Ruxolitinib improves the inflammatory microenvironment,restores glutamate homeostasis,and promotes functional recovery after spinal cord injury

The inflammatory microenvironment and neurotoxicity can hinder neuronal regeneration and functional recovery after spinal cord injury.Ruxolitinib,a JAK-STAT inhibitor,exhibits effectiveness in autoimmune diseases,arthritis,and managing inflammatory cytokine storms.Although studies have shown the neuroprotective potential of ruxolitinib in neurological trauma,the exact mechanism by which it enhances functional recovery after spinal cord injury,particularly its effect on astrocytes,remains unclear.To address this gap,we established a mouse model of T10 spinal cord contusion and found that ruxolitinib effectively improved hindlimb motor function and reduced the area of spinal cord injury.Transcriptome sequencing analysis showed that ruxolitinib alleviated inflammation and immune response after spinal cord injury,restored EAAT2 expression,reduced glutamate levels,and alleviated excitatory toxicity.Furthermore,ruxolitinib inhibited the phosphorylation of JAK2 and STAT3 in the injured spinal cord and decreased the phosphorylation level of nuclear factor kappa-B and the expression of inflammatory factors interleukin-1β,interleukin-6,and tumor necrosis factor-α.Additionally,in glutamate-induced excitotoxicity astrocytes,ruxolitinib restored EAAT2 expression and increased glutamate uptake by inhibiting the activation of STAT3,thereby reducing glutamate-induced neurotoxicity,calcium influx,oxidative stress,and cell apoptosis,and increasing the complexity of dendritic branching.Collectively,these results indicate that ruxolitinib restores glutamate homeostasis by rescuing the expression of EAAT2 in astrocytes,reduces neurotoxicity,and effectively alleviates inflammatory and immune responses after spinal cord injury,thereby promoting functional recovery after spinal cord injury.

Awake rabbit model of ischemic spinal cord injury with delayed paraplegia:The role of ambient temperature

Background:Paraplegia after spinal cord ischemia is a devastating condition in the clinic.Here,we develop an awake rabbit model of spinal cord ischemia with delayed paraplegia and explore the influence of ambient temperature on the outcomes after injury.Methods:A total of 47 male rabbits were involved in the present study.Transient spinal cord ischemia was induced by occluding the infrarenal abdominal aorta of awake rabbits at different ambient temperatures.To find the optimal conditions for developing delayed paraplegia,hindlimb motor function after ischemia was evaluated between experiments.Results:The onset and magnitude of ischemic injury varied with the ambient temperature maintained during the peri-i schemia period.More serious spinal cord injury occurred when ischemia was induced at higher temperatures.At 18°C,25-minute ischemia resulted in 74%of rabbits developing delayed paraplegia.At a temperature of 28°C or higher,most of the animals developed acute paraplegia immediately.While at 13°C,rabbits usually regained normal motor function without paraplegia.Conclusion:This awake rabbit model is highly reproducible and will be helpful in future studies of delayed paraplegia after spinal cord ischemia.The ambient temperature must be considered while using this model during investigation of therapeutic interventions.

Alleviative effects of Bacillus coagulans strains on irritable bowel syndrome-unraveling strain specificity through physiological and genomic analysis

The high intraspecies heterogeneity of Baciillus coagulans leads to significant phenotypic differences among different strains.Thus,6 B.coagulans strains were tested in the present study using an irritable bowel syndrome(IBS)animal model to determine whether the IBS-alleviating effects of B.coagulans strains are strain-specific.The results of this study showed that the ingestion of B.coagulans GBI-30,6086,and B.coagulans CCFM1041 significantly alleviated IBS symptoms in mice.In contrast,other B.coagulans strains showed no or limited alleviating effects on IBS symptoms.According to our experimental results,the two main common features of these strains were as follows:1)The resistance of vegetative cells to bile salts,and 2)ability to synthesize specific lipids and secondary metabolites.Screening strains based on these two indicators may greatly reduce costs and provide a basis for mining new functional B.coagulans strains.Our results also suggest that administration of B.coagulans could significantly regulate microbiota dysbiosis in animal models.Moreover,the close relationships between the gut microbiota,gut microbiota metabolites,and IBS were further confirmed in this study.

