Worldwide, the incidence of birth defects in low-income countries is 6.42%, while in middle-income and high-income countries it is 5.57% and 4.72%, respectively;approximately 303, 000 newborns die from birth defects e...Worldwide, the incidence of birth defects in low-income countries is 6.42%, while in middle-income and high-income countries it is 5.57% and 4.72%, respectively;approximately 303, 000 newborns die from birth defects each year. In China, the incidence of birth defects is about 5.6%, and around 8.14 million people have congenital disabilities, accounting for 9.6% of total disabled people[1]. Birth defect remains a major clinical and public health challenge because of its high fatality rate and protracted and severe sequela.展开更多
Left-behind children comprise a special population inChinese rural areas. According to the 2007 China Census,the number ofleft-behind children aged≤14 years was estimated at 58 million which suggested that these chil...Left-behind children comprise a special population inChinese rural areas. According to the 2007 China Census,the number ofleft-behind children aged≤14 years was estimated at 58 million which suggested that these childrencon stituted a展开更多
Objective To evaluate the predictive performance of anthropometric indices for metabolic syndrome(Met S)among Chinese adolescents with different nutritional status.Methods We recruited 9,513 adolescents aged 10–18 ye...Objective To evaluate the predictive performance of anthropometric indices for metabolic syndrome(Met S)among Chinese adolescents with different nutritional status.Methods We recruited 9,513 adolescents aged 10–18 years from seven provinces in China during September 2014.Anthropometric indices and blood pressure were measured at recruitment,and blood samples were collected for determining fasting plasma glucose and lipid profile.Receiver operating characteristic(ROC)analyses were used to assess the predictive performance of anthropometric indices,including body mass index(BMI)percentile,waist circumference percentile,waist-height ratio,and waist-hip ratio.Results Overall,the four anthropometric indices showed good accuracy for predicting Met S with areas under ROC curves(AUCs)ranging from 0.86 to 0.94;similar AUCs ranging from 0.73 to 0.99 were observed for participants with normal weight.The performance of all four indices was poor in overweight and obese participants,with AUCs ranging from 0.66 to 0.77 and from 0.60 to 0.67,respectively.Waist circumference showed relatively better performance in all the subgroup analyses.Conclusions We suggest using anthropometric indices with the cutoff values presented here for predicting Met S in the overall and normal-weight adolescent population,but not in the overweight and obese adolescent population where more specific screening tests are required.展开更多
基金supported by the National Natural Science Foundation of China [No.81172680]
文摘Worldwide, the incidence of birth defects in low-income countries is 6.42%, while in middle-income and high-income countries it is 5.57% and 4.72%, respectively;approximately 303, 000 newborns die from birth defects each year. In China, the incidence of birth defects is about 5.6%, and around 8.14 million people have congenital disabilities, accounting for 9.6% of total disabled people[1]. Birth defect remains a major clinical and public health challenge because of its high fatality rate and protracted and severe sequela.
基金supported by grants from the National Natural Science Foundation of China [81172680]
文摘Left-behind children comprise a special population inChinese rural areas. According to the 2007 China Census,the number ofleft-behind children aged≤14 years was estimated at 58 million which suggested that these childrencon stituted a
基金supported by the Medical Research Council,the Research Special Fund for Public Welfare of Health[Grant No.201202010]Hunan Provincial Natural Science Foundation of China[Grant No.2018JJ2553]。
文摘Objective To evaluate the predictive performance of anthropometric indices for metabolic syndrome(Met S)among Chinese adolescents with different nutritional status.Methods We recruited 9,513 adolescents aged 10–18 years from seven provinces in China during September 2014.Anthropometric indices and blood pressure were measured at recruitment,and blood samples were collected for determining fasting plasma glucose and lipid profile.Receiver operating characteristic(ROC)analyses were used to assess the predictive performance of anthropometric indices,including body mass index(BMI)percentile,waist circumference percentile,waist-height ratio,and waist-hip ratio.Results Overall,the four anthropometric indices showed good accuracy for predicting Met S with areas under ROC curves(AUCs)ranging from 0.86 to 0.94;similar AUCs ranging from 0.73 to 0.99 were observed for participants with normal weight.The performance of all four indices was poor in overweight and obese participants,with AUCs ranging from 0.66 to 0.77 and from 0.60 to 0.67,respectively.Waist circumference showed relatively better performance in all the subgroup analyses.Conclusions We suggest using anthropometric indices with the cutoff values presented here for predicting Met S in the overall and normal-weight adolescent population,but not in the overweight and obese adolescent population where more specific screening tests are required.
