Non-flammable long chain phosphate ester based electrolyte via competitive solventized structures for high-performance lithium metal batteries

Safety remains a persistent challenge for high-energy-density lithium metal batteries(LMBs).The development of safe and non-flammable electrolytes is especially important in harsh conditions such as high temperatures.Herein,a flame-retardant,low-cost and thermally stable long chain phosphate ester based(tributyl phosphate,TBP)electrolyte is reported,which can effectively enhance the cycling stability of highly loaded high-nickel LMBs with high safety through co-solvation strategy.The interfacial compatibility between TBP and electrode is effectively improved using a short-chain ether(glycol dimethyl ether,DME),and a specially competitive solvation structure is further constructed using lithium borate difluorooxalate(LiDFOB)to form the stable and inorganic-rich electrode interphases.Benefiting from the presence of the cathode electrolyte interphase(CEI)and solid electrolyte interphase(SEI)enriched with LiF and Li_(x)PO_(y)F_(z),the electrolyte demonstrates excellent cycling stability assembled using a 50μm lithium foil anode in combination with a high loading NMC811(15.4 mg cm^(-2))cathode,with 88%capacity retention after 120 cycles.Furthermore,the electrolyte exhibits excellent high-temperature characteristics when used in a 1-Ah pouch cell(N/P=0.26),and higher thermal runaway temperature(238℃)in the ARC(accelerating rate calorimeter)demonstrating high safety.This novel electrolyte adopts long-chain phosphate as the main solvent for the first time,and would provide a new idea for the development of extremely high safety and high-temperature electrolytes.

Modeling,analysis,and simulation of X-shape quasi-zero-stiffness-roller vibration isolators

Existing quasi-zero stiffness(QZS)isolators are reviewed.In terms of their advantages,a novel X-shape QZS isolator combined with the cam-roller-spring mechanism(CRSM)is proposed.Different from the existing X-shape isolators,oblique springs are used to enhance the negative stiffness of the system.Meanwhile,the CRSM is used to eliminate the gravity of the loading mass,while the X-shape structure leaves its static position.The existing QZS isolators are demonstrated and classified according to their nonlinearity mechanisms and classical shapes.It is shown that the oblique spring can realize negative stiffness based on the simplest mechanism.The X-shape has a strong capacity of loading mass,while the CRSM can achieve a designed restoring force at any position.The proposed isolator combines all these advantages together.Based on the harmonic balance method(HBM)and the simulation,the displacement transmissibilities of the proposed isolator,the X-shape isolators just with oblique springs,and the X-shape isolators in the traditional form are studied.The results show that the proposed isolator has the lowest beginning isolation frequency and the smallest maximum displacement transmissibility.However,it still has some disadvantages similar to the existing QZS isolators.This means that its parameters should be designed carefully so as to avoid becoming a bistable system,in which there are two potential wells in the potential energy curve and thus the isolation performance will be worsened.

Effect of Social Skill Training on Social Function in Patients with Schizophrenia

Objective:To explore the effect of Social Skills Training(SST)on the social function of inpatients with schizophrenia.Methods:A total of 40 patients with schizophrenia(20 in the intervention group and 20 in the control group)were selected from a psychiatric hospital in Shanghai for 10 times(once a week)of social skills training.The control group was treated with routine hospitalization(drug therapy and routine hospitalization nursing)for 10 weeks.Social Disability Screening Schedule before and after intervention for patients enrolled in the intervention group(Social Disability Screening Schedule,SDSS and Scale of Social Function in Psychosis Inpatients,SSPI).Conclusion:The results of social skills training on SDSS and SSPI were different between the two groups,and there was no statistical value(P>0.05).Observation of patients in this group,when undergoing social skills training,SSPI score was significantly better than the control group(P<0.01)and SDSS score was significantly lower than the control group(P<0.01),the differences were statistically significant.Social skills training and social work group intervention can improve psychiatric symptoms and further enhance social function in hospitalized patients with schizophrenia.

Integrative analysis of transcriptomic and metabolomic profiles reveals new insights into the molecular foundation of fruit quality formation in Citrullus lanatus(Thunb.)Matsum.&Nakai

In this study,an integrated transcriptome and metabolome analysis was used to explore the molecular foundation of fruit quality in two parent lines of Citrullus lanatus with distinct flesh characteristics,including ‘14-1’(sweet,red,and soft)andW600'(bitter,light yellow,and firm),as well as the corresponding F,population(bitter,light yellow,and firm).Numerous differentially expressed genes(DEGs)were identified in the fruit samples:3766 DEGs for ‘14-1’vs.W600,2767 for ‘14-1’vs.F_(1),and 1178 for F_(1) vs.‘W600’at the transition stage;and 4221 for ‘14-1’vs.W6002447 for ‘14-1’vs.F,and 446 for F,vs.‘W600’at the maturity stage.Weighted gene co-expression network analysis(WGCNA)revealed that a gene module including 1111 DEGs was closely associated with flesh taste and color,and another gene module including 1575 DEGs contributed significantly to flesh texture.The metabolomic results showed that there were 447 differential metabolites(DMs)for ‘14-1’vs.‘W600’fruits,394 for ‘14-1’vs.F,and 298 for F,vs.‘W600’at the maturity stage.Combining WGNCA and metabolomic results,several DEGs and DMs were further identified as hub players in fruitqualityformation:6DEGs with 4DMs for flesh sweetness;6DEGs with 13DMs forbitterness;9DEGs with 10 DMs for flesh color;and 9 DEGs with 4 DMs for flesh texture.Altogether,these observations not only expand our knowledge of the molecular basis of fruit quality in watermelon,but also provide potential targets for future watermelon improvement.

Venous thromboembolism in children with acute lymphoblastic leukemia in China:a report from the Chinese Children’s Cancer Group-ALL-2015

Venous thromboembolism(VTE)is a complication in children with acute lymphoblastic leukemia(ALL).The Chinese Children’s Cancer Group-ALL-2015 protocol was carried out in China,and epidemiology,clinical characteristics,and risk factors associated with VTE were analyzed.We collected data on VTE in a multiinstitutional clinical study of 7640 patients with ALL diagnosed in 20 hospitals from January 2015 to December 2019.First,VTE occurred in 159(2.08%)patients,including 90(56.6%)during induction therapy and 108(67.92%)in the upper extremities.T-ALL had a 1.74-fold increased risk of VTE(95%CI 1.08–2.8,P=0.022).Septicemia,as an adverse event of ALL treatment,can significantly promote the occurrence of VTE(P<0.001).Catheter-related thrombosis(CRT)accounted for 75.47%(n=120);and,symptomatic VTE,58.49%(n=93),which was more common in patients aged 12–18 years(P=0.023),non-CRT patients(P<0.001),or patients with cerebral thrombosis(P<0.001).Of the patients with VTE treated with anticoagulation therapy(n=147),4.08%(n=6)had bleeding.The VTE recurrence rate was 5.03%(n=8).Patients with VTE treated by non-ultrasoundguided venous cannulation(P=0.02),with residual thrombus(P=0.006),or with short anticoagulation period(P=0.026)had high recurrence rates.Thus,preventing repeated venous puncture and appropriately prolonged anticoagulation time can reduce the risk of VTE recurrence.