treated either with LPS(10 mg/mL)alone or with NAC(5 mmol/L)for 1 h before the addition of LPS(10 mg/mL).After LPS treatment,12 wells of the cultured hepatocytes and supernatants were harvested at 0,6,and 12 h,respectively.Levels of alanine aminotransferase(ALT)and nitric oxide(NO)in the supernatant were biochemically quantified and reverse transcription-polymerase chain reaction(RT-PCR)was performed to detect the expression of inducible nitric oxide synthase(iNOS)mRNA after different treatments.At 0 h following the treatment of primary cultured hepa-tocytes with LPS,the levels of ALT,NO and iNOS mRNA in the supernatant were(21.1±4.78)u/L,(1.6±0.31)mmol/L and 0.17±0.023,respectively;at 6 h,(59.8±8.59)u/L,(6.6±0.81)mmol/L,and 0.71±0.091;and at 12 h,(89.6±15.30)u/L,(7.8±1.01)mmol/L,and 0.71±0.097.The levels of ALT,NO and iNOS mRNA at 6 and 12 h increased significantly,compared to those at 0 h(P<0.01).In contrast to LPS treatment alone,pre-treatment with NAC before LPS addition significantly reduced the levels of ALT,NO and iNOS mRNA in the supernatant at 6 h to(40.8±7.30)u/L,(3.2±0.71)mmol/L,and 0.41±0.060;and at 12 h to(55.4±5.48)u/L,(4.0±0.71)mmol/L,and 0.40¡0.067,respectively(P<0.01).However,the levels of ALT,NO and iNOS mRNA at 0 h did not change significantly with both treat-ment approaches.NAC has protective effects in hepato-cytes of neonatal mice against LPS-induced injury as shown by the reduced levels of ALT,NO and iNOS mRNA when primary hepatocytes were treated with NAC prior to LPS stimulation.We postulate that NAC exhibits its protective function by inhibiting LPS-induced transcription of iNOS,resulting in decreased levels of NO.