农村儿童创造力与内、外化问题行为的关系

本研究选取339名农村公立小学四年级儿童为研究对象,旨在考察儿童创造力与内、外化问题行为之间的关系。结果显示:(1)独创性与适用性显著负相关;(2)独创性与适用性均显著负向预测内化问题行为;(3)独创性显著负向预测外化问题行为,并且存在独创性与适用性的显著交互效应,表现为独创性对外化问题行为的负向预测作用仅在高适用性水平下显著。本研究结果有助于理解在农村背景下儿童创造力与问题行为的关系。

Modeling and analysis of gradient metamaterials for broad fusion bandgaps

A gradient metamaterial with varying-stiffness local resonators is proposed to open the multiple bandgaps and further form a broad fusion bandgap.First,three local resonators with linearly increasing stiffness are periodically attached to the spring-mass chain to construct the gradient metamaterial.The dispersion relation is then derived based on Bloch's theorem to reveal the fusion bandgap theoretically.The dynamic characteristic of the finite spring-mass chain is investigated to validate the fusion of multiple bandgaps.Finally,the effects of the design parameters on multiple bandgaps are discussed.The results show that the metamaterial with a non-uniform stiffness gradient pattern is capable of opening a broad fusion bandgap and effectively attenuating the longitudinal waves within a broad frequency region.

Adaptive state-constrained/model-free iterative sliding mode control for aerial robot trajectory tracking

This paper develops a novel hierarchical control strategy for improving the trajectory tracking capability of aerial robots under parameter uncertainties.The hierarchical control strategy is composed of an adaptive sliding mode controller and a model-free iterative sliding mode controller(MFISMC).A position controller is designed based on adaptive sliding mode control(SMC)to safely drive the aerial robot and ensure fast state convergence under external disturbances.Additionally,the MFISMC acts as an attitude controller to estimate the unmodeled dynamics without detailed knowledge of aerial robots.Then,the adaption laws are derived with the Lyapunov theory to guarantee the asymptotic tracking of the system state.Finally,to demonstrate the performance and robustness of the proposed control strategy,numerical simulations are carried out,which are also compared with other conventional strategies,such as proportional-integralderivative(PID),backstepping(BS),and SMC.The simulation results indicate that the proposed hierarchical control strategy can fulfill zero steady-state error and achieve faster convergence compared with conventional strategies.

Multi-layer quasi-zero-stiffness meta-structure for high-efficiency vibration isolation at low frequency

An easily stackable multi-layer quasi-zero-stiffness(ML-QZS)meta-structure is proposed to achieve highly efficient vibration isolation performance at low frequency.First,the distributed shape optimization method is used to design the unit cel,i.e.,the single-layer QZS(SL-QZS)meta-structure.Second,the stiffness feature of the unit cell is investigated and verified through static experiments.Third,the unit cells are stacked one by one along the direction of vibration isolation,and thus the ML-QZS meta-structure is constructed.Fourth,the dynamic modeling of the ML-QZS vibration isolation metastructure is conducted,and the dynamic responses are obtained from the equations of motion,and verified by finite element(FE)simulations.Finally,a prototype of the ML-QZS vibration isolation meta-structure is fabricated by additive manufacturing,and the vibration isolation performance is evaluated experimentally.The results show that the vibration isolation performance substantially enhances when the number of unit cells increases.More importantly,the ML-QZS meta-structure can be easily extended in the direction of vibration isolation when the unit cells are properly stacked.Hence,the ML-FQZS vibration isolation meta-structure should be a fascinating solution for highly efficient vibration isolation performance at low frequency.

