目的探讨阿托伐他汀对高血压脑出血(hypertensive intracerebral hemorrhage,HCH)患者白介素-33(IL-33)水平的影响。方法80例HCH患者随机平分为对照组、观察组,对照组用常规方法治疗,观察组用常规方法联合口服阿托伐他汀治疗。疗程结束...目的探讨阿托伐他汀对高血压脑出血(hypertensive intracerebral hemorrhage,HCH)患者白介素-33(IL-33)水平的影响。方法80例HCH患者随机平分为对照组、观察组,对照组用常规方法治疗,观察组用常规方法联合口服阿托伐他汀治疗。疗程结束时对比两组总有效率、脑水肿绝对体积和相对体积、美国国立卫生院卒中量表(national institutes of health stroke scale,NIHSS)、格拉斯哥昏迷指数(glasgow coma index,GCS)评分,神经元特异性烯醇化酶(neuron specific enolase,NSE)、中枢神经特异蛋白(central nervous system specific protein,S100β)、白介素-33(interleukin-33,IL-33)、白介素-1β(interleukin-1β,IL-1β)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)和C反应蛋白(C-reactive protein,CRP)水平。结果治疗后,观察组总有效率95%高于对照组78%(χ^(2)=5.168,P<0.05)。治疗前两组脑水肿的绝对、相对体积接近,对比差异无统计学意义(t=0.181、0.797,P>0.05);治疗后两组脑水肿的绝对、相对体积均低于治疗前(t=15.323、15.034、24.425、13.038,P<0.05),治疗后观察组脑水肿的绝对、相对体积均少于对照组(t=3.171、13.265,P<0.05)。治疗前两组NIHSS、GCS评分对比差异无统计学意义(t=0.778、0.967,P>0.05);治疗后两组NIHSS评分低于治疗前,GCS评分高于治疗前(t=27.370、23.857、7.101、4.443,P<0.05);治疗后观察组NIHSS评分少于对照组,GCS评分高于对照组(t=7.247、2.713,P<0.05)。治疗前两组NSE、S100β水平对比无统计学差异(t=0.425、0.349,P>0.05);治疗后两组NSE、S100β水平低于治疗前(t=6.065、4.436、20.109、7.030,P<0.05);治疗后观察组NSE、S100β水平少于对照组(t=2.278、12.818,P<0.05)。治疗前两组IL-33、IL-1β、TNF-α和CRP水平对比无统计学差异(t=0.043、1.265、0.708、0.157,P>0.05);治疗后两组IL-33、IL-1β、TNF-α和CRP水平低于治疗前(t=5.120、2.119、11.610、4.207、8.378、3.604、7.552、5.420,P<0.05);治疗后观察组IL-33、IL-1β、TNF-α和CRP水平少于对照组(t=3.703、3.336、2.389、5.087,P<0.05)。两组不良反应发生率对比,差异无统计学意义(χ^(2)=0.312,P>0.05)。结论阿托伐他汀治疗HCH患者疗效显著,显著促进水肿的吸收,减缓功能缺损,缓解意识障碍,降低NSE、S100β炎症因子水平,提高IL-33水平。展开更多
目的探索神经内镜辅助丘脑血肿清除术联合同侧脑室外引流术与丘脑血肿引流联合对侧脑室外引流术治疗丘脑出血破入脑室(thalamic hemorrhage rupture into the ventricle,THRIV)的临床效果。方法选择锦州医科大学附属第一医院2020年9月至...目的探索神经内镜辅助丘脑血肿清除术联合同侧脑室外引流术与丘脑血肿引流联合对侧脑室外引流术治疗丘脑出血破入脑室(thalamic hemorrhage rupture into the ventricle,THRIV)的临床效果。方法选择锦州医科大学附属第一医院2020年9月至2022年6月的丘脑出血破入脑室患者73例,依不同手术治疗方式分为观察组(38例,行神经内镜辅助丘脑血肿清除术联合同侧脑室外引流术治疗)与对照组(35例,行丘脑血肿引流联合对侧脑室外引流术治疗),比较两组患者术后第3天血肿清除率、手术时长及术中的出血量、住院时长及费用、术后并发症及脑水肿情况、术后1 w格拉斯哥昏迷量表(glasgow coma scale,GCS)评分及术后3个月格拉斯哥预后量表(glasgow prognosis scale,GOS)评分。结果两组患者术前的各项指标差异无统计学意义(P>0.05)。观察组手术时长、术中出血量、住院花费和术后第3天血肿清除率均大于对照组,但其住院时间较对照组短,均有统计学意义(P<0.05)。观察组术后脑积水、颅内感染、肺部感染几率较对照组低(P<0.05);两组患者在再出血、癫痫、术后死亡和消化道出血方面差异无统计学意义(P>0.05)。观察组患者术后第3天脑水肿CT评分(BECTS)明显较对照组高,但其术后1 w BECTS较对照组低,差异均存在统计学意义(P<0.05)。观察组患者术后1 w GCS及术后3个月GOS评分均大大超过对照组(P<0.05)。结论神经内镜辅助丘脑血肿清除术联合同侧脑室外引流术可提高患者的血肿清除率,缩减住院时间和术后脑水肿的持续时间。减少术后脑积水、颅内感染和肺部感染的发生率,改善患者的3个月预后。展开更多
Low Earth orbit(LEO) satellite systems provide terrestrial users with services that are not limited by geographical location. However, the conflict between existing allocation schemes and the business variability betw...Low Earth orbit(LEO) satellite systems provide terrestrial users with services that are not limited by geographical location. However, the conflict between existing allocation schemes and the business variability between beams is becoming increasingly prominent. Beam hopping technology allows for a more flexible and versatile approach to satellite resource allocation. This