Immunosuppressive tumor microenvironment in gastric signet-ring cell carcinoma

Gastric signet-ring cell carcinoma(GSRCC)is a subtype of gastric cancer with distinct phenotype and high risk of peritoneal metastasis.Studies have shown that early GSRCC has a good prognosis,while advanced GSRCC is insensitive to radiotherapy,chemotherapy or immune checkpoint blockade therapy.With technological advancement of single-cell RNA sequencing analysis and cytometry by time of flight mass cytometry,more detailed atlas of tumor microenvironment(TME)in GSRCC and its association with prognosis could be investigated extensively.Recently,two single-cell RNA sequencing studies revealed that GSRCC harbored a unique TME,manifested as highly immunosuppressive,leading to high immune escape.The TME of advanced GSRCC was enriched for immunosuppressive factors,including the loss of CXCL13+-cluster of differentiation 8+-Tex cells and declined clonal crosstalk among populations of T and B cells.In addition,GSRCC was mainly infiltrated by follicular B cells.The increased proportion of SRCC was accompanied by a decrease in mucosaassociated lymphoid tissue-derived B cells and a significant increase in follicular B cells,which may be one of the reasons for the poor prognosis of GSRCC.By understanding the relationship between immunosuppressive TME and poor prognosis in GSRCC and the underlying mechanism,more effective immunotherapy strategies and improved treatment outcomes of GSRCC can be anticipated.

Extradural contralateral S1 nerve root transfer for spastic lower limb paralysis

The current study aims to ascertain the anatomical feasibility of transferring the contralateral S1 ventral root(VR)to the ipsilateral L5 VR for treating unilateral spastic lower limb paralysis.Six formalin-fixed(three males and three females)cadavers were used.The VR of the contralateral S1 was transferred to the VR of the ipsilateral L5.The sural nerve was selected as a bridge between the donor and recipient nerve.The number of axons,the cross-sectional areas and the pertinent distances between the donor and recipient nerves were measured.The extradural S1 VR and L5 VR could be separated based on anatomical markers of the dorsal root ganglion.The gross distance between the S1 nerve root and L5 nerve root was 31.31(±3.23)mm in the six cadavers,while that on the diffusion tensor imaging was 47.51(±3.23)mm in 60 patients without spinal diseases,and both distances were seperately greater than that between the outlet of S1 from the spinal cord and the ganglion.The numbers of axons in the S1 VRs and L5 VRs were 13414.20(±2890.30)and 10613.20(±2135.58),respectively.The cross-sectional areas of the S1 VR and L5 VR were 1.68(±0.26)mm2 and 1.08(±0.26)mm2,respectively.In conclusion,transfer of the contralateral S1 VR to the ipsilateral L5 VR may be an anatomically feasible treatment option for unilateral spastic lower limb paralysis.

基于GCN-TextCNN的刑期预测模型

在建设法治社会的过程中,各类刑事案件层出不穷,现实也对刑事案件刑期判决的准确性和一致性提出了新的要求。而如今深度学习技术的发展让更多的模型有了助力现实生产生活的机会,有关的各类深度学习模型被引入到刑事案件上用于辅助司法从业人员对刑事案件的判决,现有的模型不能全面的提取刑事案件的文本特征,导致预测的准确率不高。为了提高准确率,文章提出了一种融合图卷积神经网络和卷积神经网络的刑期预测模型,在Cail2018数据集上对刑期预测问题有较好的效果。本文提出的模型用一定价值。

融合图卷积神经网络和BiGRU-TextCNN的罪名预测模型

随着人工智能的发展和司法信息化体系的构建,运用人工智能解决司法领域的需求成为近年来自然语言处理领域的研究热点.为了提升深度学习模型在罪名预测任务上的准确率,本文设想利用将图卷积神经网络提取文本之间的结构特征与传统的深度学习模型相融合,捕获更多潜在信息.因此本文提出了一种融合图卷积神经网络和BiGRU-TextCNN的罪名预测模型,实验结果表明在Cail2018数据集上对罪名预测问题有较好的效果.

