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Influence of humanistic care-based operating room nursing on safety,recovery,and satisfaction after radical surgery for colorectal carcinoma 被引量:1
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作者 Xian-Pu Wang min niu 《World Journal of Clinical Cases》 SCIE 2024年第24期5483-5491,共9页
BACKGROUND Radical surgery is a preferred treatment for colorectal carcinoma,wherein nursing intervention is essential for postoperative recovery and prevention of complications.Recently,the application of humanistic ... BACKGROUND Radical surgery is a preferred treatment for colorectal carcinoma,wherein nursing intervention is essential for postoperative recovery and prevention of complications.Recently,the application of humanistic care in medical care has attracted attention.Humanistic care emphasizes comprehensive care,with importance attached to patients’physical needs as well as psychological and emotional support to provide more humane and personalized care services.However,no clinical reports have examined the use of humanistic care in patients undergoing radical surgery for colorectal carcinoma.AIM To investigate the influence of humanistic care-based operating room nursing on the safety,postoperative recovery,and nursing satisfaction of patients who have undergone radical surgery for colorectal carcinoma.METHODS In total,120 patients with rectal cancer who underwent surgery in Zhongnan Hospital of Wuhan University between August 2023 and March 2024 were selected and grouped based on the nursing methods employed.Of these patients,55 were treated with routine nursing intervention(control group)and 65 were provided humanistic care-based operating room nursing(research group).The patients’vital signs were recorded,including systolic/diastolic blood pressure(SBP/DBP)and heart beats per minute(BPM),as well as serum stress indices,including norepinephrine(NE),adrenal hormone(AD),and cortisol(Cor).Postoperative recovery and complications were also recorded.Patients’negative emotions,life hope,and nursing satisfaction were evaluated using the Self-rating Depression/Anxiety Scale(SDS/SAS),Herth Hope Index(HHI),and self-deve-loped nursing satisfaction questionnaire,respectively.RESULTS During emergence from anesthesia,SBP,DBP,and BPM levels were found to be lower in the research group than those in the control group,also serum Cor,AD,and NE levels were lower.In addition,the research group had shorter operative,awakening,anal exhaust,first postoperative ambulation,drainage tube removal,intestinal recovery,and hospital times.The total complication rate and the SDS and SAS scores were lower in the research group than those in the control group.The HHI and nursing satisfaction scores were higher in the research group.CONCLUSION Humanistic care-based operating room nursing can mitigate physiological stress responses,reduce postoperative complications,promote postoperative recovery,relieve adverse psychological emotions,and enhance life hope and nursing satisfaction in patients undergoing radical surgery for colorectal carcinoma,which can be popularized in clinical practice. 展开更多
关键词 Humanistic care NURSING Radical surgery for rectal carcinoma Stress response
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双醋瑞因联合玻璃酸钠治疗膝骨关节炎的疗效分析 被引量:11
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作者 牛敏 杨西超 +2 位作者 米娜瓦尔·卡尔曼 王文涛 李英 《中国现代医学杂志》 CAS 北大核心 2021年第4期21-25,共5页
目的探讨双醋瑞因联合玻璃酸钠治疗膝骨关节炎的疗效及其对细胞因子和Toll样受体4(TLR4)/核因子κB(NF-κB)信号通路的影响。方法选取2016年6月—2019年5月在西安市红会医院和西京医院就诊的膝骨关节炎患者100例,随机分为观察组和对照组... 目的探讨双醋瑞因联合玻璃酸钠治疗膝骨关节炎的疗效及其对细胞因子和Toll样受体4(TLR4)/核因子κB(NF-κB)信号通路的影响。方法选取2016年6月—2019年5月在西安市红会医院和西京医院就诊的膝骨关节炎患者100例,随机分为观察组和对照组,每组50例。对照组患者给予玻璃酸钠关节腔注射液,1次/周;观察组患者在对照组基础上口服双醋瑞因胶囊,50 mg/次,2次/d。两组疗程均为5周。比较两组疗效和治疗前后Lysholm膝关节功能评分和视觉模拟评分(VAS)、血清细胞因子[白细胞介素-1β(IL-1β)、IL-6和肿瘤坏死因子-α(TNF-α)],以及关节滑膜中TLR4和NF-κB蛋白相对表达量。结果两组患者总有效率比较,差异无统计学意义(P>0.05)。观察组治疗前后Lysholm膝关节功能评分和VAS评分的差值高于对照组(P<0.05)。观察组治疗前后血清IL-1β、IL-6、TNF-α的差值高于对照组(P<0.05)。观察组治疗前后关节滑膜中TLR4和NF-κB蛋白相对表达量的差值高于对照组(P<0.05)。结论双醋瑞因联合玻璃酸钠治疗膝骨关节炎患者效果良好,其作用机制可能与降低细胞因子IL-1β、IL-6、TNF-α水平及下调TLR4/NF-κB表达有关。 展开更多
