The utilization of eco-friendly,lightweight,high-efficiency and high-absorbing electromagnetic interference(EMI)shielding composites is imperative in light of the worldwide promotion of sustainable manufacturing.In th...The utilization of eco-friendly,lightweight,high-efficiency and high-absorbing electromagnetic interference(EMI)shielding composites is imperative in light of the worldwide promotion of sustainable manufacturing.In this work,magnetic poly(butyleneadipate-coterephthalate)(PBAT)microspheres were firstly synthesized via phase separation method,then PBAT composite foams with layered structure was constructed through the supercritical carbon dioxide foaming and scraping techniques.The merits of integrating ferroferric oxideloaded multi-walled carbon nanotubes(Fe3O4@MWCNTs)nanoparticles,a microcellular framework,and a highly conductive silver layer have been judiciously orchestrated within this distinctive layered configuration.Microwaves are consumed throughout the process of“absorption-reflection-reabsorption”as much as possible,which greatly declines the secondary radiation pollution.The biodegradable PBAT composite foams achieved an EMI shielding effectiveness of up to 68 dB and an absorptivity of 77%,and authenticated favorable stabilization after the tape adhesion experiment.展开更多
To address the shortage of public datasets for customs X-ray images of contraband and the difficulties in deploying trained models in engineering applications,a method has been proposed that employs the Extract-Transf...To address the shortage of public datasets for customs X-ray images of contraband and the difficulties in deploying trained models in engineering applications,a method has been proposed that employs the Extract-Transform-Load(ETL)approach to create an X-ray dataset of contraband items.Initially,X-ray scatter image data is collected and cleaned.Using Kafka message queues and the Elasticsearch(ES)distributed search engine,the data is transmitted in real-time to cloud servers.Subsequently,contraband data is annotated using a combination of neural networks and manual methods to improve annotation efficiency and implemented mean hash algorithm for quick image retrieval.The method of integrating targets with backgrounds has enhanced the X-ray contraband image data,increasing the number of positive samples.Finally,an Airport Customs X-ray dataset(ACXray)compatible with customs business scenarios has been constructed,featuring an increased number of positive contraband samples.Experimental tests using three datasets to train the Mask Region-based Convolutional Neural Network(Mask R-CNN)algorithm and tested on 400 real customs images revealed that the recognition accuracy of algorithms trained with Security Inspection X-ray(SIXray)and Occluded Prohibited Items X-ray(OPIXray)decreased by 16.3%and 15.1%,respectively,while the ACXray dataset trained algorithm’s accuracy was almost unaffected.This indicates that the ACXray dataset-trained algorithm possesses strong generalization capabilities and is more suitable for customs detection scenarios.展开更多
Jinjiang oyster Crassostrea ariakensis,a species with economic and ecological value,is distributed along the estuaries and coasts of East Asia.With the decline in natural resources,the conservation and aquaculture of ...Jinjiang oyster Crassostrea ariakensis,a species with economic and ecological value,is distributed along the estuaries and coasts of East Asia.With the decline in natural resources,the conservation and aquaculture of this species is urgent.However,studies characterizing their shell shape remain scarce.We investigated the morphological differences in the shells of wild Jinjiang oysters from six populations(Qinzhou,Shanghai,Nantong,Qingdao,and Binzhou hard or muddy bottom)along the coast of China.The color of the shell and adductor muscle scar showed associations with temperature gradient along its geographical distribution.Oyster shape was defined by shell height to shell length ratio,and the ratio varies among geographic locations of the populations.They were found nearly round(Qinzhou and Nantong populations),oval(Qingdao and Binzhou populations),or water-droplet-shaped(Shanghai population).Binzhou populations living on muddy substrates are more elongated than those on hard substrate.In addition,we developed a method to measure the cavity volume in oysters.Correlation and path analysis showed that shell height significantly influenced cavity volume.The synergistic effect of the two factors(the height,length,and width of the shell in pairs)on the cavity volume resulted in differences between northern and southern groups:samples from the southern group(Qinzhou and Shanghai)showed correlation between shell height and shell width,while those from the northern group(Nantong,Qingdao,and Binzhou)showed correlation between shell height and shell length.All populations showed significant correlation between shell height and cavity height,and shell length and cavity length,while the correlation between shell width and cavity width was minimal,which may have been resulted from uneven shell thickness.The linear equation for shell height and cavity volume under different ratios of shell height to length was obtained.In this study,we determined that shell height has the most influence on cavity volume,and specific cavity volume fitting linear equations are given for different shell types,which may provide a reference for future oyster breeding for shell shaping.展开更多
