Traditional blockchain key management schemes store private keys in the same location,which can easily lead to security issues such as a single point of failure.Therefore,decentralized threshold key management schemes...Traditional blockchain key management schemes store private keys in the same location,which can easily lead to security issues such as a single point of failure.Therefore,decentralized threshold key management schemes have become a research focus for blockchain private key protection.The security of private keys for blockchain user wallet is highly related to user identity authentication and digital asset security.The threshold blockchain private key management schemes based on verifiable secret sharing have made some progress,but these schemes do not consider participants’self-interested behavior,and require trusted nodes to keep private key fragments,resulting in a narrow application scope and low deployment efficiency,which cannot meet the needs of personal wallet private key escrow and recovery in public blockchains.We design a private key management scheme based on rational secret sharing that considers the self-interest of participants in secret sharing protocols,and constrains the behavior of rational participants through reasonable mechanism design,making it more suitable in distributed scenarios such as the public blockchain.The proposed scheme achieves the escrow and recovery of personal wallet private keys without the participation of trusted nodes,and simulate its implementation on smart contracts.Compared to other existing threshold wallet solutions and keymanagement schemes based on password-protected secret sharing(PPSS),the proposed scheme has a wide range of applications,verifiable private key recovery,low communication overhead,higher computational efficiency when users perform one-time multi-key escrow,no need for trusted nodes,and personal rational constraints and anti-collusion attack capabilities.展开更多
[Objectives]This paper aimed to investigate the effect of Tuina combined with sling exercise therapy(SET)and psoas&abdominal training on serum 5-hydroxytryptamine(5-HT)andβ-endorphin(β-EP)levels in patients with...[Objectives]This paper aimed to investigate the effect of Tuina combined with sling exercise therapy(SET)and psoas&abdominal training on serum 5-hydroxytryptamine(5-HT)andβ-endorphin(β-EP)levels in patients with nonspecific low back pain(NLBP).[Methods]Total 46 patients with NLBP who visited the Tuina Department of the First Affiliated Hospital of Hainan Medical University from August 2019 to May 2020 were randomly and evenly divided into control group and treatment group.On the basis of Tuina therapy,the patients in the control group and treatment group were treated with psoas&abdominal training and SET,respectively.After the treatment,the serum 5-HT andβ-EP levels of the patients were detected.[Results]The serum 5-HT andβ-EP levels in the treatment group were significantly improved compared with the control group(P<0.05).[Conclusions]The nerve&muscle reconstruction techniques of Tuina combined with SET or psoas&abdominal training can improve serum 5-HT andβ-EP levels in patients with NLBP.展开更多
[Objectives]The purpose of this paper was to study the effects of Suoquan Yishen formula on mice with diabetic nephropathy(DN).[Methods]The mice were randomly divided into normal group,model group,irbesartan group,and...[Objectives]The purpose of this paper was to study the effects of Suoquan Yishen formula on mice with diabetic nephropathy(DN).[Methods]The mice were randomly divided into normal group,model group,irbesartan group,and high and low-dose Suoquan Yishen formula groups.The blood glucose level,BUN,Scr excretion and GSH activity and CAT activity were detected.[Results]The blood glucose levels of mice in the irbesartan group and high and low-dose Suoquan Yishen formula groups decreased.The BUN,PRO and Scr levels were higher and the GSH and CAT activity was lower in the model group compared with the normal group.After administration of Suoquan Yishen formula,the BUN,PRO and Scr levels of the DN mice decreased significantly,and the GSH and CAT activity increased significantly.[Conclusions]Suoquan Yishen formula can reduce blood glucose level,reduce PRO,BUN and Scr levels,and increase CAT and GSH activity in DN mice,thus protecting the ND mice.展开更多