Estrogen receptors in gastric cancer:Advances and perspectives

Worldwide, gastric cancer is one of the most common malignancies with high mortality. Various aspects of thedevelopment and progression of gastric cancer continue to be extensively investigated in order to further our understanding and provide more effective means for the prevention, diagnosis, and treatment of the disease. Estrogen receptors(ERs) are steroid hormone receptors that regulate cellular activities in many physiological and pathological processes in different tissues. There are two distinct forms of ERs, namely ERα and ERβ, with several alternative-splicing isoforms for each. They show distinct tissue distribution patterns and exert different biological functions. Dysregulation of ERs has been found to be associated closely with many diseases, including cancer. A number of studies have been conducted to investigate the role of ERs in gastric cancer, the possible mechanisms underlying these roles, and the clinical relevance of deregulated ERs in gastric cancer patients. To date, inconsistent associations of different ERs with gastric cancer have been reported. These inconsistencies may be caused by variations in in vitro cell models and clinical samples, including assay conditions and protocols with regard to different forms of ERs. Given the potential of the deregulated ERs as diagnostic/prognostic markers or therapeutic targets for gastric cancer, it will be important to identify/confirm the association of each ER isoform with gastric cancer, to determine the specific roles and interactions that these individual ER isoforms play under specific conditions in the development and/or progression of gastric cancer, and to elucidate precisely these mechanisms. In this review, we summarize the achievements from early ER studies in gastric cancer to the most up-to-date discoveries, with an effort to provide a comprehensive understanding of the role of ERs roles in gastric cancer and its possible mechanisms. Furthermore, we propose directions for future investigations.

MicroRNAs in colorectal cancer as markers and targets:Recent advances

MicroRNAs are evolutionarily conserved small noncoding RNA molecules encoded by eukaryotic genomic DNA,and function in post-transcriptional regulation of gene expression via base-pairing with complementary sequences in target mRNAs,resulting in translational repression or degradation of target mRNAs.They represent one of the major types of epigenetic modification and play important roles in all aspects of cellular activities.Altered expression of microRNAs has been found in various human diseases including cancer.Many efforts have been made to discover the characteristic microRNA expression profiles,to understand the roles of aberrantly expressed microRNAs and underlying mechanisms in different cancers.With the application of DNA microarray,real-time quantitative polymerase chain reaction and other molecular biology techniques,increasing evidence has been accumulated which reveal that aberrant microRNAs can be detected not only intracellularly within the cancer cells,but also extracellularly in plasma of patients,postulating the potential of aberrant microRNAs as promising diagnostic/prognostic markers and attracting therapeutic targets.This review is intended to provide the most recent advances in microRNA studies in one of the most common cancers,colorectal cancer,especially the identification of those specifically altered microRNAs in colorectal cancer,validation for their relevance to clinical pathological parameters of patients,functional analyses and potential applications of these microRNAs.

Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract

AIM： To provide the expression profile of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 （HAI-1） in normal and malignant tissues of gastrointestinal tract at mRNA level for further study on their correlations with tumor progression and metastasis. METHODS： Total RNAs were prepared from 37 samples of colorectal cancer tissues, 40 samples of gastric cancer tissues, and their adjacent normal tissues. The expression of SNC19/matriptase and HAI-1 in these samples was detected by real-time fluorescent quantitative PCR using glyceraldehyde-3-phosphate dehydrogenase as internal standard, and the clinical significance for the correlation with clinicopathological parameters was evaluated. RESULTS： In gastric cancer tissues the expression of HAI-1 and SNC19/matriptase was significantly lower than that in the corresponding adjacent normal tissues （Z = -3.280, P= 0.006; Z= -4.651, P= 0.000）. HAI-1：SNC19/matriptase ratio showed no difference between normal and malignant tissues （P〉0.05）. Analysis of clinicopathological parameters showed decreased expression of HAI-1 and HAI-1：SNC19/ matriptase ratio associated with stage Ⅲ/Ⅳ gastric tumors as compared to stage Ⅰ/Ⅱ ones （Z= -2.140, P= 0.031; Z = -2.155, P = 0.031）, and with lymph node-positive gastric cancer tissues as compared to lymph node-negative ones （Z = -2.081, P = 0.036; Z= -2.686, P = 0.006）. The expression of SNC19/matriptase had no relationship with stages and lymph node metastasis （P〉0.05）. The expression of HAI-1 and HAI-1：SNC19/matriptase ratio increased in well-differentiated gastric cancer tissues, but there was no statistical significance （P〉0.05）. The difference of SNC19/matriptase expression was not significant in gastric cancer tissues of different histological differentiation status （P〉0.05）. In colorectal cancer tissues, the expression of HAI-1 and SNC19/matriptase was also markedly lower than that in their adjacent normal tissues （Z= -3.100, P = 0.002; Z= -2.731, P = 0.006）, whereas HAI-1：SNC19/matriptase ratio showed no difference. Decreased expression of HAI-1 was associated with increased invasive depth and lymph node metastasis, but there was no statistical significance （P〉0.05）. The difference of SNC19/matriptase expression and HAI-1： SNC19/matriptase ratio was not significant in different stages and different lymph node metastasis status （P〉0.05）. The expression of SNC19/matriptase, HAI-1 or HAI-1： SNC19/matriptase ratio showed no difference in colorectal cancer tissues of different histological differentiation status （P〉0.05）. CONCLUSION： The expressions of SNC19/matriptase and its inhibitor HAI-1 are decreased in gastrointestinal cancer tissues compared to their normal counterparts, and the decreased expression of HAI-1 may correlate with invasion and lymph node metastasis. The possible mechanisms involved need to be further investigated.

