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Tailored nutritional interventions: A precision approach to managing gestational diabetes mellitus
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作者 Babita Pande Henu Kumar Verma lvks bhaskar 《World Journal of Diabetes》 SCIE 2024年第5期1045-1047,共3页
Gestational diabetes mellitus(GDM)is a risk to maternal-fetal health due to uncertain diagnostic criteria and treatment options.Luo's study demonstrated the efficacy of customized nutritional therapies in controll... Gestational diabetes mellitus(GDM)is a risk to maternal-fetal health due to uncertain diagnostic criteria and treatment options.Luo's study demonstrated the efficacy of customized nutritional therapies in controlling GDM.Tailored strategies led to significant body weight loss,improved glucolipid metabolism,and fewer prenatal and newborn problems.This holistic approach,which emphasizes the notion of’chrononutrition’,takes into account optimal meal timing that is in sync with circadian rhythms,as well as enhanced sleep hygiene.Implementing tailored dietary therapy,managing meal timing,and ensuring appropriate sleep may improve results for women with GDM,opening up a possible avenue for multi-center trials. 展开更多
关键词 Gestational diabetes mellitus METABOLISM NUTRITION Maternal-fetal health Dietary therapy
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Emerging perspectives on RNA virus-mediated infections:from pathogenesis to therapeutic interventions
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作者 Pratik Mohanty Poojarani Panda +3 位作者 Rakesh Kumar Acharya Babita Pande lvks bhaskar Henu Kumar Verma 《World Journal of Virology》 2023年第5期242-255,共14页
RNA viruses continue to pose significant threats to global public health,necessitating a profound understanding of their pathogenic mechanisms and the development of effective therapeutic interventions.This manuscript... RNA viruses continue to pose significant threats to global public health,necessitating a profound understanding of their pathogenic mechanisms and the development of effective therapeutic interventions.This manuscript provides a comprehensive overview of emerging perspectives on RNA virus-mediated infections,spanning from the intricate intricacies of viral pathogenesis to the forefront of innovative therapeutic strategies.A critical exploration of antiviral drugs sets the stage,highlighting the diverse classes of compounds that target various stages of the viral life cycle,underscoring the ongoing efforts to combat viral infections.Central to this discussion is the exploration of RNA-based therapeutics,with a spotlight on messenger RNA(mRNA)-based approaches that have revolutionized the landscape of antiviral interventions.Furthermore,the manuscript delves into the intricate world of delivery systems,exploring innovative technologies designed to enhance the efficiency and safety of mRNA vaccines.By analyzing the challenges and advancements in delivery mechanisms,this review offers a roadmap for future research and development in this critical area.Beyond conventional infectious diseases,the document explores the expanding applications of mRNA vaccines,including their promising roles in cancer immunotherapy and personalized medicine approaches.This manuscript serves as a valuable resource for researchers,clinicians,and policymakers alike,offering a nuanced perspective on RNA virus pathogenesis and the cutting-edge therapeutic interventions.By synthesizing the latest advancements and challenges,this review contributes significantly to the ongoing discourse in the field,driving the development of novel strategies to combat RNA virus-mediated infections effectively. 展开更多
关键词 RNA virus INFECTIONS THERAPEUTICS Drug target PATHOGENESIS
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Gender differences in the relationship between alcohol consumption and gastric cancer risk are uncertain and not well-delineated 被引量:2
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作者 Henu Kumar Verma lvks bhaskar 《World Journal of Gastrointestinal Oncology》 SCIE 2021年第12期2216-2218,共3页
The role of alcoholic and other beverage consumption in the etiology of gastric cancer is unknown.Several studies have summarized and established a significant association between heavy alcohol consumption and gastric... The role of alcoholic and other beverage consumption in the etiology of gastric cancer is unknown.Several studies have summarized and established a significant association between heavy alcohol consumption and gastric cancer risk,but evidence on alcohol-related cancer risk is conflicting. 展开更多
关键词 ALCOHOL Gastric cancer Meta-analysis Gender and alcohol intake Alcohol consumption
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SARS-CoV-2 infection in people with pre-existing liver disease:Further research is warranted
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作者 Henu Kumar Verma lvks bhaskar 《World Journal of Gastroenterology》 SCIE CAS 2021年第45期7855-7858,共4页
Patients with severe liver disease who have been infected with severe acute respiratory syndrome coronavirus-2(coronavirus disease 2019)frequently develop acute respiratory distress syndrome and multiple organ failure... Patients with severe liver disease who have been infected with severe acute respiratory syndrome coronavirus-2(coronavirus disease 2019)frequently develop acute respiratory distress syndrome and multiple organ failure,with a high mortality rate,as a result of the hyper-proinflammatory state known as the cytokine storm.Clinicians must recognize cytokine storms earlier to avoid intensive care admission and multi-organ damage,a critical life-threatening condition with prognostic and therapeutic implications. 展开更多
关键词 Cytokine storm Liver disease Angiotensin-converting enzyme 2 THERAPEUTICS Inflammatory markers
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