关键词 骨关节炎 双醋瑞因 玻璃酸钠 疗效比较研究 细胞因子 TOLL样受体4 核因子ΚB
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Research on variation and significance of immune cells, inflammatory factors and coagulation functions in patients with pulmonary tuberculosis 被引量:1
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作者 Wei-Lan Ma Fang Han min niu 《Journal of Hainan Medical University》 2017年第1期93-96,共4页
Objective:To investigate variation of T lymphocyte subsets, inflammatory factors and coagulation functional indexes at different stages for patients with pulmonary tuberculosis and significance of discussion and treat... Objective:To investigate variation of T lymphocyte subsets, inflammatory factors and coagulation functional indexes at different stages for patients with pulmonary tuberculosis and significance of discussion and treatment on mechanism of pulmonary tuberculosis. Methods:48 cases of patients with pulmonary tuberculosis at progressive stage treated in our hospital were selected as the progression group, and 50 cases of patients with pulmonary tuberculosis at remission stage were selected as the remission group. Meanwhile, 48 cases of healthy population in our hospital were selected as the control group. Variations and significances of T lymphocyte subsets (CD3+, CD4+, CD8+ and CD4+/CD8+), inflammatory factors [interleukin-2 (IL-2), interleukin-10 (IL-10), interferon-γ (IFN-γ) and tumor necrosis factor-α(TNF-α)] and coagulation function [Fg (fibrinogen), TT (thrombin time), PLT (platelet) and D-D (D-dimer)] were analyzed.Results: Coagulation function (Fg, TT, PLT and D-D), T lymphocyte subsets CD8+ and inflammatory factors (IL-2, IL-10 and TNF-α) in patients with pulmonary tuberculosis in progression group were significantly higher than in healthy population of control group (P<0.05). T lymphocyte subsets (CD3+, CD4+ andCD4+/CD8+) and IFN-γ were significantly lower than in healthy population of control group (P<0.05). Coagulation function (Fg, TT, PLT and D-D), T lymphocyte subsets CD8+ and inflammatory factors (IL-2, IL-10 and TNF-α) in patients with pulmonary tuberculosis in remission group were significantly lower than in patients of progression group (P<0.05), but significantly higher than in healthy population of control group (P<0.05). T lymphocyte subsets (CD3+, CD4+ and CD4+/CD8+) and IFN-γ in patients with pulmonary tuberculosis in remission group were significantly higher than in patients of progression group (P<0.05), but significantly lower than in healthy population of control group (P<0.05).Conclusions:Significant variations appeared on T lymphocyte subsets, inflammatory factors and coagulation functional indexes at different stages for patients with pulmonary tuberculosis, which had important significance on discussion and treatment of pulmonary tuberculosis mechanism. 展开更多
关键词 Pulmonary TUBERCULOSIS T LYMPHOCYTE SUBSETS Inflammatory factors COAGULATION function VARIATION and SIGNIFICANCE
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Bifunctional SiC/Si_(3)N_(4) aerogel for highly efficient electromagnetic wave absorption and thermal insulation 被引量:2
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作者 Lei WANG Zhixin CAI +4 位作者 Lei SU min niu Kang PENG Lei ZHUANG Hongjie WANG 《Journal of Advanced Ceramics》 SCIE EI CAS CSCD 2023年第2期309-320,共12页