paper proposes a beam hopping pattern optimization scheme that jointly considers the interference threshold distance and beam service priority, reducing the inter-beam co-channel interference(CCI). In the cluster area, a non-orthogonal multiple access(NOMA)-based collaborative beam hopping(NCBH) scheme is proposed to minimize the cell-edge user(CEU) interference. Since there is a difference in channel gain between the CEU and cellcenter user(CCU), this scheme forms a NOMA cluster to perform power domain multiplexing and formulates a NOMA cluster pairing strategy according to the user location to reduce the CCI of the CEU. After NOMA cluster pairing, the optimal carrier frequency of the NOMA cluster is selected by a reinforcement learning algorithm. The simulation results verify the excellent performance of the proposed NCBH scheme regarding the user’s received power, transmission rate, and outage probability.展开更多
MARCH 9,2023 marks the 50th anniversary of the establishment of diplomatic relations between China and Spain.To gain more insight into the development of this relationship,China Today recently spoke to Wu Haitao,Chine...MARCH 9,2023 marks the 50th anniversary of the establishment of diplomatic relations between China and Spain.To gain more insight into the development of this relationship,China Today recently spoke to Wu Haitao,Chinese ambassador to Spain.According to Wu,the two sides have planned a series of celebrations for the occasion.展开更多
The proliferation of the global datasphere has forced cloud storage systems to evolve more complex architectures for different applications.The emergence of these application session requests and system daemon service...The proliferation of the global datasphere has forced cloud storage systems to evolve more complex architectures for different applications.The emergence of these application session requests and system daemon services has created large persistent flows with diverse performance requirements that need to coexist with other types of traffic.Current routing methods such as equal-cost multipath(ECMP)and Hedera do not take into consideration specific traffic characteristics nor performance requirements,which make these methods difficult to meet the quality of service(QoS)for high-priority flows.In this paper,we tailored the best routing for different kinds of cloud storage flows as an integer programming problem and utilized grey relational analysis(GRA)to solve this optimization problem.The resulting method is a GRAbased service-aware flow scheduling(GRSA)framework that considers requested flow types and network status to select appropriate routing paths for flows in cloud storage datacenter networks.The results from experiments carried out on a real traffic trace show that the proposed GRSA method can better balance traffic loads,conserve table space and reduce the average transmission delay for high-priority flows compared to ECMP and Hedera.展开更多