Objective:To analyze the level changes of the degree of back pain by visual analogue scale(VAS),lumbar function(Japanese Orthopaedic Association Scores,JOA),muscle temperature,serum serotonin 5-hydroxytryptamine(5-HT)...Objective:To analyze the level changes of the degree of back pain by visual analogue scale(VAS),lumbar function(Japanese Orthopaedic Association Scores,JOA),muscle temperature,serum serotonin 5-hydroxytryptamine(5-HT)andβ-endorphin(β-EP)in patients of low back pain(LBP).Methods:64 LBP patients treated in the tuina department of first affiliated hospital of Hainan Medical University were randomly divided into observation group(32 cases)and control group(32 cases).The control group was treated with traditional filiform acupuncture needling,the observation group was treated with Chinese tuina.VAS,JOA,muscle temperature,5-HT,β-EP,these indexes were tested before and after treatment.Results:The VAS and JOA score in the observation group were significantly lower than those in the control group(P<0.01),the muscle temperature in the observation group and the control group increased significantly(P<0.01),and the observation group was higher than that in the control group(P<0.05);5-HT、β-EP was significant difference before and after treatment(P<0.01),and the level in observation group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Chinese tuina has significant clinical efficacy in the treatment of LBP.The medical infrared thermal imaging technology and serum pain detection technology is conducive to objectively helpful to analyze the exact efficacy of tuina in the treatment of LBP and its impact on relevant indexes.展开更多
COVID-19 has been discovered since December 2019 and has become a global pandemic recently,killing hundreds of thousands of people in 216 countries and regions around the world.COVID-19 has caused more than 4000 death...COVID-19 has been discovered since December 2019 and has become a global pandemic recently,killing hundreds of thousands of people in 216 countries and regions around the world.COVID-19 has caused more than 4000 deaths in China,seriously affecting national health and national economy.Since the outbreak of COVID-19,National Health Commission of the People's Republic of China has used the method of sino-western medicine to prevent and control COVID-19,effectively curbed the spread of the epidemic.But the TCM methods in the scheme are all oral prescriptions,less involving non-drug methods.Therefore,I searched the COVID-19 control methods published in various parts of the country,this paper plans to discuss how to improve immunity from the perspective of non-drug methods such as moxibustion,diet therapy,self massage,physical exercise skills and traditional music,hoping can helps the susceptible populations,infected,discharged and medical staff in COVID-19 epidemic.展开更多
Traditional practical teaching has problems on low reusability, high cost and low collaboration ability. To solve these problems, this paper proposes a solution that is to build and use a novel practical teaching plat...Traditional practical teaching has problems on low reusability, high cost and low collaboration ability. To solve these problems, this paper proposes a solution that is to build and use a novel practical teaching platform based on cloud computing. By utilizing advanced information technology, for example, cloud computing, this solution can present a unified service system providing practical teaching resource management, innovation resource management and knowledge management both inside and outside class. Moreover, an instance implementing the cloud-based practical teaching unified services system, Yun Hai, would be detailedly discussed in this paper. The system deployment, resource configuration and matched practice teaching mode will be presented. Yun Hai is independently developed by State Key Laboratory of Networking and Switching Technology and has been deployed and employed in many institutions. To verify the effectiveness of this teaching platform, we take Data Mining, a representative course of computer science, as an example, and analyze how the system would perform when applied to such course which contains cross-disciplinary knowledges. The practice indicates that this teaching system and practical teaching mode can improve convenience and flexibility on practical teaching resource. This kind of one-stop service can contribute to the overall teaching quality improvement.展开更多
COVID-19 belongs to the plague category of Traditional Chinese Medicine.It has been confirmed in many ancient books and modern clinical studies that the acupuncture and moxibustion can cure the plague.In this episode ...COVID-19 belongs to the plague category of Traditional Chinese Medicine.It has been confirmed in many ancient books and modern clinical studies that the acupuncture and moxibustion can cure the plague.In this episode of COVID-19,National Health Commission of the People's Republic of China and National Administration of Traditional Chinese Medicine Jointly issued the Diagnosis and Treatment of Corona Virus Disease-19(7th edition).It mentions the treatment program of acupuncture and moxibustion participating in the prevention and treatment of COVID-19.Liu Baoyan's team analyzed the ideas of acupuncture and moxibustion treatment for COVID-19.However,the clinical advantages of acupuncture and moxibustion still need to be further clarified.In the treatment of many clinical symptoms of COVID-19,acupuncture therapy has a good clinical effect,so the purpose of our discussion on the advantages is to improve the clinical accuracy and efficacy.展开更多
