The Relationship Between Social Isolation, Psychological Resilience, and Psychological Well- Being Among Older People in the Community

Objective:To explore the relationship between social isolation,psychological resilience,and psychological well-being in community-dwelling older adults.Methods:A questionnaire survey was conducted with 265 community-dwelling older adults using the Social Isolation Scale for the Elderly(C-SIS),the 10-item Brief Psychological Resilience Scale,and the Comprehensive Happiness Questionnaire(MHQ).The results were statistically analyzed using SPSS 27.0.Results:The highest score on the Social Isolation Scale for Community Elderly was 23,with a mean entry score of 2.36±0.62.A score of 14 was the cut-off point,with scores of≤14 classified as social isolation.There were 136 cases with scores below 14,resulting in a social isolation incidence rate of 51.3%.The median(P50)psychological resilience score was 27,indicating a higher level of resilience.The total score on the Psychological Well-being Scale was 161,suggesting a moderate to slightly higher level of well-being.Social isolation had a direct negative effect on psychological well-being,while psychological resilience had a positive effect.Conclusion:Older adults should be supported in reducing the incidence of social isolation and increasing psychological resilience to enhance psychological well-being and promote successful aging.

新时代背景下分析化学微课的构建——以滴定突跃为例

伴随着信息化技术的发展及不可抗力因素的影响等,传统的课堂教学模式已不能满足分析化学的现代化教学。微课是一种新兴的、依托于互联网的优良数字化教学资源。本文以分析化学滴定分析中的滴定突跃为主题,阐述了微课的设计、构思、内容和形式等,展示了微课在分析化学教学中的应用,为传统教学提供了新思路。

Crossed intergrowth triggered TS-2 microsphere:Formation mechanism,modification and catalytic performance

TS-2 microspheres,consisting of intergrown primary nanocrystals,was prepared by controlling the synthetic parameters.The effects of the amount of quaternary ammonium cations as structure-directing agent,H2O/Si ratio,the presence of alcohol and the temperature were carefully investigated on the crystallization process.The high alkalinity was proved to be highly important for the preservation of the microsphere morphology initially formed,due to the unique intergrown stacking style.An alkali treatment with the aqueous solution of structure-directing agent,organic amine and ammonium salt and subsequent Na+ion-exchange were performed to enhance the catalytic activity of TS-2 microsphere in the cyclohexanone ammoximation reactions,with both the conversion and selectivity higher than 99%.In the continuous reaction,the TS-2 microspheres exhibited to be durable catalyst with potential application in industrial ammoximation processes.

Surface defect-rich ceria quantum dots anchored on sulfur-doped carbon nitride nanotubes with enhanced charge separation for solar hydrogen production

Designing defect-engineered semiconductor heterojunctions can effectively promote the charge carrier separation.Herein,novel ceria(CeO2) quantum dots(QDs) decorated sulfur-doped carbon nitride nanotubes(SCN NTs) were synthesized via a thermal polycondensation coupled in situ depositionprecipitation method without use of template or surfactant.The structure and morphology studies indicate that ultrafine CeO2 QDs are well distributed inside and outside of SCN NTs offering highly dispersed active sites and a large contact interface between two components.This leads to the promoted formation of rich Ce^(3+) ion and oxygen vacancies as confirmed by XPS.The photocatalytic performance can be facilely modulated by the content of CeO2 QDs introduced in SCN matrix while bare CeO2 does not show activity of hydrogen production.The optimal catalyst with 10% of CeO2 loading yields a hydrogen evolution rate of 2923.8 μmol h-1 g-1 under visible light,remarkably higher than that of bare SCN and their physical mixtures.Further studies reveal that the abundant surface defects and the created 0 D/1 D junctions play a critical role in improving the separation and transfer of charge carriers,leading to superior solar hydrogen production and good stability.