Ruxolitinib attenuates secondary injury after traumatic spinal cord injury

Excessive inflammation post-traumatic spinal cord injury(SCI)induces microglial activation,which leads to prolonged neurological dysfunction.However,the mechanism underlying microglial activation-induced neuroinflammation remains poorly understood.Ruxolitinib(RUX),a selective inhibitor of JAK1/2,was recently reported to inhibit inflammatory storms caused by SARS-CoV-2 in the lung.However,its role in disrupting inflammation post-SCI has not been confirmed.In this study,microglia were treated with RUX for 24 hours and then activated with interferon-γfor 6 hours.The results showed that interferon-γ-induced phosphorylation of JAK and STAT in microglia was inhibited,and the mRNA expression levels of pro-inflammatory cytokines tumor necrosis factor-α,interleukin-1β,interleukin-6,and cell proliferation marker Ki67 were reduced.In further in vivo experiments,a mouse model of spinal cord injury was treated intragastrically with RUX for 3 successive days,and the findings suggest that RUX can inhibit microglial proliferation by inhibiting the interferon-γ/JAK/STAT pathway.Moreover,microglia treated with RUX centripetally migrated toward injured foci,remaining limited and compacted within the glial scar,which resulted in axon preservation and less demyelination.Moreover,the protein expression levels of tumor necrosis factor-α,interleukin-1β,and interleukin-6 were reduced.The neuromotor function of SCI mice also recovered.These findings suggest that RUX can inhibit neuroinflammation through inhibiting the interferon-γ/JAK/STAT pathway,thereby reducing secondary injury after SCI and producing neuroprotective effects.

Comparison of the modified Wiltse’s approach with spinal minimally invasive system and traditional approach for the therapy of thoracolumbar fracture

Thoracolumbar fractures are usually treated by open posterior pedicle screw fixation.However,this procedure involves massive paraspinal muscle stripping,inflicting surgical trauma,and prolonged X-ray exposure.In this study,we observed 127 patients with single-segment injury thoracolumbar fractures.Thirty-six patients were treated by the modified Wiltse’s paraspinal approach with minimally invasive channel system,while 91 patients were treated via traditional posterior approach.Operation time,intraoperative blood loss,intraoperative fluoroscopy frequency,screw placement accuracy,visual analogue scale score,and Cobb’s angle of two groups were compared.The X-ray exposure times were notably reduced(4.2±1.6) in the new approach group(P<0.05).The pedicle screw placement accuracy and Cobb’s angle after surgery were similar in the two groups.We conclude that modified Wiltse’s paraspinal approach w ith spinal minimally invasive channel system surgery can significantly reduce the X-ray exposure times and is an alternative therapy for the thoracolumbar fracture.

A comparison of robot-assisted and fluoroscopy-assisted kyphoplasty in the treatment of multi-segmental osteoporotic vertebral compression fractures

