Cutaneous neurofibroma(cNF)is a prevalent clinical manifestation of neurofibromatosis type 1,significantly affecting the well-being and quality of life of the affected individuals.The adoption of reliable and reproduc...Cutaneous neurofibroma(cNF)is a prevalent clinical manifestation of neurofibromatosis type 1,significantly affecting the well-being and quality of life of the affected individuals.The adoption of reliable and reproducible volumetric measurement techniques is essential for precisely evaluating tumor burden and plays a critical role in the development of effective treatments for cNF.This study focuses on widely used volumetric measurement techniques,including vernier calipers,ultrasound,computed tomography,magnetic resonance imaging,and three-dimensional scanning imaging.It outlines the merits and drawbacks of each technique in assessing the cNF load,providing an overview of their current applications and ongoing research advancements in this domain.展开更多
Based on the study of phase angle and wavelength in pBRDF (Polarized bidirectional reflectance distribution function), roujean model was proposed to describe Orient (Polarization phase angle) quantitatively. The Rouje...Based on the study of phase angle and wavelength in pBRDF (Polarized bidirectional reflectance distribution function), roujean model was proposed to describe Orient (Polarization phase angle) quantitatively. The Roujean model was used to quantitatively describe different fruits intensity components (<i><span style="font-family:Verdana;font-size:12px;">F</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;">) and polarization phase angle (Orient), and the simulation results were analyzed and compared using statistical analysis and comparison methods to realize the prediction from the regular model to the outdoor fruit tree canopy to the canopy of outdoor fruit tree canopy random distribution. The experimental results showed that: 1) when the phase angle of jujube was 52.19<span style="white-space:nowrap;">°</span>, 66.51<span style="white-space:nowrap;">°</span></span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">and 88.26<span style="white-space:nowrap;">°</span>, the </span><i><span style="font-family:Verdana;font-size:12px;">R</span></i><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average errors of </span><i><span style="font-family:Verdana;font-size:12px;">F</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;"> parameters described by Roujean model are 0.9982, 0.9963, 0.9912 and 3.80%, 4.17%, 6.40%, respectively;</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">a</span><span style="font-family:Verdana;font-size:12px;">nd the </span><i><span style="font-family:Verdana;font-size:12px;">R</span></i><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average error of Orient parameters described by Roujean model are 0.9056,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">0.9223,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">0.9260 and 6.23%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">3.32%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">8.05%, respectively;It can be seen that roujean model can quantitatively describe the Orient parameter of jujube</span><span style="font-family:Verdana;font-size:12px;">;</span><span style="font-family:Verdana;font-size:12px;">2) When the phase angle of apricot was 70.99<span style="white-space:nowrap;">°</span>, 71.28<span style="white-space:nowrap;">°</span> and 67.91<span style="white-space:nowrap;">°</span>, the </span><i><span style="font-family:Verdana;font-size:12px;">R</span></i><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average errors of </span><i><span style="font-family:Verdana;font-size:12px;">F</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;"> parameters described by Roujean model </span><span style="font-family:Verdana;font-size:12px;">is</span><span style="font-family:Verdana;font-size:12px;"> 0.9862, 0.9823, 0.9792 and 3.40%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">4.82%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">5.19%, respectively;</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">And the R</span><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average error of Orient parameters described by Roujean model are 0.9382, 0.8947, 0.8849 and 7.19%, 9.28%, 9.47%, respectively.