Classification of facial nerve aberration in congenital malformation of middle ear:Implications for surgery of hearing restoration

Objectives: Facial nerve aberration is the most troublesome situation in congenital malformations of middle ear.The aim of our study is to investigate its imaging and clinical features as well as relevant choice of surgical techniques for hearing improvement.Methods: A retrospective study involving review of clinical data of 227 patients(256 ears) with congenital middle ear anomaly was undertaken, including preoperative computed tomography(CT) data, surgical records and videos.Results: Aberration involving intratemporal facial nerve was found in 82/256 ears(32.03%) with congenital middle ear anomaly. The most common forms of aberration included overhanging over the oval window(50/82 ears, 60.98%), bifurcation(3/82 ears, 3.66%) and transverse over the promontory(3/82 ears, 3.66%), counting for 68.29%(56/82) of the cases with facial nerve aberration. Concomitant stapes malformation was found in 76/82 ears(92.68%) and atresia or stenosis of the oval window in 27/82 ears(32.93%). In 9/82 ears(10.98%) both stapes and oval window was absent. Elective surgeries for the purpose of hearing improvement included stapodotomy + piston implantation, labyrinthotomy, labyrinthotomy + total ossicular replacement prosthesis(TORP) implantation and Vibrant Soundbridge(VSB) implantation.Conclusion: The majority of facial nerve aberration in congenital malformation of middle ear involves displacement of facial nerve, in addition to concomitant malformations of the stapes and/or oval window, which may influence the choice of surgery for hearing improvement. VSB implantation may be considered as a useful option.

Development of in-situ Micro-Raman spectroscopy system for autoclave experimental apparatus

We developed a set of in-situ Micro-Raman spectroscopy system for autoclave experimental apparatus because of the scientific significance of in-situ Micro-Raman spectroscopy system under the high-pressure hydrothermal condition.We used this system to measure the Raman spectrum of water-fluid and quartz crystal at the temperature ranging from 125 to 420℃.The signal-tonoise ratio of the Raman signal is good.

The lectin gene TRpL1 of tetraploid Robinia pseudoacacia L.response to salt stress

Lectins are natural proteins in animals,plants,and microorganisms and can be divided into 12 families.These lectins play important roles in various environmental stresses.Some polyploid plants show tolerance to environmental stresses and to insect pests.However,the mechanism of stress tolerance is unclear.Tetraploid Robinia pseudoacacia(4×)under salt stress showed higher tolerance than diploid R.pseudoacacia(2×).As lectin can improve stress tolerance,it was questioned whether the stress resistance of polyploid plants was related to the lectin protein.In this study,salt resistance of lectin gene TRpL1 was verified by its over-expression in plants.In addition,salt resistance of lectin protein by E.coli strains was detected.The data revealed that the over-expression transgenic plants of TRpL1 showed better salt tolerance than control plants under salt stress,and the TRpL1-expressing strain also grew better in the medium with added NaCl.Therefore,tetraploid plants can resist salt stress through TRpL1 protein regulation.

ComGIS-Based Early Warning System of Rural Drinking Water Safety in Ya’an City of Sichuan, China

According to characteristic index of spatial-temporal variability of rural drinking water safety in Ya’an City of Sichuan, China, such as water quantity, water quality, convenience degree and guaranteed rate, etc., this study elaborated the basic framework, model’s methodology structure in early warning system of rural drinking water safety on the basis of ComGIS and initially designed information collection, search and re-trieval, evaluation and analysis of factors, dynamic prediction and dynamic early-warning and functions of guidance and management in this system. The design of this system provided scientific basis to grasp the state of rural drinking water safety timely, release early warning information and properly take necessary control measures, etc. The evaluation results showed that the overall trend was getting better. It proved that the rising pressure value and response value were main reasons which caused the rising evaluation value of rural drinking water safety.

An experimental study of interaction between pure water and alkaline feldspar at high temperatures and pressures

Due to the important scientific significance of the interaction between alkaline feldspar and high-temperature and high-pressure fluids. We have conducted a series of autoclave experiments of feldspar dissolution and secondary mineral precipitation in conditions of 250–500℃, 8-50 MPa, and pH = 3.0 and 5.5. Based on the interaction experiments between alkaline feldspar and fluid of high-temperatures and high-pressures, we get the main results as follows:(1) The law that people have grasped below the critical point about the influence of temperature, pressure, and pH value on the alkaline feldspar dissolution behavior is still held above the critical point.(2) Due to the experimental techniques of autoclave flip 180°—sharp quenching and based on electron microprobe analysis of mineral new formed, theoretical analysis has determined that the new altered minerals distributed on the island dissolution surface of feldspar are products of precipitation on a feldspar surface after saturation of the relative ion concentration in water fluid.