Osteoporotic vertebral compression fracture(OVCF)has become a major public health issue that becomes more pressing with increasing global aging.Percutaneous kyphoplasty(PKP)is an effective treatment for OVCF.Robot-assisted PKP has been utilized in recent years to improve accuracy and reduce complications.However,the effectiveness of robot-assisted PKP in the treatment of multi-segmental OVCF has yet to be proved.This study was designed to compare the efficacy of robot-assisted and conventional fluoroscopy-assisted multi-segmental PKP.A total of 30 cases with multi-segmental OVCF between April 2019 and April 2021 were included in this study.Fifteen cases were assigned to the robot-assisted PKP group(robot group)and 15 cases to the conventional fluoroscopy-assisted PKP group(conventional fluoroscopy group).The number of fluoroscopic exposures,fluoroscopic dose,operation time,cement leakage rate,visual analog scale(VAS)score,vertebral kyphosis angle(VKA),and height of fractured vertebral body(HFV)were compared between the 2 groups.The number of fluoroscopic exposures,fluoroscopic doses,and cement leakage rates in the robot group were lower than in the conventional fluoroscopy group(P<0.05)while the operative time in the robot group was longer than in the conventional fluoroscopy group(P<0.05).VAS score and VKA were decreased and HFV was increased after surgery in both groups(P<0.05).Therefore,robot-assisted PKP for the treatment of multi-segmental OVCF can reduce the number of fluoroscopic exposures,fluoroscopic doses,and cement leakage compared to conventional treatment.As such,robot-assisted PKP has good application prospects and is potentially more effective in the treatment of multi-segmental OVCF.

髋关节置换术后并发脑梗死的危险因素研究

目的通过分析髋关节置换术后并发脑梗死患者的临床资料,探讨髋关节置换术后并发脑梗死的危险因素。方法 2014年9月至2017年6月行髋关节置换术418例患者,其中9例(2.2%)术后并发脑梗死,对可能导致髋关节置换术后并发脑梗死的危险因素进行单因素和多因素分析。结果单因素分析结果显示年龄、BMI、疾病类型、高血压病史、糖尿病史、心律失常史、脑卒中史、围手术期抗凝、美国麻醉医师协会(ASA)评级、术中低血压为髋关节置换术后并发脑梗死的危险因素;多因素分析结果显示年龄、心律失常史、ASA评级≥Ⅲ级、术中低血压为髋关节置换术后并发脑梗死的危险因素。结论年龄、心律失常史、ASA评级≥Ⅲ级、术中低血压为髋关节置换术后并发脑梗死的独立危险因素,围术期应采取针对性措施加以预防。

MLST analysis of genetic diversity of Bacillus coagulans strains to evaluate effects on constipation model

Bacillus coagulans can help ameliorate or prevent gastrointestinal diseases, but the genetic relationships among B. coagulans isolates are not well studied. Multilocus sequence typing analysis was conducted on 57 isolates of B. coagulans from 22 provinces or autonomous regions in China. B. coagulans isolates were highly diverse and a total of 33(sequence typings) STs were found. These isolates had a weak clonal population structure and strong indications of intraspecies recombination. The evolution direction of B. coagulans was not correlated with geography or isolation source. Fifteen strains were selected for further analysis based on proximity relationships from the phylogenetic tree. Five isolates(B. coagulans-1, B. coagulans-10, B. coagulans-39, B. coagulans-70 and B. coagulans-71) with good spore-forming ability relative to the rest of the isolates were evaluated for constipation relief. B. coagulans-39 significantly relieved constipation symptoms in mice by regulating intestinal flora, increasing the production of short-chain fatty acids and restoring the level of gastrointestinal regulatory peptides. Comparative genomic analysis showed the beneficial effects of B. coagulans-39 might be associated with specific functional genes that are involved in the utilization of various carbohydrates as primary substrates and short-chain fatty acid production.

Tangential stress analysis of myocardial wall by finite element method

A novel method is presented to build the triangular surface model and calculate the tangential stress and strain of myocardial wall ,which can be further used to reflect the left ventricle twisting—a sensitive index to assess the systolic and diastolic function of heart. Firstly, a point distribution model is used to obtain the feature points of the ventricular surface in medical images. Secondly, the surface model is constructed by triangular mesh, and then the subdivision strategy is introduced to refine the model. Thirdly, plane projection and finite element method(FEM) are applied to calculate the tangential stress and strain.Finally, the distribution of tangential modulus of elasticity is discussed. The stimulation results show that the proposed method can be used to compute the tangential stress and strain of myocardial wall effectively and the computing result is consistent with the results mentioned in the literatures.

