目的 评价iRoot BP Plus用于乳磨牙牙髓切断术的临床疗效。方法 选取因龋坏就诊儿童口腔科的患儿89名,下颌乳磨牙120颗,随机分为两组,分别采用iRoot BP Plus和三氧化矿物凝集体(MTA)作为盖髓剂,行牙髓切断术,术后3、6、12个月复查,通过...目的 评价iRoot BP Plus用于乳磨牙牙髓切断术的临床疗效。方法 选取因龋坏就诊儿童口腔科的患儿89名,下颌乳磨牙120颗,随机分为两组,分别采用iRoot BP Plus和三氧化矿物凝集体(MTA)作为盖髓剂,行牙髓切断术,术后3、6、12个月复查,通过临床及X线片检查进行疗效评价。结果 iRoot BP Plus和MTA作为盖髓剂,牙髓切断术后1年临床疗效观察,iRoot BP Plus组60例中,失访5例,成功50例,失败5例,成功率90.9%,对照组MTA组60例中,失访5例,成功46例,失败9例,成功率83.6%,两组间无统计学差异(P> 0.05)。结论 iRoot BP Plus用于乳磨牙牙髓切断术取得了良好的临床效果,临床操作简单且不引起牙冠变色,具有良好的应用前景。展开更多
目的观察iRoot BP Plus作为盖髓剂,用于小型猪乳前磨牙牙髓切断术后牙髓的组织学变化,探讨i Root BP Plus广泛应用于临床的可行性。方法选用4只5月龄小型猪,选取双侧上下颌乳前磨牙共32颗,行牙髓切断术。随机选择一侧乳前磨牙为实验组,...目的观察iRoot BP Plus作为盖髓剂,用于小型猪乳前磨牙牙髓切断术后牙髓的组织学变化,探讨i Root BP Plus广泛应用于临床的可行性。方法选用4只5月龄小型猪,选取双侧上下颌乳前磨牙共32颗,行牙髓切断术。随机选择一侧乳前磨牙为实验组,采用iRoot BP Plus作为盖髓剂,另一侧为对照组,采用MTA作为盖髓剂,分别于术后2、4、8、12周处死动物。切取含实验牙的上下颌骨块,进行标本固定和HE染色,观察术后牙髓组织病理学变化。结果i Root BP Plus和MTA均可促进修复性牙本质形成,iRoot BP Plus盖髓后形成修复性牙本质较MTA早,术后8周可见牙本质桥形成,术后12周的牙本质桥形态较规则。二者均未引起浅表牙髓组织坏死,牙本质桥下方的牙髓组织表面在术后4周可见慢性炎症,术后8周炎症基本消失。结论在小型猪乳牙牙髓切断术中,使用iRoot BP Plus盖髓后12周可以形成与MTA盖髓相似的、形态较好的牙本质桥,且牙髓状态良好,为MTA临床良好替代的盖髓剂。展开更多
目的分析全身性与腹腔内联合双向化疗在进展期胃癌患者根治术后腹膜复发转移中的应用效果及生存获益情况。方法回顾性选取2018年1月至2020年12月安徽医科大学附属六安医院收治的106例进展期胃癌根治术后腹膜复发转移患者的临床资料,根...目的分析全身性与腹腔内联合双向化疗在进展期胃癌患者根治术后腹膜复发转移中的应用效果及生存获益情况。方法回顾性选取2018年1月至2020年12月安徽医科大学附属六安医院收治的106例进展期胃癌根治术后腹膜复发转移患者的临床资料,根据化疗方式的不同进行分组,接受腹腔内联合双向化疗的57例患者纳入观察组,接受全身性化疗的49例患者纳入对照组。比较两组患者腹膜癌指数(peritoneal cancer index,PCI)评分、毒副反应、生活质量及生存获益情况。结果化疗后,观察组PCI评分低于对照组,差异有统计学意义(P<0.05);两组患者毒副反应差异无统计学意义(P>0.05);观察组化疗后症状、躯体和情绪功能、整体生活质量和单项测量项目评分均高于对照组(P<0.05);观察组2年生存率(38.60%)高于对照组(18.37%),差异有统计学意义(P<0.05);观察组中位无复发生存时间为15个月,对照组为8个月,差异有统计学意义(P<0.05)。结论相比于全身性化疗,将腹腔内联合双向化疗应用于进展期胃癌患者根治术后腹膜复发转移的治疗中,可提高生存率和生活质量,延长无复发生存时间,未明显增加毒副反应。展开更多
In this study,the effects of intermetallic compounds(Mg_(17)Al_(12)and Al_(8)Mn_(5))on the Mg-Al layered double hydroxide(LDH)formation mechanism and corrosion behavior of an in-situ LDH/Mg(OH)_(2)steam coatings on AZ...In this study,the effects of intermetallic compounds(Mg_(17)Al_(12)and Al_(8)Mn_(5))on the Mg-Al layered double hydroxide(LDH)formation mechanism and corrosion behavior of an in-situ LDH/Mg(OH)_(2)steam coatings on AZ80 Mg alloy were investigated.Citric acid(CA)was used to activate the alloy surface during the pretreatment process.The alloy was first pretreated with CA and then subjected to a hydrothermal process using ultrapure water to produce Mg-Al-LDH/Mg(OH)_(2)steam coating.The effect of different time of acid pretreatment on the activation of the intermetallic compounds was investigated.The microstructure and elemental composition of the obtained coatings were analyzed using FE-SEM,EDS,XRD and FT-IR.The corrosion resistance of the coated samples was evaluated using different techniques,i.e.,potentiodynamic polarization(PDP),electrochemical impedance spectrum(EIS)and hydrogen evolution test.The results indicated that the CA pretreatment significantly influenced the activity of the alloy surface by exposing the intermetallic compounds.The surface area fraction of Mg_(17)Al_(12)and Al_(8)Mn_(5)phases on the surface of the alloy was significantly higher after the CA pretreatment,and thus promoted the growth of the subsequent Mg-Al-LDH coatings.The CA pretreatment for 30 s resulted in a denser and thicker LDH coating.Increase in the CA pretreatment time significantly led to the improvement in corrosion resistance of the coated AZ80 alloy.The corrosion current density of the coated alloy was lower by three orders of magnitude as compared to the uncoated alloy.展开更多
