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Effect of antenna helicity on discharge characteristics of helicon plasma under a divergent magnetic field
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作者 孙萌 徐晓芳 +3 位作者 王陈文 尹贤轶 陈强 张海宝 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第6期50-59,共10页
The characteristics of the blue core phenomenon observed in a divergent magnetic field helicon plasma are investigated using two different helical antennas, namely right-handed and lefthanded helical antennas. The mod... The characteristics of the blue core phenomenon observed in a divergent magnetic field helicon plasma are investigated using two different helical antennas, namely right-handed and lefthanded helical antennas. The mode transition, discharge image, spatial profiles of plasma density and electron temperature are diagnosed using a Langmuir probe, a Nikon D90 camera,an intensified charge-coupled device camera and an optical emission spectrometer, respectively.The results demonstrated that the blue core phenomenon appeared in the upstream region of the discharge tube at a fixed magnetic field under both helical antennas. However, it is more likely to appear in a right-handed helical antenna, in which the plasma density and ionization rate of the helicon plasma are higher. The spatial profiles of the plasma density and electron temperature are also different in both axial and radial directions for these two kinds of helical antenna. The wavelength calculated based on the dispersion relation of the bounded whistler wave is consistent with the order of magnitude of plasma length. It is proved that the helicon plasma is part of the wave mode discharge mechanism. 展开更多
关键词 helicon plasma non-uniform magnetic field helical antenna blue core discharge mechanism
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Dielectric barrier discharge plasma-assisted catalytic ammonia synthesis:synergistic effect of Ni-MOF-74 catalyst and nanosecond pulsed plasma
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作者 徐晓芳 孙萌 +4 位作者 宋勤龙 吴璇 陈冲冲 陈强 张海宝 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第6期40-49,共10页
Ammonia is one of the most important chemical raw materials in both manufacture and life of human.Traditionally Haber-Bosch method for ammonia synthesis involves high temperature and high pressure conditions,leading t... Ammonia is one of the most important chemical raw materials in both manufacture and life of human.Traditionally Haber-Bosch method for ammonia synthesis involves high temperature and high pressure conditions,leading to significant energy consumption and environmental pollution.Non-thermal plasma(NTP) is a promising alternative approach to ammonia synthesis at low temperature and atmospheric pressure.In this study,the synergistic effect of nanosecond pulsed dielectric barrier discharge(np-DBD) and Ni-MOF-74 catalyst was investigated in ammonia synthesis by utilizing nitrogen and hydrogen as feedstock.The results demonstrated that the plasma catalytic-synthesis process parameters play a crucial role in the synthesis process of ammonia.The highest ammonia synthesis rate of 5145.16 μmol·g^(-1)·h^(-1)with an energy efficiency of 1.27 g·kWh^(-1)was observed in the presence of the Ni-MOF-74 catalyst,which was3.7 times higher than that without Ni-MOF-74 catalyst.The synergistic effect of Ni-MOF-74catalyst and nanosecond pulsed plasma was explored by in-situ plasma discharge diagnostics. 展开更多
关键词 AMMONIA SYNTHESIS low-temperature plasma nanosecond pulsed power source Ni-MOF-74
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The dawn−dusk asymmetry in mesosphere and lower thermosphere temperature disturbances during geomagnetic storms at high latitude
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作者 GuanChun Wei JianYong Lu +2 位作者 Fen Tang JingYuan Li meng sun 《Earth and Planetary Physics》 EI CAS CSCD 2024年第2期356-367,共12页