通过高通量研究识别用于本征陡坡晶体管的原子级薄孤立能带沟道材料

Developing low-power FETs holds significant importance in advancing logic circuits,especially as the feature size of MOSFETs approaches sub-10 nanometers.However,this has been restricted by the thermionic limitation of SS,which is limited to 60 mV per decade at room temperature.Herein,we proposed a strategy that utilizes 2D semiconductors with an isolated-band feature as channels to realize subthermionic SS in MOSFETs.Through high-throughput calculations,we established a guiding principle that combines the atomic structure and orbital interaction to identify their sub-thermionic transport potential.This guides us to screen 192 candidates from the 2D material database comprising 1608 systems.Additionally,the physical relationship between the sub-thermionic transport performances and electronic structures is further revealed,which enables us to predict 15 systems with promising device performances for low-power applications with supply voltage below 0.5 V.This work opens a new way for the low-power electronics based on 2D materials and would inspire extensive interests in the experimental exploration of intrinsic steep-slope MOSFETs.

BCMA-CD19 bispecific CAR-T therapy in refractory chronic inflammatory demyelinating polyneuropathy

Chronic inflammatory demyelinating polyneuropathy(CIDP)is a rare immune-mediated disease characterized by refractory and relapsed peripheral nerve and nerve root damage,leading to severe sequelae for patients.Although glucocorticoids,intravenous immunoglobulin(IVIg),and immunosuppressive agents are recommended for treating CIDP and preventing relapses,some patients’conditions cannot be effectively controlled.Due to the uncertain efficacy and toxicity issues of broad-spectrum immune-modulatory or suppressive drugs,developing a safe and effective treatment strategy is warranted.

厦门新体育场车辐式索桁结构预应力施工全过程分析

近年来随着多种新型大跨度空间结构形式的不断涌现,并在大型公共建筑中得到广泛应用,现场预应力施工面临相当的挑战。通过对当前预应力张拉施工过程模拟方法的简单梳理,并结合具体工程算例,对厦门新体育场车辐式索桁结构预应力施工进行全过程分析。厦门新体育中心体育场又名白鹭体育场,建筑面积18.06万m^(2),预计作为2023年亚洲杯比赛足球场,由南北向巨拱、内环桁架、周边桁架、正交正放连系网架以及位于罩棚中心的马鞍形车辐式索桁结构组成。其中,车辐式索桁结构由40组索桁架和环索组成,钢屋盖东西长度为326 m,南北长度为350 m,平面投影为143 m×95 m的椭圆形,空间呈马鞍形,罩棚东西侧最大标高分别为77 m和85 m,南北侧最大标高分别为24 m和32.5 m,是国内高差最大的体育场结构。索桁结构的径向索锚固于巨拱结构和巨拱之间的连系网架上。针对该创新结构体系构造复杂、索系施工体量大、马鞍面高差大、整体提升与同步张拉协同性要求高等重、难点,创新性地提出了车辐式索桁结构的五阶段提升过程施工方案,其核心步骤为:低空组装—牵引提升—分批锚固—钢撑吊装—高空张拉。而后利用LS-DYNA动力分析软件对预应力拉索施工进行了全过程数值模拟,通过工况划分,分别对提升阶段、钢斜撑安装阶段、上径向索锚固阶段和张拉阶段进行施工模拟验算,并与设计施工阶段的结果进行对比,以验证五阶段提升方案的可操作性。研究表明:位移变形与索力云图模拟值与设计值基本吻合;五阶段提升方案与传统提升方案相比在安全、质量、临设和进度控制等方面具有一定优势;通过有限元软件进行找形分析、找力分析和荷载分析的计算简洁性与便利性仍有大幅度提升空间;采用开发集成交互分析软件进行施工过程动态模拟可以为索结构预应力全过程施工提供稳定技术保障和广阔应用前景。

基于碳纳米管包覆超细全硫化丁腈粉末橡胶制备抗静电聚氯乙烯复合材料的研究

以碳纳米管(CNTs)包覆超细全硫化丁腈粉末橡胶(NB-UFPR)复合微球为导电剂,采用熔融共混的方法制备了聚氯乙烯/碳纳米管-超细全硫化丁腈粉末橡胶(PVC/CNTs-(NB-UFPR))复合材料,并对复合材料的表面电阻率、CNTs分散性和力学性能进行研究。结果表明:相较于PVC/CNTs复合材料,当NB-UFPR为8份,CNTs导电剂逾渗阈值降至3份,PVC复合材料的表面电阻率降至4.0×10^(7)Ω。此外,PVC复合材料的冲击强度由2.27 kJ/m;增至7.17 kJ/m^(2),耐热性也略有提高。因此,NB-UFPR对CNTs的辅助分散作用,使PVC/CNTs-(NB-UFPR)复合材料具有优异的抗静电性和力学性能,进一步扩大PVC材料的应用范围。