The mixing of multi-source fluids in the Wusihe Zn–Pb ore deposit in Sichuan Province, Southwestern China

The Sichuan-Yunnan-Guizhou(SYG)metallogenic province of southwest China is one of the most important Zn-Pb ore zones in China,with^200 Mt ZnPb ores at mean grades of 10 wt.%Zn and 5 wt.%Pb.The source and mechanism of the regional Zn-Pb mineralization remain controversial despite many investigations that have been conducted.The Wusihe Zn-Pb deposit is a representative large-scale Zn-Pb deposit in the northern SYG,which mainly occurs in the Dengying Formation and yields Zn-Pb resources of^3.7 Mt.In this paper,Zn and S isotopes,and Fe and Cd contents of sphalerite from the Wusihe deposit were investigated in an attempt to constrain the controls on Zn and S isotopic variations,the potential sources of ore-forming components,and the possible mineralization mechanisms.Both theδ66Zn andδ34S values in sphalerite from the Wusihe deposit increase systematically from the bottom to the top of the strata-bound orebodies.Such spatial evolution inδ66Zn andδ34S values of sphalerite can be attributed to isotopic Rayleigh fractionation during sphalerite precipitation with temperature variations.The strong correlations between the Zn-S isotopic compositions and Fe-Cd concentrations in sphalerite suggest that their variations were dominated by a similar mechanism.However,the Rayleigh fractionation mechanism cannot explain the spatial variations of Fe and Cd concentrations of sphalerite in this deposit.It is noted that the bottom and top sphalerites from the strata-bound orebodies document contrasting Zn and S isotopic compositions which correspond to the Zn and S isotopic characteristics of basement rocks and host rocks,respectively.Therefore,the mixing of two-source fluids with distinct Zn-S isotopic signatures was responsible for the spatial variations of Zn-S isotopic compositions of sphalerite from the Wusihe deposit.The fluids from basement rocks are characterized by relatively lighter Zn(~0.2‰)and S(~5‰)isotopic compositions while the fluids from host rocks are marked by relatively heavier Zn(~0.6‰)and S(~15‰)isotopic compositions.

Enrichment of putative human epidermal stem cells based on cell size and collagen type IV adhesiveness

The enrichment and identification of human epidermal stem cells （EpSCs） are of paramount importance for both basic research and clinical application. Although several approaches for the enrichment of EpSCs have been established, enriching a pure population of viable EpSCs is still a challenging task. An improved approach is worth developing to enhance the purity and viability of EpSCs. Here we report that cell size combined with collagen type IV adhesiveness can be used in an improved approach to enrich pure and viable human EpSCs. We separated the rap- idly adherent keratinocytes into three populations that range in size from 5-7 μm （population A）, to 7-9 μm （population B）, to ≥9μm （population C） in diameter, and found that human putative EpSCs could be further enriched in population A with the smallest size. Among the three populations, population A displayed the highest density of plintegrin receptor, contained the highest percentage of cells in G0/G1 phase, showed the highest nucleus to cytoplasm ratio, and possessed the highest colony formation efficiency （CFE）. When injected into murine blastocysts, these cells participated in multi-tissue formation. More significantly, compared with a previous approach that sorted putative EpSCs according to pl-integrin antibody staining, the viability of the EpSCs enriched by the improved approach was significantly enhanced. Our results provide a putative strategy for the enrichment of human EpSCs, and encourage further study into the role of cell size in stem cell biology.

A brief review of metamaterials for opening low-frequency band gaps

Metamaterials are an emerging type of man-made material capable of obtaining some extraordinary properties that cannot be realized by naturally occurring materials.Due to tremendous application foregrounds in wave manipulations,metamaterials have gained more and more attraction.Especially,developing research interest of low-frequency vibration attenuation using metamaterials has emerged in the past decades.To better understand the fundamental principle of opening low-frequency(below 100 Hz)band gaps,a general view on the existing literature related to low-frequency band gaps is presented.In this review,some methods for fulfilling low-frequency band gaps are firstly categorized and detailed,and then several strategies for tuning the low-frequency band gaps are summarized.Finally,the potential applications of this type of metamaterial are briefly listed.This review is expected to provide some inspirations for realizing and tuning the low-frequency band gaps by means of summarizing the related literature.

