To develop the initial sandplay picture system for Chinese young internet addicts (ISPSCYIA) for the diagnosis and testing studies on internet addiction, 22 pictures were selected from the used pictures of initial san...To develop the initial sandplay picture system for Chinese young internet addicts (ISPSCYIA) for the diagnosis and testing studies on internet addiction, 22 pictures were selected from the used pictures of initial sandplay in existing research results of initial sandplay of Chinese young Internet addicts. 54 normal adolescents were recruited to evaluate the valence of the pictures on a nine-point scale in terms of clarity, pleasure and arousal. Results were shown that there were no significant differences between addiction pictures and non-addiction pictures in clarity, while there were significant differences in pleasure and arousal, as the scores of non-addiction pictures were higher. Correlation analysis indicated that there was obvious positive correlation among clarity, pleasure and arousal of addiction pictures & non-addiction pictures. The coefficients of internal consistency reliability and split-half reliability of 22 pictures’ scores exhibited both over 0.90. ISPSCYIA has proved typical and distinctive through valence assessment, which could be preliminarily applied to measure the characteristics of Chinese adolescents’ internet addiction.展开更多
Background and Aims:Growing evidence suggests that metabolic-related genes have a significant impact on the occurrence and development of hepatocellular carcinoma(HCC).However,the prognostic value of metabolic-related...Background and Aims:Growing evidence suggests that metabolic-related genes have a significant impact on the occurrence and development of hepatocellular carcinoma(HCC).However,the prognostic value of metabolic-related genes for HCC has not been fully revealed.Methods:mRNA sequencing and clinical data were obtained from The Cancer Genome Atlas and the GTEx Genotype-Tissue Expression comprehensive database.Differentially expressed metabolic-related genes in tumor tissues(n=374)and normal tissues(n=160)were identified by the Wilcoxon test.Time-dependent receiver operating characteristic curve analysis,univariate multivariate Cox regression analysis and Kaplan-Meier survival analysis were used to evaluate the predictive effectiveness and independence of the prognostic model.Two independent cohorts(International Cancer Genome Consortiums and GSE14520)were applied to verify the prognostic model.Results:Our study included a total of 793 patients with HCC.We constructed a risk score consisting of five metabolic-genes(BDH1,RRM2,CYP2C9,PLA2G7,and TXNRD1).For the overall survival rate,the low-risk group had a considerably higher rate than the high-risk group.Univariate and multivariate Cox regression analyses indicated that the risk score was an independent predictor for the prognosis of HCC.Conclusions:We constructed and validated a novel prognostic model,which may provide support for the precise treatment of HCC.展开更多
文摘To develop the initial sandplay picture system for Chinese young internet addicts (ISPSCYIA) for the diagnosis and testing studies on internet addiction, 22 pictures were selected from the used pictures of initial sandplay in existing research results of initial sandplay of Chinese young Internet addicts. 54 normal adolescents were recruited to evaluate the valence of the pictures on a nine-point scale in terms of clarity, pleasure and arousal. Results were shown that there were no significant differences between addiction pictures and non-addiction pictures in clarity, while there were significant differences in pleasure and arousal, as the scores of non-addiction pictures were higher. Correlation analysis indicated that there was obvious positive correlation among clarity, pleasure and arousal of addiction pictures & non-addiction pictures. The coefficients of internal consistency reliability and split-half reliability of 22 pictures’ scores exhibited both over 0.90. ISPSCYIA has proved typical and distinctive through valence assessment, which could be preliminarily applied to measure the characteristics of Chinese adolescents’ internet addiction.
文摘Background and Aims:Growing evidence suggests that metabolic-related genes have a significant impact on the occurrence and development of hepatocellular carcinoma(HCC).However,the prognostic value of metabolic-related genes for HCC has not been fully revealed.Methods:mRNA sequencing and clinical data were obtained from The Cancer Genome Atlas and the GTEx Genotype-Tissue Expression comprehensive database.Differentially expressed metabolic-related genes in tumor tissues(n=374)and normal tissues(n=160)were identified by the Wilcoxon test.Time-dependent receiver operating characteristic curve analysis,univariate multivariate Cox regression analysis and Kaplan-Meier survival analysis were used to evaluate the predictive effectiveness and independence of the prognostic model.Two independent cohorts(International Cancer Genome Consortiums and GSE14520)were applied to verify the prognostic model.Results:Our study included a total of 793 patients with HCC.We constructed a risk score consisting of five metabolic-genes(BDH1,RRM2,CYP2C9,PLA2G7,and TXNRD1).For the overall survival rate,the low-risk group had a considerably higher rate than the high-risk group.Univariate and multivariate Cox regression analyses indicated that the risk score was an independent predictor for the prognosis of HCC.Conclusions:We constructed and validated a novel prognostic model,which may provide support for the precise treatment of HCC.
