Global mean sea level(GMSL) change is one of the important indicators of global climate change and is a crucial scientific issue of continuing interest. As satellite altimeter data, the Gravity Recovery and Climate Ex...Global mean sea level(GMSL) change is one of the important indicators of global climate change and is a crucial scientific issue of continuing interest. As satellite altimeter data, the Gravity Recovery and Climate Experiment(GRACE) and Argo continue to be updated, especially with the release of GRACE Follow-On(GRACE-FO) data, making it necessary to combine these latest data to estimate sea level change. Determinations on whether the GRACE and GRACE-FO observation systems provide unbiased global observation data have not been effectively evaluated. Therefore, this research mainly investigated the consistency of GRACE and GRACE-FO observation data in studying GMSL change. By comparing the sum of the GMSL calculated by the two gravity satellites and Argo data with the GMSL calculated by satellite altimeters, the discrepancy between GRACE-FO + Argo and satellite altimeter data is about 7.9 ± 2.3 mm, which is likely derived from the inconsistency between GRACE and GRACE-FO data.展开更多
The low cycle fatigue behavior of zirconium−titanium−steel composite plate under symmetrical and asymmetric stress control was studied.The effects of mean stress and stress amplitude on cyclic deformation,ratcheting e...The low cycle fatigue behavior of zirconium−titanium−steel composite plate under symmetrical and asymmetric stress control was studied.The effects of mean stress and stress amplitude on cyclic deformation,ratcheting effect and damage mechanism were discussed in detail.The results show that under symmetric stress control,the forward ratcheting deformation is observed.Under asymmetric stress control,the ratcheting strain increases rapidly with mean stress and stress amplitude increasing.Under high stress amplitude,the influence of mean stress is more significant.In addition,by studying the variation of strain energy density,it is found that the stress amplitude mainly promotes the fatigue damage,while the mean stress leads to the ratcheting damage.In addition,fractographic observation shows that the crack initiates in the brittle metal compound at the interface,and the steel has higher resistance to crack propagation.Finally,the accuracy of life prediction model considering ratcheting effect is discussed in detail,and a high-precision life prediction model directly based on mean stress and stress amplitude is proposed.展开更多
This paper is concerned with the leader-follower consensus problem by using both state and output feedback for a class of nonlinear multi-agent systems. The agents considered here are all identical upper-triangular no...This paper is concerned with the leader-follower consensus problem by using both state and output feedback for a class of nonlinear multi-agent systems. The agents considered here are all identical upper-triangular nonlinear systems which satisfy the Lipschitz growth condition. First, it is shown that the leader-follower consensus problem is equivalent to the control design problem of a high-dimensional multi-variable system.Second, by introducing an appropriate state transformation, the control design problem can be converted into the problem of finding a constant parameter, which can be obtained by solving the Lyapunov equation and estimating the nonlinear terms of the given system. At last, an example is given to verify effectiveness of the proposed consensus algorithms.展开更多
The performance of lithium-sulfur batteries is deteriorated by the inferior conductivity of sulfur,the shuttle effect of lithium polysulfides(LiPSs),sluggish redox kinetics of polysulfide intermediates and serious vol...The performance of lithium-sulfur batteries is deteriorated by the inferior conductivity of sulfur,the shuttle effect of lithium polysulfides(LiPSs),sluggish redox kinetics of polysulfide intermediates and serious volumetric expansion of sulfur.To overcome these challenges,we report a versatile route to prepare multi-functional nanocomposites with tuable hierarchical structure via ammonium hydroxide(NH_(3)·H_(2) O)induced self-assembly.The versatility of the system has been demonstrated that the organization of the hierarchical structure can be regulated by adding different amounts of NH_(3)·H_(2) O,and WS_(2) and Co_(9)S_(8) with nitrogen-doped carbon coating(denoted as WS_(2)@NC and Co_(9)S_(8)@NC)can be prepared by adding different precursor salts.When the as-prepared materials are applied for Li-S batteries,the WS_(2)@NC composite exhibits a reversible capacity of 1107.4 mAh g^(-1) at 0.1 C after 500 cycles and even 728.9 mAh g^(-1) at2 C for 1000 cycles,which is significantly better than the Co_(9)S_(8) counterpart and other reported WS_(2) sulfur hosts.Experimentally,the advantageous performance of WS_(2) could be attributed to its higher surface area and total pore volume,giving rise to the easier access to electrolyte and better ability to buffer the volume change during the charge/discharge process.Theoretically,the density function theory(DFT)calculation reveals that the as-prepared WS_(2) has a higher binding energy towards LiPSs as well as a lower energy barrier for Li^(+)diffusion on the surface than Co_(9)S_(8).More significantly,the density of states(DOS)analysis further confirms that the superior performance is mainly ascribed to the more prominent shifting and the more charge compensation from d band of W than Co,which increase electronic concentration and give more hybridization of d-p orbitals in the Fermi level of the adsorbed Li2 S4 to accelerate the lithium polysulfide interfacial redox and conversion dynamics in WS_(2).By proposing this mechanism,this work sheds new light on the understanding of catalytic conversion of lithium polysulfides at the atomic level and the strategy to develop advanced cathode materials for high-performance lithium-sulfur batteries.展开更多