Utilizing observations by the Sounding of the Atmosphere using Broadband Emission Radiometry(SABER)instrument,we quantitatively assessed the dawn-dusk asymmetry in temperature disturbances within the high-latitude mes... Utilizing observations by the Sounding of the Atmosphere using Broadband Emission Radiometry(SABER)instrument,we quantitatively assessed the dawn-dusk asymmetry in temperature disturbances within the high-latitude mesosphere and lower thermosphere(MLT)during the main phase of geomagnetic storms in this study.An analysis of five geomagnetic superstorm events indicated that during the main phase,negative temperature disturbances were more prevalent on the dawn side than on the dusk side in the high-latitude MLT region.Results of a statistical analysis of 54 geomagnetic storm events also revealed a notable disparity in temperature disturbances between the dawn and dusk sides.At high latitudes,38.2%of the observational points on the dawn side exhibited negative temperature disturbances(less than−5 K),whereas on the dusk side,this percentage was only 29.5%.In contrast,at mid-latitudes,these proportions were 34.1%and 36.5%,respectively,showing no significant difference.We also conducted a statistical analysis of temperature disturbances at different altitudes,which revealed an increase in the proportion of warming disturbances with altitude.Conversely,the proportion of cooling disturbances initially rose with altitude,reaching a peak around 105 km,and subsequently decreased.These temperature disturbance differences could be explained by the day-night asymmetry in vertical wind disturbances during storm conditions. 展开更多
关键词 DAWN dusk asymmetry SABER(Sounding of the Atmosphere using Broadband Emission Radiometry) geomagnetic storms mesosphere and lower thermosphere
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Pre-training transformer with dual-branch context content module for table detection in document images
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作者 Yongzhi LI Pengle ZHANG +2 位作者 meng sun Jin HUANG Ruhan HE 《虚拟现实与智能硬件(中英文)》 EI 2024年第5期408-420,共13页
Background Document images such as statistical reports and scientific journals are widely used in information technology.Accurate detection of table areas in document images is an essential prerequisite for tasks such... Background Document images such as statistical reports and scientific journals are widely used in information technology.Accurate detection of table areas in document images is an essential prerequisite for tasks such as information extraction.However,because of the diversity in the shapes and sizes of tables,existing table detection methods adapted from general object detection algorithms,have not yet achieved satisfactory results.Incorrect detection results might lead to the loss of critical information.Methods Therefore,we propose a novel end-to-end trainable deep network combined with a self-supervised pretraining transformer for feature extraction to minimize incorrect detections.To better deal with table areas of different shapes and sizes,we added a dualbranch context content attention module(DCCAM)to high-dimensional features to extract context content information,thereby enhancing the network's ability to learn shape features.For feature fusion at different scales,we replaced the original 3×3 convolution with a multilayer residual module,which contains enhanced gradient flow information to improve the feature representation and extraction capability.Results We evaluated our method on public document datasets and compared it with previous methods,which achieved state-of-the-art results in terms of evaluation metrics such as recall and F1-score.https://github.com/Yong Z-Lee/TD-DCCAM. 展开更多
关键词 Table detection Document image analysis TRANSFORMER Dilated convolution Deformable convolution Feature fusion
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人工智能与教育:本质探析和未来挑战 被引量:18
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作者 韦恩·霍姆斯 孙梦 袁莉 《中国教育信息化》 2023年第2期16-26,共11页
当前,虽然有研究人员认为人工智能将重塑教育,关于人工智能教育的研究也日益受到关注和重视,但是人工智能在教育中的应用仍存在“炒作”现象,一些乐观看法还亟待商榷,一些关键问题还需要探析和解决。为此,文章首先探讨了人工智能的定义... 当前,虽然有研究人员认为人工智能将重塑教育,关于人工智能教育的研究也日益受到关注和重视,但是人工智能在教育中的应用仍存在“炒作”现象,一些乐观看法还亟待商榷,一些关键问题还需要探析和解决。为此,文章首先探讨了人工智能的定义,提出人工智能本质上应同时考虑其技术维度和人的维度;然后进一步分析人工智能与教育的关系,并从人工智能教育与教学法,伦理,儿童权益,个性化,节约教师时间,智能、效能和影响,技术解方主义,教育商业化,殖民主义,信任等十个方面,思考人工智能教育表象下存在的问题。据此提出,虽然人们已经意识到教育中人工智能伦理和人本主义等问题的重要性,但由于人工智能的发展方向受科技巨头企业的控制,这些问题的解决还有很长的路要走。文章希望通过对人工智能教育本质的探讨,促使更多研究者和实践者不只关注人工智能教育的表面价值,更要去发现、思考和应对正在出现和仍然未知的挑战。 展开更多