</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">Roujean model can also quantitatively describe the Orient parameter of white apricot. In summary, the Roujean model can provide a good quantitative description of </span><i><span style="font-family:Verdana;font-size:12px;">f</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;"> and a good quantitative description of Orient, which in turn can predict the pBRDF parameter for more fruits with different incidence and detection directions.</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">It can correct the influence of angle factor in the nondestructive testing of outdoor fruits.</span>展开更多
Intercropping cereals and legumes is practiced widely in the world for improving yields and economic benefits. Shorter legume crops in intercropping are shaded by taller cereals, substantially reducing legume growth a...Intercropping cereals and legumes is practiced widely in the world for improving yields and economic benefits. Shorter legume crops in intercropping are shaded by taller cereals, substantially reducing legume growth and yield. Reducing shade in intercropping by shortening the plant height of cereals by seedling defoliation has been proposed as a practical approach to increase crop yields and land productivity. A two-year field experiment was conducted to investigate the effect of defoliation of cereal crops at seedling stage on the growth and yield of peanut(Arachis hypogaea L.) intercropped with corn(Zea mays L.) or millet(Setaria italica L.). In comparison with non-defoliation controls, defoliation reduced final plant height by 29 cm on average for corn and 18 cm for millet. Photosynthetically active radiation on peanut in intercropping systems with corn or millet intercropping was respectively 27.0% and 22.8% higher than those in controls, significantly improving the light environment of intercropped peanut. Net photosynthetic rates of peanut were on average 25.5% higher in corn and peanut intercropping and 19.6% higher in millet and peanut intercropping than those in non-defoliation controls. Total biomass of intercropped peanut increased owing to increased root growth. Across two years, yield of peanut intercropped with corn was 27.7% and with millet 32.8% higher than those of controls. Defoliation of cereal crops did not affect corn yield but significantly decreased millet yield by 24.5%. Our results suggest that applying seedling defoliation in intercropped corn could increase peanut yield without compromising corn yield in an intercropping system.展开更多
Environmental,social and governance(ESG)practices are pivotal to global sustainability yet face challenges.Based on the implementation of Golden Tax Project Ⅲ,we find that big data tax administration decreases corpor...Environmental,social and governance(ESG)practices are pivotal to global sustainability yet face challenges.Based on the implementation of Golden Tax Project Ⅲ,we find that big data tax administration decreases corporate ESG performance.Mechanism tests indicate that Golden Tax Project Ⅲ can reduce tax avoidance,cash flow and green innovation,thereby inhibiting ESG through the“taxation effect.”Conversely,the project can reduce agency costs and improve information transparency,thus promoting ESG performance through the“governance effect.”Overall,however,the project inhibits corporate ESG performance.According to further analysis,the negative effect on ESG performance mainly impacts the environmental responsibility(E)element.This paper provides insights relevant to advancing China’s“dual carbon”policy and formulating a“Chinese approach”to global sustainable development.展开更多
Support vector machines(SVMs) are supervised learning models traditionally employed for classification and regression analysis. In classification analysis, a set of training data is chosen, and each instance in the tr...Support vector machines(SVMs) are supervised learning models traditionally employed for classification and regression analysis. In classification analysis, a set of training data is chosen, and each instance in the training data is assigned a categorical class. An SVM then constructs a model based on a separating plane that maximizes the margin between different classes. Despite being one of the most popular classification models because of its strong performance