Highly Integrated Perovskite Solar Cells-Based Photorechargeable System with Excellent Photoelectric Conversion and Energy Storage Ability

Perovskite solar cells have emerged as a promising technology for renewable energy generation.However,the successful integration of perovskite solar cells with energy storage devices to establish high-efficiency and long-term stable photorechargeable systems remains a persistent challenge.Issues such as electrical mismatch and restricted integration levels contribute to elevated internal resistance,leading to suboptimal overall efficiency(η_(overall))within photorechargeable systems.Additionally,the compatibility of perovskite solar cells with electrolytes from energy storage devices poses another significant concern regarding their stability.To address these limitations,we demonstrate a highly integrated photorechargeable system that combines perovskite solar cells with a solid-state zinc-ion hybrid capacitor using a streamlined process.Our study employs a novel ultraviolet-cured ionogel electrolyte to prevent moisture-induced degradation of the perovskite layer in integrated photorechargeable system,enabling perovskite solar cells to achieve maximum power conversion efficiencies and facilitating the monolithic design of the system with minimal energy loss.By precisely matching voltages between the two modules and leveraging the superior energy storage efficiency,our integrated photorechargeable system achieves a remarkableηoverall of 10.01%while maintaining excellent cycling stability.This innovative design and the comprehensive investigations of the dynamic photocharging process in monolithic systems,not only offer a reliable and enduring power source but also provide guidelines for future development of self-power off-grid electronics.

Analysis of application range of simplified models for field to thermo-field to thermionic emission processes from the cathode

Electron emission plays a dominant role in plasma-cathode interactions and is a key factor in many plasma phenomena and industrial applications.It is necessary to illustrate the various electron emission mechanisms and the corresponding applicable description models to evaluate their impacts on discharge properties.In this study,detailed expressions of the simplified formulas valid for field emission to thermo-field emission to thermionic emission typically used in the numerical simulation are proposed,and the corresponding application ranges are determined in the framework of the Murphy-Good theory,which is commonly regarded as the general model and to be accurate in the full range of conditions of the validity of the theory.Dimensionless parameterization was used to evaluate the emission current density of the Murphy-Good formula,and a deviation factor was defined to obtain the application ranges for different work functions(2.5‒5 eV),cathode temperatures(300‒6000 K),and emitted electric fields(10^(5) to 10^(10) V·m^(-1)).The deviation factor was shown to be a nonmonotonic function of the three parameters.A comparative study of particle number densities in atmospheric gas discharge with a tungsten cathode was performed based on the one-dimensional implicit particle-in-cell(PIC)with the Monte Carlo collision(MCC)method according to the aforementioned application ranges.It was found that small differences in emission current density can lead to variations in the distributions of particle number density due to changes in the collisional environment.This study provides a theoretical basis for selecting emission models for subsequent numerical simulations.

Towards privacy-preserving and efficient word vector learning for lightweight IoT devices

Nowadays,Internet of Things(IoT)is widely deployed and brings great opportunities to change people's daily life.To realize more effective human-computer interaction in the IoT applications,the Question Answering(QA)systems implanted in the IoT services are supposed to improve the ability to understand natural language.Therefore,the distributed representation of words,which contains more semantic or syntactic information,has been playing a more and more important role in the QA systems.However,learning high-quality distributed word vectors requires lots of storage and computing resources,hence it cannot be deployed on the resource-constrained IoT devices.It is a good choice to outsource the data and computation to the cloud servers.Nevertheless,it could cause privacy risks to directly upload private data to the untrusted cloud.Therefore,realizing the word vector learning process over untrusted cloud servers without privacy leakage is an urgent and challenging task.In this paper,we present a novel efficient word vector learning scheme over encrypted data.We first design a series of arithmetic computation protocols.Then we use two non-colluding cloud servers to implement high-quality word vectors learning over encrypted data.The proposed scheme allows us to perform training word vectors on the remote cloud servers while protecting privacy.Security analysis and experiments over real data sets demonstrate that our scheme is more secure and efficient than existing privacy-preserving word vector learning schemes.

Reconfigurable and polarization-dependent optical filtering for transflective full-color generation utilizing low-loss phase-change materials

All-dielectric metasurface, which features low optical absorptance and high resolution, is becoming a promising candidate for full-color generation. However, the optical response of current metamaterials is fixed and lacks active tuning. In this work, we demonstrate a reconfigurable and polarization-dependent active color generation technique by incorporating low-loss phase change materials(PCMs) and CaF_2 all-dielectric substrate. Based on the strong Mie resonance effect and low optical absorption structure, a transflective, full-color with high color purity and gamut value is achieved. The spectrum can be dynamically manipulated by changing either the polarization of incident light or the PCM state. High transmittance and reflectance can be simultaneously achieved by using low-loss PCMs and substrate. The novel active metasurfaces can bring new inspiration in the areas of optical encryption, anti-counterfeiting, and display technologies.

