Dental implant is an effective method in the treatment of missing teeth.The process of osseointegration of implant teeth involves the coordinated operation of immune system and bone system.The interaction between cell...Dental implant is an effective method in the treatment of missing teeth.The process of osseointegration of implant teeth involves the coordinated operation of immune system and bone system.The interaction between cells is closely related to bone formation and repair.Exosomes are important intercellular communication molecules.They were originally found in the supernatant of sheep erythrocytes cultured in vitro.They are micro vesicles with a diameter of 40~150 nm.They exist in a variety of cells and body fluids.They enter the target cells by endocytosis and transport,affecting the expression of cell genes and changing the fate of cells.It has an important regulatory function in the microenvironment of implant bone binding.It plays a role in bone remodeling through small molecular RNA,specific proteins and other growth factors secreted by different cells.This article reviews the role of bone derived cellderived exosomes in bone remodeling and their function in implant osseointegration.展开更多
绿色金融标准是界定项目、资产和活动是否“绿色”、避免“洗绿”的关键技术依据,绿色金融标准体系是绿色金融发展的重要基础设施。本文以2015-2023年中国知网和Web of Science数据库主题为“绿色金融标准”的中英论文作为研究对象,进...绿色金融标准是界定项目、资产和活动是否“绿色”、避免“洗绿”的关键技术依据,绿色金融标准体系是绿色金融发展的重要基础设施。本文以2015-2023年中国知网和Web of Science数据库主题为“绿色金融标准”的中英论文作为研究对象,进行绩效分析和科学图谱分析,总结中外绿色金融标准化研究趋势,提出未来我国绿色金融标准化工作的重点方向。结果表明:中文论文绿色金融标准化的研究热点从“一带一路”、可持续发展等相关政策,绿色债券等绿色金融体系研究向环境信息披露、ESG、高质量发展转变,自2022年,研究前沿为“双碳”目标背景下的转型金融。英文论文的研究热点从绿色债券等绿色金融体系向公司社会责任、ESG转变,自2019年,研究前沿为欧盟可持续金融分类法。未来我国绿色金融标准化应进一步提升绿色金融标准体系的国内外一致性程度,推动我国话语体系与国际趋同;加快补齐绿色金融标准短板,出台转型金融统一指导标准;优化绿色金融标准体系的供给结构,建立国家颁布标准和市场自主制定标准共同构成的二元绿色金融标准体系。展开更多
Soil water deficit and salt stress are major limiting factors of plant growth and agricultural productivity. The primary root is the first organ to perceive the stress signals for drought and salt stress. In this stud...Soil water deficit and salt stress are major limiting factors of plant growth and agricultural productivity. The primary root is the first organ to perceive the stress signals for drought and salt stress. In this study, maize plant subjected to drought, salt and combined stresses displayed a significantly reduced primary root length relative to the control plants. GC-MS was used to determine changes in the metabolites of the primary root of maize in response to salt, drought and combined stresses. A total of 86 metabolites were measured, including 29 amino acids and amines, 21 organic acids, four fatty acids, six phosphoric acids, 10 sugars, 10 polyols, and six others. Among these, 53 metabolites with a significant change under different stresses were identified in the primary root, and the content of most metabolites showed down-accumulation. A total of four and 18 metabolites showed significant up-and down-accumulation to all three treatments, respectively. The levels of several compatible solutes, including sugars and polyols, were increased to help maintain the osmotic balance. The levels of metabolites involved in the TCA cycle, including citric acid, ketoglutaric acid, fumaric acid, and malic acid, were reduced in the primary root. The contents of metabolites in the shikimate pathway, such as quinic acid and shikimic acid, were significantly decreased. This study reveals the complex metabolic responses of the primary root to combined drought and salt stresses and extends our understanding of the mechanisms involved in root responses to abiotic tolerance in maize.展开更多
基金Scientific Research Project of Hainan Provincial Department of Education (No.Hnky2018ZD-7)。
文摘Dental implant is an effective method in the treatment of missing teeth.The process of osseointegration of implant teeth involves the coordinated operation of immune system and bone system.The interaction between cells is closely related to bone formation and repair.Exosomes are important intercellular communication molecules.They were originally found in the supernatant of sheep erythrocytes cultured in vitro.They are micro vesicles with a diameter of 40~150 nm.They exist in a variety of cells and body fluids.They enter the target cells by endocytosis and transport,affecting the expression of cell genes and changing the fate of cells.It has an important regulatory function in the microenvironment of implant bone binding.It plays a role in bone remodeling through small molecular RNA,specific proteins and other growth factors secreted by different cells.This article reviews the role of bone derived cellderived exosomes in bone remodeling and their function in implant osseointegration.
文摘绿色金融标准是界定项目、资产和活动是否“绿色”、避免“洗绿”的关键技术依据,绿色金融标准体系是绿色金融发展的重要基础设施。本文以2015-2023年中国知网和Web of Science数据库主题为“绿色金融标准”的中英论文作为研究对象,进行绩效分析和科学图谱分析,总结中外绿色金融标准化研究趋势,提出未来我国绿色金融标准化工作的重点方向。结果表明:中文论文绿色金融标准化的研究热点从“一带一路”、可持续发展等相关政策,绿色债券等绿色金融体系研究向环境信息披露、ESG、高质量发展转变,自2022年,研究前沿为“双碳”目标背景下的转型金融。英文论文的研究热点从绿色债券等绿色金融体系向公司社会责任、ESG转变,自2019年,研究前沿为欧盟可持续金融分类法。未来我国绿色金融标准化应进一步提升绿色金融标准体系的国内外一致性程度,推动我国话语体系与国际趋同;加快补齐绿色金融标准短板,出台转型金融统一指导标准;优化绿色金融标准体系的供给结构,建立国家颁布标准和市场自主制定标准共同构成的二元绿色金融标准体系。
基金supported by grants from the National Key Technology Research and Development Program of Ministry of Science and Technology of China (2016YFD0100303)the National Natural Science Foundation of China (31972487, 31902101 and 31801028)+2 种基金the Key Technology Research and Development Program of Jiangsu, China (BE2018325)the Natural Science Foundation of Jiangsu Province, China (BK20180920)the project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions, China (PAPD)。
文摘Soil water deficit and salt stress are major limiting factors of plant growth and agricultural productivity. The primary root is the first organ to perceive the stress signals for drought and salt stress. In this study, maize plant subjected to drought, salt and combined stresses displayed a significantly reduced primary root length relative to the control plants. GC-MS was used to determine changes in the metabolites of the primary root of maize in response to salt, drought and combined stresses. A total of 86 metabolites were measured, including 29 amino acids and amines, 21 organic acids, four fatty acids, six phosphoric acids, 10 sugars, 10 polyols, and six others. Among these, 53 metabolites with a significant change under different stresses were identified in the primary root, and the content of most metabolites showed down-accumulation. A total of four and 18 metabolites showed significant up-and down-accumulation to all three treatments, respectively. The levels of several compatible solutes, including sugars and polyols, were increased to help maintain the osmotic balance. The levels of metabolites involved in the TCA cycle, including citric acid, ketoglutaric acid, fumaric acid, and malic acid, were reduced in the primary root. The contents of metabolites in the shikimate pathway, such as quinic acid and shikimic acid, were significantly decreased. This study reveals the complex metabolic responses of the primary root to combined drought and salt stresses and extends our understanding of the mechanisms involved in root responses to abiotic tolerance in maize.