The work presented in this paper was conducted to quantify the relationship between the pore characteristics and mechanical properties of white sandstone.The study include tests carried out under the coupling effects ...The work presented in this paper was conducted to quantify the relationship between the pore characteristics and mechanical properties of white sandstone.The study include tests carried out under the coupling effects of chemical corrosion,temperature,nuclear magnetic resonance,and mechanical tests.Computer fractal theory was employed to describe and quantify the characteristics of the growth of pores in white sandstone under the same coupling effect.A custom developed program code,in the MATLAB software platform,was used for calculating the growths of the pores in white sandstone when subjected to coupling effects.The correlation between the computer fractal dimension of the growth of the pores in rock and characteristics of mechanical damage was accordingly analyzed.The results showed that when the temperature was set at a level lower than 100°C,it caused damage to the rock and strength reduction,primarily due to the rates of chemical reactions,the generation,and evolution of pores in the rock mass under the coupling effects of chemical corrosion and temperature.Overall,it was observed that the higher the value of the computer fractal dimension,the higher the growth of the pores,and the lower the uniaxial compressive strength of the white sandstone.展开更多
Based on the Involvement Load Hypothesis, the present study investigated the differential effects of three post-listening output tasks(gap-filling, translation, and sentence-making) on immediate acquisition and retent...Based on the Involvement Load Hypothesis, the present study investigated the differential effects of three post-listening output tasks(gap-filling, translation, and sentence-making) on immediate acquisition and retention of such vocabulary dimensions as productive knowledge of orthography,receptive recall of meaning and form, and productive knowledge of grammatical functions. Ninety second-year English majors were divided into three groups to finish listening plus one of the postlistening tasks. The results showed that the post-listening output tasks had positive effects on immediate acquisition of productive vocabulary knowledge, partially in agreement with the Involvement Load Hypothesis. However, the effects on vocabulary knowledge retention were found to be largely inconsistent with the Involvement Load Hypothesis. The finding thus challenges this hypothesis in that involvement load is not the only determining factor and suggests that the theoretical construct of involvement load should be constructed with more caution.展开更多
This paper presents a novel fixed-time stabilization control(FSC)method for a class of strict-feedback nonlinear systems involving unmodelled system dynamics.The key feature of the proposed method is the design of two...This paper presents a novel fixed-time stabilization control(FSC)method for a class of strict-feedback nonlinear systems involving unmodelled system dynamics.The key feature of the proposed method is the design of two dynamic parameters.Specifically,a set of auxiliary variables is first introduced through state transformation.These variables combine the original system states and the two introduced dynamic parameters,facilitating the closed-loop system stability analyses.Then,the two dynamic parameters are delicately designed by utilizing the Lyapunov method,ensuring that all the closed-loop system states are globally fixed-time stable.Compared with existing results,the“explosion of complexity”problem of backstepping control is avoided.Moreover,the two designed dynamic parameters are dependent on system states rather than a time-varying function,thus the proposed controller is still valid beyond the given fixedtime convergence instant.The effectiveness of the proposed method is demonstrated through two practical systems.展开更多
More and more studies have demonstrated that pseudogenes possess coding ability,and the functions of their transcripts in the development of diseases have been partially revealed.However,the role of pseudogenes in mai...More and more studies have demonstrated that pseudogenes possess coding ability,and the functions of their transcripts in the development of diseases have been partially revealed.However,the role of pseudogenes in maintenance of normal physiological states and life activities has long been neglected.Here,we identify pseudogenes that are dynamically expressed during human early embryogenesis,showing different expression patterns from that of adult tissues.We explore the expression correlation between pseudogenes and the parent genes,partly due to their shared gene regulatory elements or the potential regulation network between them.The essential role of three pseudogenes,PI4KAP1,TMED10P1,and FBXW4P1,in maintaining self-renewal of human embryonic stem cells is demonstrated.We further find that the three pseudogenes might perform their regulatory functions by binding to proteins or microRNAs.The pseudogene-related single-nucleotide polymorphisms are significantly associated with human congenital disease,further illustrating their importance during early embryonic development.Overall,this study is an excavation and exploration of functional pseudogenes during early human embryonic development,suggesting that pseudogenes are not only capable of being specifically activated in pathological states,but also play crucial roles in the maintenance of normal physiological states.展开更多
Molecular dynamics simulation was employed to study the tensile behavior of single crystal titanium nanowires(NWs)with[112^-0],[1^-100] and[0001]orientations at different strain rates from 10^8s^-1 to 10^11s^-1.When...Molecular dynamics simulation was employed to study the tensile behavior of single crystal titanium nanowires(NWs)with[112^-0],[1^-100] and[0001]orientations at different strain rates from 10^8s^-1 to 10^11s^-1.When strain rates are above 10^10s^-1,the state transformation from HCP structure to amorphous state leads to super plasticity of Ti NWs,which is similar to FCC NWs.When strain rates are below 10^10s^-1,deformation mechanisms of Ti NWs show strong dependence on orientation.For [112^-0] orientated NW.{101^-1} compression twins(CTs)and the frequently activated transformation between CTs and deformation faults lead to higher plasticity than the other two orientated NWs.Besides,tensile deformation process along [112^-0] orientation is insensitive to strain rate.For [1^-100] orientated NW,prismaticslip is the main deformation mode at 10^8s^-1.As the strain rate increases,more types of dislocations are activated during plastic deformation process.For[0001]orientated NW,{101^-2} extension twinning is the main deformation mechanism,inducing the yield stress of [0001] orientated NW,which has the highest strain rate sensitivity.The number of initial nucleated twins increases while the saturation twin volume fraction decreases nonlinearly with increasing strain rate.展开更多
