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Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-α]quinoline moiety and their antimicrobial activity assess 被引量:7
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作者 Niraj K.Ladani Divyesh C.Mungra +1 位作者 manish p.patel Ranjan G.Patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2011年第12期1407-1410,共4页
Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[1,5-α]quinoline-4-carbal-dehyde, dimedone/cyclohexane-1,3-dione,ethyl/methyl acetoacetate and ammonium acetate was des... Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[1,5-α]quinoline-4-carbal-dehyde, dimedone/cyclohexane-1,3-dione,ethyl/methyl acetoacetate and ammonium acetate was described as the preparation of tetrazolo[1,5-α]quinoline based 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines.The process presented here is simple,rapid,environmentally welcoming and high yielding.All the derivatives were subjected to an in vitro antimicrobial screening against a representative panel of bacteria and fungi and results worth further investigations. 展开更多
关键词 Microwave assisted Tetrazolo[1 5-α]quinoline 1 4-Dihydropyridine Acridine-1 8-dione POLYHYDROQUINOLINE Antimicrobial activity
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One step synthesis of pyrido[1,2-a]benzimidazole derivatives of aryloxypyrazole and their antimicrobial evaluation 被引量:9
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作者 Hardik H.Jardosh Chetan B.Sangani +1 位作者 manish p.patel Ranjan G.Patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2013年第2期123-126,共4页
Received 3 September 2012 Received in revised form 16 October 2012 Accepted 31 December 2012 Available online 6 February 2013
关键词 AryloxypyrazolePyrido[ 1 2-a]benzimidazoleMulticomponent reactionAntimicrobial activity
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Molecular iodine catalyzed synthesis of tetrazolo[1,5-a]-quinoline based imidazoles as a new class of antimicrobial and antituberculosis agents 被引量:3
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作者 Divyesh C.Mungra Harshad G.Kathrotiya +2 位作者 Niraj K.Ladani manish p.patel Ranjan G.Patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第12期1367-1370,共4页
A series of some new tetrazolo[1,5-a]quinoline based tetrasubstituted imidazole derivatives 6a-i have been synthesized by a reaction of tetrazolo[ 1,5-a]quinoline-4-carbaldehyde 3a-d, benzil 4, aromatic amine 5a--c an... A series of some new tetrazolo[1,5-a]quinoline based tetrasubstituted imidazole derivatives 6a-i have been synthesized by a reaction of tetrazolo[ 1,5-a]quinoline-4-carbaldehyde 3a-d, benzil 4, aromatic amine 5a--c and ammonium acetate in the presence of iodine through one-pot multi-component reaction (MCR) approach. All the derivatives were screened for antimicrobial and antituberculosis activities and results worth further investigations. 展开更多
关键词 Tetrazolo[1 5-a]quinoline IMIDAZOLE MCR IODINE Antimicrobial activity Antituberculosis activity
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Synthesis and in vitro antimicrobial activity of N-arylquinoline derivatives bearing 2-morpholinoquinoline moiety 被引量:3
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作者 Jigar A.Makawana manish p.patel Ranjan G.Patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第4期427-430,共4页
A new series of N-arylquinoline derivatives 5a-x bearing 2-morpholinoquinoline moiety has been synthesized by one pot base catalyzed cyclocondensation reaction of 2-morpholinoquinoline-3-carbaldehydes 2a-c,malononitri... A new series of N-arylquinoline derivatives 5a-x bearing 2-morpholinoquinoline moiety has been synthesized by one pot base catalyzed cyclocondensation reaction of 2-morpholinoquinoline-3-carbaldehydes 2a-c,malononitrile 3 andβ-enaminones 4a-h. All the synthesized compounds were screened for their in vitro antimicrobial activity against six bacterial pathogens,namely Streptococcus pneumoniae,Clostridium tetani,Bacillus subtilis,Salmonella typhi,Vibrio cholerae,Escherichia coli and against two fungal pathogens,Aspergillus fumigatus and Candida albicans using broth microdilution MIC method.Of the compounds studied,majority of the compounds were found to active against C.tetani,B.subtilis and C.albicans as compared to first-line standard drugs. 展开更多
关键词 N-arylquinoline 2-Morpholinoquinoline-3-carbaldehyde In vitro antimicrobial activity MCR
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An efficient synthesis of 3'-quinolinyl substituted imidazole-5-one derivatives catalyzed by zeolite and their antimicrobial activity 被引量:3
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作者 Harshad G.Kathrotiya Nilav A.Patel +1 位作者 Ranjan G.Patel manish p.patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第3期273-276,共4页