empirically, understanding the knowledge captured in an SVM remains difficult. SVMs are typically applied in a black-box manner where the details of parameter tuning, training, and even the final constructed model are hidden from the users. This is natural since these details are often complex and difficult to understand without proper visualization tools. However, such an approach often brings about various problems including trial-and-error tuning and suspicious users who are forced to trust these models blindly.The contribution of this paper is a visual analysis approach for building SVMs in an open-box manner.Our goal is to improve an analyst's understanding of the SVM modeling process through a suite of visualization techniques that allow users to have full interactive visual control over the entire SVM training process.Our visual exploration tools have been developed to enable intuitive parameter tuning, training datamanipulation, and rule extraction as part of the SVM training process. To demonstrate the efficacy of our approach, we conduct a case study using a real-world robot control dataset.展开更多
The fabrication of small-scale electronics usually involves the integration of different functional materials.The electronic states at the nanoscale interface plays an important role in the device performance and the ...The fabrication of small-scale electronics usually involves the integration of different functional materials.The electronic states at the nanoscale interface plays an important role in the device performance and the exotic interface physics.Photoemission spectroscopy is a powerful technique to probe electronic structures of valence band.However,this is a surface-sensitive technique that is usually considered not suitable for the probing of buried interface states,due to the limitation of electron-mean-free path.This article reviews several approaches that have been used to extend the surface-sensitive techniques to investigate the buried interface states,which include hard X-ray photoemission spectroscopy,resonant soft X-ray angle-resolved photoemission spectroscopy and thickness-dependent photoemission spectroscopy.Especially,a quantitative modeling method is introduced to extraa the buried interface states based on the film thickness-dependent photoemission spectra obtained from an integrated experimental system equipped with in-situ growth and photoemission techniques.This quantitative modeling method shall be helpful to further understand the interfacial electronic states between functional materials and determine the interface layers.展开更多
目的比较早期腹腔镜胆囊切除术(LC)与经皮肝穿刺胆道引流术(PTCD)续贯LC治疗急性胆囊炎对患者肝功能及预后的影响。方法选取2020年6月至2022年6月我院治疗的92例急性胆囊炎患者,采用随机数字表将患者分为观察组和对照组,每组各46例,对...目的比较早期腹腔镜胆囊切除术(LC)与经皮肝穿刺胆道引流术(PTCD)续贯LC治疗急性胆囊炎对患者肝功能及预后的影响。方法选取2020年6月至2022年6月我院治疗的92例急性胆囊炎患者,采用随机数字表将患者分为观察组和对照组,每组各46例,对照组实施早期LC术,观察组实施PTCD续贯LC术。采用SPSS 22.0软件分析数据,围手术期指标、疼痛视觉模拟(VAS)评分、肝功能指标及应激反应指标等计量资料以(均数±标准差)表示,组间比较采用独立样本t检验,同组手术前后比较采用配对样本t检验;术后并发症等计数资料以[例(%)]表示,行χ^(2)检验。P<0.05为差异有统计学意义。结果观察组患者LC手术时间、肛门排气时间、留置引流管时间、术中出血量均小于对照组(P<0.05);观察组患者术后1 d、3 d VAS评分,术后7 d 谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素(TBIL)、直接胆红素(DBIL)、白细胞计数(WBC)、促肾上腺皮质激素(ACTH)、皮质醇(Cor)及并发症总发生率均低于对照组(P<0.05)。结论PTCD续贯LC治疗急性胆囊炎可减轻机体应激反应,促进肝功能恢复,减少并发症的发生。展开更多
Myocardial regeneration has been considered a promising option for the treatment of adult myocardial injuries.Previously,a chick early amniotic fluid(ceAF)preparation was shown to contain growth-related factors that p...Myocardial regeneration has been considered a promising option for the treatment of adult myocardial injuries.Previously,a chick early amniotic fluid(ceAF)preparation was shown to contain growth-related factors that pro-moted embryonic growth and cellular proliferation,though the nature of the components within ceAF were not fully defined.Here we tested whether this ceAF preparation is similarly effective in the promotion of myocardial regen-eration,which could provide an alternative therapeutic for intervening myocardial injury.In this study,a myocardial ischemic injury model was established in adult mice and pigs by multiple research entities,and we were able to show that ceAF can efficiently rescue damaged cardiac tissues and markedly improve cardiac function in both experimental models through intravenous administration.ceAF administration increased cell proliferation and improved angio-genesis,likely via down-regulation of Hippo-YAP signaling.Our data suggest that ceAF administration can effectively rescue ischemic heart injury,providing the key functional information for the further development of ceAF for use in attenuating myocardial injury.展开更多
