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Impact of Sedation Protocols on Elderly Patients Undergoing Mechanical Ventilation and Off-Line Weaning
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作者 Yihui Li Yamin Yuan +1 位作者 jinquan zhou Li Ma 《Journal of Clinical and Nursing Research》 2024年第4期322-333,共12页
The proportion of elderly patients in intensive care is increasing, and a significant proportion of them require mechanical ventilation. How to implement safe and effective mechanical ventilation for elderly patients,... The proportion of elderly patients in intensive care is increasing, and a significant proportion of them require mechanical ventilation. How to implement safe and effective mechanical ventilation for elderly patients, and when appropriate off-line is an important issue in the field of critical care medicine. Appropriate sedation can improve patient outcomes, but excessive sedation may lead to prolonged mechanical ventilation and increase the risk of complications. Elderly patients should be closely monitored and evaluated on an individual basis while offline, and the sedation regimen should be dynamically adjusted. This requires the healthcare team to consider the patient’s sedation needs, disease status, and pharmacodynamics and pharmacokinetics of the drug to arrive at the best strategy. Although the current research has provided valuable insights and strategies for sedation and off-line management, there are still many problems to be further explored and solved. 展开更多
关键词 Elderly patients Mechanical ventilation Off-line strategy Sedation treatment
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The Performance of Extracorporeal Membrane Oxygenation in Various Viral Pneumonia Pandemics: A Meta-Analysis and Systematic Review
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作者 Yihui Li Yamin Yuan +1 位作者 jinquan zhou Li Ma 《Journal of Clinical and Nursing Research》 2024年第4期399-410,共12页
Objective: To compare the effects of extracorporeal membrane oxygenation (ECMO) and routine mechanical ventilation on mortality and the risk of associated adverse events in patients with severe viral pneumonia. Method... Objective: To compare the effects of extracorporeal membrane oxygenation (ECMO) and routine mechanical ventilation on mortality and the risk of associated adverse events in patients with severe viral pneumonia. Methods: PubMed, the Cochrane Library, Embase, Web of Science, and other databases were searched to collect case-control or cohort studies on prognoses associated with ECMO treatment for viral pneumonia. Search terms included extracorporeal membrane oxygenation, ECMO, viral pneumonia, COVID-19, influenza, MERS, and others. According to the PICOS principle, two evaluators independently screened the literature, extracted the data, cross-checked the data, and extracted the data again. Two researchers evaluated the risk of bias in the included studies according to the Newcastle-Ottawa Scale (NOS) and cross-checked the results. Meta-analysis was performed using RevMan 5.3 software. Results: Nine studies were included for analysis, encompassing a total of 4,330 patients, which were categorized into ECMO and CMV groups. There were no significant differences between the two groups in most baseline data;however, the ECMO group had a lower oxygenation index, and some studies reported higher SOFA scores in the ECMO group compared to the CMV group. There was no significant difference in in-hospital mortality between the two groups. The length of ICU stay, total hospital stay, and total mechanical ventilation time were longer in the ECMO group than in the CMV group. In terms of adverse events, there was no significant difference in the occurrence of kidney injury between the two groups. Bleeding events were reported in two studies, with more bleeding events occurring in the ECMO group. According to the subgroup analysis of different virus types, there were no statistical differences in the above aspects among patients with swine flu, novel coronavirus, and MERS. Conclusion: ECMO has a certain degree of positive significance in the treatment of severe viral pneumonia, but there is no significant difference in the treatment outcome of ECMO across different epidemic periods. The timing of ECMO treatment, patient management, and withdrawal evaluation still need further research. 展开更多
关键词 Extracorporeal membrane oxygenation Viral pneumonia pandemic META-ANALYSIS
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组织支持感、工作满意度与离职意愿:工作家庭冲突的中介机制 被引量:1
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作者 周金泉 何刚 《南大商学评论》 CSSCI 2018年第2期159-175,共17页
澳门女性庄荷比例已经超过男性庄荷,使得工作家庭平衡问题更加突出。本文以澳门女性博彩庄荷为研究对象,探讨组织支持感、工作家庭冲突、工作满意度及离职意愿间的相互关系。通过413份问卷,调查澳门6家博彩企业全职娱乐场女性庄荷,经分... 澳门女性庄荷比例已经超过男性庄荷,使得工作家庭平衡问题更加突出。本文以澳门女性博彩庄荷为研究对象,探讨组织支持感、工作家庭冲突、工作满意度及离职意愿间的相互关系。通过413份问卷,调查澳门6家博彩企业全职娱乐场女性庄荷,经分析得出结论如下:对于澳门女性博彩庄荷,工作家庭冲突部分中介于组织支持感与工作满意度,并且工作家庭冲突对组织支持感与离职意愿存在完全的中介效果。最后,本文讨论了对澳门博彩业管理实践的启示,以及未来的研究方向。 展开更多
关键词 组织支持感 工作家庭冲突 工作满意度 离职意愿 澳门女性博彩庄荷
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