1 Introduction The fifth-generation(5G)era has already arrived and many applications are prospering.The multi‐ple input multiple output(MIMO)system is the key to enhancing channel capacity for both the fourthgenerati...1 Introduction The fifth-generation(5G)era has already arrived and many applications are prospering.The multi‐ple input multiple output(MIMO)system is the key to enhancing channel capacity for both the fourthgeneration(4G)wireless communication and 5G sys‐tems.For a smartphone,the most challenging task for antenna engineers is to accommodate the numerous 4G and 5G multi-port antennas while avoiding mutual coupling problems(Li Y et al.,2009,2012;Hong,2017;Sharawi et al.,2017).Therefore,implementing multiple antennas within a small space is a worth‐while topic to study,especially for antennas operat‐ing at the same frequency。展开更多
This study examined the effects of either listening or reading input on 88 first-year non- English-ma)or Chinese university EFL students' incidental acquisition in vocabulary form, meaning and production. The studen...This study examined the effects of either listening or reading input on 88 first-year non- English-ma)or Chinese university EFL students' incidental acquisition in vocabulary form, meaning and production. The students were put into a Listening Group (n = 47) and a Reading Group (n = 41), each of which finished either two listening activities (each consisting of a dialogic text and an information transfer task) or two reading activities (each consisting of a reading text and five multiple-choice questions). The four texts all contained five low- frequency target words which a revised Vocabulary Knowledge Test had shown to be only slightly known by the participants before the activities. The results of the post-tests showed that the Reading Group had general acquisition advantage over the Listening Group in terms of all the three vocabulary aspects, and due to the fact of rich target word contexts and repeated access to the texts, the Listening Group manifested vocabulary meaning acquisition nearly equal to the Reading Group. Overall, the study shows the notably advantageous effects of reading input on incidental vocabulary acquisition, and concerning facilitating vocabulary acquisition through listening, it points out the importance of increasing opportunities for learners to process listening input with rich contextual clues through task repetition.展开更多
The rapid increase in the artificial syntheses of organic pollutants has raised widespread concern.However,the mechanisms by which fungi degrade these new organic pollutants in the environment and adapt to environment...The rapid increase in the artificial syntheses of organic pollutants has raised widespread concern.However,the mechanisms by which fungi degrade these new organic pollutants in the environment and adapt to environmental stressors remain unclear.In this study,Phanerochaete chrysosporium,a model white rot fungus,was used to explore the interfacial processes and mechanisms for synergistic degradation of 4,4′-dichlorobiphenyl(PCB15)with magnetite nanoparticles.The results showed that after 3 and 5 days of cultivation with Phanerochaete chrysosporium alone,the rates for PCB15 degradation were 32%and 65%,respectively,indicating that the white rot fungus itself was able to degrade the organic pollutant.Moreover,the addition of magnetite nanoparticles significantly enhanced the degradation of PCB15 by Phanerochaete chrysosporium.After cocultivation for 3 and 5 days,the rates for PCB15 degradation increased to 42%and 84%,respectively.Synchrotron radiation-based Fourier transform infrared spectromicroscopy(SR-FTIR)showed that the magnetite particles were tightly adhered to the fungal hyphae and were unevenly distributed on the hyphal surfaces.Furthermore,cocultivation of the fungus and magnetite nanoparticles significantly enhanced the nanozymatic activity of magnetite.A linear regression model provided a significantly negative correlation(r=−0.96,p<0.001)between the nanozymatic activity of the magnetite and the concentration ratio of the PCB15,supporting the hypothesis that white rot fungi degraded the PCB15 by enhancing the nanozyme activity of magnetite.High-resolution X-ray photoelectron spectroscopy(XPS)revealed that the nanozymatic activity of magnetite was mainly governed by oxygen vacancies on the mineral surfaces rather than the iron valence.Together,these findings increase our understanding of the powerful capabilities of fungi in terms of stress resistance and adaptation to extreme environments and provide new insights into fungal-mediated degradation of organic pollutants for soil remediation in contaminated sites.展开更多
In plants,the genome structure of hybrids changes compared with their parents,but the effects of these changes in hybrids remain elusive.Comparing reciprocal crosses between Col×C24 and C24×Col in Arabidopsi...In plants,the genome structure of hybrids changes compared with their parents,but the effects of these changes in hybrids remain elusive.Comparing reciprocal crosses between Col×C24 and C24×Col in Arabidopsis using high-throughput chromosome conformation capture assay(Hi-C)analysis,we found that hybrid three-dimensional(3D)chromatin organization had more long-distance interactions relative to parents,and this was mainly located in promoter regions and enriched in genes with heterosis-related pathways.The interactions between euchromatin and heterochromatin were increased,and the compartment strength decreased in hybrids.In compartment domain(CD)boundaries,the distal interactions were more in hybrids than their parents.In the hybrids of CURLY LEAF(clf)mutants clfCol×clfC24and clfC24×clfCol,the heterosis phenotype was damaged,and the long-distance interactions in hybrids were fewer than in their parents with lower H3K27me3.ChIP-seq data revealed higher levels of H3K27me3 in the region adjacent to the CD boundary and the same interactional homo-trans sites in the wild-type(WT)hybrids,which may have led to more long-distance interactions.In addition,the differentially expressed genes(DEGs)located in the boundaries of CDs and loop regions changed obviously in WT,and the functional enrichment for DEGs was different between WT and clf in the longdistance interactions and loop regions.Our findings may therefore propose a new epigenetic explanation of heterosis in the Arabidopsis hybrids and provide new insights into crop breeding and yield increase.展开更多
Here,we report a concise and divergent enantioselective total synthesis of marine sesquiterpene quinone meroterpenoids(+)-dysidavarones A–C(1–3)using predysidavarone 6 as a key common intermediate.The highly straine...Here,we report a concise and divergent enantioselective total synthesis of marine sesquiterpene quinone meroterpenoids(+)-dysidavarones A–C(1–3)using predysidavarone 6 as a key common intermediate.The highly strained and bridged eight-membered carbocycle of predysidavarone 6 was constructed by a one-pot intermolecular alkylation and intramolecular arylation of Wieland–Miescher ketone derivative 11 and benzyl bromide 12.The total synthesis of(+)-dysidavarones A–C(1–3)was achieved from predysidavarone 6 in a divergent manner by a late-stage introduction of the ethoxy group,which reveals the possible source of the ethoxy group within(+)-dysidavarones A–C(1–3)and provides a late-stage modifiable route for the synthesis of dysidavarone analogs for further anti-cancer activity evaluation.展开更多