The advanced telecom technologies and massive volumes of intelligent mobile phone users have yielded a huge amount of real-time data of people’s all-in-one telecommunication records,which we call telco big data.With ...The advanced telecom technologies and massive volumes of intelligent mobile phone users have yielded a huge amount of real-time data of people’s all-in-one telecommunication records,which we call telco big data.With telco data and the domain knowledge of an urban city,we are now able to analyze the movement and contact patterns of humans in an unprecedented scale.Flow map is widely used to display the movements of humans from one single source to multiple destinations by representing locations as nodes and movements as edges.However,it fails the task of visualizing both movement and contact data.In addition,analysts often need to compare and examine the patterns side by side,and do various quantitative analysis.In this work,we propose a novel spatio-temporal flow map layout to visualize when and where people from different locations move into the same places and make contact.We also propose integrating the spatiotemporal flow maps into existing spatiotemporal visualization techniques to form a suite of techniques for visualizing the movement and contact patterns.We report a potential application the proposed techniques can be applied to.The results show that our design and techniques properly unveil hidden information,while analysis can be achieved efficiently.展开更多
Traditional Chinese Medicine(TCM)has played crucial roles in treating COVID-19 in China.But its effectiveness has not yet been widely realized/recognized over the world.We performed a systematic review and meta-analys...Traditional Chinese Medicine(TCM)has played crucial roles in treating COVID-19 in China.But its effectiveness has not yet been widely realized/recognized over the world.We performed a systematic review and meta-analysis to investigate the clinical efficacy of TCM medicine in the treatment for COVID-19.We obtained the data of COVID-19 and traditional Chinese medicine from PubMed,MEDLINE,Web of Science and other databases,and searched from January 1,2020 to January 26,2022 to determine the randomized controlled trials(RCTs)without language restrictions.The review includes 26 randomized clinical trials including 2981 patients.The treatment of COVID-19 by TCM combined with conventional treatment is more effective than by pure conventional treatment in many aspects,including increasing of the effective rate[OR=2.47,95%CI(1.85,3.30),P<0.00001],fever disappearance rate[OR=3.68,95%CI(1.95,6.96),P<0.0001],fatigue disappearance rate[OR=3.15,95%CI(1.60,6.21),P=0.0009],cough disappearance rate[OR=2.89,95%CI(1.84,4.54),P<0.00001],expectoration disappearance rate[OR=5.94,95%CI(1.98,17.84),P=0.001],disappearance rate of shortness of breath[OR=2.57,95%CI(1.13,5.80),P=0.02],improvement rate of CT image[OR=2.43,95%CI(1.86,3.16),P<0.00001],and reduction of the hospitalization time[MD=3.16,95%CI(3.75,2.56),P<0.00001],and deterioration rate[OR=0.49,95%CI(0.29,0.83),P=0.007].The findings of this meta-analysis suggest that TCM can effectively relieve symptoms,boosted patients' recovery,cut the rate of patients developing into severe conditions,and reduce the deterioration rate.展开更多
文摘Cutaneous neurofibroma(cNF)is a prevalent clinical manifestation of neurofibromatosis type 1,significantly affecting the well-being and quality of life of the affected individuals.The adoption of reliable and reproducible volumetric measurement techniques is essential for precisely evaluating tumor burden and plays a critical role in the development of effective treatments for cNF.This study focuses on widely used volumetric measurement techniques,including vernier calipers,ultrasound,computed tomography,magnetic resonance imaging,and three-dimensional scanning imaging.It outlines the merits and drawbacks of each technique in assessing the cNF load,providing an overview of their current applications and ongoing research advancements in this domain.