Identifying the leucogranites in the Ailaoshan-Red River shear zone:Constraints on the timing of the southeastward expansion of the Tibetan Plateau

The uplift of the Tibetan Plateau significantly affected the global climate system.However,the timing of its uplift and the formation of its vast expanse are poorly understood.The occurrence of two types of leucogranites(the two-mica leucogranites and garnet-bearing leucogranites) identified in the Ailaoshan-Red River(ASRR) shear zone suggests an extension event in the southeastern Tibetan Plateau.The age of these leucogranites could be used to constrain the timing of uplift and southeastward expansion of the plateau.Petrography,geochronology and geochemistry investigations,including Sr-Nd isotope analysis,were conducted on the two-mica leucogranites and garnet-bearing leucogranites from the ASRR shear zone.LA-ICP-MS zircon U-Pb dating indicates that these rocks were emplaced at ~27 Ma,implying that the Tibetan Plateau had already achieved maximum uplift prior to the late Oligocene.It subsequently started to expand southeastward as a result of crustal flow.Compared to classic metapelite-derived leucogranites from Himalaya,the two-mica leucogranites show high K_2 O/Na_2 O(1.31-1.92),low Rb/Sr,CaO,lower ^(87)Sr/^(86)Sr ratios(0.7089-0.7164) and higher ε_(Nd)(t)(-8.83 to-3.10).This whole-rock geochemical characteristics likely indicates a mixing source origin,composed predominantly of amphibolite with subordinated metapelite,which is also evidenced by ^(87)Sr/^(86)Sr vs.ε_(Nd)(t) diagram.However,The garnetbearing leucogranites with high SiO_2 contents(72.25-74.12 wt.%) have high initial ^(87)Sr/^(86)Sr ratios(0.7332-0.7535) and low ε_(Nd)(t)(-16.36 to 18.98),indicating that they are derived from the source comprised of metapelite and results of fluexed muscovite melting under lower crustal level,which is also evidenced by the Rb-Sr-Ba systematics.These leucogranites formed from partial melting of the thickened lower crust,which resulted in the formation of granitic melt that weakened the crust.The weakened crust aided the left-lateral strikeslip movement of the ASRR shear zone,triggering the escape of the Indochina terrane in the southeastern Tibetan Plateau during the late Oligocene.

Fractional nonlinear energy sinks

The cubic or third-power(TP)nonlinear energy sink(NES)has been proven to be an effective method for vibration suppression,owing to the occurrence of targeted energy transfer(TET).However,TET is unable to be triggered by the low initial energy input,and thus the TP NES would get failed under low-amplitude vibration.To resolve this issue,a new type of NES with fractional nonlinearity,e.g.,one-third-power(OTP)nonlinearity,is proposed.The dynamic behaviors of a linear oscillator(LO)with an OTP NES are investigated numerically,and then both the TET feature and the vibration attenuation performance are evaluated.Moreover,an analogy circuit is established,and the circuit simulations are carried out to verify the design concept of the OTP NES.It is found that the threshold for TET of the OTP NES is two orders of magnitude smaller than that of the TP NES.The parametric analysis shows that a heavier mass or a lower stiffness coefficient of the NES is beneficial to the occurrence of TET in the OTP NES system.Additionally,significant energy transfer is usually accompanied with efficient energy dissipation.Consequently,the OTP NES can realize TET under low initial input energy,which should be a promising approach for micro-vibration suppression.

