Antimicrobial resistance (AMR) has been declared a major threat to global health, with the potential to reverse advances in treating disease, and impeding other global pri-orities including human development. The urge...Antimicrobial resistance (AMR) has been declared a major threat to global health, with the potential to reverse advances in treating disease, and impeding other global pri-orities including human development. The urgent menace of AMR has been recognized by the World Health Organi-sation Global Action Plan in 2015 [1], the 2016 United Nations General Assembly unanimous commitment to tackle AMR [2], and the Association of Southeast Asian Nations (ASEAN) 2017 declaration on AMR (3)AMR has been highlighted as a major health and economic challenge, with the consequences of failing to meet that challenge falling upon our children and grandchildren. Not only will children bear the burden of rising AMR, they are especially at risk now due to a number of factors. In many studies, children and the elderly are the highest consumers of antimicrobi-als (4)In addition, frequently inappropriate doses in chil-dren mean that they are receiving sub-therapeutic doses, maximizing the chance of encouraging resistant organ-isms to flourish. The normal behaviour of early childhood also encourages the spread of resistant organisms between children. Finally, their lifetime risk of exposure to resistant organisms is higher than adults.展开更多
Preface The rise of antimicrobial resistance (AMR) is recognised as a major threat to global health. The United Nations' Sustain-able Development Goals (SDG) do not explicitly address AMR, but many of the targets ...Preface The rise of antimicrobial resistance (AMR) is recognised as a major threat to global health. The United Nations' Sustain-able Development Goals (SDG) do not explicitly address AMR, but many of the targets within the goals depend on effective therapy for infectious diseases. Notably, these include targets 3.1, 3.2, 3.3, and 3.8, relating to the reduc-tion of early life mortality, eradicating ongoing epidemics including AIDS, tuberculosis and malaria, and achieving universal health coverage, as well as targets relating to pov-erty, malnourishment, and education (1)The World Health Organization (WHO) recognised the outstanding importance of AMR by passing a Global Action Plan in 2015 and declar-ing AMR a global priority (2)However, the WHO Global Action Plan on AMR mentions children only twice and to date includes no specific objectives or action points focusing on child health.展开更多
Coronavirus disease 2019(COVID-19)remains a global epidemic.As of August 18,2021,the number of reported cases has exceeded 207 million globally,with more than 4.3 million deaths.COVID-19 has brought devastating losses...Coronavirus disease 2019(COVID-19)remains a global epidemic.As of August 18,2021,the number of reported cases has exceeded 207 million globally,with more than 4.3 million deaths.COVID-19 has brought devastating losses to human society.The overall crude mortality rate is 1-3%.Although pediatric deaths from COVID-19 are rare,they do occur,as over 9,000 children have died from COVID-19 globally to date[1].With the gradual and broad application of COVID-19 vaccines around the world,the rising proportion of cases among children and unvaccinated young adults demands attention.According to World Health Organization surveillance data.展开更多
The World Health Organization(WHO)announced COVID-19 as a global pandemic in March of 2020[1].The COVID-19 pandemic may persist for a long period of time.Global prevention and control becomes a complex and challenging...The World Health Organization(WHO)announced COVID-19 as a global pandemic in March of 2020[1].The COVID-19 pandemic may persist for a long period of time.Global prevention and control becomes a complex and challenging task,and such efforts should be sustained.Although general measures,such as social distancing,face masks,respiratory hygiene and hand sanitization,will bear fruits for decreasing spread of other respiratory illnesses including influenza,the specific prevention through vaccination is a key focus especially in the upcoming winter and spring seasons[2].展开更多
文摘Antimicrobial resistance (AMR) has been declared a major threat to global health, with the potential to reverse advances in treating disease, and impeding other global pri-orities including human development. The urgent menace of AMR has been recognized by the World Health Organi-sation Global Action Plan in 2015 [1], the 2016 United Nations General Assembly unanimous commitment to tackle AMR [2], and the Association of Southeast Asian Nations (ASEAN) 2017 declaration on AMR (3)AMR has been highlighted as a major health and economic challenge, with the consequences of failing to meet that challenge falling upon our children and grandchildren. Not only will children bear the burden of rising AMR, they are especially at risk now due to a number of factors. In many studies, children and the elderly are the highest consumers of antimicrobi-als (4)In addition, frequently inappropriate doses in chil-dren mean that they are receiving sub-therapeutic doses, maximizing the chance of encouraging resistant organ-isms to flourish. The normal behaviour of early childhood also encourages the spread of resistant organisms between children. Finally, their lifetime risk of exposure to resistant organisms is higher than adults.
文摘Preface The rise of antimicrobial resistance (AMR) is recognised as a major threat to global health. The United Nations' Sustain-able Development Goals (SDG) do not explicitly address AMR, but many of the targets within the goals depend on effective therapy for infectious diseases. Notably, these include targets 3.1, 3.2, 3.3, and 3.8, relating to the reduc-tion of early life mortality, eradicating ongoing epidemics including AIDS, tuberculosis and malaria, and achieving universal health coverage, as well as targets relating to pov-erty, malnourishment, and education (1)The World Health Organization (WHO) recognised the outstanding importance of AMR by passing a Global Action Plan in 2015 and declar-ing AMR a global priority (2)However, the WHO Global Action Plan on AMR mentions children only twice and to date includes no specific objectives or action points focusing on child health.
文摘Coronavirus disease 2019(COVID-19)remains a global epidemic.As of August 18,2021,the number of reported cases has exceeded 207 million globally,with more than 4.3 million deaths.COVID-19 has brought devastating losses to human society.The overall crude mortality rate is 1-3%.Although pediatric deaths from COVID-19 are rare,they do occur,as over 9,000 children have died from COVID-19 globally to date[1].With the gradual and broad application of COVID-19 vaccines around the world,the rising proportion of cases among children and unvaccinated young adults demands attention.According to World Health Organization surveillance data.
文摘The World Health Organization(WHO)announced COVID-19 as a global pandemic in March of 2020[1].The COVID-19 pandemic may persist for a long period of time.Global prevention and control becomes a complex and challenging task,and such efforts should be sustained.Although general measures,such as social distancing,face masks,respiratory hygiene and hand sanitization,will bear fruits for decreasing spread of other respiratory illnesses including influenza,the specific prevention through vaccination is a key focus especially in the upcoming winter and spring seasons[2].