关键词 人工智能 人工智能教育 人工智能素养 人工智能伦理 未来挑战
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Effect of neutral pressure on the blue core in Ar helicon plasma under an inhomogeneous magnetic field 被引量:1
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作者 王陈文 刘洋 +4 位作者 孙萌 张天亮 谢俊发 陈强 张海宝 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第4期93-100,共8页
The effect of neutral pressure on the blue core in Ar helicon plasma under an inhomogeneous magnetic field was investigated in this work.The neutral pressure was set to 0.08 Pa,0.36 Pa,and 0.68 Pa.A Nikon camera,inten... The effect of neutral pressure on the blue core in Ar helicon plasma under an inhomogeneous magnetic field was investigated in this work.The neutral pressure was set to 0.08 Pa,0.36 Pa,and 0.68 Pa.A Nikon camera,intensified charge-coupled device(ICCD),optical emission spectrometer(OES),and Langmuir probe were used to diagnose the blue core in helicon plasma.Helicon plasma discharges experienced density jumps from the E mode,H mode to W mode before power just rose to 200 W.The plasma density increased and maintained a central peak with the increase of neutral pressure.However,the brightness of the blue core gradually decreased.It is demonstrated that the relative intensity of Ar II spectral lines and the ionization rate in the central area were reduced.Radial electron temperature profiles were flattened and became hollow as neutral pressure increased.It is demonstrated that increasing the neutral pressure weakened the central heating efficiency dominated by the helicon wave and strengthened the edge heating efficiency governed by the TG wave and skin effect.Therefore,the present experiment successfully reveals how the neutral pressure affects the heating mechanism of helicon plasma in an inhomogeneous magnetic field. 展开更多
关键词 helicon plasma blue core neutral pressure heating mechanism edge heating
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Removal of Stripes in Remote Sensing Images Based on Statistics Combined with Image Enhancement 被引量:1
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作者 Xiaofei QU Weiwei ZHAO +2 位作者 En LONG meng sun Guangling LAI 《Journal of Geodesy and Geoinformation Science》 CSCD 2023年第1期76-87,共12页
A method to remove stripes from remote sensing images is proposed based on statistics and a new image enhancement method.The overall processing steps for improving the quality of remote sensing images are introduced t... A method to remove stripes from remote sensing images is proposed based on statistics and a new image enhancement method.The overall processing steps for improving the quality of remote sensing images are introduced to provide a general baseline.Due to the differences in satellite sensors when producing images,subtle but inherent stripes can appear at the stitching positions between the sensors.These stitchingstripes cannot be eliminated by conventional relative radiometric calibration.The inherent stitching stripes cause difficulties in downstream tasks such as the segmentation,classification and interpretation of remote sensing images.Therefore,a method to remove the stripes based on statistics and a new image enhancement approach are proposed in this paper.First,the inconsistency in grayscales around stripes is eliminated with the statistical method.Second,the pixels within stripes are weighted and averaged based on updated pixel values to enhance the uniformity of the overall image radiation quality.Finally,the details of the images are highlighted by a new image enhancement method,which makes the whole image clearer.Comprehensive experiments are performed,and the results indicate that the proposed method outperforms the baseline approach in terms of visual quality and radiation correction accuracy. 展开更多
关键词 remote sensing images stripe removal STATISTICS image enhancement
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基于年龄分层的子宫内膜息肉患者治疗及随访分析