Functional magnetic resonance imaging studies have shown that the insular cortex has a signif- icant role in pain identification and information integration, while the default mode network is associated with cognitive...Functional magnetic resonance imaging studies have shown that the insular cortex has a signif- icant role in pain identification and information integration, while the default mode network is associated with cognitive and memory-related aspects of pain perception. However, changes in the functional connectivity between the defauk mode network and insula during pain remain unclear. This study used 3.0 T functional magnetic resonance imaging scans in 12 healthy sub- jects aged 24.8 ± 3.3 years to compare the differences in the functional activity and connectivity of the insula and default mode network between the baseline and pain condition induced by intramuscular injection of hypertonic saline. Compared with the baseline, the insula was more functionally connected with the medial prefrontal and lateral temporal cortices, whereas there was lower connectivity with the posterior cingulate cortex, precuneus and inferior parietal lobule in the pain condition. In addition, compared with baseline, the anterior cingulate cortex exhibited greater connectivity with the posterior insula, but lower connectivity with the anterior insula, during the pain condition. These data indicate that experimental low back pain led to dysfunction in the connectivity between the insula and default mode network resulting from an impairment of the regions of the brain related to cognition and emotion, suggesting the impor- tance of the interaction between these regions in pain processing.展开更多
Defect passivation is one of the most important strategies to boost both the efficiency and stability of perovskite solar cells(PSCs).Here,nontoxic and sustainable forest-based biomaterial,betulin,is first introduced ...Defect passivation is one of the most important strategies to boost both the efficiency and stability of perovskite solar cells(PSCs).Here,nontoxic and sustainable forest-based biomaterial,betulin,is first introduced into perovskites.The experiments and calculations reveal that betulin can effectively passivate the uncoordinated lead ions in perovskites via sharing the lone pair electrons of hydroxyl group,promoting charge transport.As a result,the power conversion efficiencies of the p-i-n planar PSCs remarkably increase from 19.14%to 21.15%,with the improvement of other parameters.The hydrogen bonds of betulin lock methylamine and halogen ions along the grain boundaries and on the film surface and thus suppress ion migration,further stabilizing perovskite crystal structures.These positive effects enable the PSCs to maintain 90%of the initial efficiency after 30 days in ambient air with 60%±5%relative humidity,75%after 300 h aging at 85℃,and 55%after 250 h light soaking,respectively.This work opens a new pathway for using nontoxic and low-cost biomaterials from forest to make highly efficient and stable PSCs.展开更多
Surface passivation via post-treatment is an important strategy for improving power conversion efficiency and operational stability of perovskite solar cells.However,so far the interaction mechanisms between passivati...Surface passivation via post-treatment is an important strategy for improving power conversion efficiency and operational stability of perovskite solar cells.However,so far the interaction mechanisms between passivating additive and perovskite are not well understood.Here,we report the atomic-scale interaction of surface passivating additive 2,2-difluoroethylammonium bromine(2FEABr)on the MAPbI_(3).It is found that the bulky 2FEA+cations tend to distribute at film surface,while the Br−anions diffuse from surface into bulk.A combination of 19F,207Pb,and 2H solid-state NMR further reveal the Br−anions’partial substitution for the I−sites,the restricted motion of partial MA+cations,and the firmed perovskite lattices,which would improve charge transport and stability of the perovskite films.Optical spectroscopy and ultraviolet photoelectron spectroscopy demonstrate that the 2FEABr induced surface passivation and energetic modification suppress the nonradiative recombination loss.These findings enable the efficiency of the p-i-n structured PSC significantly increasing from 19.44 to 21.06%,accompanied by excellent stability.Our work further establishes more knowledge link between passivating additive and PSC performance.展开更多
Organic solar cells(OSCs)have attracted huge attention because of their unique merits[1−3].In last few years,thanks to the design of new materials and device engineering,the power conversion efficiencies(PCEs)of OSCs ...Organic solar cells(OSCs)have attracted huge attention because of their unique merits[1−3].In last few years,thanks to the design of new materials and device engineering,the power conversion efficiencies(PCEs)of OSCs have surpassed 18%[4−8].The PM6:Y6 cells are efficient binary cells,offering high PCEs over 16%[9−11].The high performance originates from the efficient free charge generation and the ground state dipole field at the donor-acceptor interface that promotes the exciton dissociation[12].展开更多