AP-2α gene transfection effects cell proliferation and cell apoptosis of SW620 cells line in colorectal carcinoma

Objective:We investigated the effects of exogenous AP-2α gene on SW620 cell cycle, apoptosis and proliferation. Methods:The Plasmid pcDNA3.1(+)-AP-2α was transfected into colorectal carcinoma SW620 cells line by liposome mediation for transient expression. After AP-2α transfected SW620 cells, the exogenous AP-2α mRNA and protein express were determined by the method of Real-time PCR and Western blot. In order to elucidate the effect of expression of exogenous AP-2α gene on the colorectal cancer cell SW620, the proliferation rates were analyzed by growth curves for cells including SW620, pcDNA3.1(+)/SW620 and pcDNA3.1(+)-AP-2α/SW620. At same time, the apoptotic rate of cells and the cell cycle analysis were also tested by flow cytometry. Results: The mRNA and protein expressions of AP-2α gene could be enhanced by transfecting of pcDNA3.1(+)-AP-2α recombinant plasmid into SW620 cell. The cell growth rates of SW620 cells transfected with pcDNA3.1(+)/AP-2α were slower than those transfected with pcDNA3.1(+) or untransfected. The apoptotic rates were increased compared with pcDNA3.1(+)/SW620 and SW620 (P<0.05), which indicated that over-expression of AP-2α gene could efficiently inhibit the growth of SW620 cells and induce apoptosis. FCM analyses indicated that the cells being arrested in G1 phase. Conclusion: AP-2α gene can be efficiently transfected into SW620 cells and over-expression AP-2α protein in the transfected cells. AP-2α induces G1 arrest and apoptosis, suppressive effect on cell growth.

Isolating QTL controlling sugarcane leaf blight resistance using a two-way pseudo-testcross strategy

Sugarcane leaf blight(SLB),caused by Stagonospora tainanensis,is one of the most harmful fungal diseases,threatening the sugarcane industry and causing high losses of cane yield and sugar in susceptible cultivars.Using a two-way pseudo-testcross mapping strategy in combination with array genotyping,two high-density genetic maps were constructed for sugarcane cultivars YT93-159 and ROC22 with mean densities of respectively 3.0 and 3.5 cM per marker,and covering respectively 4485 and 2720 cM of genetic distance.The maps showed highly conserved colinearity with the genome of the ancestral species Saccharum officinarum,supporting the reliability of the linkage configurations of the maps.Quantitative trait loci(QTL)analysis of SLB resistance revealed six QTL(qSLB-1–qSLB-6).The major QTL qSLB-1 explaining 16.4%of phenotypic variance was assigned as the main QTL,and the total percentages of phenotypic variance explained in YT93-159 and ROC22 were 37.9%and 17.6%,respectively.Nine transcription factor and seven pathogen receptor genes lying in the qSLB-1 interval were highly expressed and are proposed as candidate causal genes for SLB resistance.

The progression of microRNA in human colorectal cancer

MicroRNAs (miRNAs) constitute a class of small non-coding RNAs that function as posttranscriptional gene regulators. The dysregulation of miRNAs has been linked to a series of diseases, including various types of cancer. Since their discovery in the miRNAs of cancer patients, there has been a steady increase in the study of miRNAs as stable, noninvasive biomarkers. Although several challenges remain to be concerned, miRNAs could be useful, non-invasive biomarkers for colorectal cancer diagnostics and prognosis. In this review, we summarized the discovery of miRNAs and their potential as biomarkers. We discussed their possible structural, function and further emphasized the significance of miRNAs in colorectal cancer (CRC).

