Michael addition of indole and pyrrole to a variety of α, β-unsaturated ketones was efficiently promoted by a catalytic amount of GaCl3 in aqueous media to afford the corresponding products in good to excellent yields.
A Yb（OTf）3-catalyzed approach for the synthesis of pyrroles under solvent-free conditions was achieved, which could afford the desired products with yields ranged from moderate to excellent.
基金support by the Natural Science Foundation of Zhejiang Province(No.Y4051137,Y405015 and Y4080177)
文摘Michael addition of indole and pyrrole to a variety of α, β-unsaturated ketones was efficiently promoted by a catalytic amount of GaCl3 in aqueous media to afford the corresponding products in good to excellent yields.
基金the National Key Technology R&D Program(No.2007BAI34B00)the National Natural Science Foundation of China(No.20876147 and 20676123)the Natural Science Foundation of Zhejiang Province(No.Y4080107) for financial support.
文摘A Yb（OTf）3-catalyzed approach for the synthesis of pyrroles under solvent-free conditions was achieved, which could afford the desired products with yields ranged from moderate to excellent.