[Objectives]To analyze the clinical effect of Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine on chronic colitis.[Methods]120 patients with chronic enteritis admitted to Qionghai Hospital of Traditional Chin...[Objectives]To analyze the clinical effect of Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine on chronic colitis.[Methods]120 patients with chronic enteritis admitted to Qionghai Hospital of Traditional Chinese Medicine from October 2020 to March 2022 were selected as the research objects,and were randomly divided into combined group(62 cases)and conventional group(58 cases).Patients in the conventional group were treated with oral mesalazine on the basis of conventional treatment,while patients in the combined group were treated with Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine.The clinical efficacy,inflammatory factor level,colonic mucosal lesion degree,quality of life and TCM syndrome scores of the two groups were compared.[Results]The total clinical effective rate in the combined group was higher than that in the conventional group(P<0.05).After treatment,the levels of inflammatory factors in the two groups were lower than those before treatment,and the levels of interleukin-6(IL-6),C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)in the combined group were lower than those in the conventional group(P<0.001).After treatment,the Baron and Geboes scores of the two groups were lower than those before treatment,and the Baron and Geboes scores of the combined group were lower than those of the conventional group(P<0.001).After treatment,the scores of quality of life in the two groups were higher than those before treatment,while the scores of TCM syndromes were lower than those before treatment.The scores of quality of life in the combined group were higher than those in the conventional group(P<0.001).[Conclusions]Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine can obviously improve the curative effect,reduce the level of inflammatory factors,improve the degree of colonic mucosal lesions and improve the quality of life of patients with chronic colitis,which is worthy of popularization and application in clinical practice.展开更多
Real-time Fraud Detection has always been a challenging task, especially in financial, insurance, and telecom industries. There are mainly three methods, which are rule set, outlier detection and classification to sol...Real-time Fraud Detection has always been a challenging task, especially in financial, insurance, and telecom industries. There are mainly three methods, which are rule set, outlier detection and classification to solve the problem. But those methods have some drawbacks respectively. To overcome these limitations, we propose a new algorithm UAF (Usage Amount Forecast).Firstly, Manhattan distance is used to measure the similarity between fraudulent instances and normal ones. Secondly, UAF gives real-time score which detects the fraud early and reduces as much economic loss as possible. Experiments on various real-world datasets demonstrate the high potential of UAF for processing real-time data and predicting fraudulent users.展开更多
Many recently proposed subspace clustering methods suffer from two severe problems.First,the algorithms typically scale exponentially with the data dimensionality or the subspace dimensionality of clusters.Second,the ...Many recently proposed subspace clustering methods suffer from two severe problems.First,the algorithms typically scale exponentially with the data dimensionality or the subspace dimensionality of clusters.Second,the clustering results are often sensitive to input parameters.In this paper,a fast algorithm of subspace clustering using attribute clustering is proposed to overcome these limitations.This algorithm first filters out redundant attributes by computing the Gini coef-ficient.To evaluate the correlation of every two non-redundant attributes,the relation matrix of non-redund-ant attributes is constructed based on the relation function of two dimensional united Gini coefficients.After applying an overlapping clustering algorithm on the relation matrix,the candidate of all interesting subspaces is achieved.Finally,all subspace clusters can be derived by clustering on interesting subspaces.Experiments on both synthesis and real datasets show that the new algorithm not only achieves a significant gain of runtime and quality to find subspace clusters,but also is insensitive to input parameters.展开更多
基金the State’s Key Project of Research and Development Plan under Grant 2022YFB2701400in part by the National Natural Science Foundation of China under Grants 62272124 and 62361010+4 种基金in part by the Science and Technology Planning Project of Guizhou Province under Grant[2020]5017in part by the Research Project of Guizhou University for Talent Introduction underGrant[2020]61in part by theCultivation Project of Guizhou University under Grant[2019]56in part by the Open Fund of Key Laboratory of Advanced Manufacturing Technology,Ministry of Education under Grant GZUAMT2021KF[01]the Science and Technology Program of Guizhou Province(No.[2023]371).