Zno Nanowires Network Synthesis and Its Applications on Transfer-Free UV Photodetector

Horizontally ZnO nanowires and 3D nanowires network were synthesized on dielectric silicon substrate and SiO_2 insulate substrate by catalyst-free CVD(chemical vapor deposition)method.Both the micro structure and the roughness of the substrate surface by the photoetching method and RIE ethingmethod play a significant role on the horizontally ZnO nanowires network growth when the

章程自治视角下的管理层权力下沉与企业创新

公司的章程自治作为宏观制度的外规内化,是一种体现公司自主意识的制度创新,而内部制度设计下的治理主体权力配置能否体现在公司的创新投资上仍须进一步检验。本文以手工收集的2010—2019年上市公司的章程修改数据为基础,将章程中自主增加管理层权力的公司作为处理组,将从未发生管理层权力变动的公司作为对照组,采用双重差分法和倾向得分匹配法,实证检验管理层权力下沉与企业创新的关系。研究发现:(1)公司在通过自主修改章程进而将权力下沉至管理层之后,其研发创新投入显著增加;(2)进一步的分析表明,在获得授权之后,管理层会积极开展基础性研究,推动实质性创新;(3)调节效应分析表明,运营效率和管理层影响力等内部因素以及制度环境和产业特征等外部因素,都会对管理层权力下沉与创新投入的正向关系产生显著的调节作用,而产权性质对上述关系的影响并不显著。本文的研究结果表明,公司基于章程自治进行管理层权力下沉安排将强有力地激励管理层进行研发投资,提高公司创新水平,即通过内部制度创新合理优化管理层权力配置将有利于公司的发展。

Tuning interaction strength between CeO_(2) and iridium to promote CO oxidation over Ir/TiO_(2)

The interaction between support and noble metal plays a crucial role in heterogeneous catalysis design.However,how to tune metal support interactions to optimize the activity still needs further exploration.CeO_(2) was introduced to promote CO oxidation ove r Ir/TiO_(2) by adjusting the interaction strength between iridium(Ir)and CeO_(2).The strong interaction between Ir and CeO_(2) blocks CO adsorption and causes low CO oxidation activity.However,introducing CeO_(2) on Ir/TiO_(2) produces localized interaction between Ir and CeO_(2),which can tune the surface electronic state of Ir,so a"volcano curve"relationship between CO oxidation activity and electronic state is built.Limited amount of CeO_(2) on Ir/TiO_(2)(Ir/Ce_(0.2)Ti)leads to CO complete oxidization at 22℃,and a new pathway for CO oxidation was explored.The study demonstrates that the utilization of tuning interaction strength between active metal and support is a potential method to increase the catalytic activity.

Light-up the white light emission in microscale with a superior deep-blue AIE fiber as wave-guiding source

The development of high-performance organic blue light-emitting emitters is in urgent to act as an excitation source to contribute the white light generation.On the other hand,the investigation on optical waveguides have been received increasing attentions because they can manipulate the light propagation accurately in the microscale to boost the optoelectronic and energy conversion applications.In this work,we facilely prepared a deep-blue aggregation-induced emission(AIE)dye,namely TPP-4OMe,which shows high luminescent efficiency,narrow emission band and good stability in the aggregate state.TPP-4OMe can be fabricated as deep-blue AIE microfibers readily with definite morphology and composition.Based on the AIE microfibers,the active waveguide to transmit deep-blue emission signals can be achieved with a very low optical loss coefficient(α)of 6.7×10^(−3)dBμm^(−1).Meanwhile,the full-visible broadband low-loss passive waveguide can be well performed with these AIE microfibers,which has never been observed in the pure organic crystals.More interestingly,the excellent properties of AIE microfibers enable them to act as a wave-guiding excitation source,resulting in a distinct and pure white light emission.The present work not only provides excellent blue light-emitting materials but also bridges the waveguide to realize the efficient white light emission to accelerate the practical applications.