A series of some new quinoline based imidazole-5-one derivatives have been synthesized by the fusion of oxazol-5-ones,various p-substituted anilines and zeolite in pyridine.All the derivatives were subjected to an in ... A series of some new quinoline based imidazole-5-one derivatives have been synthesized by the fusion of oxazol-5-ones,various p-substituted anilines and zeolite in pyridine.All the derivatives were subjected to an in vitro antimicrobial screening against a representative panel of bacteria and fungi and results worth further investigations. 展开更多
关键词 IMIDAZOLINONE QUINOLINE ZEOLITE Antimicrobial activity
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A new fast swelling poly[DAPB-co-DMAAm-co-AASS] superabsorbent hydrogel for removal of anionic dyes from water 被引量:5
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作者 Yatin N.Patel manish p.patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2013年第11期1005-1007,共3页
The objective of this research is to utilize a new poly[N,N-diallyl pyrrolidinium bromide-co-N,Ndimethyl acrylamide-co-acrylic acid sodium salt]superabsorbent hydrogel(SAH)for the removal of two anionic dyes,e.g.,Re... The objective of this research is to utilize a new poly[N,N-diallyl pyrrolidinium bromide-co-N,Ndimethyl acrylamide-co-acrylic acid sodium salt]superabsorbent hydrogel(SAH)for the removal of two anionic dyes,e.g.,Reactive Red 5B(RR5B)and Reactive Orange M2R(ROM2R),from water.The SAH was characterized by swelling in water,FTIR,TGA and SEM.The SAH DDA6showed good swelling property and thermal stability.We have also investigated the parameters affecting dye adsorption such as pH,adsorbent dose,adsorption rate and initial dye concentration.The experimental data were also analyzed by applying the well known Langmuir and Freundlich isotherm models. 展开更多
关键词 Superabsorbent hydrogel Anionic dyes Dye adsorption Adsorption isotherm
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Synthesis of new superabsorbent poly(NIPAAm/AA/N-allylisatin)nanohydrogel for effective removal of As(Ⅴ) and Cd(Ⅱ) toxic metal ions 被引量:5
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作者 Viran P.Mahida manish p.patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2014年第4期601-604,共4页
The present studies highlight the effective removal of As(V) and Cd(II) from aqueous solutions by superabsorbent poly (NIPAAm/AA/N-allylisatin) nanohydrogel. Batch removal studies were performed as a function of... The present studies highlight the effective removal of As(V) and Cd(II) from aqueous solutions by superabsorbent poly (NIPAAm/AA/N-allylisatin) nanohydrogel. Batch removal studies were performed as a function of treatment time, initial metal ion concentration, pH, and adsorbent dose. TEM micrographs confirm the particle size distribution in the range between 5 nm and 10 rim. The simple and metal ions adsorbed nanohydrogels were characterized by FF-IR, TGA, and EDX analysis. Finally, the equilibrium removal efficiency of the nanohydrogel was analyzed according to the Langmuir and Freundlich adsorption isotherm models which showed the removal of As(V) and Cd(II) metal ions fitted to Freundlich and Langmuir isotherms, respectively. Removal efficiency order of the metal ions is As(V) 〉 Cd(II). 展开更多
关键词 Removal Toxic metal ions Superabsorbent Nanohydrogel
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PS-TBD triggered general protocol for the synthesis of 4H-chromene,pyrano[4,3-b]pyran and pyrano[3,2-c]chromene derivatives of 1H-pyrazole and their biological activities 被引量:1
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作者 Nileshkumar D.Vala Hardik H.Jardosh manish p.patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2016年第1期168-172,共5页
A general protocol has been developed for the facile construction of titled derivatives via three component reaction between 3-substituted phenyl-1H-pyrazole-4-carbaldehyde, malononitrile and various Michael donors in... A general protocol has been developed for the facile construction of titled derivatives via three component reaction between 3-substituted phenyl-1H-pyrazole-4-carbaldehyde, malononitrile and various Michael donors in presence of 5 mol% polystyrene supported 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene(PS-TBD). PS-TBD was reused for at least five runs with nearly constant catalytic activity. All compounds were screened for antimicrobial and antioxidant activities. 展开更多
关键词 PS-TBD 1H-Pyrazole Antimicrobial activity Antioxidant activity
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Synthesis of N-arylquinolone derivatives bearing 2-thiophenoxyquinolines and their antimicrobial evaluation 被引量:1
