目的系统评价非药物干预(non-pharmaceutical intervention,NPI)对轻度认知障碍(mild cognitive impairment,MCI)患者抑郁的疗效和可接受性。方法检索PubMed、Embase、Web of Science、CINAHL、Cochrane Library、中国知网、万方数据、...目的系统评价非药物干预(non-pharmaceutical intervention,NPI)对轻度认知障碍(mild cognitive impairment,MCI)患者抑郁的疗效和可接受性。方法检索PubMed、Embase、Web of Science、CINAHL、Cochrane Library、中国知网、万方数据、维普和CBM数据库自建库至2024年1月6日发表的NPI治疗MCI患者抑郁的随机对照试验,采用Stata14.0进行网状Meta分析。结果共纳入55篇文献,涉及10种NPI。根据优选概率排名曲线下面积(surface under the cumulative ranking curve,SUCRA),疗效排名前3位的依次为认知行为疗法(cognitive behavioral therapy,CBT)、中国传统运动(Chinese traditional sport,CTS)和艺术疗法;可接受性排名前3位的依次为CBT、CTS和健康教育。结论CBT和CTS可能是改善MCI患者抑郁有效且易接受的NPI,可根据患者情况制定个性化的干预以达到最佳效果。展开更多
Platinum-based alloy nanoparticles are the most attractive catalysts for the oxygen reduction reaction at present,but an in-depth understanding of the relationship between their short-range structural information and ...Platinum-based alloy nanoparticles are the most attractive catalysts for the oxygen reduction reaction at present,but an in-depth understanding of the relationship between their short-range structural information and catalytic performance is still lacking.Herein,we present a synthetic strategy that uses transition-metal oxide-assisted thermal diffusion.PtCo/C catalysts with localized tetragonal distortion were obtained by controlling the thermal diffusion process of transition-metal elements.This localized structural distortion induced a significant strain effect on the nanoparticle surface,which further shortened the length of the Pt-Pt bond,improved the electronic state of the Pt surface,and enhanced the performance of the catalyst.PtCo/C catalysts with special short-range structures achieved excellent mass activity(2.27 Amg_(Pt)^(-1))and specific activity(3.34 A cm^(-2)).In addition,the localized tetragonal distortion-induced surface compression of the Pt skin improved the stability of the catalyst.The mass activity decreased by only 13% after 30,000 cycles.Enhanced catalyst activity and excellent durability have also been demonstrated in the proton exchange membrane fuel cell configuration.This study provides valuable insights into the development of advanced Pt-based nanocatalysts and paves the way for reducing noble-metal loading and increasing the catalytic activity and catalyst stability.展开更多
文摘目的系统评价非药物干预(non-pharmaceutical intervention,NPI)对轻度认知障碍(mild cognitive impairment,MCI)患者抑郁的疗效和可接受性。方法检索PubMed、Embase、Web of Science、CINAHL、Cochrane Library、中国知网、万方数据、维普和CBM数据库自建库至2024年1月6日发表的NPI治疗MCI患者抑郁的随机对照试验,采用Stata14.0进行网状Meta分析。结果共纳入55篇文献,涉及10种NPI。根据优选概率排名曲线下面积(surface under the cumulative ranking curve,SUCRA),疗效排名前3位的依次为认知行为疗法(cognitive behavioral therapy,CBT)、中国传统运动(Chinese traditional sport,CTS)和艺术疗法;可接受性排名前3位的依次为CBT、CTS和健康教育。结论CBT和CTS可能是改善MCI患者抑郁有效且易接受的NPI,可根据患者情况制定个性化的干预以达到最佳效果。
基金supported by the National Natural Science Foundation of China (Grant No.22278123).
文摘Platinum-based alloy nanoparticles are the most attractive catalysts for the oxygen reduction reaction at present,but an in-depth understanding of the relationship between their short-range structural information and catalytic performance is still lacking.Herein,we present a synthetic strategy that uses transition-metal oxide-assisted thermal diffusion.PtCo/C catalysts with localized tetragonal distortion were obtained by controlling the thermal diffusion process of transition-metal elements.This localized structural distortion induced a significant strain effect on the nanoparticle surface,which further shortened the length of the Pt-Pt bond,improved the electronic state of the Pt surface,and enhanced the performance of the catalyst.PtCo/C catalysts with special short-range structures achieved excellent mass activity(2.27 Amg_(Pt)^(-1))and specific activity(3.34 A cm^(-2)).In addition,the localized tetragonal distortion-induced surface compression of the Pt skin improved the stability of the catalyst.The mass activity decreased by only 13% after 30,000 cycles.Enhanced catalyst activity and excellent durability have also been demonstrated in the proton exchange membrane fuel cell configuration.This study provides valuable insights into the development of advanced Pt-based nanocatalysts and paves the way for reducing noble-metal loading and increasing the catalytic activity and catalyst stability.