To the Editor:The discovery of the induced pluripotent stem cells(iPSCs)by Takahashi and Yamanaka in 2006 was hailed as a major breakthrough in stem cell research.And a large number of experimental studies have proven...To the Editor:The discovery of the induced pluripotent stem cells(iPSCs)by Takahashi and Yamanaka in 2006 was hailed as a major breakthrough in stem cell research.And a large number of experimental studies have proven that the transforming growth factor-β(TGF-β)signaling pathway is a key signaling pathway in iPSC reprogramming.The TGF-βsignaling pathway can promote or inhibit iPSC reprogramming under different conditions[Figure 1].This article describes the role of the TGF-βsignaling pathway in iPSC reprogramming.展开更多
What is already known about this topic?Recently,tick-borne pathogens transmitted through blood transfusions have posed new risks to blood safety.What is added by this report?We developed a quality control system for n...What is already known about this topic?Recently,tick-borne pathogens transmitted through blood transfusions have posed new risks to blood safety.What is added by this report?We developed a quality control system for nucleic acid testing(NAT)for Babesia,Borrelia burgdorferi,and Anaplasma phagocytophilum,evaluated five Triplex-NAT kits,and conducted external quality assessments of blood centers.This study screened 92,700 blood donors from Heilongjiang,Inner Mongolia,and Xinjiang provincial-level administrative divisions during 2022–2023.A donor in Hegang,Heilongjiang,tested positive for Borrelia burgdorferi,marking the first detection of this infection in Chinese blood donors.What are the implications for public health practice?Quality control of NAT is vital for managing tickborne pathogen outbreaks.To ensure blood transfusion safety,screening should be strengthened in high-risk areas outside national borders.展开更多
Greenwashing behaviors(GWBs)in green finance products(GFPs)by enterprises seriously hinder the realization of environmental protection goals.However,methods for effectively regulating GWBs in GFPs are unclear.This stu...Greenwashing behaviors(GWBs)in green finance products(GFPs)by enterprises seriously hinder the realization of environmental protection goals.However,methods for effectively regulating GWBs in GFPs are unclear.This study constructed a tripartite evolutionary game model to analyze the formation and governance mechanisms of GWBs in GFPs among regulatory authorities,enterprises,and investors.Subsequently,the stability equilibrium strategy and key factors influencing the system equilibrium were discussed.Several interesting conclusions were drawn.First,we demonstrated that an interdependence mechanism exists among three game agents who mutually influence each other.The larger the probability of regulatory authorities choosing active supervision and investors adopting feedback,the more enterprises are willing to carry out green projects.Second,three corresponding governance modes for GWBs were put forward following the developmental stages of GFPs.Among these,the collaboration mode is the most effective in incentivizing enterprises to implement green projects.Third,based on sensitivity simulations,the initial willingness of the tripartite stakeholders,investor feedback cost,investor compensation,the penalty for greenwashing enterprises,and the reputational benefit of enterprises are critical factors that influence evolutionary results.Finally,targeted countermeasures were provided for regulatory authorities to prevent enterprises from engaging in GWBs.展开更多
RNA-binding proteins(RBPs)are widely involved in the transcriptional and posttranscriptional regulation of multiple biological processes.The transcriptional regulatory ability of RBPs was indicated by the identificati...RNA-binding proteins(RBPs)are widely involved in the transcriptional and posttranscriptional regulation of multiple biological processes.The transcriptional regulatory ability of RBPs was indicated by the identification of chromatin-enriched RBPs(Che-RBPs).One of these proteins,KH-type splicing regulatory protein(KHSRP),is a multifunctional RBP that has been implicated in mRNA decay,alternative splicing,and miRNA biogenesis and plays an essential role in myeloid differentiation by facilitating the maturation of miR-129.In this study,we revealed that KHSRP regulates monocytic differentiation by regulating gene transcription and RNA splicing.KHSRP-occupied specific genomic sites in promoter and enhancer regions to regulate the expression of several hematopoietic genes through transcriptional activation and bound to pre-mRNA intronic regions to modulate alternative splicing during monocytic differentiation.Of note,KHSRP had co-regulatory effects at both the transcriptional and posttranscriptional levels on MOGOH and ADARB1.Taken together,our analyses revealed the dual DNA-and RNA-binding activities of KHSRP and have provided a paradigm to guide the analysis of other functional Che-RBPs in different biological systems.展开更多
基金This research was supported financially by the NNSFC(41774088,41331066,42104084,and 41474059)the Key Research Program of Frontier Sciences CAS(Chinese Academy of Sciences)(QYZDY-SSW-SYS003)。
文摘Global mean sea level(GMSL) change is one of the important indicators of global climate change and is a crucial scientific issue of continuing interest. As satellite altimeter data, the Gravity Recovery and Climate Experiment(GRACE) and Argo continue to be updated, especially with the release of GRACE Follow-On(GRACE-FO) data, making it necessary to combine these latest data to estimate sea level change. Determinations on whether the GRACE and GRACE-FO observation systems provide unbiased global observation data have not been effectively evaluated. Therefore, this research mainly investigated the consistency of GRACE and GRACE-FO observation data in studying GMSL change. By comparing the sum of the GMSL calculated by the two gravity satellites and Argo data with the GMSL calculated by satellite altimeters, the discrepancy between GRACE-FO + Argo and satellite altimeter data is about 7.9 ± 2.3 mm, which is likely derived from the inconsistency between GRACE and GRACE-FO data.