The impacts of global climate change on ski tourism, which depends heavily on climate conditions, have increasingly gained concern overseas. This paper systematically summarized the relevant research ideas, the techni...The impacts of global climate change on ski tourism, which depends heavily on climate conditions, have increasingly gained concern overseas. This paper systematically summarized the relevant research ideas, the technical methods used, and the obtained achievements through an extensive synthesis of the previous studies. Moreover, the major shortcomings and the limitations in the recent studies are pointed in order to present a useful reference for our Chinese investigators. It indicates that the future climate warming would cause the loss of skiable areas, the shortening of skiing seasons and the sharp drop of ski visitors in many low altitude and low latitude ski resorts. The paper finally stressed that future research should pay particular attention to strengthening interdisciplinary cooperation and consider more factors about the impacts of climate-induced environmental changes on tourist flows. In the future ski resort planning and management, the possible impacts of global climate change should be taken into account.展开更多
The mucosal barrier is crucial for intestinal homeostasis,and goblet cells are essential for maintaining the mucosal barrier integrity.The proviral integration site for Moloney murine leukemia virus-1(PIM1)kinase regu...The mucosal barrier is crucial for intestinal homeostasis,and goblet cells are essential for maintaining the mucosal barrier integrity.The proviral integration site for Moloney murine leukemia virus-1(PIM1)kinase regulates multiple cellular functions,but its role in intestinal homeostasis during colitis is unknown.Here,we demonstrate that PIM1 is prominently elevated in the colonic epithelia of both ulcerative colitis patients and murine models,in the presence of intestinal microbiota.Epithelial PIM1 leads to decreased goblet cells,thus impairing resistance to colitis and colitis-associated colorectal cancer(CAC)in mice.Mechanistically,PIM1 modulates goblet cell differentiation through the Wnt and Notch signaling pathways.Interestingly,PIM1 interacts with histone deacetylase 2(HDAC2)and downregulates its level via phosphorylation,thereby altering the epigenetic profiles of Wnt signaling pathway genes.Collectively,these findings investigate the unknown function of the PIM1-HDAC2 axis in goblet cell differentiation and ulcerative colitis/CAC pathogenesis,which points to the potential for PIM1-targeted therapies of ulcerative colitis and CAC.展开更多
Reflective and insulative composite coatings are a new energy-saving material with high solar reflectance and extremely low thermal conductivity for buildings.The optimization and impact of high solar reflectance and ...Reflective and insulative composite coatings are a new energy-saving material with high solar reflectance and extremely low thermal conductivity for buildings.The optimization and impact of high solar reflectance and low thermal conductivity on the insulating capacity of walls remain uncertain.This work investigates the dynamic thermal performance and energy efficiency of a reflective and insulative composite coating in regions with hot summer and warm winter.A simplified thermal resistance-heat capacitance model of an exterior building wall is established to predict thermal performance.The dynamic temperature and heat flow of the wall are predicted to reduce heat loss through the interior surface of the wall and compared to the conventional coating.The specific impact of the thermal conductivity and solar reflectance of the coating on the heat loss is further investigated to minimize heat loss of the wall.This research shows that the composite coating shows better performance on adjusting outdoor climate change than the other coating.Compared with cement,it reduces the maximum temperature of the exterior surface of the wall by 7.45°C,and the heat loss through the interior surface of the wall by 38%.The heat loss is reduced with the increase of solar reflectance and the reduction of thermal conductivity.The results can provide a useful reference and guidance for the application of reflective and insulative composite coating on building exterior wall to promote their energy-saving use on building envelopes.展开更多
Dear Editor,To decipher brain functions,brain cells are generally prelabeled and then imaged using a high-resolution confocal system,and manual or automatic counting methods are widely used in the quantitative and sem...Dear Editor,To decipher brain functions,brain cells are generally prelabeled and then imaged using a high-resolution confocal system,and manual or automatic counting methods are widely used in the quantitative and semiquantitative analysis of these confocal images.Therefore,cell counting becomes a bottleneck in efficient analysis because manual counting is laborious and time-consuming.Therefore,an accurate and user-friendly automated cell counting tool is needed for biological researchers.展开更多
Body-fitted mesh generation has long been the bottleneck of simulating fluid flows involving complex geometries. Immersed boundary methods are non-boundary-conforming methods that have gained great popularity in the l...Body-fitted mesh generation has long been the bottleneck of simulating fluid flows involving complex geometries. Immersed boundary methods are non-boundary-conforming methods that have gained great popularity in the last two decades for their simplicity and flexibility, as well as their non-compromised accuracy. This paper presents a summary of some numerical algori- thms along the line of sharp interface direct forcing approaches and their applications in some practical problems. The algorithms include basic Navier-Stokes solvers, immersed boundary setup procedures, treatments of stationary and moving immersed bounda- ries, and fluid-structure coupling schemes. Applications of these algorithms in particulate flows, flow-induced vibrations, biofluid dynamics, and free-surface hydrodynamics are demonstrated. Some concluding remarks are made, including several future research directions that can further expand the application regime of immersed boundary methods.展开更多