文摘Based on the study of phase angle and wavelength in pBRDF (Polarized bidirectional reflectance distribution function), roujean model was proposed to describe Orient (Polarization phase angle) quantitatively. The Roujean model was used to quantitatively describe different fruits intensity components (<i><span style="font-family:Verdana;font-size:12px;">F</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;">) and polarization phase angle (Orient), and the simulation results were analyzed and compared using statistical analysis and comparison methods to realize the prediction from the regular model to the outdoor fruit tree canopy to the canopy of outdoor fruit tree canopy random distribution. The experimental results showed that: 1) when the phase angle of jujube was 52.19<span style="white-space:nowrap;">°</span>, 66.51<span style="white-space:nowrap;">°</span></span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">and 88.26<span style="white-space:nowrap;">°</span>, the </span><i><span style="font-family:Verdana;font-size:12px;">R</span></i><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average errors of </span><i><span style="font-family:Verdana;font-size:12px;">F</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;"> parameters described by Roujean model are 0.9982, 0.9963, 0.9912 and 3.80%, 4.17%, 6.40%, respectively;</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">a</span><span style="font-family:Verdana;font-size:12px;">nd the </span><i><span style="font-family:Verdana;font-size:12px;">R</span></i><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average error of Orient parameters described by Roujean model are 0.9056,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">0.9223,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">0.9260 and 6.23%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">3.32%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">8.05%, respectively;It can be seen that roujean model can quantitatively describe the Orient parameter of jujube</span><span style="font-family:Verdana;font-size:12px;">;</span><span style="font-family:Verdana;font-size:12px;">2) When the phase angle of apricot was 70.99<span style="white-space:nowrap;">°</span>, 71.28<span style="white-space:nowrap;">°</span> and 67.91<span style="white-space:nowrap;">°</span>, the </span><i><span style="font-family:Verdana;font-size:12px;">R</span></i><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average errors of </span><i><span style="font-family:Verdana;font-size:12px;">F</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;"> parameters described by Roujean model </span><span style="font-family:Verdana;font-size:12px;">is</span><span style="font-family:Verdana;font-size:12px;"> 0.9862, 0.9823, 0.9792 and 3.40%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">4.82%,</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">5.19%, respectively;</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">And the R</span><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and average error of Orient parameters described by Roujean model are 0.9382, 0.8947, 0.8849 and 7.19%, 9.28%, 9.47%, respectively.</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">Roujean model can also quantitatively describe the Orient parameter of white apricot. In summary, the Roujean model can provide a good quantitative description of </span><i><span style="font-family:Verdana;font-size:12px;">f</span></i><sub><span style="font-family:Verdana;font-size:12px;vertical-align:sub;">00</span></sub><span style="font-family:Verdana;font-size:12px;"> and a good quantitative description of Orient, which in turn can predict the pBRDF parameter for more fruits with different incidence and detection directions.</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">It can correct the influence of angle factor in the nondestructive testing of outdoor fruits.</span>
基金funded by National Key Research and Development Program of China(2016YFD0300202)China Agriculture Research System(CARS-08-G09)+1 种基金National Natural Science Foundation of China(32071551)Liao Ning Revitalization Talents Program(XLYC1907089)。
文摘Intercropping cereals and legumes is practiced widely in the world for improving yields and economic benefits. Shorter legume crops in intercropping are shaded by taller cereals, substantially reducing legume growth and yield. Reducing shade in intercropping by shortening the plant height of cereals by seedling defoliation has been proposed as a practical approach to increase crop yields and land productivity. A two-year field experiment was conducted to investigate the effect of defoliation of cereal crops at seedling stage on the growth and yield of peanut(Arachis hypogaea L.) intercropped with corn(Zea mays L.) or millet(Setaria italica L.). In comparison with non-defoliation controls, defoliation reduced final plant height by 29 cm on average for corn and 18 cm for millet. Photosynthetically active radiation on peanut in intercropping systems with corn or millet intercropping was respectively 27.0% and 22.8% higher than those in controls, significantly improving the light environment of intercropped peanut. Net photosynthetic rates of peanut were on average 25.5% higher in corn and peanut intercropping and 19.6% higher in millet and peanut intercropping than those in non-defoliation controls. Total biomass of intercropped peanut increased owing to increased root growth. Across two years, yield of peanut intercropped with corn was 27.7% and with millet 32.8% higher than those of controls. Defoliation of cereal crops did not affect corn yield but significantly decreased millet yield by 24.5%. Our results suggest that applying seedling defoliation in intercropped corn could increase peanut yield without compromising corn yield in an intercropping system.
基金funded by a grant from the National Social Science Foundation of China(No.23BGL095)Professional English language editing support provided by AsiaEdit(asiaedit.com).
文摘Environmental,social and governance(ESG)practices are pivotal to global sustainability yet face challenges.Based on the implementation of Golden Tax Project Ⅲ,we find that big data tax administration decreases corporate ESG performance.Mechanism tests indicate that Golden Tax Project Ⅲ can reduce tax avoidance,cash flow and green innovation,thereby inhibiting ESG through the“taxation effect.”Conversely,the project can reduce agency costs and improve information transparency,thus promoting ESG performance through the“governance effect.”Overall,however,the project inhibits corporate ESG performance.According to further analysis,the negative effect on ESG performance mainly impacts the environmental responsibility(E)element.This paper provides insights relevant to advancing China’s“dual carbon”policy and formulating a“Chinese approach”to global sustainable development.