基金the financial support from the National Natural Science Foundation of China(Nos.51975271,51675260,51475223)the Starting Research Fund of Nanjing Vocational University of Industry Technology,China(No.YK20-14-05)。
文摘The low cycle fatigue behavior of zirconium−titanium−steel composite plate under symmetrical and asymmetric stress control was studied.The effects of mean stress and stress amplitude on cyclic deformation,ratcheting effect and damage mechanism were discussed in detail.The results show that under symmetric stress control,the forward ratcheting deformation is observed.Under asymmetric stress control,the ratcheting strain increases rapidly with mean stress and stress amplitude increasing.Under high stress amplitude,the influence of mean stress is more significant.In addition,by studying the variation of strain energy density,it is found that the stress amplitude mainly promotes the fatigue damage,while the mean stress leads to the ratcheting damage.In addition,fractographic observation shows that the crack initiates in the brittle metal compound at the interface,and the steel has higher resistance to crack propagation.Finally,the accuracy of life prediction model considering ratcheting effect is discussed in detail,and a high-precision life prediction model directly based on mean stress and stress amplitude is proposed.
文摘This paper is concerned with the leader-follower consensus problem by using both state and output feedback for a class of nonlinear multi-agent systems. The agents considered here are all identical upper-triangular nonlinear systems which satisfy the Lipschitz growth condition. First, it is shown that the leader-follower consensus problem is equivalent to the control design problem of a high-dimensional multi-variable system.Second, by introducing an appropriate state transformation, the control design problem can be converted into the problem of finding a constant parameter, which can be obtained by solving the Lyapunov equation and estimating the nonlinear terms of the given system. At last, an example is given to verify effectiveness of the proposed consensus algorithms.
基金financially supported by National Key Research and Development Program(2018YFB1502503)Fundamental Research Funds for the Central Universities(ZYGX2019J030)Sichuan Science and Technology Program(2020YJ0299)。
文摘The performance of lithium-sulfur batteries is deteriorated by the inferior conductivity of sulfur,the shuttle effect of lithium polysulfides(LiPSs),sluggish redox kinetics of polysulfide intermediates and serious volumetric expansion of sulfur.To overcome these challenges,we report a versatile route to prepare multi-functional nanocomposites with tuable hierarchical structure via ammonium hydroxide(NH_(3)·H_(2) O)induced self-assembly.The versatility of the system has been demonstrated that the organization of the hierarchical structure can be regulated by adding different amounts of NH_(3)·H_(2) O,and WS_(2) and Co_(9)S_(8) with nitrogen-doped carbon coating(denoted as WS_(2)@NC and Co_(9)S_(8)@NC)can be prepared by adding different precursor salts.When the as-prepared materials are applied for Li-S batteries,the WS_(2)@NC composite exhibits a reversible capacity of 1107.4 mAh g^(-1) at 0.1 C after 500 cycles and even 728.9 mAh g^(-1) at2 C for 1000 cycles,which is significantly better than the Co_(9)S_(8) counterpart and other reported WS_(2) sulfur hosts.Experimentally,the advantageous performance of WS_(2) could be attributed to its higher surface area and total pore volume,giving rise to the easier access to electrolyte and better ability to buffer the volume change during the charge/discharge process.Theoretically,the density function theory(DFT)calculation reveals that the as-prepared WS_(2) has a higher binding energy towards LiPSs as well as a lower energy barrier for Li^(+)diffusion on the surface than Co_(9)S_(8).More significantly,the density of states(DOS)analysis further confirms that the superior performance is mainly ascribed to the more prominent shifting and the more charge compensation from d band of W than Co,which increase electronic concentration and give more hybridization of d-p orbitals in the Fermi level of the adsorbed Li2 S4 to accelerate the lithium polysulfide interfacial redox and conversion dynamics in WS_(2).By proposing this mechanism,this work sheds new light on the understanding of catalytic conversion of lithium polysulfides at the atomic level and the strategy to develop advanced cathode materials for high-performance lithium-sulfur batteries.
基金This work was supported by the National Natural Science Foundation of China(51674149)the Natural Science Foundation of Shandong Province(ZR2018PEE005)+1 种基金the Research Fund of the State Key Laboratory of Coal Resources and Safe Mining(SKLCRSM19KF015)the Research Fund of the Key Laboratory of Mine Disaster Prevention and Control of the Ministry of Education(MDPC201915).