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作者 孙梦 王元 《中外女性健康研究》 2023年第4期18-21,共4页
目的:探究不同年龄子宫内膜息肉患者行宫腔镜子宫内膜息肉切除术治疗的临床疗效及随访分析。方法:选取2020年1月至2021年12月本院收治确诊的子宫内膜息肉患者383例,按照年龄分为四组:≤30岁、31~35岁、36~45岁、≥46岁年龄组,评价疗效... 目的:探究不同年龄子宫内膜息肉患者行宫腔镜子宫内膜息肉切除术治疗的临床疗效及随访分析。方法:选取2020年1月至2021年12月本院收治确诊的子宫内膜息肉患者383例,按照年龄分为四组:≤30岁、31~35岁、36~45岁、≥46岁年龄组,评价疗效及随访预后。结果:(1)约46%的年轻女性(≤30岁)行宫腔镜下冷刀息肉切除术。术后54%的患者选择药物治疗。约68%的31~35岁女性行宫腔镜下子宫内膜息肉电切术,术后曼月乐环置入率约为28%。对于36~45岁组,术后曼月乐环置入率为66%。对于46岁以上年龄组,约80%行宫腔镜下根治性息肉电切术或诊刮后电切术。(2)单因素分析表明,年龄是影响患者住院时间的相关因素。(3)各年龄段患者术后子宫内膜厚度较术前均明显减小,月经量较前减少,有统计学差异。结论:宫腔镜下子宫内膜息肉切除术对于异常子宫出血、宫腔占位的诊治疗效确切。临床医师对于子宫内膜息肉患者需采取个体化的治疗方案并规范术后的长期管理。 展开更多
关键词 子宫内膜息肉 宫腔镜子宫内膜息肉切除术 年龄 曼月乐 预后 个体化
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融合纳米囊泡在癌症治疗中的研究进展
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作者 孙梦 樊玥芸 +2 位作者 杨佳妮 胡敏 张金凤 《生命科学仪器》 2023年第6期22-29,共8页
细胞外囊泡(Extracellular vesicles,EVs)凭借其天然的生物学特性和后天获得的多功能优势,逐渐参与到机体调节的生理及病理过程中,成为疾病预防、治疗、评估的有力工具。癌症是目前危害人类健康的重大疾病之一,其临床治疗手段主要依靠... 细胞外囊泡(Extracellular vesicles,EVs)凭借其天然的生物学特性和后天获得的多功能优势,逐渐参与到机体调节的生理及病理过程中,成为疾病预防、治疗、评估的有力工具。癌症是目前危害人类健康的重大疾病之一,其临床治疗手段主要依靠放化疗、手术切除及新兴的免疫治疗。然而,以上治疗方式存在药物毒副作用强、生物利用度低、治疗成本昂贵、易复发等不足,极大影响癌症的治疗进展。因此,EVs的出现为癌症治疗提供了更加安全、高效的治疗策略,但天然产生的单一EVs产量低、自体靶向能力弱且载药能力低,在疾病治疗临床转化方面的发展受限。因此,建立普适性强且灵活性好的多功能融合纳米囊泡是扩大EVs实际效用的关键。本综述系统地总结了融合纳米囊泡的制备方法、分类特点、在癌症治疗中的应用及面临的挑战,为开发有前途的精准医疗纳米平台提供理论指导。 展开更多
关键词 细胞外囊泡 外泌体 融合纳米囊泡 膜融合 癌症治疗
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Jasmonic acid-mediated stress responses share the molecular mechanism underlying male sterility induced by deficiency of ZmMs33 in maize
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作者 Ziwen Li Shuangshuang Liu +7 位作者 Taotao Zhu Jing Wang meng sun Xueli An Xun Wei Cuimei Liu Jinfang Chu Xiangyuan Wan 《The Crop Journal》 SCIE CSCD 2023年第4期1115-1127,共13页
Plant male reproduction is a fine-tuned developmental process that is susceptible to stressful environments and influences crop grain yields.Phytohormone signaling functions in control of plant normal growth and devel... Plant male reproduction is a fine-tuned developmental process that is susceptible to stressful environments and influences crop grain yields.Phytohormone signaling functions in control of plant normal growth and development as well as in response to external stresses,but the interaction or crosstalk among phytohormone signaling,stress response,and male reproduction in plants remains poorly understood.Cross-species comparison among 514 stress-response transcriptomic libraries revealed that ms33-6038,a genic male sterile mutant deficient in the Zm Ms33/Zm GPAT6 gene,displayed an excessive drought stress-like transcriptional reprogramming in anthers triggered mainly by disturbed jasmonic acid(JA)homeostasis.An increased level of JA appeared in Zm Ms33-deficient anthers at both meiotic and postmeiotic stages and activated genes involved in JA biosynthesis and signaling as well as genes functioning in JA-mediated drought response.Excessive accumulation of JA elevated expression level of a gene encoding a WRKY transcription factor that activated the Zm Ms33 promoter.These findings reveal a feedback loop of Zm Ms33-JA-WRKY-Zm Ms33 in controlling male sterility and JA-mediated stress response in maize,shedding light on the crosstalk of stress response and male sterility mediated by phytohormone homeostasis and signaling. 展开更多
关键词 ZmMs33/ZmGPAT6 Jasmonic acid Phytohormone homeostasis Male sterility Stress response
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Identification and expression analysis of chlorogenic acid biosynthesis key gene PpHCT in peach
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作者 Ziwen Su meng sun +7 位作者 Zhixiang Cai Shaolei Guo Jiyao Li Bintao Zhao Zhijun Shen Ruijuan Ma Juan Yan Mingliang Yu 《Horticultural Plant Journal》 SCIE CAS CSCD 2023年第4期670-680,共11页