This paper describes a novel sharp interface approach for modeling the cavitation phenomena in incompressible viscous flows. A one-field formulation is adopted for the vapor-liquid two-phase flow and the interface is ...This paper describes a novel sharp interface approach for modeling the cavitation phenomena in incompressible viscous flows. A one-field formulation is adopted for the vapor-liquid two-phase flow and the interface is tracked using a volume of fluid(VOF) method. Phase change at the interface is modeled using a simplification of the Rayleigh-Plesset equation. Interface jump conditions in velocity and pressure field are treated using a level set based ghost fluid method. The level set function is constructed from the volume fraction function. A marching cubes method is used to compute the interface area at the interface grid cells. A parallel fast marching method is employed to propagate interface information into the field. A description of the equations and numerical methods is presented. Results for a cavitating hydrofoil are compared with experimental data.展开更多
Pathological anxiety is among the most difficult neuropsychiatric diseases to treat pharmacologically,and it represents a major societal problem.Studies have implicated structural changes within the prefrontal cortex(...Pathological anxiety is among the most difficult neuropsychiatric diseases to treat pharmacologically,and it represents a major societal problem.Studies have implicated structural changes within the prefrontal cortex(PFC)and functional changes in the communication of the PFC with distal brain structures in anxiety disorders.Treatments that affect the activity of the PFC,including cognitive therapies and transcranial magnetic stimulation,reverse anxiety-and fear-associated circuit abnormalities through mechanisms that remain largely unclear.While the subjective experience of a rodent cannot be precisely determined,rodent models hold great promise in dissecting well-conserved circuits.Newly developed genetic and viral tools and optogenetic and chemogenetic techniques have revealed the intricacies of neural circuits underlying anxiety and fear by allowing direct examination of hypotheses drawn from existing psychological concepts.This review focuses on studies that have used these circuit-based approaches to gain a more detailed,more comprehensive,and more integrated view on how the PFC governs anxiety and fear and orchestrates adaptive defensive behaviors to hopefully provide a roadmap for the future development of therapies for pathological anxiety.展开更多
Decoupled radiant cooling units(DRCUs)are capable of increasing the cooling capacity without increasing condensation risks even using a much lower cooling temperature than conventional radiant cooling units(CRCUs).How...Decoupled radiant cooling units(DRCUs)are capable of increasing the cooling capacity without increasing condensation risks even using a much lower cooling temperature than conventional radiant cooling units(CRCUs).However,it is unclear whether DRCUs using low radiant cooling temperature will increase the cooling load of the conditioned indoor spaces.In this study,the cooling load characteristics of a thermal chamber conditioned by a DRCU was investigated through developing a steady-state analysis model suitable for both DRCUs and CRCUs.The total/radiative heat flux,as well as the heat exchange with a thermal manikin and walls were analysed under different surface temperatures of DRCUs.The effect of the emissivity of the thermal chamber’external wall on the cooling load was also investigated.Results indicated that the cooling load under the DRCU was slightly smaller than that under the CRCU when the same operative environment was created.Decreasing the infrared emissivity of the exterior wall’s inner surface could lead to a significant decrease in the cooling load for both the DRCU and CRCU.By decreasing the wall emissivity from 0.9 to 0.1,the total cooling load of the DRCU can be decreased by 8.4%and the heat gain of the exterior wall decreased by 21.6%.This study serves as a reference for developing the analysis model and understanding the load characteristics when DRCUs are used to create the thermal environment for indoor spaces.展开更多
基金This work was supported by the National Natural Science Foundation of China(No.U21A2093)the Anhui Provincial Natural Science Foundation(No.2308085QE146)the National Natural Science Foundation of Jiangsu Province(No.BK20210894).
文摘The utilization of eco-friendly,lightweight,high-efficiency and high-absorbing electromagnetic interference(EMI)shielding composites is imperative in light of the worldwide promotion of sustainable manufacturing.In this work,magnetic poly(butyleneadipate-coterephthalate)(PBAT)microspheres were firstly synthesized via phase separation method,then PBAT composite foams with layered structure was constructed through the supercritical carbon dioxide foaming and scraping techniques.The merits of integrating ferroferric oxideloaded multi-walled carbon nanotubes(Fe3O4@MWCNTs)nanoparticles,a microcellular framework,and a highly conductive silver layer have been judiciously orchestrated within this distinctive layered configuration.Microwaves are consumed throughout the process of“absorption-reflection-reabsorption”as much as possible,which greatly declines the secondary radiation pollution.The biodegradable PBAT composite foams achieved an EMI shielding effectiveness of up to 68 dB and an absorptivity of 77%,and authenticated favorable stabilization after the tape adhesion experiment.