文摘The work presented in this paper was conducted to quantify the relationship between the pore characteristics and mechanical properties of white sandstone.The study include tests carried out under the coupling effects of chemical corrosion,temperature,nuclear magnetic resonance,and mechanical tests.Computer fractal theory was employed to describe and quantify the characteristics of the growth of pores in white sandstone under the same coupling effect.A custom developed program code,in the MATLAB software platform,was used for calculating the growths of the pores in white sandstone when subjected to coupling effects.The correlation between the computer fractal dimension of the growth of the pores in rock and characteristics of mechanical damage was accordingly analyzed.The results showed that when the temperature was set at a level lower than 100°C,it caused damage to the rock and strength reduction,primarily due to the rates of chemical reactions,the generation,and evolution of pores in the rock mass under the coupling effects of chemical corrosion and temperature.Overall,it was observed that the higher the value of the computer fractal dimension,the higher the growth of the pores,and the lower the uniaxial compressive strength of the white sandstone.
文摘Based on the Involvement Load Hypothesis, the present study investigated the differential effects of three post-listening output tasks(gap-filling, translation, and sentence-making) on immediate acquisition and retention of such vocabulary dimensions as productive knowledge of orthography,receptive recall of meaning and form, and productive knowledge of grammatical functions. Ninety second-year English majors were divided into three groups to finish listening plus one of the postlistening tasks. The results showed that the post-listening output tasks had positive effects on immediate acquisition of productive vocabulary knowledge, partially in agreement with the Involvement Load Hypothesis. However, the effects on vocabulary knowledge retention were found to be largely inconsistent with the Involvement Load Hypothesis. The finding thus challenges this hypothesis in that involvement load is not the only determining factor and suggests that the theoretical construct of involvement load should be constructed with more caution.
基金supported by the National Natural Science Foundation of China(61821004,U1964207,20221017-10)。
文摘This paper presents a novel fixed-time stabilization control(FSC)method for a class of strict-feedback nonlinear systems involving unmodelled system dynamics.The key feature of the proposed method is the design of two dynamic parameters.Specifically,a set of auxiliary variables is first introduced through state transformation.These variables combine the original system states and the two introduced dynamic parameters,facilitating the closed-loop system stability analyses.Then,the two dynamic parameters are delicately designed by utilizing the Lyapunov method,ensuring that all the closed-loop system states are globally fixed-time stable.Compared with existing results,the“explosion of complexity”problem of backstepping control is avoided.Moreover,the two designed dynamic parameters are dependent on system states rather than a time-varying function,thus the proposed controller is still valid beyond the given fixedtime convergence instant.The effectiveness of the proposed method is demonstrated through two practical systems.
基金supported by the National Key Research and Development Program of China(2021YFA0805703,2019YFA0801800,and 2019YFA0802600)the National Natural Science Foundation of China(82330007,82122005,92268205 and 81970101)+1 种基金CAMS Innovation Fund for Medical Sciences(2021-I2M1-019)Haihe Laboratory of Cell Ecosystem Innovation Fund(22HHXBSS00027)。
文摘More and more studies have demonstrated that pseudogenes possess coding ability,and the functions of their transcripts in the development of diseases have been partially revealed.However,the role of pseudogenes in maintenance of normal physiological states and life activities has long been neglected.Here,we identify pseudogenes that are dynamically expressed during human early embryogenesis,showing different expression patterns from that of adult tissues.We explore the expression correlation between pseudogenes and the parent genes,partly due to their shared gene regulatory elements or the potential regulation network between them.The essential role of three pseudogenes,PI4KAP1,TMED10P1,and FBXW4P1,in maintaining self-renewal of human embryonic stem cells is demonstrated.We further find that the three pseudogenes might perform their regulatory functions by binding to proteins or microRNAs.The pseudogene-related single-nucleotide polymorphisms are significantly associated with human congenital disease,further illustrating their importance during early embryonic development.Overall,this study is an excavation and exploration of functional pseudogenes during early human embryonic development,suggesting that pseudogenes are not only capable of being specifically activated in pathological states,but also play crucial roles in the maintenance of normal physiological states.
基金the financial supports of the National Natural Science Foundation of China (Nos.51475223,51675260)the Graduate Student Scientific Innovative Project of Jiangsu Province (No.KYLX16 0595)
文摘Molecular dynamics simulation was employed to study the tensile behavior of single crystal titanium nanowires(NWs)with[112^-0],[1^-100] and[0001]orientations at different strain rates from 10^8s^-1 to 10^11s^-1.When strain rates are above 10^10s^-1,the state transformation from HCP structure to amorphous state leads to super plasticity of Ti NWs,which is similar to FCC NWs.When strain rates are below 10^10s^-1,deformation mechanisms of Ti NWs show strong dependence on orientation.For [112^-0] orientated NW.{101^-1} compression twins(CTs)and the frequently activated transformation between CTs and deformation faults lead to higher plasticity than the other two orientated NWs.Besides,tensile deformation process along [112^-0] orientation is insensitive to strain rate.For [1^-100] orientated NW,prismaticslip is the main deformation mode at 10^8s^-1.As the strain rate increases,more types of dislocations are activated during plastic deformation process.For[0001]orientated NW,{101^-2} extension twinning is the main deformation mechanism,inducing the yield stress of [0001] orientated NW,which has the highest strain rate sensitivity.The number of initial nucleated twins increases while the saturation twin volume fraction decreases nonlinearly with increasing strain rate.
