抽水蓄能和新型储能是实现碳达峰碳中和,支撑以新能源为主体新型电力系统的重要技术和基础装备。压缩空气储能(compressed air energy storage, CAES)是一种利用压缩空气作为介质来储存能量和发电的技术,是目前除抽水蓄能以外规模最大...抽水蓄能和新型储能是实现碳达峰碳中和,支撑以新能源为主体新型电力系统的重要技术和基础装备。压缩空气储能(compressed air energy storage, CAES)是一种利用压缩空气作为介质来储存能量和发电的技术,是目前除抽水蓄能以外规模最大的物理储能方式,而硬岩浅埋型人工储气洞库选址灵活,具有规模化、商业化的发展潜力。面对我国大中型压缩空气储能电站开发建设形势和要求,结合国内外相关研究和工程实践经验,本文提出了硬岩条件下浅埋人工储气洞库整体稳定、局部稳定、循环稳定和密封层稳定的工程设计基本理念,总结提炼了洞库选址及地质勘探要求、埋深设计、储气库布置、结构设计、密封系统设计等方法,为压缩空气储能电站浅埋人工储气洞库设计提供借鉴和参考。展开更多
Background Several small sample-size observational studies evaluated the association of plasma brain natriuretic peptide （BNP） or N-terminal pro-brain natriuretic peptide （NT-proBNP） with atrial fibrillation （AF...Background Several small sample-size observational studies evaluated the association of plasma brain natriuretic peptide （BNP） or N-terminal pro-brain natriuretic peptide （NT-proBNP） with atrial fibrillation （AF）,but the results were contradictory.We aimed to perform a meta-analysis of relevant studies to evaluate the availability of this association.Methods We performed an extensive literature search on PubMed,Web of Science （WOS） and the Cochrane Library databases.Pooled standardized mean difference （SMD） and 95% confidence interval （CI） were calculated to assess the strength of association using random effects models.We performed sensitivity and subgroup analyses to explore the potential sources of heterogeneity.We also estimated publication biases.Statistical analyses were performed using the STATA 12.0 software.Results A total of 11 studies including 777 cases and 870 controls were finally analyzed.Overall,the brain natriuretic peptide/N-terminal pro-brain natriuretic peptide levels were higher in atrial fibrillation patients than controls without atrial fibrillation.Results showed that the SMD in the natriuretic peptide levels between cases and controls was 2.68 units （95%CI 1.76 to 3.60）; test for overall effect z-score=5.7 （P 〈0.001）.There was significant heterogeneity between individual studies （I2=97.8%; P 〈0.001）.Further analysis revealed that differences in the assay of natriuretic peptide possibly account for this heterogeneity.Conclusions Increased BNP/NT-proBNP levels were associated with the presence of atrial fibrillation.This finding indicates that BNP/NT-proBNP may prove to be a biomarker of an underlying predisposition to AF.展开更多
文摘抽水蓄能和新型储能是实现碳达峰碳中和,支撑以新能源为主体新型电力系统的重要技术和基础装备。压缩空气储能(compressed air energy storage, CAES)是一种利用压缩空气作为介质来储存能量和发电的技术,是目前除抽水蓄能以外规模最大的物理储能方式,而硬岩浅埋型人工储气洞库选址灵活,具有规模化、商业化的发展潜力。面对我国大中型压缩空气储能电站开发建设形势和要求,结合国内外相关研究和工程实践经验,本文提出了硬岩条件下浅埋人工储气洞库整体稳定、局部稳定、循环稳定和密封层稳定的工程设计基本理念,总结提炼了洞库选址及地质勘探要求、埋深设计、储气库布置、结构设计、密封系统设计等方法,为压缩空气储能电站浅埋人工储气洞库设计提供借鉴和参考。
文摘Background Several small sample-size observational studies evaluated the association of plasma brain natriuretic peptide （BNP） or N-terminal pro-brain natriuretic peptide （NT-proBNP） with atrial fibrillation （AF）,but the results were contradictory.We aimed to perform a meta-analysis of relevant studies to evaluate the availability of this association.Methods We performed an extensive literature search on PubMed,Web of Science （WOS） and the Cochrane Library databases.Pooled standardized mean difference （SMD） and 95% confidence interval （CI） were calculated to assess the strength of association using random effects models.We performed sensitivity and subgroup analyses to explore the potential sources of heterogeneity.We also estimated publication biases.Statistical analyses were performed using the STATA 12.0 software.Results A total of 11 studies including 777 cases and 870 controls were finally analyzed.Overall,the brain natriuretic peptide/N-terminal pro-brain natriuretic peptide levels were higher in atrial fibrillation patients than controls without atrial fibrillation.Results showed that the SMD in the natriuretic peptide levels between cases and controls was 2.68 units （95%CI 1.76 to 3.60）; test for overall effect z-score=5.7 （P 〈0.001）.There was significant heterogeneity between individual studies （I2=97.8%; P 〈0.001）.Further analysis revealed that differences in the assay of natriuretic peptide possibly account for this heterogeneity.Conclusions Increased BNP/NT-proBNP levels were associated with the presence of atrial fibrillation.This finding indicates that BNP/NT-proBNP may prove to be a biomarker of an underlying predisposition to AF.