Global biodiversity loss and mass extinction of species have raised serious global concerns,especially in fragile ecosystems.Karst forest,a well-known fragile ecosystem,is served as a natural laboratory for biogeograp...Global biodiversity loss and mass extinction of species have raised serious global concerns,especially in fragile ecosystems.Karst forest,a well-known fragile ecosystem,is served as a natural laboratory for biogeographical,ecological,evolutionary,and taxonomic research.However,species richness and distribution patterns in karst forests largely remain unclear.Orchidaceae has been regarded as the“flagship”group of plant diversity.In this study,we use Wanfengshan Nature Reserve in southeast Yunnan,China,as a model to determine the conservation status of orchids in the karst forest by conducting systematic field surveys in the past three years from 2019 to 2022.In total,we identified 78 orchid species in 35 genera in Wanfengshan Nature Reserve.The dominant species were Bulbophyllum andersonii,Eria coronaria,Nervilia mackinnonii and Paphiopedilum micranthum.Multiple life forms were also observed,including epiphyte(14.29%),facultative epiphyte(18.18%),lithophyte(23.38%),and terrestrial(44.15%).Orchid species richness showed a bimodal pattern varied with altitude,the higher richness was recorded at 1,500-1,600 and 1,200-1,300 m,while the minimum was below 1,100 m.Each independent hill is rich in orchid species including‘endemic’species.A total of 25(33.8%)orchid species were considered threatened by the Redlist of Chinese Vascular Plants(Qin et al.,2017),including 3 CR species,5 EN species and 17 VU species.We call for more research addressing the mechanisms of ecological adaption,mycorrhizal interactions,and pollination of orchids in karst forests,and effective ways for recovery and conservation of orchids.展开更多
文摘目的 评价iRoot BP Plus用于乳磨牙牙髓切断术的临床疗效。方法 选取因龋坏就诊儿童口腔科的患儿89名,下颌乳磨牙120颗,随机分为两组,分别采用iRoot BP Plus和三氧化矿物凝集体(MTA)作为盖髓剂,行牙髓切断术,术后3、6、12个月复查,通过临床及X线片检查进行疗效评价。结果 iRoot BP Plus和MTA作为盖髓剂,牙髓切断术后1年临床疗效观察,iRoot BP Plus组60例中,失访5例,成功50例,失败5例,成功率90.9%,对照组MTA组60例中,失访5例,成功46例,失败9例,成功率83.6%,两组间无统计学差异(P> 0.05)。结论 iRoot BP Plus用于乳磨牙牙髓切断术取得了良好的临床效果,临床操作简单且不引起牙冠变色,具有良好的应用前景。
文摘目的观察iRoot BP Plus作为盖髓剂,用于小型猪乳前磨牙牙髓切断术后牙髓的组织学变化,探讨i Root BP Plus广泛应用于临床的可行性。方法选用4只5月龄小型猪,选取双侧上下颌乳前磨牙共32颗,行牙髓切断术。随机选择一侧乳前磨牙为实验组,采用iRoot BP Plus作为盖髓剂,另一侧为对照组,采用MTA作为盖髓剂,分别于术后2、4、8、12周处死动物。切取含实验牙的上下颌骨块,进行标本固定和HE染色,观察术后牙髓组织病理学变化。结果i Root BP Plus和MTA均可促进修复性牙本质形成,iRoot BP Plus盖髓后形成修复性牙本质较MTA早,术后8周可见牙本质桥形成,术后12周的牙本质桥形态较规则。二者均未引起浅表牙髓组织坏死,牙本质桥下方的牙髓组织表面在术后4周可见慢性炎症,术后8周炎症基本消失。结论在小型猪乳牙牙髓切断术中,使用iRoot BP Plus盖髓后12周可以形成与MTA盖髓相似的、形态较好的牙本质桥,且牙髓状态良好,为MTA临床良好替代的盖髓剂。
文摘目的分析全身性与腹腔内联合双向化疗在进展期胃癌患者根治术后腹膜复发转移中的应用效果及生存获益情况。方法回顾性选取2018年1月至2020年12月安徽医科大学附属六安医院收治的106例进展期胃癌根治术后腹膜复发转移患者的临床资料,根据化疗方式的不同进行分组,接受腹腔内联合双向化疗的57例患者纳入观察组,接受全身性化疗的49例患者纳入对照组。比较两组患者腹膜癌指数(peritoneal cancer index,PCI)评分、毒副反应、生活质量及生存获益情况。结果化疗后,观察组PCI评分低于对照组,差异有统计学意义(P<0.05);两组患者毒副反应差异无统计学意义(P>0.05);观察组化疗后症状、躯体和情绪功能、整体生活质量和单项测量项目评分均高于对照组(P<0.05);观察组2年生存率(38.60%)高于对照组(18.37%),差异有统计学意义(P<0.05);观察组中位无复发生存时间为15个月,对照组为8个月,差异有统计学意义(P<0.05)。结论相比于全身性化疗,将腹腔内联合双向化疗应用于进展期胃癌患者根治术后腹膜复发转移的治疗中,可提高生存率和生活质量,延长无复发生存时间,未明显增加毒副反应。
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.51601108 and 52071191)the Natural Science Foundation of Shandong Province(ZR2020ME011).