SiC ceramics are attractive electromagnetic(EM)absorption materials for the application in harsh environment because of their low density,good dielectric tunable performance,and chemical stability.However,the performa... SiC ceramics are attractive electromagnetic(EM)absorption materials for the application in harsh environment because of their low density,good dielectric tunable performance,and chemical stability.However,the performance of current SiC-based materials to absorb EM wave is generally unsatisfactory due to poor impedance matching.Herein,we report ultralight SiC/Si3N4 composite aerogels(~15 mg·cm^(−3))consisting of numerous interweaving SiC nanowires and Si3N4 nanoribbons.Aerogels were prepared via siloxane pyrolysis and chemical vapor reaction through the template method.The optimal aerogel exhibits excellent EM wave absorption properties with a strong reflection loss(RL,−48.6 dB)and a wide effective absorption band(EAB,7.4 GHz)at a thickness of 2 mm,attributed to good impedance matching and multi attenuation mechanisms of waves within the unique network structure.In addition,the aerogel exhibits high thermal stability in air until 1000℃and excellent thermal insulation performance(0.030 W·m^(−1)·K^(−1)).These superior performances make the SiC/Si_(3)N_(4) composite aerogel promising to become a new generation of absorption material served under extreme conditions. 展开更多
关键词 bicontinuous network SiC nanowires impedance matching electromagnetic(EM)wave absorption extreme conditions
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Resilient Si_(3)N_(4)@SiO_(2)nanowire aerogels for high-temperature electromagnetic wave transparency and thermal insulation 被引量:1
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作者 Wei Zhang Lei Su +5 位作者 De Lu Kang Peng min niu Lei Zhuang Jian Feng Hongjie Wang 《Journal of Advanced Ceramics》 SCIE EI CAS CSCD 2023年第11期2112-2122,共11页
With the development of aerospace technology,the Mach number of aircraft continues to increase,which puts forward higher performance requirements for high-temperature wave-transparent materials.Silicon nitrides have e... With the development of aerospace technology,the Mach number of aircraft continues to increase,which puts forward higher performance requirements for high-temperature wave-transparent materials.Silicon nitrides have excellent mechanical properties,high-temperature stability,and oxidation resistance,but their brittleness and high dielectric constant impede their practical applications.Herein,by employing a template-assisted precursor pyrolysis method,we prepared a class of Si_(3)N_(4)@SiO_(2)nanowire aerogels(Si_(3)N_(4)@SiO_(2)NWAGs)that are assembled by Si_(3)N_(4)@SiO_(2)nanowires with diameters ranging from 386 to 631 nm.Si_(3)N_(4)@SiO_(2)NWAGs have low density of 12–31 mg∙cm^(−3),specific surface area of 4.13 m^(2)∙g^(−1),and average pore size of 68.9μm.Mechanical properties characterization shows that the aerogels exhibit reversible compressibility from 60%compressive strain and good fatigue resistance even when being compressed 100 times at set strain of 20%.The aerogels also show good thermal insulation performance(0.032 W·m^(−1)∙K^(−1) at room temperature),ablation resistance(butane blow torch),and high-temperature stability(maximum service temperature in air over 1200℃).The dielectric constant and loss of the aerogels are 1.02–1.06 and 4.3×10^(−5)–1.4×10^(−3) at room temperature,respectively.The combination of good mechanical,thermal,and dielectric properties makes Si_(3)N_(4)@SiO_(2)NWAGs promising ultralight wave-transparent and thermally insulating materials for applications at high temperatures. 展开更多
关键词 electromagnetic wave transparency resilient ceramic aerogels high-temperature stability fire resistance high-temperature resistance
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The origin and development of pragmatics as a study of meaning:semiotic perspective
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作者 min niu 《Language and Semiotic Studies》 2023年第1期54-78,共25页