基金the National Natural Science Foundation of China(No.62101427)the Key Research and Development Project of Shaanxi Province,China(No.2022GY-095)+1 种基金the High-Level Innovation Talent Project Imported by Qinchuangyuan of Shaanxi Province,China(No.QCYRCXM-2022-33)the Shaanxi Key Laboratory of Deep Space Exploration Intelligent Information Technology(No.2021SYS-04)。
文摘1 Introduction The fifth-generation(5G)era has already arrived and many applications are prospering.The multi‐ple input multiple output(MIMO)system is the key to enhancing channel capacity for both the fourthgeneration(4G)wireless communication and 5G sys‐tems.For a smartphone,the most challenging task for antenna engineers is to accommodate the numerous 4G and 5G multi-port antennas while avoiding mutual coupling problems(Li Y et al.,2009,2012;Hong,2017;Sharawi et al.,2017).Therefore,implementing multiple antennas within a small space is a worth‐while topic to study,especially for antennas operat‐ing at the same frequency。
文摘This study examined the effects of either listening or reading input on 88 first-year non- English-ma)or Chinese university EFL students' incidental acquisition in vocabulary form, meaning and production. The students were put into a Listening Group (n = 47) and a Reading Group (n = 41), each of which finished either two listening activities (each consisting of a dialogic text and an information transfer task) or two reading activities (each consisting of a reading text and five multiple-choice questions). The four texts all contained five low- frequency target words which a revised Vocabulary Knowledge Test had shown to be only slightly known by the participants before the activities. The results of the post-tests showed that the Reading Group had general acquisition advantage over the Listening Group in terms of all the three vocabulary aspects, and due to the fact of rich target word contexts and repeated access to the texts, the Listening Group manifested vocabulary meaning acquisition nearly equal to the Reading Group. Overall, the study shows the notably advantageous effects of reading input on incidental vocabulary acquisition, and concerning facilitating vocabulary acquisition through listening, it points out the importance of increasing opportunities for learners to process listening input with rich contextual clues through task repetition.
基金supported by the National Key Basic Research Program of China(Grant No.2022YFC3701401)the National Natural Science Foundation of China(Grant Nos.U22A20608 and 41977271)Self-Dependent Innovation Foundation of Tianjin University(Grant No.2023XJC-0014).
文摘The rapid increase in the artificial syntheses of organic pollutants has raised widespread concern.However,the mechanisms by which fungi degrade these new organic pollutants in the environment and adapt to environmental stressors remain unclear.In this study,Phanerochaete chrysosporium,a model white rot fungus,was used to explore the interfacial processes and mechanisms for synergistic degradation of 4,4′-dichlorobiphenyl(PCB15)with magnetite nanoparticles.The results showed that after 3 and 5 days of cultivation with Phanerochaete chrysosporium alone,the rates for PCB15 degradation were 32%and 65%,respectively,indicating that the white rot fungus itself was able to degrade the organic pollutant.Moreover,the addition of magnetite nanoparticles significantly enhanced the degradation of PCB15 by Phanerochaete chrysosporium.After cocultivation for 3 and 5 days,the rates for PCB15 degradation increased to 42%and 84%,respectively.Synchrotron radiation-based Fourier transform infrared spectromicroscopy(SR-FTIR)showed that the magnetite particles were tightly adhered to the fungal hyphae and were unevenly distributed on the hyphal surfaces.Furthermore,cocultivation of the fungus and magnetite nanoparticles significantly enhanced the nanozymatic activity of magnetite.A linear regression model provided a significantly negative correlation(r=−0.96,p<0.001)between the nanozymatic activity of the magnetite and the concentration ratio of the PCB15,supporting the hypothesis that white rot fungi degraded the PCB15 by enhancing the nanozyme activity of magnetite.High-resolution X-ray photoelectron spectroscopy(XPS)revealed that the nanozymatic activity of magnetite was mainly governed by oxygen vacancies on the mineral surfaces rather than the iron valence.Together,these findings increase our understanding of the powerful capabilities of fungi in terms of stress resistance and adaptation to extreme environments and provide new insights into fungal-mediated degradation of organic pollutants for soil remediation in contaminated sites.
基金supported by the Key Program of National Natural Science Foundation of China(32230006 to D.X.W.)the Shandong Development Fund of Science&Technology+2 种基金the Award of Natural Science Foundation of Shandong Province(ZR2021ZD30)China Postdoctoral Science Foundation(8206300443)Boya Postdoctoral Program of Peking University。
文摘In plants,the genome structure of hybrids changes compared with their parents,but the effects of these changes in hybrids remain elusive.Comparing reciprocal crosses between Col×C24 and C24×Col in Arabidopsis using high-throughput chromosome conformation capture assay(Hi-C)analysis,we found that hybrid three-dimensional(3D)chromatin organization had more long-distance interactions relative to parents,and this was mainly located in promoter regions and enriched in genes with heterosis-related pathways.The interactions between euchromatin and heterochromatin were increased,and the compartment strength decreased in hybrids.In compartment domain(CD)boundaries,the distal interactions were more in hybrids than their parents.In the hybrids of CURLY LEAF(clf)mutants clfCol×clfC24and clfC24×clfCol,the heterosis phenotype was damaged,and the long-distance interactions in hybrids were fewer than in their parents with lower H3K27me3.ChIP-seq data revealed higher levels of H3K27me3 in the region adjacent to the CD boundary and the same interactional homo-trans sites in the wild-type(WT)hybrids,which may have led to more long-distance interactions.In addition,the differentially expressed genes(DEGs)located in the boundaries of CDs and loop regions changed obviously in WT,and the functional enrichment for DEGs was different between WT and clf in the longdistance interactions and loop regions.Our findings may therefore propose a new epigenetic explanation of heterosis in the Arabidopsis hybrids and provide new insights into crop breeding and yield increase.