基金supported in part by the National Basic Research Program of China (973 Program, No. 2015CB352503)the Major Program ofNational Natural Science Foundation of China (No. 61232012)the National Natural Science Foundation of China (No. 61422211)
文摘Support vector machines(SVMs) are supervised learning models traditionally employed for classification and regression analysis. In classification analysis, a set of training data is chosen, and each instance in the training data is assigned a categorical class. An SVM then constructs a model based on a separating plane that maximizes the margin between different classes. Despite being one of the most popular classification models because of its strong performance empirically, understanding the knowledge captured in an SVM remains difficult. SVMs are typically applied in a black-box manner where the details of parameter tuning, training, and even the final constructed model are hidden from the users. This is natural since these details are often complex and difficult to understand without proper visualization tools. However, such an approach often brings about various problems including trial-and-error tuning and suspicious users who are forced to trust these models blindly.The contribution of this paper is a visual analysis approach for building SVMs in an open-box manner.Our goal is to improve an analyst's understanding of the SVM modeling process through a suite of visualization techniques that allow users to have full interactive visual control over the entire SVM training process.Our visual exploration tools have been developed to enable intuitive parameter tuning, training datamanipulation, and rule extraction as part of the SVM training process. To demonstrate the efficacy of our approach, we conduct a case study using a real-world robot control dataset.
基金the National Natural Science Foundation of China(Grant No.U1332105)by the Xiamen University Malaysia Research Fund(Grant no.XMUMRF/2019-C4/IORI/0002).
文摘The fabrication of small-scale electronics usually involves the integration of different functional materials.The electronic states at the nanoscale interface plays an important role in the device performance and the exotic interface physics.Photoemission spectroscopy is a powerful technique to probe electronic structures of valence band.However,this is a surface-sensitive technique that is usually considered not suitable for the probing of buried interface states,due to the limitation of electron-mean-free path.This article reviews several approaches that have been used to extend the surface-sensitive techniques to investigate the buried interface states,which include hard X-ray photoemission spectroscopy,resonant soft X-ray angle-resolved photoemission spectroscopy and thickness-dependent photoemission spectroscopy.Especially,a quantitative modeling method is introduced to extraa the buried interface states based on the film thickness-dependent photoemission spectra obtained from an integrated experimental system equipped with in-situ growth and photoemission techniques.This quantitative modeling method shall be helpful to further understand the interfacial electronic states between functional materials and determine the interface layers.
文摘目的比较早期腹腔镜胆囊切除术(LC)与经皮肝穿刺胆道引流术(PTCD)续贯LC治疗急性胆囊炎对患者肝功能及预后的影响。方法选取2020年6月至2022年6月我院治疗的92例急性胆囊炎患者,采用随机数字表将患者分为观察组和对照组,每组各46例,对照组实施早期LC术,观察组实施PTCD续贯LC术。采用SPSS 22.0软件分析数据,围手术期指标、疼痛视觉模拟(VAS)评分、肝功能指标及应激反应指标等计量资料以(均数±标准差)表示,组间比较采用独立样本t检验,同组手术前后比较采用配对样本t检验;术后并发症等计数资料以[例(%)]表示,行χ^(2)检验。P<0.05为差异有统计学意义。结果观察组患者LC手术时间、肛门排气时间、留置引流管时间、术中出血量均小于对照组(P<0.05);观察组患者术后1 d、3 d VAS评分,术后7 d 谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素(TBIL)、直接胆红素(DBIL)、白细胞计数(WBC)、促肾上腺皮质激素(ACTH)、皮质醇(Cor)及并发症总发生率均低于对照组(P<0.05)。结论PTCD续贯LC治疗急性胆囊炎可减轻机体应激反应,促进肝功能恢复,减少并发症的发生。
基金This work was supported by ZheJiang HygeianCells Biomedical Co.Ltd.,Hangzhou,Zhejiang,310019,China.