Relationship between self-propelled velocity and Brownian motion for spherical and ellipsoid particles

The Brownian motion of spherical and ellipsoidal self-propelled particles was simulated without considering the effect of inertia and using the Langevin equation and the diffusion coefficient of ellipsoidal particles derived by Perrin.The P´eclet number(Pe)was introduced to measure the relative strengths of self-propelled and Brownian motions.We found that the motion state of spherical and ellipsoid self-propelled particles changed significantly under the influence of Brownian motion.For spherical particles,there were three primary states of motion:1)when Pe<30,the particles were still significantly affected by Brownian motion;2)when Pe>30,the self-propelled velocities of the particles were increasing;and 3)when Pe>100,the particles were completely controlled by the self-propelled velocities and the Brownian motion was suppressed.In the simulation of the ellipsoidal self-propelled particles,we found that the larger the aspect ratio of the particles,the more susceptible they were to the influence of Brownian motion.In addition,the value interval of Pe depended on the aspect ratio.Finally,we found that the directional motion ability of the ellipsoidal self-propelled particles was much weaker than that of the spherical self-propelled particles.

Simulation of charge-exchange induced NBI losses on EAST

The neutral beam injection is widely adopted in tokamaks as a key heating tool,playing a crucial role in generating burning plasmas.However,the loss of beam ions can damage the first wall and reduce the heating efficiency,resulting in failure to maintain steady-state conditions.In this work,the effect of neutral particles in the edge on fast ions generated by NBI in the Experimental Advanced Superconducting Tokamak(EAST)device is studied using the particle tracer code(PTC).The poloidal distribution of neutral particles is calculated by edge plasma simulation code SOLPS-ITER.In this simulation,four beam lines in EAST are considered:co-current tangential(co-tang),co-current perpendicular(co-perp),counter-current tangential(ctr-tang)and counter-current perpendicular(ctr-perp).It is shown that,in the absence of neutral particles,the loss fraction of ctr-injection is considerably higher than that of the co-injection.When considering the neutral particles,it is found that the ctr-perp injection demonstrates a significant variation in particles loss fraction(ranging from 18.56%to 25.42%)compared to the other three injection configurations.In terms of the loss fraction induced by neutral particles,ctr-injection exceeds co-injection,and perpendicular configuration exceeds tangential configuration.Furthermore,the difference of charge exchange ratios of three different energy(full energy,half energy,one third energy)of the four injections can be attributed to variations in the poloidal trajectories associated with each of these injections.Moreover,approximately half of fast ions which undergo neutralization directly lose to the first wall while the rest re-enter the bulk plasma and re-ionize.Except for the ctr-tang injection,the reionization ions from the other three injections exhibit effective confinement.

Research progress of tumor-associated macrophages in immune checkpoint inhibitor tolerance in colorectal cancer

The relevant mechanism of tumor-associated macrophages(TAMs)in the treatment of colorectal cancer patients with immune checkpoint inhibitors(ICIs)is discussed,and the application prospects of TAMs in reversing the treatment tolerance of ICIs are discussed to provide a reference for related studies.As a class of drugs widely used in clinical tumor immunotherapy,ICIs can act on regulatory molecules on cells that play an inhibitory role-immune checkpoints-and kill tumors in the form of an immune response by activating a variety of immune cells in the immune system.The sensitivity of patients with different types of colorectal cancer to ICI treatment varies greatly.The phenotype and function of TAMs in the colorectal cancer microenvironment are closely related to the efficacy of ICIs.ICIs can regulate the phenotypic function of TAMs,and TAMs can also affect the tolerance of colorectal cancer to ICI therapy.TAMs play an important role in ICI resistance,and making full use of this target as a therapeutic strategy is expected to improve the immunotherapy efficacy and prognosis of patients with colorectal cancer.

Design and Implementation of a High-Sensitivity Magnetic Sensing System Based on GMI Effect

A high-sensitivity magnetic sensing system based on giant magneto-impedance(GMI)effect is designed and fabricated.The system comprises a GMI sensor equipped with a gradient probe and an signal acquisition and processing module.A segmented superposition algorithm is used to increase target signal and reduce the random noise.The results show that under unshielded,room temperature conditions,the system achieves successful detection of weak magnetic fields down to 2 pT with a notable sensitivity of 1.84×10^(8)V/T(G=1000).By applying 17 overlays,the segmented superposition algorithm increases the power proportion of the target signal at 31 Hz from6.89%to 45.91%,surpassing the power proportion of the 2 Hz low-frequency interference signal.Simultaneously,it reduces the power proportion of the 20 Hz random noise.The segmented superposition process effectively cancels out certain random noise elements,leading to a reduction in their respective power proportions.This high-sensitivity magnetic sensing system features a simple structure,and is easy to operate,making it highly valuable for both practical applications and broader dissemination.