Shikimic acid/quinic acid hydroxy cinnamyl transferase(HCT)is one of the key enzymes in the phenylpropanoid pathway.However,the role of the HCT gene in chlorogenic acid(CGA)biosynthesis in peach fruit remains unclear.... Shikimic acid/quinic acid hydroxy cinnamyl transferase(HCT)is one of the key enzymes in the phenylpropanoid pathway.However,the role of the HCT gene in chlorogenic acid(CGA)biosynthesis in peach fruit remains unclear.For this,we identified the accumulation pattern of CGA in four peach cultivars,cloned and characterized 11 PpHCT gene members,and further analyzed the expression patterns of these PpHCT genes during fruit development.The contents of CGAs in the four peach cultivars all exhibited a trend of increasing and then decreasing during the fruit growth and development.Moreover,the contents of CGAs in the peel and flesh were tissue-specific.Gene structure analysis indicated that the PpHCT genes were highly conserved,containing two exons and one intron.The protein structure analysis demonstrated that the PpHCT proteins contained two conserved motifs(HXXXD,DFGWG)and a transferase domain(PF02458),which belonged to the BAHD acyltransferase family.The cis-acting element analysis suggested that the promoters of PpHCT genes contained many light-related,hormone-related,stress-related,tissue-specific,and circadian-related elements,and they could participate in a variety of biological processes.Phylogenetic analysis showed that the HCT proteins of peach were closely related to the HCT proteins of plum and had a close evolutionary relationship.The qRT-PCR analysis indicated that the expression levels of PpHCT1 and PpHCT2 showed an opposite trend to the accumulation of CGA,whereas the expression levels of PpHCT4,PpHCT5,PpHCT7,PpHCT8,and PpHCT11 demonstrated the same trend as CGA accumulation.It was worth noting that only PpHCT4 and PpHCT5 were highly expressed in the two high-CGA cultivars but showed low levels of expression in the two low-CGA cultivars.Therefore,it was hypothesized that these two genes might be key genes to the synthesis of CGA in peach fruit.Those findings provide a theoretical basis for further study on the biological functions of the HCT gene and help to reveal the molecular mechanism of CGA. 展开更多
关键词 Prunus persica(L.) Chlorogenic acid PpHCT Bioinformatics analysis Gene expression
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Modeling Cyber Loss Severity Using a Spliced Regression Distribution with Mixture Components
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作者 meng sun 《Open Journal of Statistics》 2023年第4期425-452,共28页
Cyber losses in terms of number of records breached under cyber incidents commonly feature a significant portion of zeros, specific characteristics of mid-range losses and large losses, which make it hard to model the... Cyber losses in terms of number of records breached under cyber incidents commonly feature a significant portion of zeros, specific characteristics of mid-range losses and large losses, which make it hard to model the whole range of the losses using a standard loss distribution. We tackle this modeling problem by proposing a three-component spliced regression model that can simultaneously model zeros, moderate and large losses and consider heterogeneous effects in mixture components. To apply our proposed model to Privacy Right Clearinghouse (PRC) data breach chronology, we segment geographical groups using unsupervised cluster analysis, and utilize a covariate-dependent probability to model zero losses, finite mixture distributions for moderate body and an extreme value distribution for large losses capturing the heavy-tailed nature of the loss data. Parameters and coefficients are estimated using the Expectation-Maximization (EM) algorithm. Combining with our frequency model (generalized linear mixed model) for data breaches, aggregate loss distributions are investigated and applications on cyber insurance pricing and risk management are discussed. 展开更多
关键词 Cyber Risk Data Breach Spliced Regression Model Finite Mixture Distribu-tion Cluster Analysis Expectation-Maximization Algorithm Extreme Value Theory
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睡眠障碍与脑卒中患者抑郁的相关性研究 被引量:36
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作者 焦传安 张自学 +6 位作者 吴本波 唐述龙 李军 孙萌 杨克非 蒋凯 焦龙 《中国现代医学杂志》 CAS 2019年第10期86-90,共5页