Coping strategy of independent directors for job-fulfillment risk under different ownership types and enforced legal environments

Ownership type,legal system evolution and their interaction significantly affect the incentives and behaviors of independent directors.We use the 2019 Securities Law revision as an exogenous shock to examine how state-owned enterprises(SOEs)versus non-SOEs and their independent directors respond to variations in regulatory compliance risk.Following the revision,SOEs are more likely to purchase directors’and officers’liability insurance to provide job security for independent directors.Non-SOEs are more likely to compensate for independent directors’fulfillment risk by increasing salaries and their independent directors are more likely to resign to avoid litigation risk.The coping strategies for SOEs,non-SOEs and independent directors are dynamic under different compliance risk stages and are affected by firm-level and director-level characteristics.

异质性环境规制与企业盈余信息质量

层出不穷的环境污染事件加剧了生态环境质量改善压力,导致环境规制持续升级。异质性环境规制如何影响微观企业盈余信息质量?文章以沪深两市A股重污染上市公司为研究样本,实证检验异质性环境规制对企业盈余信息质量的影响。研究发现,显性环境规制对企业盈余信息质量具有抑制作用,其机制在于融资约束、环保投资和媒体关注。隐性环境规制对企业盈余信息质量具有促进作用,其机制在于融资约束和媒体关注。异质性检验发现,上述抑制作用在低产品市场竞争和公司风险较高的情况下更显著,上述促进作用在高产品市场竞争和公司风险较低的情况下更显著。进一步检验发现,环境补贴和公众参与是影响企业盈余信息质量的主要环境规制。考虑盈余调整方向的检验结果显示,显性环境规制对企业盈余信息质量的抑制作用在向上盈余调整的情况下越显著。2013年“大气十条”政策实施后,企业显著调高了可操纵应计利润。

上市公司违规、关系文化与银行信贷风险控制--基于证监会处罚公告前后的跨期考察

本文研究上市公司违规过程中银行信贷风险控制的动态演变过程,并结合关系文化探讨正式制度和非正式制度在此过程中的相互作用关系。按照公司违规发生、违规处罚公告两个时间节点,本文将整个违规过程划分为违规之前、违规期间和违规监管后三个阶段,以2003—2015年A股上市公司为研究样本,考察上市公司违规过程中的借款条件变化情况,以此探讨银行是否能够获取以及如何利用私有信息和公开信息进行信贷风险控制。研究结果表明:银行具有一定的获取私有信息的能力,在上市公司违规行为被监管公告前就已经提高借款利率,并通过缩短借款期限及提高短期借款担保要求等非价格措施进行信贷风险控制;当违规行为被监管后,银行会继续实施这些严格的非价格风险控制措施。进一步研究发现,关系文化弱化了银行在公司违规期间的信贷风险控制效率:在公司违规期间,公司所处地区的关系文化程度越高,债务契约越宽松;而当公司违规行为被监管后,关系文化的影响不再显著;而且,关系文化的作用因公司产权性质的不同而具有较强的异质性;同时,违规行为越严重,银行所采用的债务契约越严苛。本文比较系统地从债权人视角研究了证券市场监管的经济后果,为我们更好地理解银行的信贷风险管理行为提供了经验证据支持。

Terson综合征玻璃体切割术后黄斑裂孔1例

患者,女,42岁,因"双眼视物模糊18 d"于2021年7月至嘉兴市眼科医院就诊。患者20 d前在西藏旅游过程中与人争吵后突发剧烈头痛、昏迷,外院诊断"颅内动脉瘤破裂致蛛网膜下腔出血",并行"颅内动脉瘤介入栓塞术",苏醒后即感双眼视物模糊,自述此前双眼视力正常。既往身体健康,否认系统病史及家族遗传病史。眼部检查:双眼视力手动,双眼视力矫正后不提高;双眼眼压均为14 mmHg(1 mmHg=0.133 kPa)。双眼眼前节未见异常,玻璃体血性混浊,眼底失窥。眼部B型超声检查示双眼玻璃体细点状弱回声,聚集成片。结合颅内动脉瘤破裂病史,诊断:双眼玻璃体积血,Terson综合征,颅内动脉瘤介入栓塞术后。