TRANSIENT THERMAL RESPONSE IN THICK ORTHOTROPIC HOLLOW CYLINDERS WITH FINITE LENGTH:HIGH ORDER SHELL THEORY

The transient thermal response of a thick orthotropic hollow cylinder with finite length is studied by a high order shell theory. The radial and axial displacements are assumed to have quadratic and cubic variations through the thickness, respectively. It is important that the radial stress is approximated by a cubic expansion satisfying the boundary conditions at the inner and outer surfaces, and the corresponding strain should be least-squares compatible with the strain derived from the strain-displacement relation. The equations of motion are derived from the integration of the equilibrium equations of stresses, which are solved by precise integration method （PIM）. Numerical results are.obtained, and compared with FE simulations and dynamic thermo-elasticity solutions, which indicates that the high order shell theory is capable of predicting the transient thermal response of an orthotropic （or isotropic） thick hollow cylinder efficiently, and for the detonation tube of actual pulse detonation engines （PDE） heated continuously, the thermal stresses will become too large to be neglected, which are not like those in the one time experiments with very short time.

List-Serial Pipelined Hardware Architecture for SCL Decoding of Polar Codes

For polar codes,the performance of successive cancellation list(SCL)decoding is capable of approaching that of maximum likelihood decoding.However,the existing hardware architectures for the SCL decoding suffer from high hardware complexity due to calculating L decoding paths simultaneously,which are unfriendly to the devices with limited logical resources,such as field programmable gate arrays(FPGAs).In this paper,we propose a list-serial pipelined hardware architecture with low complexity for the SCL decoding,where the serial calculation and the pipelined operation are elegantly combined to strike a balance between the complexity and the latency.Moreover,we employ only one successive cancellation(SC)decoder core without L×L crossbars,and reduce the number of inputs of the metric sorter from 2L to L+2.Finally,the FPGA implementations show that the hardware resource consumption is significantly reduced with negligible decoding performance loss.

Design of quasi-zero-stiffness elastic diodes for low-frequency nonreciprocity through machine learning

Elastic diodes with nonreciprocity have the potential to enable unidirectional modulation of elastic waves.However,it is a challenge to achieve nonreciprocity at low frequencies(<100 Hz)using existing elastic diodes.This paper proposes a quasizero-stiffness(QZS)elastic diode to resolve such a tough issue and fulfill high-quality low-frequency nonreciprocity.The proposed elastic diode is invented by combining a QZS locally resonant metamaterial with a linear one,where the beneficial nonlinearity of the QZS metamaterial facilitates opening an amplitude-dependent band gap at very low frequencies.Firstly,the dispersion relation of the QZS metamaterial is derived theoretically based on the harmonic balance method(HBM).Then,the transmissibility of the QZS elastic diode in both the forward and backward directions is calculated through theoretical analyses and numerical simulations.Additionally,the influences of system parameters on the low-frequency nonreciprocal effect are discussed.The results indicate that considerable nonreciprocity is observed at a quite low frequency(e.g.,9 Hz),which is achieved by amplitude-dependent local resonance combined with interface reflection.Finally,a machine learning-based design optimization is introduced to evaluate and enhance the nonreciprocal effect of the QZS elastic diode.With the aid of machine learning(ML),the computational cost of predicting nonreciprocal effects during design optimization can be significantly reduced.Through design optimization,the nonreciprocal frequency bandwidth can be broadened while maintaining considerable isolation quality at low frequencies.

Identification and characterization of human hematopoietic mesoderm

The embryonic mesoderm comprises heterogeneous cell subpopulations with distinct lineage biases.It is unclear whether a bias for the human hematopoietic lineage emerges at this early developmental stage.In this study,we integrated single-cell transcriptomic analyses of human mesoderm cells from embryonic stem cells and embryos,enabling us to identify and define the molecular features of human hematopoietic mesoderm(HM)cells biased towards hematopoietic lineages.We discovered that BMP4 plays an essential role in HM specification and can serve as a marker for HM cells.Mechanistically,BMP4 acts as a downstream target of HDAC1,which modulates the expression of BMP4 by deacetylating its enhancer.Inhibition of HDAC significantly enhances HM specification and promotes subsequent hematopoietic cell differentiation.In conclusion,our study identifies human HM cells and describes new mechanisms for human hematopoietic development.