文摘Traditional blockchain key management schemes store private keys in the same location,which can easily lead to security issues such as a single point of failure.Therefore,decentralized threshold key management schemes have become a research focus for blockchain private key protection.The security of private keys for blockchain user wallet is highly related to user identity authentication and digital asset security.The threshold blockchain private key management schemes based on verifiable secret sharing have made some progress,but these schemes do not consider participants’self-interested behavior,and require trusted nodes to keep private key fragments,resulting in a narrow application scope and low deployment efficiency,which cannot meet the needs of personal wallet private key escrow and recovery in public blockchains.We design a private key management scheme based on rational secret sharing that considers the self-interest of participants in secret sharing protocols,and constrains the behavior of rational participants through reasonable mechanism design,making it more suitable in distributed scenarios such as the public blockchain.The proposed scheme achieves the escrow and recovery of personal wallet private keys without the participation of trusted nodes,and simulate its implementation on smart contracts.Compared to other existing threshold wallet solutions and keymanagement schemes based on password-protected secret sharing(PPSS),the proposed scheme has a wide range of applications,verifiable private key recovery,low communication overhead,higher computational efficiency when users perform one-time multi-key escrow,no need for trusted nodes,and personal rational constraints and anti-collusion attack capabilities.
基金Natural Science Foundation of Hainan Province(No.818QN248,No.818MS061)。
文摘[Objectives]This paper aimed to investigate the effect of Tuina combined with sling exercise therapy(SET)and psoas&abdominal training on serum 5-hydroxytryptamine(5-HT)andβ-endorphin(β-EP)levels in patients with nonspecific low back pain(NLBP).[Methods]Total 46 patients with NLBP who visited the Tuina Department of the First Affiliated Hospital of Hainan Medical University from August 2019 to May 2020 were randomly and evenly divided into control group and treatment group.On the basis of Tuina therapy,the patients in the control group and treatment group were treated with psoas&abdominal training and SET,respectively.After the treatment,the serum 5-HT andβ-EP levels of the patients were detected.[Results]The serum 5-HT andβ-EP levels in the treatment group were significantly improved compared with the control group(P<0.05).[Conclusions]The nerve&muscle reconstruction techniques of Tuina combined with SET or psoas&abdominal training can improve serum 5-HT andβ-EP levels in patients with NLBP.
基金Supported by Natural Science Foundation of Hainan Province(2019CXTD407)National Natural Science Foundation of China(81860836).
文摘[Objectives]The purpose of this paper was to study the effects of Suoquan Yishen formula on mice with diabetic nephropathy(DN).[Methods]The mice were randomly divided into normal group,model group,irbesartan group,and high and low-dose Suoquan Yishen formula groups.The blood glucose level,BUN,Scr excretion and GSH activity and CAT activity were detected.[Results]The blood glucose levels of mice in the irbesartan group and high and low-dose Suoquan Yishen formula groups decreased.The BUN,PRO and Scr levels were higher and the GSH and CAT activity was lower in the model group compared with the normal group.After administration of Suoquan Yishen formula,the BUN,PRO and Scr levels of the DN mice decreased significantly,and the GSH and CAT activity increased significantly.[Conclusions]Suoquan Yishen formula can reduce blood glucose level,reduce PRO,BUN and Scr levels,and increase CAT and GSH activity in DN mice,thus protecting the ND mice.
