Response of the Ginseng C_(2)H_(2)-Type Zinc Finger Protein Family PgZFPs Gene to Methyl Jasmonate Regulation

The main active components of ginseng are ginsenosides,which play significant roles in treating cardiovascular diseases,cancer,and providing antioxidant effects.Ginsenosides are primarily synthesized through the mevalo-nate pathway and the methylerythritol phosphate pathway.Many key enzyme genes involved in this biosynthetic process have been cloned and validated,yet the regulatory functions of transcription factors remain unclear.The C_(2)H_(2)-type zincfinger protein family,one of the largest families of transcription factors,is crucial in plant growth and development,response to biotic and abiotic stresses,and regulation of secondary metabolism.This study,based on the ginseng transcriptome database from Jilin,conducted a correlation analysis between the expression levels of PgZFPs genes in the Jilin ginseng C_(2)H_(2)-type zincfinger protein family and ginsenoside content,a gen-ome-wide association study of PgZFPs,and co-expression analysis of PgZFPs with validated key enzyme genes.Ultimately,five candidate genes involved in ginsenoside biosynthesis were identified.The involvement of PgZFP27 and PgZFP-59-02 genes from the PgZFPs family in the biosynthesis of ginsenosides was validated through in vitro methyl jasmonate(MeJA)induction experiments.This result provides new genetic resources for the biosynthesis of ginsenosides.

EXISTENCE AND UNIQUENESS OF THE POSITIVE STEADY STATE SOLUTION FOR A LOTKA-VOLTERRA PREDATOR-PREY MODEL WITH A CROWDING TERM

This paper deals with a Lotka-Volterra predator-prey model with a crowding term in the predator equation.We obtain a critical value λ1^D(Ω0),and demonstrate that the existence of the predator inΩ0 only depends on the relationship of the growth rateμof the predator and λ1^D(Ω0),not on the prey.Furthermore,whenμ<λ1^D(Ω0),we obtain the existence and uniqueness of its positive steady state solution,while whenμ≥λ1^D(Ω0),the predator and the prey cannot coexist inΩ0.Our results show that the coexistence of the prey and the predator is sensitive to the size of the crowding regionΩ0,which is different from that of the classical Lotka-Volterra predator-prey model.

Do ESG Scores in Corporations Improve Green Innovation Empirical Evidence from Listed Chinese Companies

The ESG score system is a fundamental component of the green financial system that is essential in promoting corporate environmental progress.In this work we investigate the micro-environmental impact of ESG scores using panel fixed effects models.We examine the processes underlying the influence of ESG scores on the performance of corporate green innovation as well as any potential inequalities in this impact under different moderating factors.To conduct our analysis we use data from Chinese-listed A-shares on the Shanghai and Shenzhen stock exchanges from 2010 to 2019.Our study demonstrates a relationship between corporate green innovation and ESG ratings indicating that higher ESG ratings assist businesses in achieving better green innovation results.This beneficial effect is evident both numerically and qualitatively and it continues to hold up even after being put through several demanding tests.Additionally we pinpoint two main ways that ESG encourages corporate green innovation by boosting government-enterprise ties and strengthening corporate investment efficiency.We also note that while business characteristics aligned with sustainability further enhance the favorable influence of ESG on green innovation performance characteristics linked to ecologically detrimental activities impede the contribution of ESG to green innovation.Our study adds to the body of knowledge already available on corporate environmental performance and green finance by offering empirical insights that can help enhance corporate environmental development and improve the ESG rating system.

Therapeutic robots for post-stroke rehabilitation

Stroke is a prevalent,severe,and disabling healthcare issue on a global scale,inevitably leading to motor and cognitive deficits.It has become one of the most significant challenges in China,resulting in substantial social and economic burdens.In addition to the medication and surgical interventions during the acute phase,rehabilitation treatment plays a crucial role in stroke care.Robotic technology takes distinct advantages over traditional physical therapy,occupational therapy,and speech therapy,and is increasingly gaining popularity in post-stroke rehabilitation.The use of rehabilitation robots not only alleviates the workload of healthcare professionals but also enhances the prognosis for specific stroke patients.This review presents a concise overview of the application of therapeutic robots in poststroke rehabilitation,with particular emphasis on the recovery of motor and cognitive function.

Heat-treated glassy carbon under pressure exhibiting superior hardness,strength and elasticity

Glassy carbon(GC)is a type of non-graphitizing disordered carbon material at ambient pressure and high temperatures,which has been widely used due to its excellent mechanical properties.Here we report the changes in the microstructure and mechanical properties of GC treated at high pressures(up to 5 GPa)and high temperatures.The formation of intermediate sp2-sp3 phases is identified at moderate treatment temperatures before the complete graphitization of GC,by analyzing synchrotron X-ray diffraction,Raman spectra,and transmission electron microscopy images.The intermediate metastable carbon materials exhibit superior mechanical properties with hardness reaching up to 10 GPa and compressive strength reaching as high as 2.5 GPa,nearly doubling those of raw GC,and improving elasticity and thermal stability.The synthesis pressure used in this study can be achieved in the industry on a commercial scale,enabling the scalable synthesis of this type of strong,hard,and elastic carbon materials.

Concomitant transverse myelitis and Guillain-Barré syndrome following varicella-zoster virus infection

To the Editor:Currently known syndromes of acute post-infectious or inflammatory demyelination include acute disseminated encephalomyelitis,encephalitis,transverse myelitis(TM),and Guillain–Barrésyndrome(GBS).Demyelination is frequently limited to the central or peripheral nervous systems.The coexistence of myelitis and demyelinating peripheral neuropathy has only been reported in a few children[1,2]and young adults.[3]Also,concomitant TM and GBS in elderly immunocompetent patients has been rarely described.