文摘In this study,the effects of intermetallic compounds(Mg_(17)Al_(12)and Al_(8)Mn_(5))on the Mg-Al layered double hydroxide(LDH)formation mechanism and corrosion behavior of an in-situ LDH/Mg(OH)_(2)steam coatings on AZ80 Mg alloy were investigated.Citric acid(CA)was used to activate the alloy surface during the pretreatment process.The alloy was first pretreated with CA and then subjected to a hydrothermal process using ultrapure water to produce Mg-Al-LDH/Mg(OH)_(2)steam coating.The effect of different time of acid pretreatment on the activation of the intermetallic compounds was investigated.The microstructure and elemental composition of the obtained coatings were analyzed using FE-SEM,EDS,XRD and FT-IR.The corrosion resistance of the coated samples was evaluated using different techniques,i.e.,potentiodynamic polarization(PDP),electrochemical impedance spectrum(EIS)and hydrogen evolution test.The results indicated that the CA pretreatment significantly influenced the activity of the alloy surface by exposing the intermetallic compounds.The surface area fraction of Mg_(17)Al_(12)and Al_(8)Mn_(5)phases on the surface of the alloy was significantly higher after the CA pretreatment,and thus promoted the growth of the subsequent Mg-Al-LDH coatings.The CA pretreatment for 30 s resulted in a denser and thicker LDH coating.Increase in the CA pretreatment time significantly led to the improvement in corrosion resistance of the coated AZ80 alloy.The corrosion current density of the coated alloy was lower by three orders of magnitude as compared to the uncoated alloy.
基金supported by Doctoral Program of Yunnan Forestry Technological College(KY(ZD)201905)the Candidates of the Young and Middle Aged Academic Leaders of Yunnan Province[202305AC160024]Shenzhen Key Laboratory for Orchid Conservation and Utilization(OU202201)to Q.Liu.
文摘Global biodiversity loss and mass extinction of species have raised serious global concerns,especially in fragile ecosystems.Karst forest,a well-known fragile ecosystem,is served as a natural laboratory for biogeographical,ecological,evolutionary,and taxonomic research.However,species richness and distribution patterns in karst forests largely remain unclear.Orchidaceae has been regarded as the“flagship”group of plant diversity.In this study,we use Wanfengshan Nature Reserve in southeast Yunnan,China,as a model to determine the conservation status of orchids in the karst forest by conducting systematic field surveys in the past three years from 2019 to 2022.In total,we identified 78 orchid species in 35 genera in Wanfengshan Nature Reserve.The dominant species were Bulbophyllum andersonii,Eria coronaria,Nervilia mackinnonii and Paphiopedilum micranthum.Multiple life forms were also observed,including epiphyte(14.29%),facultative epiphyte(18.18%),lithophyte(23.38%),and terrestrial(44.15%).Orchid species richness showed a bimodal pattern varied with altitude,the higher richness was recorded at 1,500-1,600 and 1,200-1,300 m,while the minimum was below 1,100 m.Each independent hill is rich in orchid species including‘endemic’species.A total of 25(33.8%)orchid species were considered threatened by the Redlist of Chinese Vascular Plants(Qin et al.,2017),including 3 CR species,5 EN species and 17 VU species.We call for more research addressing the mechanisms of ecological adaption,mycorrhizal interactions,and pollination of orchids in karst forests,and effective ways for recovery and conservation of orchids.