基金supported by the National Natural Science Foundation of China(Grant No.51605069).
文摘To address the shortage of public datasets for customs X-ray images of contraband and the difficulties in deploying trained models in engineering applications,a method has been proposed that employs the Extract-Transform-Load(ETL)approach to create an X-ray dataset of contraband items.Initially,X-ray scatter image data is collected and cleaned.Using Kafka message queues and the Elasticsearch(ES)distributed search engine,the data is transmitted in real-time to cloud servers.Subsequently,contraband data is annotated using a combination of neural networks and manual methods to improve annotation efficiency and implemented mean hash algorithm for quick image retrieval.The method of integrating targets with backgrounds has enhanced the X-ray contraband image data,increasing the number of positive samples.Finally,an Airport Customs X-ray dataset(ACXray)compatible with customs business scenarios has been constructed,featuring an increased number of positive contraband samples.Experimental tests using three datasets to train the Mask Region-based Convolutional Neural Network(Mask R-CNN)algorithm and tested on 400 real customs images revealed that the recognition accuracy of algorithms trained with Security Inspection X-ray(SIXray)and Occluded Prohibited Items X-ray(OPIXray)decreased by 16.3%and 15.1%,respectively,while the ACXray dataset trained algorithm’s accuracy was almost unaffected.This indicates that the ACXray dataset-trained algorithm possesses strong generalization capabilities and is more suitable for customs detection scenarios.
基金Supported by the Key R&D Program Project of Shandong Province (No.2021LZGC029)the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDA23050402)+3 种基金the Young Elite Scientists Sponsorship Program by China Association of Science and Technology (No.2021QNRC001)the Technology and the Modern Agroindustry Technology Research System (No.CARS-49)the Innovation Capacity Improvement Project of Small and Medium-Sized Technology-Based Enterprise of Shandong Province (No.2022TSGC1125)the Key Technology Research and Industrialization Demonstration Projects of Qingdao,China (No.22-3-3-hygg-2-hy)。
文摘Jinjiang oyster Crassostrea ariakensis,a species with economic and ecological value,is distributed along the estuaries and coasts of East Asia.With the decline in natural resources,the conservation and aquaculture of this species is urgent.However,studies characterizing their shell shape remain scarce.We investigated the morphological differences in the shells of wild Jinjiang oysters from six populations(Qinzhou,Shanghai,Nantong,Qingdao,and Binzhou hard or muddy bottom)along the coast of China.The color of the shell and adductor muscle scar showed associations with temperature gradient along its geographical distribution.Oyster shape was defined by shell height to shell length ratio,and the ratio varies among geographic locations of the populations.They were found nearly round(Qinzhou and Nantong populations),oval(Qingdao and Binzhou populations),or water-droplet-shaped(Shanghai population).Binzhou populations living on muddy substrates are more elongated than those on hard substrate.In addition,we developed a method to measure the cavity volume in oysters.Correlation and path analysis showed that shell height significantly influenced cavity volume.The synergistic effect of the two factors(the height,length,and width of the shell in pairs)on the cavity volume resulted in differences between northern and southern groups:samples from the southern group(Qinzhou and Shanghai)showed correlation between shell height and shell width,while those from the northern group(Nantong,Qingdao,and Binzhou)showed correlation between shell height and shell length.All populations showed significant correlation between shell height and cavity height,and shell length and cavity length,while the correlation between shell width and cavity width was minimal,which may have been resulted from uneven shell thickness.The linear equation for shell height and cavity volume under different ratios of shell height to length was obtained.In this study,we determined that shell height has the most influence on cavity volume,and specific cavity volume fitting linear equations are given for different shell types,which may provide a reference for future oyster breeding for shell shaping.