Pragmatics has grown into a flourishing independent academic discipline.Undefined and unsolved are,nevertheless,such confusing and controversial concerns in its evolution as research boundaries and uncertain definitio... Pragmatics has grown into a flourishing independent academic discipline.Undefined and unsolved are,nevertheless,such confusing and controversial concerns in its evolution as research boundaries and uncertain definition.Some academics view Austin's Speech Act Theory to be the birth of pragmatics,which certainly confines pragmatics to the field of linguistics and hence limits its study scope.This assertion is incongruous with Morris'primary objective of proposing the word pragmatics from the standpoint of semiotics,inspired by Peirce.This research intends to investigate pragmatics from the perspective of linguistic philosophy and semiotics and argues that pragmatics derives and develops from Peirce's pragmatist semiotics and Morris'behavioral semiotics.Pragmatics is the exertion of the"interpretant"in Pierce's Semiotics.Clearly,it is one of the three branches of Morris's semiotics that investigates the relationship between signs and sign users.The meaning of signs is derived from the interpretation of sign users.Pierce's pragmatism or pragmaticism is the intellectual foundation of pragmatics.As its research objective,it focuses on the relationship between meaning and context,i.e.,the llocutionary meaning not covered by the study of semantics.Its primary methodology is based on logical reasoning. 展开更多
关键词 interpretant MEANING pragmaticism PRAGMATICS SEMIOTICS
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铁载体毒力基因entB对碳青霉烯类耐药肺炎克雷伯菌毒力的影响 被引量:5
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作者 韩睿辉 牛敏 +2 位作者 刘淑敏 毕建蝶 杜艳 《中华检验医学杂志》 CAS CSCD 北大核心 2022年第6期642-648,共7页
目的明确铁载体毒力基因entB对碳青霉烯类耐药肺炎克雷伯菌(CRKP)毒力的影响。方法从昆明医科大学第一附属医院收集到的30株CRKP菌株中筛选出CRKP-27作为实验菌株,规律间隔成簇短回文重复序列(CRISPR)-Cas9基因敲除技术构建entB基因缺... 目的明确铁载体毒力基因entB对碳青霉烯类耐药肺炎克雷伯菌(CRKP)毒力的影响。方法从昆明医科大学第一附属医院收集到的30株CRKP菌株中筛选出CRKP-27作为实验菌株,规律间隔成簇短回文重复序列(CRISPR)-Cas9基因敲除技术构建entB基因缺失株ΔentB、回补株C-ΔentB,并通过PCR验证敲除及回补是否成功。观察CRKP-27、ΔentB、C-ΔentB菌株的菌落形态并进行拉丝试验,初步了解entB对CRKP菌落形态和毒力表型的影响。绘制菌株生长曲线,测定entB对CRKP菌株生长的影响。铬天青S(CAS)检测液对菌株产铁载体能力进行定量检测。建立小鼠腹腔感染模型,观察小鼠生存率直观了解entB基因对CRKP毒力的影响。计量资料均采用平均数±标准差表示,服从正态分布的数据采用方差分析进行组间比较,不服从正态分布的数据采用Kruskal-Wallis秩和检验。小鼠生存分析用Log-Rank检验进行比较。P<0.05表示差异具有统计学意义。结果PCR结果显示缺失株和回补株构建成功。entB基因对CRKP的菌落形态、荚膜和毒力表型无明显影响。ΔentB组的生长速度明显快于CRKP-27组(P=0.008)和C-ΔentB组(P=0.001),说明entB基因削弱了CRKP菌株的生长能力。entB组与CRKP-27组(P=0.001)和C-ΔentB组(P=0.001)相比铁载体产量明显下降,分别下降11.7393%和11.9642%,说明entB基因显著增加了CRKP产铁载体能力。动物实验中,与CRKP-27组(P=0.023)和C-ΔentB组(P=0.024)相比,ΔentB组小鼠生存率明显增高,说明entB基因增加了CRKP菌株的毒力。结论铁载体毒力基因entB明显减弱了菌株的生长能力,但使CRKP产铁载体能力、毒力明显增强。 展开更多
关键词 克雷伯菌 肺炎 碳青霉烯类耐药 铁载体 毒力基因
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A review on the emerging resilient and multifunctional ceramic aerogels 被引量:3
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作者 Lei Su min niu +3 位作者 De Lu Zhixin Cai mingzhu Li Hongjie Wang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2021年第16期1-13,共13页
Ceramic aerogels are attractive for their low density,high porosity,large surface area as well as various applications in areas of thermal insulation,catalysis,filtration,and lightweight structural materials.Conventio... Ceramic aerogels are attractive for their low density,high porosity,large surface area as well as various applications in areas of thermal insulation,catalysis,filtration,and lightweight structural materials.Conventional ceramic aerogels are usually assembled by oxides nanoparticles.Due to the inefficient necklike connections between the nanoparticles and the volume shrinkage at elevated temperatures,ceramic aerogels fail easily caused by the brittleness and high-temperature structural collapse.To overcome