目的探讨睡眠障碍与脑卒中患者抑郁的相关性。方法选取2016年1月—2017年12月于安徽医科大学附属巢湖医院收治的138例初发脑卒中康复期患者作为研究对象,采用抑郁自评量表(SDS)、匹兹堡睡眠量表指数量表(PSQI)分别评价脑卒中患者的抑郁... 目的探讨睡眠障碍与脑卒中患者抑郁的相关性。方法选取2016年1月—2017年12月于安徽医科大学附属巢湖医院收治的138例初发脑卒中康复期患者作为研究对象,采用抑郁自评量表(SDS)、匹兹堡睡眠量表指数量表(PSQI)分别评价脑卒中患者的抑郁状况和睡眠质量,根据SDS评分诊断患者脑卒中后抑郁(PSD),分析睡眠障碍与PSD的关系,采用多因素Logistic回归探讨PSD发生的影响因素,采用Pearson相关性分析探讨患者SDS与PSQI评分的关系。结果离异或丧偶、伴有糖尿病史、出血性脑卒中、脑卒中位于皮质下、左半球、无定期进行康复锻炼、自理能力明显障碍、有睡眠障碍患者的发生PSD发生率均有升高(P <0.05)。多因素Logistic回归结果表明婚姻状况[OlR=2.517,(95 CI:1.133,5.594),P=0.023]、脑卒中类型[OlR=1.126,(95 CI:1.005,1.262),P=0.041]、康复锻炼状况[OlR=1.283,(95 CI:1.024,1.607),P=0.030]、自理能力明显障碍[OlR=2.942,(95 CI:1.291,6.707),P=0.010]、睡眠障碍[OlR=1.585,(95CI:1.105,2.273),P=0.012]是患者发生PSD的关键的独立危险因素。SDS评分与主观睡眠障碍、睡眠效率、睡眠障碍及日间功能障碍均呈正相关(r=0.303、0.178、0.269和0.208,P=0.000、0.037、0.001和0.014)。SDS评分与主观睡眠障碍、睡眠效率、睡眠障碍及日间功能障碍均呈正相关(r=0.303、0.178、0.269和0.208,P<0.05)。结论脑卒中康复期患者容易发生睡眠障碍,睡眠障碍与PSD发生具有一定的相关性,且睡眠质量越差,抑郁表现越严重。 展开更多
关键词 抑郁 卒中 睡眠障碍
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妊娠糖尿病患者血清Betatrophin、Omentin-1水平与糖脂代谢及胰岛素抵抗的相关性 被引量:24
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作者 司凡 陈妍 +3 位作者 孙萌 陆宏燕 寇伟鑫 许丽丽 《中国现代医学杂志》 CAS 北大核心 2021年第15期26-30,共5页
目的探讨妊娠糖尿病(GDM)患者血清Betatrophin、脂肪组织中网膜素1(Omentin-1)水平变化特点,分析其与糖脂代谢和胰岛素抵抗的相关性。方法选择2019年5月—2020年8月承德市中心医院妇产科接诊的179例孕妇。采用酶联免疫吸附试验检测所有... 目的探讨妊娠糖尿病(GDM)患者血清Betatrophin、脂肪组织中网膜素1(Omentin-1)水平变化特点,分析其与糖脂代谢和胰岛素抵抗的相关性。方法选择2019年5月—2020年8月承德市中心医院妇产科接诊的179例孕妇。采用酶联免疫吸附试验检测所有孕妇妊娠10~14周血清Betatrophin、Omentin-1水平。所有孕妇妊娠24~26周进行口服葡萄糖糖耐量试验(OGTT),其中,119例被诊断为GDM(GDM组),60例血糖水平正常的孕妇为对照组。检测两组孕妇的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FBG)、空腹胰岛素(FINS)及糖化血红蛋白(HbA1c)水平。采用稳态模型计算胰岛素抵抗指数(HOMA-IR)。分析Betatrophin、Omentin-1与GDM患者糖脂代谢指标的相关性。多元线性逐步回归分析GDM患者HOMA-IR的影响因素。结果GDM组孕前体重指数(BMI)、FBG、FINS、HOMA-IR、HbA1c、TC、LDL-C、Betatrophin水平高于对照组(P<0.05),Omentin-1水平低于对照组(P<0.05)。相关性分析结果显示GDM患者血清Betatrophin与TG(rs=0464)、HOMA-IR(r=0.610)、LDL-C(r=0.512)呈正相关(均P<0.05),Omentin-1水平与孕前BMI(rs=-0.304)、LDL-C(r=-0.543)、FBG(r=-0.475)、FINS(r=-0.435)、HOMA-IR(r=-0.576)呈负相关(均P<0.05)。多元线性逐步回归分析结果显示TG、LDL-C、Betatrophin、Omentin-1是GDM患者HOMA-IR的影响因素(P<0.05)。结论GDM患者血清Betatrophin水平升高,Omentin-1水平降低,Betatrophin、Omentin-1均与GDM患者糖脂代谢、胰岛素抵抗有关。 展开更多
关键词 妊娠糖尿病 Betatrophin OMENTIN-1 糖脂代谢 胰岛素抵抗
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A Case of Pelvic Floor Peritoneal Hernia after Miles’ Surgery
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作者 Zhengwen Xu Fugen Li +3 位作者 meng sun Chuan Qian Wenjun Luo Xiaorong Zhu 《Surgical Science》 2022年第4期246-250,共5页
Objective: To investigate the causes and preventive measures of pelvic floor peritoneal hernia after transabdominal perineal radical resection of rectal cancer. Patients and Methods: A 68-year-old patient with progres... Objective: To investigate the causes and preventive measures of pelvic floor peritoneal hernia after transabdominal perineal radical resection of rectal cancer. Patients and Methods: A 68-year-old patient with progressive exacerbation of Miles’ postoperative intestinal obstruction was retrospectively analyzed. Conservative treatment was ineffective, and surgery was performed again. Surgery confirmed that the obstruction was caused by a pelvic floor peritoneal hernia. The original reconstruction peritoneal suture needle spacing was too wide, resulting in peritoneal hiatus. Results: The early postoperative intestinal obstruction in this patient was not caused by inflammatory intestinal obstruction, stenosis of stoma, and intestinal adhesion, but by the formation of pelvic floor peritoneal hernia. Conclusion: Pelvic floor peritoneal hernia should not be ignored in the early stage of intestinal obstruction after Miles’ operation. Improper suture during pelvic floor peritoneal reconstruction is the main cause of pelvic floor peritoneal hernia. 展开更多
关键词 Miles’ Operation Pelvic Floor Peritoneal Hernia Intestinal Obstruction
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间充质干细胞来源的胞外囊泡在急性肝衰竭治疗中的研究进展
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作者 李敏 孙梦 +2 位作者 马小岚 胡敏 张金凤 《生命科学仪器》 2022年第3期23-32,共10页