基金supported by the Science and Technology Foundation of Guangdong Province of China,No.2012B031800305
文摘Functional magnetic resonance imaging studies have shown that the insular cortex has a signif- icant role in pain identification and information integration, while the default mode network is associated with cognitive and memory-related aspects of pain perception. However, changes in the functional connectivity between the defauk mode network and insula during pain remain unclear. This study used 3.0 T functional magnetic resonance imaging scans in 12 healthy sub- jects aged 24.8 ± 3.3 years to compare the differences in the functional activity and connectivity of the insula and default mode network between the baseline and pain condition induced by intramuscular injection of hypertonic saline. Compared with the baseline, the insula was more functionally connected with the medial prefrontal and lateral temporal cortices, whereas there was lower connectivity with the posterior cingulate cortex, precuneus and inferior parietal lobule in the pain condition. In addition, compared with baseline, the anterior cingulate cortex exhibited greater connectivity with the posterior insula, but lower connectivity with the anterior insula, during the pain condition. These data indicate that experimental low back pain led to dysfunction in the connectivity between the insula and default mode network resulting from an impairment of the regions of the brain related to cognition and emotion, suggesting the impor- tance of the interaction between these regions in pain processing.
基金supported by the National Natural Science Foundation of China(21875067,51811530011,11604099)the Fundamental Research Funds for the Central Universities,Shanghai Rising-Star(19QA1403100)+2 种基金ECNU Multifunctional Platform for Innovation(006)the National Key Research and Development Program of China(2017YFA0206600)the National Natural Science Foundation of China(51773045,21772030,51922032,21961160720)for financial support。
文摘Defect passivation is one of the most important strategies to boost both the efficiency and stability of perovskite solar cells(PSCs).Here,nontoxic and sustainable forest-based biomaterial,betulin,is first introduced into perovskites.The experiments and calculations reveal that betulin can effectively passivate the uncoordinated lead ions in perovskites via sharing the lone pair electrons of hydroxyl group,promoting charge transport.As a result,the power conversion efficiencies of the p-i-n planar PSCs remarkably increase from 19.14%to 21.15%,with the improvement of other parameters.The hydrogen bonds of betulin lock methylamine and halogen ions along the grain boundaries and on the film surface and thus suppress ion migration,further stabilizing perovskite crystal structures.These positive effects enable the PSCs to maintain 90%of the initial efficiency after 30 days in ambient air with 60%±5%relative humidity,75%after 300 h aging at 85℃,and 55%after 250 h light soaking,respectively.This work opens a new pathway for using nontoxic and low-cost biomaterials from forest to make highly efficient and stable PSCs.
基金supported by the National Science Foundation of China grant(21875067)the Fundamental Research Funds for the Central Universities,Shanghai Rising-Star(19QA1403100)+4 种基金East China Normal University(ECNU)Multifunctional Platform for InnovationThe Ministry of Science and Technology of the People’s Republic of China(No.2018YFF01012504)the National Key Research and Development Program of China(2017YFA0206600)the National Natural Science Foundation of China(51773045,21772030,51922032,21961160720)for financial support。
文摘Surface passivation via post-treatment is an important strategy for improving power conversion efficiency and operational stability of perovskite solar cells.However,so far the interaction mechanisms between passivating additive and perovskite are not well understood.Here,we report the atomic-scale interaction of surface passivating additive 2,2-difluoroethylammonium bromine(2FEABr)on the MAPbI_(3).It is found that the bulky 2FEA+cations tend to distribute at film surface,while the Br−anions diffuse from surface into bulk.A combination of 19F,207Pb,and 2H solid-state NMR further reveal the Br−anions’partial substitution for the I−sites,the restricted motion of partial MA+cations,and the firmed perovskite lattices,which would improve charge transport and stability of the perovskite films.Optical spectroscopy and ultraviolet photoelectron spectroscopy demonstrate that the 2FEABr induced surface passivation and energetic modification suppress the nonradiative recombination loss.These findings enable the efficiency of the p-i-n structured PSC significantly increasing from 19.44 to 21.06%,accompanied by excellent stability.Our work further establishes more knowledge link between passivating additive and PSC performance.
基金supported by the National Natural Science Foundation of China(21875067,11604099,51811530011)the Fundamental Research Funds for the Central Central Universities,Shanghai Rising-Star(19QA1403100)+6 种基金East China Normal University Multifunctional Platform for Innovationthe STINT grant(CH2017-7163)the National Natural Science Foundation of China(51803060)the Science and Technology Program of Guangdong Province(2018A030313045)the National Key Research and Development Program of China(2017YFA0206600)the National Natural Science Foundation of China(51773045,21772030,51922032,21961160720)for financial supportthe open project of State Key Laboratory of Luminescent Materials and Devices(2021-skllmd-07).
文摘Organic solar cells(OSCs)have attracted huge attention because of their unique merits[1−3].In last few years,thanks to the design of new materials and device engineering,the power conversion efficiencies(PCEs)of OSCs have surpassed 18%[4−8].The PM6:Y6 cells are efficient binary cells,offering high PCEs over 16%[9−11].The high performance originates from the efficient free charge generation and the ground state dipole field at the donor-acceptor interface that promotes the exciton dissociation[12].