基金financially supported by the National Natural Science Foundation of China(Nos.22171146,21971121,and 22188101 to ZL)the China Postdoctoral Science Foundation(No.2021M701775 to CC)。
文摘Here,we report a concise and divergent enantioselective total synthesis of marine sesquiterpene quinone meroterpenoids(+)-dysidavarones A–C(1–3)using predysidavarone 6 as a key common intermediate.The highly strained and bridged eight-membered carbocycle of predysidavarone 6 was constructed by a one-pot intermolecular alkylation and intramolecular arylation of Wieland–Miescher ketone derivative 11 and benzyl bromide 12.The total synthesis of(+)-dysidavarones A–C(1–3)was achieved from predysidavarone 6 in a divergent manner by a late-stage introduction of the ethoxy group,which reveals the possible source of the ethoxy group within(+)-dysidavarones A–C(1–3)and provides a late-stage modifiable route for the synthesis of dysidavarone analogs for further anti-cancer activity evaluation.
基金supported by grants from the Key Projects in Yunnan Province(No.202301AY070001-034)the Project of the Yunnan Provincial Department of Education(No.2023Y0827)
文摘To the Editor:The discovery of the induced pluripotent stem cells(iPSCs)by Takahashi and Yamanaka in 2006 was hailed as a major breakthrough in stem cell research.And a large number of experimental studies have proven that the transforming growth factor-β(TGF-β)signaling pathway is a key signaling pathway in iPSC reprogramming.The TGF-βsignaling pathway can promote or inhibit iPSC reprogramming under different conditions[Figure 1].This article describes the role of the TGF-βsignaling pathway in iPSC reprogramming.
基金Supported by the National High Level Hospital Clinical Research Funding(BJ-2022-182)CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-060).
文摘What is already known about this topic?Recently,tick-borne pathogens transmitted through blood transfusions have posed new risks to blood safety.What is added by this report?We developed a quality control system for nucleic acid testing(NAT)for Babesia,Borrelia burgdorferi,and Anaplasma phagocytophilum,evaluated five Triplex-NAT kits,and conducted external quality assessments of blood centers.This study screened 92,700 blood donors from Heilongjiang,Inner Mongolia,and Xinjiang provincial-level administrative divisions during 2022–2023.A donor in Hegang,Heilongjiang,tested positive for Borrelia burgdorferi,marking the first detection of this infection in Chinese blood donors.What are the implications for public health practice?Quality control of NAT is vital for managing tickborne pathogen outbreaks.To ensure blood transfusion safety,screening should be strengthened in high-risk areas outside national borders.
基金Supports from the National Natural Science Foundation of China under Grant Nos.72348003,72022020 and 71974181the National Social Science Foundation of China under Grant No.20BJL058 are acknowledged.
文摘Greenwashing behaviors(GWBs)in green finance products(GFPs)by enterprises seriously hinder the realization of environmental protection goals.However,methods for effectively regulating GWBs in GFPs are unclear.This study constructed a tripartite evolutionary game model to analyze the formation and governance mechanisms of GWBs in GFPs among regulatory authorities,enterprises,and investors.Subsequently,the stability equilibrium strategy and key factors influencing the system equilibrium were discussed.Several interesting conclusions were drawn.First,we demonstrated that an interdependence mechanism exists among three game agents who mutually influence each other.The larger the probability of regulatory authorities choosing active supervision and investors adopting feedback,the more enterprises are willing to carry out green projects.Second,three corresponding governance modes for GWBs were put forward following the developmental stages of GFPs.Among these,the collaboration mode is the most effective in incentivizing enterprises to implement green projects.Third,based on sensitivity simulations,the initial willingness of the tripartite stakeholders,investor feedback cost,investor compensation,the penalty for greenwashing enterprises,and the reputational benefit of enterprises are critical factors that influence evolutionary results.Finally,targeted countermeasures were provided for regulatory authorities to prevent enterprises from engaging in GWBs.
基金This work was supported by the National Key Research and Development Program of China(2019YFA0801800,2021YFA1102400,2019YFA0802600 and 2021YFA0805703)the National Natural Science Foundation of China(81530007,31900072,31725013,82022001,82122005,81970103 and 81970101)CAMS Innovation Fund for Medical Sciences[2021-I2M-1-019 and 2021-I2M-1-040].
文摘RNA-binding proteins(RBPs)are widely involved in the transcriptional and posttranscriptional regulation of multiple biological processes.The transcriptional regulatory ability of RBPs was indicated by the identification of chromatin-enriched RBPs(Che-RBPs).One of these proteins,KH-type splicing regulatory protein(KHSRP),is a multifunctional RBP that has been implicated in mRNA decay,alternative splicing,and miRNA biogenesis and plays an essential role in myeloid differentiation by facilitating the maturation of miR-129.In this study,we revealed that KHSRP regulates monocytic differentiation by regulating gene transcription and RNA splicing.KHSRP-occupied specific genomic sites in promoter and enhancer regions to regulate the expression of several hematopoietic genes through transcriptional activation and bound to pre-mRNA intronic regions to modulate alternative splicing during monocytic differentiation.Of note,KHSRP had co-regulatory effects at both the transcriptional and posttranscriptional levels on MOGOH and ADARB1.Taken together,our analyses revealed the dual DNA-and RNA-binding activities of KHSRP and have provided a paradigm to guide the analysis of other functional Che-RBPs in different biological systems.