Effectiveness of colonoscopy,immune fecal occult blood testing,and risk-graded screening strategies in colorectal cancer screening

BACKGROUND Colorectal cancer(CRC)is one of the most common malignant tumors,and early screening is crucial to improving the survival rate of patients.The combination of colonoscopy and immune fecal occult blood detection has garnered significant attention as a novel method for CRC screening.Colonoscopy and fecal occult blood tests,when combined,can improve screening accuracy and early detection rates,thereby facilitating early intervention and treatment.However,certain risks and costs accompany it,making the establishment of a risk classification model crucial for accurate classification and management of screened subjects.AIM To evaluate the feasibility and effectiveness of colonoscopy,immune fecal occult blood test(FIT),and risk-graded screening strategies in CRC screening.METHODS Based on the randomized controlled trial of CRC screening in the population conducted by our hospital May 2020 to May 2023,participants who met the requirements were randomly assigned to a colonoscopy group,an FIT group,or a graded screening group at a ratio of 1:2:2(after risk assessment,the high-risk group received colonoscopy,the low-risk group received an FIT test,and the FITpositive group received colonoscopy).The three groups received CRC screening with different protocols,among which the colonoscopy group only received baseline screening,and the FIT group and the graded screening group received annual follow-up screening based on baseline screening.The primary outcome was the detection rate of advanced tumors,including CRC and advanced adenoma.The population participation rate,advanced tumor detection rate,and colonoscopy load of the three screening programs were compared.RESULTS A total of 19373 subjects who met the inclusion and exclusion criteria were enrolled,including 8082 males(41.7%)and 11291 females(58.3%).The mean age was 60.05±6.5 years.Among them,3883 patients were enrolled in the colonoscopy group,7793 in the FIT group,and 7697 in the graded screening group.Two rounds of follow-up screening were completed in the FIT group and the graded screening group.The graded screening group(89.2%)and the colonoscopy group(42.3%)had the lowest overall screening participation rates,while the FIT group had the highest(99.3%).The results of the intentional analysis showed that the detection rate of advanced tumors in the colonoscopy group was greater than that of the FIT group[2.76%vs 2.17%,odds ratio(OR)=1.30,95%confidence interval(CI):1.01-1.65,P=0.037].There was no significant difference in the detection rate of advanced tumors between the colonoscopy group and the graded screening group(2.76%vs 2.35%,OR=1.9,95%CI:0.93-1.51,P=0.156),as well as between the graded screening group and the FIT group(2.35%vs 2.17%,OR=1.09%,95%CI:0.88-1.34,P=0.440).The number of colonoscopy examinations required for each patient with advanced tumors was used as an index to evaluate the colonoscopy load during population screening.The graded screening group had the highest colonoscopy load(15.4 times),followed by the colonoscopy group(10.2 times),and the FIT group had the lowest(7.8 times).CONCLUSION A hierarchical screening strategy based on CRC risk assessment is feasible for screening for CRC in the population.It can be used as an effective supplement to traditional colonoscopy and FIT screening programs.

Ultrasomics in liver cancer: Developing a radiomics model for differentiating intrahepatic cholangiocarcinoma from hepatocellular carcinoma using contrast-enhanced ultrasound

BACKGROUND Hepatocellular carcinoma(HCC)and intrahepatic cholangiocarcinoma(ICC)represent the predominant histological types of primary liver cancer,comprising over 99%of cases.Given their differing biological behaviors,prognoses,and treatment strategies,accurately differentiating between HCC and ICC is crucial for effective clinical management.Radiomics,an emerging image processing technology,can automatically extract various quantitative image features that may elude the human eye.Reports on the application of ultrasound(US)-based radiomics methods in distinguishing HCC from ICC are limited.METHODS In our retrospective study,we included a total of 280 patients who were diagnosed with ICC(n=140)and HCC(n=140)between 1999 and 2019.These patients were divided into training(n=224)and testing(n=56)groups for analysis.US images and relevant clinical characteristics were collected.We utilized the XGBoost method to extract and select radiomics features and further employed a random forest algorithm to establish ultrasomics models.We compared the diagnostic performances of these ultrasomics models with that of radiologists.RESULTS Four distinct ultrasomics models were constructed,with the number of selected features varying between models:13 features for the US model;15 for the contrast-enhanced ultrasound(CEUS)model;13 for the combined US+CEUS model;and 21 for the US+CEUS+clinical data model.The US+CEUS+clinical data model yielded the highest area under the receiver operating characteristic curve(AUC)among all models,achieving an AUC of 0.973 in the validation cohort and 0.971 in the test cohort.This performance exceeded even the most experienced radiologist(AUC=0.964).The AUC for the US+CEUS model(training cohort AUC=0.964,test cohort AUC=0.955)was significantly higher than that of the US model alone(training cohort AUC=0.822,test cohort AUC=0.816).This finding underscored the significant benefit of incorporating CEUS information in accurately distin-guishing ICC from HCC.CONCLUSION We developed a radiomics diagnostic model based on CEUS images capable of quickly distinguishing HCC from ICC,which outperformed experienced radiologists.