these drawbacks,a class of resilient ceramic aerogels with highly porous architectures that are composed of one-or two-dimensional nanostructures has been prepared.Benefiting from the unique microstructures and/or the high-temperature stability of their building blocks,these aerogels exhibit reversible compressibility,high-temperature stability,thermal insulation,and various functions.In this review,we introduced the preparation methods,microstructures,mechanical properties,high-temperature stability,thermal insulation and various functions of these resilient ceramic aerogels.We have also discussed the relationships between their microstructures and properties,including mechanical properties and thermal insulation performance.Finally,perspectives for the further development of resilient ceramic aerogels are presented. 展开更多
关键词 Ceramic aerogel Reversible compressibility High-temperature stability Thermal insulation MULTIFUNCTION
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High-entropy Sm_(2)B_(2)O_(7)(B=Ti,Zr,Sn,Hf,Y,Yb,Nb,and Ta) oxides with highly disordered B-site cations for ultralow thermal conductivity 被引量:1
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作者 Liang Xu Lei Su +6 位作者 Hongjie Wang Hongfei Gao Pengfei Guo min niu Kang Peng Lei Zhuang Zhiwei Dai 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2022年第24期182-189,共8页
Materials with ultralow thermal conductivity and good thermal stability are of great interest in numerous applications such as energy storage and conversion devices,and thermal insulation components.In this work,a fam... Materials with ultralow thermal conductivity and good thermal stability are of great interest in numerous applications such as energy storage and conversion devices,and thermal insulation components.In this work,a family of high-entropy Sm_(2)B_(2)O_(7)(B=Ti,Zr,Sn,Hf,Y,Yb,Nb,and Ta) oxides with highly disordered cations on the B-site has been synthesized by introducing large atomic-size mismatch,mass and charge disorder.Through tuning the composition,the high-entropy Sm_(2)B_(2)O_(7) oxides can be engineered from pyrochlore to fluorite structure,accompanied with an order-disorder transition.The pyrochlore Sm_(2)(Nb_(0.2)Sn_(0.2)Ti_(0.2)Y_(0.2)Zr_(0.2))_(2)O_(7) and fluorite Sm_(2)(Nb_(0.2)Ta_(0.2)Y_(0.2)Yb_(0.2)Zr_(0.2))_(2)O_(7) exhibit low thermal conductivities of 1.35 W·m^(-1)·K^(-1) and 1.23 W·m^(-1)·K^(-1),respectively,indicating their good thermal insulation.In addition,the high-entropy fluorite Sm_(2)(Nb_(0.2)Ta_(0.2)Y_(0.2)Yb_(0.2)Zr_(0.2))_(2)O_(7) also shows average thermal expansion coefficient of 10.2 × 10^(-6)℃^(-1) and high-temperature stability even after thermal exposure at 1600 °C in air for 30 h.These results indicate that the high-entropy Sm_(2)B_(2)O_(7)(B=Ti,Zr,Sn,Hf,Y,Yb,Nb,and Ta) can be promising candidates for thermal barrier coatings and thermally insulators. 展开更多
关键词 High-entropy oxides Atomic sizes mismatch Mass and charge disorder Thermal conductivity Thermal barrier coatings materials
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The Hausdorff Dimension of Sections 被引量:1
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作者 min niu Lifeng XI 《Chinese Annals of Mathematics,Series B》 SCIE CSCD 2007年第2期187-194,共8页
The notion of finite-type open set condition is defined to calculate the Hausdorff dimensions of the sections of some self-similar sets, such as the dimension of intersection of the Koch curve and the line x=α with ... The notion of finite-type open set condition is defined to calculate the Hausdorff dimensions of the sections of some self-similar sets, such as the dimension of intersection of the Koch curve and the line x=α with α∈ Q. 展开更多
关键词 Hausdorff dimension Self-similar set SECTION Open set condition
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