急性肝衰竭(Acute liver failure,ALF)是指无肝脏基础疾病而在短时间内发生大量肝细胞坏死及严重肝功能损害,并引起多器官障碍的危重临床综合征。ALF的病死率较高,但临床上还没有特效的治疗方法。因此,开发新的治疗手段来有效缓解肝衰... 急性肝衰竭(Acute liver failure,ALF)是指无肝脏基础疾病而在短时间内发生大量肝细胞坏死及严重肝功能损害,并引起多器官障碍的危重临床综合征。ALF的病死率较高,但临床上还没有特效的治疗方法。因此,开发新的治疗手段来有效缓解肝衰竭的进展是研究者普遍关注且亟需解决的关键问题。目前临床前研究的方法中,干细胞疗法被认为是治疗肝衰竭最有潜力的方法。但干细胞固有的临床风险阻滞了它的进一步应用,加上越来越多的证据表明,干细胞的生物学功能在很大程度上归功于其分泌的胞外囊泡(Extracellular vesicles,EVs)。EVs作为细胞自然产生的纳米级囊泡,已经成为ALF治疗中最具吸引力的纳米治疗手段之一。本文主要综述了EVs的形成、组分与分离,以及EVs在ALF治疗中的潜在机制。 展开更多
关键词 急性肝衰竭 胞外囊泡 免疫调节 再生 氧化应激
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Influence of crucible material on inclusions in 95Cr saw-wire steel deoxidized by Si–Mn 被引量:7
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作者 Yang Li Chang-yong Chen +3 位作者 Guo-qing Qin Zhou-hua Jiang meng sun Kui Chen 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2020年第8期1083-1099,共17页
To investigate the interaction mechanism between 95 Cr saw-wire steel and different refractories,we conducted laboratory experiments at 1873 K.Five crucible materials(SiO2,Al2 O3,MgO·Al2 O3,MgO,and MgO-CaO)were u... To investigate the interaction mechanism between 95 Cr saw-wire steel and different refractories,we conducted laboratory experiments at 1873 K.Five crucible materials(SiO2,Al2 O3,MgO·Al2 O3,MgO,and MgO-CaO)were used.The results indicate that SiO2,Al2 O3,and MgO·Al2 O3 are not suitable for smelting low-oxygen,low-[Al]s 95 Cr saw-wire steel,mainly because they react with the elements in the molten steel and pollute the steel samples.By contrast,MgO-CaO is an ideal choice to produce 95 Cr saw-wire steel.It offers three advantages:(ⅰ)It does not decompose by itself at the steelmaking temperature of 1873 K because it exhibits good thermal stability;(ⅱ)[C],[Si],and[Mn]in molten steel cannot react with it to increase the[O]content;and(ⅲ)it not only desulfurizes and dephosphorizes but also removes Al2 O3 inclusions from the steel simultaneously.As a result,the contents of the main elements([C],[Si],[Mn],[Cr],N,T.O(total oxygen))in the steel are not affected and the content of impurity elements([Al]s,P,and S)can be perfectly controlled within the target range.Furthermore,the number and size of inclusions in the steel samples decrease sharply when the MgO-CaO crucible is used. 展开更多
关键词 nonmetallic inclusions 95Cr saw-wire steel crucible material MgO–CaO refractory
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Development of a fine-resolution atmosphere-wave-ocean coupled forecasting model for the South China Sea and its adjacent seas 被引量:3
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作者 Junchuan sun Zexun Wei +9 位作者 Tengfei Xu meng sun Kun Liu Yongzeng Yang Li Chen Hong Zhao Xunqiang Yin Weizhong Feng Zhiyuan Zhang Yonggang Wang 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2019年第4期154-166,共13页
A 72-h fine-resolution atmosphere-wave-ocean coupled forecasting system was developed for the South China Sea and its adjacent seas. The forecasting model domain covers from from 15°S to 45°N in latitude and... A 72-h fine-resolution atmosphere-wave-ocean coupled forecasting system was developed for the South China Sea and its adjacent seas. The forecasting model domain covers from from 15°S to 45°N in latitude and 99°E to135°E in longitude including the Bohai Sea, the Yellow Sea, the East China Sea, the South China Sea and the Indonesian seas. To get precise initial conditions for the coupled forecasting model, the forecasting system conducts a 24-h hindcast simulation with data assimilation before forecasting. The Ensemble Adjustment Kalman Filter(EAKF) data assimilation method was adopted for the wave model MASNUM with assimilating Jason-2 significant wave height(SWH) data. The EAKF data assimilation method was also introduced to the ROMS model with assimilating sea surface temperature(SST), mean absolute dynamic topography(MADT) and Argo profiles data. To improve simulation of the structure of temperature and salinity, the vertical mixing scheme of the ocean model was improved by considering the surface wave induced vertical mixing and internal wave induced vertical mixing. The wave and current models were integrated from January 2014 to October 2015 driven by the ECMWF