文摘Objective:To analyze the level changes of the degree of back pain by visual analogue scale(VAS),lumbar function(Japanese Orthopaedic Association Scores,JOA),muscle temperature,serum serotonin 5-hydroxytryptamine(5-HT)andβ-endorphin(β-EP)in patients of low back pain(LBP).Methods:64 LBP patients treated in the tuina department of first affiliated hospital of Hainan Medical University were randomly divided into observation group(32 cases)and control group(32 cases).The control group was treated with traditional filiform acupuncture needling,the observation group was treated with Chinese tuina.VAS,JOA,muscle temperature,5-HT,β-EP,these indexes were tested before and after treatment.Results:The VAS and JOA score in the observation group were significantly lower than those in the control group(P<0.01),the muscle temperature in the observation group and the control group increased significantly(P<0.01),and the observation group was higher than that in the control group(P<0.05);5-HT、β-EP was significant difference before and after treatment(P<0.01),and the level in observation group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Chinese tuina has significant clinical efficacy in the treatment of LBP.The medical infrared thermal imaging technology and serum pain detection technology is conducive to objectively helpful to analyze the exact efficacy of tuina in the treatment of LBP and its impact on relevant indexes.
基金Special Project for the Tackling COVID-19(No.XGZX2020006)
文摘COVID-19 has been discovered since December 2019 and has become a global pandemic recently,killing hundreds of thousands of people in 216 countries and regions around the world.COVID-19 has caused more than 4000 deaths in China,seriously affecting national health and national economy.Since the outbreak of COVID-19,National Health Commission of the People's Republic of China has used the method of sino-western medicine to prevent and control COVID-19,effectively curbed the spread of the epidemic.But the TCM methods in the scheme are all oral prescriptions,less involving non-drug methods.Therefore,I searched the COVID-19 control methods published in various parts of the country,this paper plans to discuss how to improve immunity from the perspective of non-drug methods such as moxibustion,diet therapy,self massage,physical exercise skills and traditional music,hoping can helps the susceptible populations,infected,discharged and medical staff in COVID-19 epidemic.
基金supported by the Projects on International Scientific and Technological Cooperation under the National Key R&D Program(NKP)(No.2016YFE0204500)the National Natural Science Foundation of China under Grants(No.61671081,No.61720106007)+1 种基金the Beijing Natural Science Foundation under Grant(No.4172042)the Fundamental Research Funds for the Central Universities,Beijing University of Posts and Telecommunications 2017 Education and Teaching Reform Project (No.2017JY31)
文摘Traditional practical teaching has problems on low reusability, high cost and low collaboration ability. To solve these problems, this paper proposes a solution that is to build and use a novel practical teaching platform based on cloud computing. By utilizing advanced information technology, for example, cloud computing, this solution can present a unified service system providing practical teaching resource management, innovation resource management and knowledge management both inside and outside class. Moreover, an instance implementing the cloud-based practical teaching unified services system, Yun Hai, would be detailedly discussed in this paper. The system deployment, resource configuration and matched practice teaching mode will be presented. Yun Hai is independently developed by State Key Laboratory of Networking and Switching Technology and has been deployed and employed in many institutions. To verify the effectiveness of this teaching platform, we take Data Mining, a representative course of computer science, as an example, and analyze how the system would perform when applied to such course which contains cross-disciplinary knowledges. The practice indicates that this teaching system and practical teaching mode can improve convenience and flexibility on practical teaching resource. This kind of one-stop service can contribute to the overall teaching quality improvement.