基金the foundation for the Project of Key Subject of Human Geography of Fujian Normal University for the partial financial support of this research
文摘The impacts of global climate change on ski tourism, which depends heavily on climate conditions, have increasingly gained concern overseas. This paper systematically summarized the relevant research ideas, the technical methods used, and the obtained achievements through an extensive synthesis of the previous studies. Moreover, the major shortcomings and the limitations in the recent studies are pointed in order to present a useful reference for our Chinese investigators. It indicates that the future climate warming would cause the loss of skiable areas, the shortening of skiing seasons and the sharp drop of ski visitors in many low altitude and low latitude ski resorts. The paper finally stressed that future research should pay particular attention to strengthening interdisciplinary cooperation and consider more factors about the impacts of climate-induced environmental changes on tourist flows. In the future ski resort planning and management, the possible impacts of global climate change should be taken into account.
基金supported by grants from the National Natural Science Foundation of China(NSFC)Programs(32170186,82200618,82173199)Tianjin Science and Technology Commissioner Project(22JCZDJC00490,22JCQ NJC00540,China).
文摘The mucosal barrier is crucial for intestinal homeostasis,and goblet cells are essential for maintaining the mucosal barrier integrity.The proviral integration site for Moloney murine leukemia virus-1(PIM1)kinase regulates multiple cellular functions,but its role in intestinal homeostasis during colitis is unknown.Here,we demonstrate that PIM1 is prominently elevated in the colonic epithelia of both ulcerative colitis patients and murine models,in the presence of intestinal microbiota.Epithelial PIM1 leads to decreased goblet cells,thus impairing resistance to colitis and colitis-associated colorectal cancer(CAC)in mice.Mechanistically,PIM1 modulates goblet cell differentiation through the Wnt and Notch signaling pathways.Interestingly,PIM1 interacts with histone deacetylase 2(HDAC2)and downregulates its level via phosphorylation,thereby altering the epigenetic profiles of Wnt signaling pathway genes.Collectively,these findings investigate the unknown function of the PIM1-HDAC2 axis in goblet cell differentiation and ulcerative colitis/CAC pathogenesis,which points to the potential for PIM1-targeted therapies of ulcerative colitis and CAC.
基金the National Natural Science Foundation of China(No.52078144)the National Natural Science Foundation of China(No.52108073)the Innovation Research for Postgraduates of Guangzhou University(No.2021GDJC-D15).
文摘Reflective and insulative composite coatings are a new energy-saving material with high solar reflectance and extremely low thermal conductivity for buildings.The optimization and impact of high solar reflectance and low thermal conductivity on the insulating capacity of walls remain uncertain.This work investigates the dynamic thermal performance and energy efficiency of a reflective and insulative composite coating in regions with hot summer and warm winter.A simplified thermal resistance-heat capacitance model of an exterior building wall is established to predict thermal performance.The dynamic temperature and heat flow of the wall are predicted to reduce heat loss through the interior surface of the wall and compared to the conventional coating.The specific impact of the thermal conductivity and solar reflectance of the coating on the heat loss is further investigated to minimize heat loss of the wall.This research shows that the composite coating shows better performance on adjusting outdoor climate change than the other coating.Compared with cement,it reduces the maximum temperature of the exterior surface of the wall by 7.45°C,and the heat loss through the interior surface of the wall by 38%.The heat loss is reduced with the increase of solar reflectance and the reduction of thermal conductivity.The results can provide a useful reference and guidance for the application of reflective and insulative composite coating on building exterior wall to promote their energy-saving use on building envelopes.
基金supported by grants from the National Natural Science Foundation of China(82090032 and 31830033)the Program for Changjiang Scholars and Innovative Research Team in University(IRT_16R37)+1 种基金the Key Area Research and Development Program of Guangdong Province(2018B030334001 and 2018B030340001)the Science and Technology Program of Guangzhou(202007030013).
文摘Dear Editor,To decipher brain functions,brain cells are generally prelabeled and then imaged using a high-resolution confocal system,and manual or automatic counting methods are widely used in the quantitative and semiquantitative analysis of these confocal images.Therefore,cell counting becomes a bottleneck in efficient analysis because manual counting is laborious and time-consuming.Therefore,an accurate and user-friendly automated cell counting tool is needed for biological researchers.