文摘目的探讨阿托伐他汀对高血压脑出血(hypertensive intracerebral hemorrhage,HCH)患者白介素-33(IL-33)水平的影响。方法80例HCH患者随机平分为对照组、观察组,对照组用常规方法治疗,观察组用常规方法联合口服阿托伐他汀治疗。疗程结束时对比两组总有效率、脑水肿绝对体积和相对体积、美国国立卫生院卒中量表(national institutes of health stroke scale,NIHSS)、格拉斯哥昏迷指数(glasgow coma index,GCS)评分,神经元特异性烯醇化酶(neuron specific enolase,NSE)、中枢神经特异蛋白(central nervous system specific protein,S100β)、白介素-33(interleukin-33,IL-33)、白介素-1β(interleukin-1β,IL-1β)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)和C反应蛋白(C-reactive protein,CRP)水平。结果治疗后,观察组总有效率95%高于对照组78%(χ^(2)=5.168,P<0.05)。治疗前两组脑水肿的绝对、相对体积接近,对比差异无统计学意义(t=0.181、0.797,P>0.05);治疗后两组脑水肿的绝对、相对体积均低于治疗前(t=15.323、15.034、24.425、13.038,P<0.05),治疗后观察组脑水肿的绝对、相对体积均少于对照组(t=3.171、13.265,P<0.05)。治疗前两组NIHSS、GCS评分对比差异无统计学意义(t=0.778、0.967,P>0.05);治疗后两组NIHSS评分低于治疗前,GCS评分高于治疗前(t=27.370、23.857、7.101、4.443,P<0.05);治疗后观察组NIHSS评分少于对照组,GCS评分高于对照组(t=7.247、2.713,P<0.05)。治疗前两组NSE、S100β水平对比无统计学差异(t=0.425、0.349,P>0.05);治疗后两组NSE、S100β水平低于治疗前(t=6.065、4.436、20.109、7.030,P<0.05);治疗后观察组NSE、S100β水平少于对照组(t=2.278、12.818,P<0.05)。治疗前两组IL-33、IL-1β、TNF-α和CRP水平对比无统计学差异(t=0.043、1.265、0.708、0.157,P>0.05);治疗后两组IL-33、IL-1β、TNF-α和CRP水平低于治疗前(t=5.120、2.119、11.610、4.207、8.378、3.604、7.552、5.420,P<0.05);治疗后观察组IL-33、IL-1β、TNF-α和CRP水平少于对照组(t=3.703、3.336、2.389、5.087,P<0.05)。两组不良反应发生率对比,差异无统计学意义(χ^(2)=0.312,P>0.05)。结论阿托伐他汀治疗HCH患者疗效显著,显著促进水肿的吸收,减缓功能缺损,缓解意识障碍,降低NSE、S100β炎症因子水平,提高IL-33水平。
文摘目的探索神经内镜辅助丘脑血肿清除术联合同侧脑室外引流术与丘脑血肿引流联合对侧脑室外引流术治疗丘脑出血破入脑室(thalamic hemorrhage rupture into the ventricle,THRIV)的临床效果。方法选择锦州医科大学附属第一医院2020年9月至2022年6月的丘脑出血破入脑室患者73例,依不同手术治疗方式分为观察组(38例,行神经内镜辅助丘脑血肿清除术联合同侧脑室外引流术治疗)与对照组(35例,行丘脑血肿引流联合对侧脑室外引流术治疗),比较两组患者术后第3天血肿清除率、手术时长及术中的出血量、住院时长及费用、术后并发症及脑水肿情况、术后1 w格拉斯哥昏迷量表(glasgow coma scale,GCS)评分及术后3个月格拉斯哥预后量表(glasgow prognosis scale,GOS)评分。结果两组患者术前的各项指标差异无统计学意义(P>0.05)。观察组手术时长、术中出血量、住院花费和术后第3天血肿清除率均大于对照组,但其住院时间较对照组短,均有统计学意义(P<0.05)。观察组术后脑积水、颅内感染、肺部感染几率较对照组低(P<0.05);两组患者在再出血、癫痫、术后死亡和消化道出血方面差异无统计学意义(P>0.05)。观察组患者术后第3天脑水肿CT评分(BECTS)明显较对照组高,但其术后1 w BECTS较对照组低,差异均存在统计学意义(P<0.05)。观察组患者术后1 w GCS及术后3个月GOS评分均大大超过对照组(P<0.05)。结论神经内镜辅助丘脑血肿清除术联合同侧脑室外引流术可提高患者的血肿清除率,缩减住院时间和术后脑水肿的持续时间。减少术后脑积水、颅内感染和肺部感染的发生率,改善患者的3个月预后。
基金supported by the Special Program of Guangxi Science and Technology Base and Talents under Grant No.AD18281020 and Grant No.AD18281044National Natural Science Foundation of China under Grant No.Nos.62161006 and Grant No.Nos.61662018+1 种基金Dean Project of Key Laboratory of Cognitive Radio and Information Processing of Ministry of Education under Grant No.CRKL190104 and Grant No.CRKL200107Open Foundation of State key Laboratory of Networking and Switching Technology under Grant No.SKLNST-2020-1-08(Beijing University of Posts and Telecommunications)。