文摘Myocardial regeneration has been considered a promising option for the treatment of adult myocardial injuries.Previously,a chick early amniotic fluid(ceAF)preparation was shown to contain growth-related factors that pro-moted embryonic growth and cellular proliferation,though the nature of the components within ceAF were not fully defined.Here we tested whether this ceAF preparation is similarly effective in the promotion of myocardial regen-eration,which could provide an alternative therapeutic for intervening myocardial injury.In this study,a myocardial ischemic injury model was established in adult mice and pigs by multiple research entities,and we were able to show that ceAF can efficiently rescue damaged cardiac tissues and markedly improve cardiac function in both experimental models through intravenous administration.ceAF administration increased cell proliferation and improved angio-genesis,likely via down-regulation of Hippo-YAP signaling.Our data suggest that ceAF administration can effectively rescue ischemic heart injury,providing the key functional information for the further development of ceAF for use in attenuating myocardial injury.
基金This project is partially funded by a grant(Ref:YBCB2009041-44)Huawei Technologies Noah’s Ark Lab and also grant HK RGC GRF 16241916.
文摘The advanced telecom technologies and massive volumes of intelligent mobile phone users have yielded a huge amount of real-time data of people’s all-in-one telecommunication records,which we call telco big data.With telco data and the domain knowledge of an urban city,we are now able to analyze the movement and contact patterns of humans in an unprecedented scale.Flow map is widely used to display the movements of humans from one single source to multiple destinations by representing locations as nodes and movements as edges.However,it fails the task of visualizing both movement and contact data.In addition,analysts often need to compare and examine the patterns side by side,and do various quantitative analysis.In this work,we propose a novel spatio-temporal flow map layout to visualize when and where people from different locations move into the same places and make contact.We also propose integrating the spatiotemporal flow maps into existing spatiotemporal visualization techniques to form a suite of techniques for visualizing the movement and contact patterns.We report a potential application the proposed techniques can be applied to.The results show that our design and techniques properly unveil hidden information,while analysis can be achieved efficiently.
基金the National Natural Science Foundation of China(Grant No.11932017,11772055,11532009,and 11521062).
文摘Traditional Chinese Medicine(TCM)has played crucial roles in treating COVID-19 in China.But its effectiveness has not yet been widely realized/recognized over the world.We performed a systematic review and meta-analysis to investigate the clinical efficacy of TCM medicine in the treatment for COVID-19.We obtained the data of COVID-19 and traditional Chinese medicine from PubMed,MEDLINE,Web of Science and other databases,and searched from January 1,2020 to January 26,2022 to determine the randomized controlled trials(RCTs)without language restrictions.The review includes 26 randomized clinical trials including 2981 patients.The treatment of COVID-19 by TCM combined with conventional treatment is more effective than by pure conventional treatment in many aspects,including increasing of the effective rate[OR=2.47,95%CI(1.85,3.30),P<0.00001],fever disappearance rate[OR=3.68,95%CI(1.95,6.96),P<0.0001],fatigue disappearance rate[OR=3.15,95%CI(1.60,6.21),P=0.0009],cough disappearance rate[OR=2.89,95%CI(1.84,4.54),P<0.00001],expectoration disappearance rate[OR=5.94,95%CI(1.98,17.84),P=0.001],disappearance rate of shortness of breath[OR=2.57,95%CI(1.13,5.80),P=0.02],improvement rate of CT image[OR=2.43,95%CI(1.86,3.16),P<0.00001],and reduction of the hospitalization time[MD=3.16,95%CI(3.75,2.56),P<0.00001],and deterioration rate[OR=0.49,95%CI(0.29,0.83),P=0.007].The findings of this meta-analysis suggest that TCM can effectively relieve symptoms,boosted patients' recovery,cut the rate of patients developing into severe conditions,and reduce the deterioration rate.