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作者 Mehul B.Kanani manish p.patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2014年第7期1073-1076,共4页
A new series of 2-thiophenoxyquinolines based trifluoromethyl substituted N-aryl quinolone derivatives 8a-f and 9a-f have been synthesized via a one-pot multicomponent reaction. In vitro antimicrobial activity of the ... A new series of 2-thiophenoxyquinolines based trifluoromethyl substituted N-aryl quinolone derivatives 8a-f and 9a-f have been synthesized via a one-pot multicomponent reaction. In vitro antimicrobial activity of the synthesized compounds was investigated against a representative panel of pathogenic strains. Compounds 8c, 9c and 9e exhibited comparable antimicrobial activity to first line drugs. 展开更多
关键词 2-Thiophenoxyquinoline TRIFLUOROMETHYL N-Aryl quinolone Antimicrobial activity
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Synthesis,characterization and antimicrobial activity of some new biquinoline derivatives containing a thiazole moiety 被引量:1
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作者 Nirav K.Shah Nimesh M.Shah +1 位作者 manish p.patel Ranjan G.Patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第4期454-457,共4页
A series of new biquinoline derivatives containing a thiazole moiety were synthesized by a one-pot,base-catalyzed cyclocondensation reaction of 2-chloro-3-formyl quinoline,malononitrile and enaminone.All the synthesiz... A series of new biquinoline derivatives containing a thiazole moiety were synthesized by a one-pot,base-catalyzed cyclocondensation reaction of 2-chloro-3-formyl quinoline,malononitrile and enaminone.All the synthesized compounds were characterized by elemental analysis,FT-IR,~1H NMR and ^(13)C NMR data.All the synthesized compounds were screened against three bacterial pathogens,namely Bacillus cereus,B.substilis and Escherichia coli and for antifungal activity against three fungal pathogens,Aspergillus niger,Fusarium oxisporum and Rhizopus using the disc diffusion method. 展开更多
关键词 QUINOLINE Multicomponent reaction THIAZOLE Antimicrobial activity
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Synthesis and in vitro antimicrobial screening of new pyrano[4,3-b]pyrane derivatives of 1H-pyrazole 被引量:4
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作者 Chetan B.Sangani Divyesh C.Mungra +1 位作者 manish p.patel Ranjan G.Patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第1期57-60,共4页
A new series of pyrano[4,3-b]pyrane 4a-l bearing 1H-pyrazole has been synthesized by one pot base catalyzed cyclocondensation reaction of 1H-pyrazole-4-carbaldehyde la-1,malononitrile 2 and 4-hydroxy-6-methylpyrone 3.... A new series of pyrano[4,3-b]pyrane 4a-l bearing 1H-pyrazole has been synthesized by one pot base catalyzed cyclocondensation reaction of 1H-pyrazole-4-carbaldehyde la-1,malononitrile 2 and 4-hydroxy-6-methylpyrone 3.All the synthesized compounds were screened against six bacterial pathogens,namely B.subtilis,C.tetani,S.pneumoniae,S.typhi,V.cholerae, E.coli and antifungal activity against,two fungal pathogens,A.fumigatus and C.albicans using broth microdilution MIC method. Some of the compounds are found to be equipotent or more potent than that of commercial drugs,against most of employed strains. 展开更多
关键词 Pyranopyrane MCR Pyrazole-4-carbaldehyde Antimicrobial activity
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Superabsorbent amphoteric nanohydrogels: Synthesis,characterization and dyes adsorption studies
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作者 Viran P.Mahida manish p.patel 《Chinese Chemical Letters》 SCIE CAS CSCD 2016年第3期471-474,共4页
The goal of the present research is to remove high percentage of cationic and anionic dyes such as,Neutral Red, Safranin O and Indigo Carmine from aqueous solutions by poly(NIPAAm/N,Ndiallylpyrrolidinium bromide/AA)... The goal of the present research is to remove high percentage of cationic and anionic dyes such as,Neutral Red, Safranin O and Indigo Carmine from aqueous solutions by poly(NIPAAm/N,Ndiallylpyrrolidinium bromide/AA) superabsorbent amphoteric nanohydrogels synthesized using the inverse microemulsion polymerization method. Effect of various parameters such as, treatment time,initial dye concentration, p H and adsorbent dose were investigated. Furthermore, kinetics and isotherms adsorption models were applied to determine the maximum adsorption and mechanism for adsorption,which shows that adsorption obeyed the pseudo-second order kinetics. From the results, removal of dyes within the nanohydrogel was found to be in the order: AB-74 〈 BR-2≤ BR-5. 展开更多
关键词 Adsorption Dyes Superabsorbent Nanohydrogel
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