reanalysis 6 hourly mean dataset with data assimilation. Then the coupled atmosphere-wave-ocean forecasting system was carried out 14 months operational running since November 2015. The forecasting outputs include atmospheric forecast products, wave forecast products and ocean forecast products. A series of observation data are used to evaluate the coupled forecasting results, including the wind, SHW, ocean temperature and velocity.The forecasting results are in good agreement with observation data. The prediction practice for more than one year indicates that the coupled forecasting system performs stably and predict relatively accurate, which can support the shipping safety, the fisheries and the oil exploitation. 展开更多
关键词 South China Sea COAWST MODEL MASNUM MODEL atmosphere-wave-ocean forecasting system data ASSIMILATION
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Dental stem cell-derived extracellular vesicles transfer miR-330-5p to treat traumatic brain injury by regulating microglia polarization 被引量:1
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作者 Ye Li meng sun +4 位作者 Xinxin Wang Xiaoyu Cao Na Li Dandan Pei Ang Li 《International Journal of Oral Science》 SCIE CAS CSCD 2022年第4期461-469,共9页
Traumatic brain injury(TBI)contributes to the key causative elements of neurological deficits.However,no effective therapeutics have been developed yet.In our previous work,extracellular vesicles(EVs)secreted by stem ... Traumatic brain injury(TBI)contributes to the key causative elements of neurological deficits.However,no effective therapeutics have been developed yet.In our previous work,extracellular vesicles(EVs)secreted by stem cells from human exfoliated deciduous teeth(SHED)offered new insights as potential strategies for functional recovery of TBI.The current study aims to elucidate the mechanism of action,providing novel therapeutic targets for future clinical interventions.With the mi RNA array performed and Real-time PCR validated,we revealed the crucial function of mi R-330-5p transferred by SHED-derived EVs(SHED-EVs)in regulating microglia,the critical immune modulator in central nervous system.Mi R-330-5p targeted Ehmt2 and mediated the transcription of CXCL14 to promote M2 microglia polarization and inhibit M1 polarization.Identified in our in vivo data,SHED-EVs and their effector mi R-330-5p alleviated the secretion of inflammatory cytokines and resumed the motor functional recovery of TBI rats.In summary,by transferring mi R-330-5p,SHED-EVs favored anti-inflammatory microglia polarization through Ehmt2 mediated CXCL14transcription in treating traumatic brain injury. 展开更多
关键词 injury TRANSFERRED RESUME
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Fabrication and Wettability of ZnO Nanorod Array
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作者 meng sun Yi Du +3 位作者 Weichang Hao Huaizhe Xu Youxing Yu Tianmin Wang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2009年第1期53-57,共5页
ZnO nanorod arrays were prepared in an open system by using a simple aqueous solution method. Spindlelike, wimble-like, tower-like and hexagonal rod-like ZnO rods were obtained under different conditions. ZnO nanorod ... ZnO nanorod arrays were prepared in an open system by using a simple aqueous solution method. Spindlelike, wimble-like, tower-like and hexagonal rod-like ZnO rods were obtained under different conditions. ZnO nanorod arrays with different morphology and size were studied by X-ray diffraction (XRD), scanning electron microscopy (SEM), and contact angle measurement (CAM). The size of ordered zinc oxide rods can be controlled by temperature of water bath, because this temperature can influences growing speeds in different crystal directions. Some additives, such as urea and thiourea, were introduced into reaction solution to improve quality of arrays. Surface character of ZnO nanorod arrays can be changed from hydrophilic to hydrophobic, which was proved to be dependence on size of air grooves on surface. 展开更多
关键词 ZNO Nanorod array WETTABILITY HYDROPHILIC HYDROPHOBIC
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