贵阳地区蝉花微生态系统中细菌种群结构与功能

【目的】探索自然生态下蝉花内菌核、菌膜和环境细菌群落结构、功能及其相互关系。【方法】对细菌16S rRNA扩增片段进行高通量测序,分析贵阳市大将山和贵阳森林公园的蝉花内菌核、菌膜及其生境土壤的细菌群落组成、多样性及潜在功能。【结果】蝉花内菌核样本共检测到细菌562个属,菌膜样本521个属,菌际土样本578个属。两地的各组样本细菌群落结构相似,内菌核样本中假单胞菌属Pseudomonas、沙雷氏菌属Serratia占优势地位;菌膜样本中假单胞菌属和氨基杆菌属Aminobacter占优势;土壤样本以未分类的酸杆菌纲Acidobacteria和黄杆菌科Xanthobacteraceae为优势属。Venn图分析显示,菌际土样本包括了菌膜样本的大多数属,内菌核样本拥有较多的特有属,如沃尔巴克氏体属Wolbachia和立克次氏体Rickettsia等。PICRUSt功能预测结果显示,共计24个基因功能家族,主要与物质能量的代谢运输、细胞的行为发生及调控等功能相关。【结论】蝉花及其微生境中细菌具有丰富多样性,它们的潜在功能可能与营养物质的新陈代谢有关,对蝉花的个体生长发育有重要作用。研究结果对蝉花虫草的生态信息数据补充和仿野生栽培具有参考价值。

Re-Os Dating of Galena and Sphalerite from Lead-Zinc Sulfide Deposits in Yunnan Province, SW China

Dating of lead-zinc deposits is of critical importance for better understanding of ore genesis, but has long been a big challenge due to the lack of suitable minerals that can be unequivocally linked to the ore genesis and that can be used for tradition radiometric methods. This kind of deposits have simple mineralogy dominated by galena and sphalerite commonly associated with calcite and other gangue minerals. Both galena and sphalerite have low and high variable Re concentrations and thus Re-Os dating of these minerals have been less promising. In addition, the recovery of Re is extremely low for galena when conventional method was applied, lending additional difficulty in precisely dating galena. In this study, we investigate the recovery of Re using different media for anion exchange separation and reporte a revised preparation method for Re-Os dating of galena and sphalerite. By using the new protocol, two reliable Re-Os isochron ages of galena and sphalerite from the Fule（20.4±3.2 Ma） and Laochang（308±25 Ma） Pb-Zn deposits in Yunnan Province, SW China, are achieved.

A limb-inspired bionic quasi-zero stiffness vibration isolator

Vibration reduction has always been one of hot and important topics in mechanical engineering,especially for the special measurement instrument.In this paper,a novel limb-inspired bionic structure is proposed to generate negative stiffness and design a new quasi-zero stiffness isolator via torsion springs,distinguishing from the existing tension spring structures in the literature.The nonlinear mathematical model of the proposed structure is developed and the corresponding dynamic properties are further investigated by using the Harmonic Balance method and ADAMS verification.To evaluate the vibration isolation performance,typical three-springs quasi-zero stiffness(TS QZS)system is selected to compare with the proposed bionic structure.And the graphical processing unit(GPU)parallel technology is applied to perform necessary two-parameter analyses,providing more insights into the effects of parameters on the transmissibility.It is shown that the proposed structure can show advantages over the typical TS QZS system in a wider vibration isolation range for harmonic excitation case and shorter decay time for the impact excitation case.