文摘Low Earth orbit(LEO) satellite systems provide terrestrial users with services that are not limited by geographical location. However, the conflict between existing allocation schemes and the business variability between beams is becoming increasingly prominent. Beam hopping technology allows for a more flexible and versatile approach to satellite resource allocation. This paper proposes a beam hopping pattern optimization scheme that jointly considers the interference threshold distance and beam service priority, reducing the inter-beam co-channel interference(CCI). In the cluster area, a non-orthogonal multiple access(NOMA)-based collaborative beam hopping(NCBH) scheme is proposed to minimize the cell-edge user(CEU) interference. Since there is a difference in channel gain between the CEU and cellcenter user(CCU), this scheme forms a NOMA cluster to perform power domain multiplexing and formulates a NOMA cluster pairing strategy according to the user location to reduce the CCI of the CEU. After NOMA cluster pairing, the optimal carrier frequency of the NOMA cluster is selected by a reinforcement learning algorithm. The simulation results verify the excellent performance of the proposed NCBH scheme regarding the user’s received power, transmission rate, and outage probability.
文摘MARCH 9,2023 marks the 50th anniversary of the establishment of diplomatic relations between China and Spain.To gain more insight into the development of this relationship,China Today recently spoke to Wu Haitao,Chinese ambassador to Spain.According to Wu,the two sides have planned a series of celebrations for the occasion.
基金supported by National Natural Science Foundation of China(Nos.61861013,61662018)Science and Technology Major Project of Guangxi(No.AA18118031)+2 种基金Guangxi Natural Science Foundation of China(No.2018 GXNSFAA050028)the Doctoral Research Foundation of Guilin University of Electronic Science and Technology(No.UF19033Y)Director Fund project of Key Laboratory of Cognitive Radio and Information Processing of Ministry of Education(No.CRKL190102)。
文摘The proliferation of the global datasphere has forced cloud storage systems to evolve more complex architectures for different applications.The emergence of these application session requests and system daemon services has created large persistent flows with diverse performance requirements that need to coexist with other types of traffic.Current routing methods such as equal-cost multipath(ECMP)and Hedera do not take into consideration specific traffic characteristics nor performance requirements,which make these methods difficult to meet the quality of service(QoS)for high-priority flows.In this paper,we tailored the best routing for different kinds of cloud storage flows as an integer programming problem and utilized grey relational analysis(GRA)to solve this optimization problem.The resulting method is a GRAbased service-aware flow scheduling(GRSA)framework that considers requested flow types and network status to select appropriate routing paths for flows in cloud storage datacenter networks.The results from experiments carried out on a real traffic trace show that the proposed GRSA method can better balance traffic loads,conserve table space and reduce the average transmission delay for high-priority flows compared to ECMP and Hedera.