文摘Body-fitted mesh generation has long been the bottleneck of simulating fluid flows involving complex geometries. Immersed boundary methods are non-boundary-conforming methods that have gained great popularity in the last two decades for their simplicity and flexibility, as well as their non-compromised accuracy. This paper presents a summary of some numerical algori- thms along the line of sharp interface direct forcing approaches and their applications in some practical problems. The algorithms include basic Navier-Stokes solvers, immersed boundary setup procedures, treatments of stationary and moving immersed bounda- ries, and fluid-structure coupling schemes. Applications of these algorithms in particulate flows, flow-induced vibrations, biofluid dynamics, and free-surface hydrodynamics are demonstrated. Some concluding remarks are made, including several future research directions that can further expand the application regime of immersed boundary methods.
基金supported by the NSWC Carderock ILIR programby the US Office of Naval Research(Grant No.N000141-01-00-1-7)
文摘This paper describes a novel sharp interface approach for modeling the cavitation phenomena in incompressible viscous flows. A one-field formulation is adopted for the vapor-liquid two-phase flow and the interface is tracked using a volume of fluid(VOF) method. Phase change at the interface is modeled using a simplification of the Rayleigh-Plesset equation. Interface jump conditions in velocity and pressure field are treated using a level set based ghost fluid method. The level set function is constructed from the volume fraction function. A marching cubes method is used to compute the interface area at the interface grid cells. A parallel fast marching method is employed to propagate interface information into the field. A description of the equations and numerical methods is presented. Results for a cavitating hydrofoil are compared with experimental data.
基金supported by grants from the National Key R&D Program of China(No.2021ZD0202704 to Tianming Gao,No.2022ZD0214300 to Yihua Chen)the National Natural Science Foundation of China(Nos.82090032 and 31830033 to Tianming Gao)+3 种基金the Key Area Research and Development Program of Guangdong Province(Nos.2018B030334001 and 2018B030340001 to Tianming Gao)the Guangdong Basic and Applied Basic Research Foundation(No.2020A1515011310 to Yihua Chen)the Guangdong−Hong Kong−Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence Fund(No.2019019 to Yihua Chen)the Science and Technology Program of Guangzhou(No.202007030013 to Tianming Gao).
文摘Pathological anxiety is among the most difficult neuropsychiatric diseases to treat pharmacologically,and it represents a major societal problem.Studies have implicated structural changes within the prefrontal cortex(PFC)and functional changes in the communication of the PFC with distal brain structures in anxiety disorders.Treatments that affect the activity of the PFC,including cognitive therapies and transcranial magnetic stimulation,reverse anxiety-and fear-associated circuit abnormalities through mechanisms that remain largely unclear.While the subjective experience of a rodent cannot be precisely determined,rodent models hold great promise in dissecting well-conserved circuits.Newly developed genetic and viral tools and optogenetic and chemogenetic techniques have revealed the intricacies of neural circuits underlying anxiety and fear by allowing direct examination of hypotheses drawn from existing psychological concepts.This review focuses on studies that have used these circuit-based approaches to gain a more detailed,more comprehensive,and more integrated view on how the PFC governs anxiety and fear and orchestrates adaptive defensive behaviors to hopefully provide a roadmap for the future development of therapies for pathological anxiety.
基金The study was supported by grants from the Research Grants Council of the Hong Kong Special Administrative Region,China(No.11212919)the National Natural Science Foundation of China(No.52078144).
文摘Decoupled radiant cooling units(DRCUs)are capable of increasing the cooling capacity without increasing condensation risks even using a much lower cooling temperature than conventional radiant cooling units(CRCUs).However,it is unclear whether DRCUs using low radiant cooling temperature will increase the cooling load of the conditioned indoor spaces.In this study,the cooling load characteristics of a thermal chamber conditioned by a DRCU was investigated through developing a steady-state analysis model suitable for both DRCUs and CRCUs.The total/radiative heat flux,as well as the heat exchange with a thermal manikin and walls were analysed under different surface temperatures of DRCUs.The effect of the emissivity of the thermal chamber’external wall on the cooling load was also investigated.Results indicated that the cooling load under the DRCU was slightly smaller than that under the CRCU when the same operative environment was created.Decreasing the infrared emissivity of the exterior wall’s inner surface could lead to a significant decrease in the cooling load for both the DRCU and CRCU.By decreasing the wall emissivity from 0.9 to 0.1,the total cooling load of the DRCU can be decreased by 8.4%and the heat gain of the exterior wall decreased by 21.6%.This study serves as a reference for developing the analysis model and understanding the load characteristics when DRCUs are used to create the thermal environment for indoor spaces.
基金the Open Funding Project of the State Key Laboratory of Bioreactor Engineering,the National Natural Science Foundation of China (Grant Nos.21576134, 21606127,21390200)the National Key Research and Development Program of China (Grant No.2016YFA0204300).