Numerical and Experimental Investigations on Tunable Low-frequency Locally Resonant Metamaterials

In this paper,a tunable locally resonant metamaterial is proposed for low-frequency band gaps.The local resonator composed of two pairs of folded slender beams and a proof mass is designed based on the theory of compliant mechanism.The design optimization on geometric parameters is carried out to fulfil the quasi-zero-stiffness property.The locally resonant metamaterial is formed by periodically arranged unit cells,and the transmittance of longitudinal wave is studied through three aspects:numerical predictions,finite element simulations and experimental tests.The variation trends revealed by these three methods match well with one another:the band gap moves to lower frequency and both its depth and width get smaller and smaller with the increase of pre-compression(Δ).The band gap overlays the frequency range of 73.10–92.38 Hz and 16.78–19.49 Hz atΔ=0mm andΔ=10mm,respectively,providing a wide range of tunability.Besides,the ultralow-frequency band gap can be achieved asΔapproaches 10 mm.This study may provide an avenue for achieving the tunable ultralow-frequency locally resonant band gap.

mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration

Hair follicles(HFs)undergo cycles of degeneration(catagen),rest(telogen),and regeneration(anagen)phases.Anagen begins when the hair follicle stem cells(HFSCs)obtain sufficient activation cues to overcome suppressive signals,mainly the BMP pathway,from their niche cells.Here,we unveil that mTOR complex 1(mTORC1)signaling is activated in HFSCs,which coincides with the HFSC activation at the telogen-to-anagen transition.By using both an inducible conditional gene targeting strategy and a pharmacological inhibition method to ablate or inhibit mTOR signaling in adult skin epithelium before anagen initiation,we demonstrate that HFs that cannot respond to mTOR signaling display significantly delayed HFSC activation and extended telogen.Unexpectedly,BMP signaling activity is dramatically prolonged in mTOR signaling-deficient HFs.Through both gain-and loss-of-function studies in vitro,we show that mTORC1 signaling negatively affects BMP signaling,which serves as a main mechanism whereby mTORC1 signaling facilitates HFSC activation.Indeed,in vivo suppression of BMP by its antagonist Noggin rescues the HFSC activation defect in mTORC1-null skin.Our findings reveal a critical role for mTOR signaling in regulating stem cell activation through counterbalancing BMP-mediated repression during hair regeneration.

Modeling and analysis of the friction in a non-linear sliding-mode triboelectric energy harvester

Friction plays a pivotal role in the sliding-mode triboelectric energy harvester(TEH),which not only enables the charge transfer between two dielectrics,but also influences the energy harvesting performance by affecting the dynamic response of the TEH.How to evaluate the effects of the friction on TEHs is important for optimizing TEHs in engineering practices.In order to analyze the effects of the friction on the dynamic response and evaluate the energy harvesting performance ofTEHs,the paper models the friction of a devised non-linear TEH based on the Coulomb friction model and the Macro-slip friction theory.The TEH equips a pair of magnets,rendering a switching between the bistability and the monostability by tuning the distance between two magnets.The dynamic model of the non-linear TEH is established by the extended Hamilton principle.The effects of friction in slidingmode TEH are dissected in detail.The influences of parameters on both the mechanical and electrical responses are also systemically studied to explore an optimal energy harvesting performance in the low-frequency range.This work provides a guideline for designing and accurately analyzing a sliding-mode TEH.

非光滑准零刚度隔振器实验研究

理论上,与传统准零刚度隔振器(QZS)相比,含限位结构的准零刚度隔振器具有更低的位移传递率峰值和更宽的隔振频率范围.但是,目前还没有相关的实验研究证明这一理论结果的正确性.因此,为了研究含限位准零刚度隔振器在实际应用过程中的隔振特性,本文设计制作了相应的结构,并进行了动力学实验.首先,根据赫兹接触理论,建立了含限位结构的准零刚度隔振器(QZS-HCM)动力学模型.然后,对隔振器的结构进行设计和加工,制作了QZS-HCM系统,并对系统进行静力学实验来验证理论结果的正确性.接着,在简谐位移激励下,对QZS-HCM系统进行动力学测试,通过分析系统的位移传递率和时间历程来评价系统的隔振性能.同时,将QZS-HCM系统与传统QZS系统的动力学测试结果进行对比,表明QZS-HCM隔振器在大幅值位移激励下具有更低的位移响应峰值和更宽的隔振频带.