Purpose. To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion. Methods. The prospective comparative nonrandomized clinical interventional study included 28 p...Purpose. To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion. Methods. The prospective comparative nonrandomized clinical interventional study included 28 patients (28 eyes) with branch retinal vein occlusion. The study group consisting of 10 consecutive patients received an intravitreal injection of 20- 25mg of triamcinolone acetonide. The control group including 18 patients did not receive an intravitreal injection. The mean follow-up was 8.7± 4.4 months. Results. In the study group, mean visual acuity increased significantly (P=0.02) from 0.27± 0.11 preoperatively to a best postoperative visual acuity of 0.45± 0.27. Visual acuity measurements determined 1 month after the injection were significantly (P=0.027) higher than baseline values. Nine (90% ) eyes gained in visual acuity, with six (60% ) eyes showing an increase in visual acuity of at least two Snellen lines. In the ischaemic subgroup, visual acuity did not change significantly (0.18± 0.18 to 0.13± 0.04; P=0.66), while, in the nonischaemic subgroup, visual acuity increased significantly (P=0.012) from the baseline value to the best postoperative measurement (0.29± 0.09 to 0.53± 0.24). In the control group, baseline visual acuity and best visual acuity during the follow-up did not vary significantly (P=0.27). Comparing the study and control groups with each other, the gain in visual acuity was significantly higher in the study group at 1 month (P=0.016) and 2 months (P=0.012) after baseline. Conclusions. Intravitreal injection of triamcinolone acetonide can increase visual acuity in patients with branch retinal vein occlusion.展开更多
Purpose To compare optical coherence tomography (OCT) and confocal scanning la ser tomography (cSLT) for quantitative retinal thickness mapping of the macula a nd their ability to detect macular edema. Design Prospect...Purpose To compare optical coherence tomography (OCT) and confocal scanning la ser tomography (cSLT) for quantitative retinal thickness mapping of the macula a nd their ability to detect macular edema. Design Prospective, comparative, clini cal observational study. Methods The study population of 138 eyes (97 patients) was divided into a study group consisting of 45 (32.6%) eyes with macular edema and a control group consisting of 93 (67.4%) eyes without macular edema. All p atients underwent OCT and cSLT of the macula. Retinal thickness measurements obt ained by OCT were compared with signal width and edema index, determined by cSLT . Results The OCT measurements and cSLT edema index were significantly (P< 0 .00 1) correlated with each other. Correlation coefficients decreased (P< 0.001)with increasing diameter of the measurement circle. In the macular edema group, corr elation coefficients were significantly (P< 0.001) higher than in the control gr oup. To separate the study and control groups, receiver operator characteristic curves covered a larger area for OCT measurements than for cSLT measurements. Re tinal thickness measurements and edema index correlate with visual acuity (corre lation coefficient r=-0.653 for OCT, r=-0.608 for cSLT; P < .001). Conclusions Macular edema can be quantitatively mapped by OCT and cSLT. The retinal thickne ss and edema index measurements correlate with visual acuity. The fast and stand ard examination modes of OCT give similar measurements. Both OCT and cSLT can di fferentiate between eyes with and without macular edema, with OCT showing a high er predictive value.展开更多
文摘Purpose. To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion. Methods. The prospective comparative nonrandomized clinical interventional study included 28 patients (28 eyes) with branch retinal vein occlusion. The study group consisting of 10 consecutive patients received an intravitreal injection of 20- 25mg of triamcinolone acetonide. The control group including 18 patients did not receive an intravitreal injection. The mean follow-up was 8.7± 4.4 months. Results. In the study group, mean visual acuity increased significantly (P=0.02) from 0.27± 0.11 preoperatively to a best postoperative visual acuity of 0.45± 0.27. Visual acuity measurements determined 1 month after the injection were significantly (P=0.027) higher than baseline values. Nine (90% ) eyes gained in visual acuity, with six (60% ) eyes showing an increase in visual acuity of at least two Snellen lines. In the ischaemic subgroup, visual acuity did not change significantly (0.18± 0.18 to 0.13± 0.04; P=0.66), while, in the nonischaemic subgroup, visual acuity increased significantly (P=0.012) from the baseline value to the best postoperative measurement (0.29± 0.09 to 0.53± 0.24). In the control group, baseline visual acuity and best visual acuity during the follow-up did not vary significantly (P=0.27). Comparing the study and control groups with each other, the gain in visual acuity was significantly higher in the study group at 1 month (P=0.016) and 2 months (P=0.012) after baseline. Conclusions. Intravitreal injection of triamcinolone acetonide can increase visual acuity in patients with branch retinal vein occlusion.
文摘Purpose To compare optical coherence tomography (OCT) and confocal scanning la ser tomography (cSLT) for quantitative retinal thickness mapping of the macula a nd their ability to detect macular edema. Design Prospective, comparative, clini cal observational study. Methods The study population of 138 eyes (97 patients) was divided into a study group consisting of 45 (32.6%) eyes with macular edema and a control group consisting of 93 (67.4%) eyes without macular edema. All p atients underwent OCT and cSLT of the macula. Retinal thickness measurements obt ained by OCT were compared with signal width and edema index, determined by cSLT . Results The OCT measurements and cSLT edema index were significantly (P< 0 .00 1) correlated with each other. Correlation coefficients decreased (P< 0.001)with increasing diameter of the measurement circle. In the macular edema group, corr elation coefficients were significantly (P< 0.001) higher than in the control gr oup. To separate the study and control groups, receiver operator characteristic curves covered a larger area for OCT measurements than for cSLT measurements. Re tinal thickness measurements and edema index correlate with visual acuity (corre lation coefficient r=-0.653 for OCT, r=-0.608 for cSLT; P < .001). Conclusions Macular edema can be quantitatively mapped by OCT and cSLT. The retinal thickne ss and edema index measurements correlate with visual acuity. The fast and stand ard examination modes of OCT give similar measurements. Both OCT and cSLT can di fferentiate between eyes with and without macular edema, with OCT showing a high er predictive value.