基金Special project for the tackling COVID-19(No.XGZX2020006)College Students'Innovative Entrepreneurial Training Plan Program(No.X202011810063)
文摘COVID-19 belongs to the plague category of Traditional Chinese Medicine.It has been confirmed in many ancient books and modern clinical studies that the acupuncture and moxibustion can cure the plague.In this episode of COVID-19,National Health Commission of the People's Republic of China and National Administration of Traditional Chinese Medicine Jointly issued the Diagnosis and Treatment of Corona Virus Disease-19(7th edition).It mentions the treatment program of acupuncture and moxibustion participating in the prevention and treatment of COVID-19.Liu Baoyan's team analyzed the ideas of acupuncture and moxibustion treatment for COVID-19.However,the clinical advantages of acupuncture and moxibustion still need to be further clarified.In the treatment of many clinical symptoms of COVID-19,acupuncture therapy has a good clinical effect,so the purpose of our discussion on the advantages is to improve the clinical accuracy and efficacy.
基金Supported by National Natural Science Foundation of China (81760674)Foundation of Hainan Provincial Health Commission (21A200444)
文摘[Objectives]To analyze the clinical effect of Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine on chronic colitis.[Methods]120 patients with chronic enteritis admitted to Qionghai Hospital of Traditional Chinese Medicine from October 2020 to March 2022 were selected as the research objects,and were randomly divided into combined group(62 cases)and conventional group(58 cases).Patients in the conventional group were treated with oral mesalazine on the basis of conventional treatment,while patients in the combined group were treated with Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine.The clinical efficacy,inflammatory factor level,colonic mucosal lesion degree,quality of life and TCM syndrome scores of the two groups were compared.[Results]The total clinical effective rate in the combined group was higher than that in the conventional group(P<0.05).After treatment,the levels of inflammatory factors in the two groups were lower than those before treatment,and the levels of interleukin-6(IL-6),C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)in the combined group were lower than those in the conventional group(P<0.001).After treatment,the Baron and Geboes scores of the two groups were lower than those before treatment,and the Baron and Geboes scores of the combined group were lower than those of the conventional group(P<0.001).After treatment,the scores of quality of life in the two groups were higher than those before treatment,while the scores of TCM syndromes were lower than those before treatment.The scores of quality of life in the combined group were higher than those in the conventional group(P<0.001).[Conclusions]Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine can obviously improve the curative effect,reduce the level of inflammatory factors,improve the degree of colonic mucosal lesions and improve the quality of life of patients with chronic colitis,which is worthy of popularization and application in clinical practice.
基金This paper is supported by the National Natural Science Foundation of China (61272515), and National Science & Technology Pillar Program (2015BAH03F02).
文摘Real-time Fraud Detection has always been a challenging task, especially in financial, insurance, and telecom industries. There are mainly three methods, which are rule set, outlier detection and classification to solve the problem. But those methods have some drawbacks respectively. To overcome these limitations, we propose a new algorithm UAF (Usage Amount Forecast).Firstly, Manhattan distance is used to measure the similarity between fraudulent instances and normal ones. Secondly, UAF gives real-time score which detects the fraud early and reduces as much economic loss as possible. Experiments on various real-world datasets demonstrate the high potential of UAF for processing real-time data and predicting fraudulent users.
基金This work was supported by the National Basic Research Program of China(No.2007CB307100)the National Natural Science Foundation of China(Grant No.60432010).
文摘Many recently proposed subspace clustering methods suffer from two severe problems.First,the algorithms typically scale exponentially with the data dimensionality or the subspace dimensionality of clusters.Second,the clustering results are often sensitive to input parameters.In this paper,a fast algorithm of subspace clustering using attribute clustering is proposed to overcome these limitations.This algorithm first filters out redundant attributes by computing the Gini coef-ficient.To evaluate the correlation of every two non-redundant attributes,the relation matrix of non-redund-ant attributes is constructed based on the relation function of two dimensional united Gini coefficients.After applying an overlapping clustering algorithm on the relation matrix,the candidate of all interesting subspaces is achieved.Finally,all subspace clusters can be derived by clustering on interesting subspaces.Experiments on both synthesis and real datasets show that the new algorithm not only achieves a significant gain of runtime and quality to find subspace clusters,but also is insensitive to input parameters.