模拟直流电机调速特性的双向DC/DC变换器虚拟直流电机控制策略

传统虚拟直流电机VDCM(Virtual DC Machine)控制策略未考虑直流电机转速动态调节问题,不能够在直流母线电压变化瞬间起调节作用。对此,提出一种模拟直流电机闭环调速的储能侧双向DC/DC变换器新型VDCM控制策略。对直流电机与双向DC/DC变换器在数学模型和控制策略上进行联系等效与差异剖析,模拟直流电机定转子绕组间的电磁感应作用,将直流电机动态数学模型嵌入P-U下垂控制中,使其兼备电压动态调节能力和惯性阻尼特性。对采用新型VDCM控制策略前、后的作用效果进行对比,仿真和实验结果表明该控制策略能够在提升母线电压动态调节特性的同时,增强惯性调节和阻尼效果,在负载切换或分布式发电单元输出功率波动时维持直流微电网稳定运行。

开关电容PWM DC-DC电压调节模块

介绍了一种开关电容PWM DC-DC电压调节模块,该变换器是开关电容变换器和PWM变换器的结合,具有如下优点:①开关管的零电压开关(Zero-Voltage-Switching,ZVS);②运用自耦变压器实现同步整流管(Synchronous Rectifier,SR)的自驱动,减小了驱动损耗和体二极管导通损耗;③变压器漏感对效率的影响小,可以使用常规的分立式变压器,从而降低成本;④变换器是单相的,结构简单,应用灵活。在理论分析的基础上,搭建了一台四相700kHz 1.2V/130AVRM原理样机验证了理论分析的正确性。

拉米呋定与乙肝疫苗预防HBcAb阳性供肝儿童肝移植术后新发乙肝病毒感染效果的对照研究

目的比较拉米呋定与乙肝疫苗方案预防乙型肝炎核心抗体(hepatitis B core antibody,HBcAb)阳性供肝儿童肝移植术后新发乙型肝炎病毒(hepatitis B virus,HBV)感染效果。方法对天津市第一中心医院自2013年5月—2019年6月251例接受HBcAb阳性供肝儿童肝移植的资料进行回顾性分析,依据采用预防方案的不同分为拉米呋定组和乙肝疫苗组,对两组患儿的新发乙肝病毒感染情况以及临床资料进行比较分析。结果拉米呋定组45例和乙肝疫苗组206例,两组在供受者的临床特征方面无显著差异,两组的新发乙肝病毒感染例数分别为5例(11.1%)和10例(4.9%),发生率无显著统计意义(P=0.075),停用拉米呋定与新发乙肝存在关系。结论单用拉米呋定和乙肝疫苗均是有效预防HBcAb阳性供肝术后新发乙肝的方案,停用拉米呋定会增加新发乙肝的风险。

微小RNA-1303和神经调节蛋白1在甲状腺癌组织中的表达及其临床意义

目的探讨微小RNA-1303(miR-1303)、神经调节蛋白1(NRG1)在甲状腺癌组织中的表达及其临床意义。方法选取2018年5月至2020年8月上海市第一人民医院163例行手术治疗的甲状腺疾病患者的冰冻组织标本,其中甲状腺癌99例、甲状腺腺瘤29例、桥本甲状腺炎20例、结节性甲状腺肿15例,另从本院病理科选取同期25例正常甲状腺组织标本。采用逆转录聚合酶链反应检测miR-1303在组织中的表达。采用免疫组织化学法检测NRG1的表达。分析miR-1303与NRG1表达与甲状腺癌临床病理特征的关系及二者的相关性。结果甲状腺癌、甲状腺腺瘤、桥本甲状腺炎、结节性甲状腺肿及正常甲状腺组织中miR-1303表达量分别为(1.43±0.25)、(1.27±0.21)、(1.19±0.11)、(1.13±0.12)、(1.00±0.08)。甲状腺癌组织中miR-1303表达量高于其他甲状腺组织,差异有统计学意义(F=8.771,P<0.001)。甲状腺癌组织中miR-1303表达量与肿瘤大小、分化程度、包膜浸润、转移淋巴结、病理类型和TNM分期相关(均P<0.001)。甲状腺癌、甲状腺腺瘤、桥本甲状腺炎、结节性甲状腺肿及正常甲状腺组织NRG1阳性表达率分别为51.5%(51/99)、75.9%(22/29)、80.0%(16/20)、80.0%(12/15)、88.0%(22/25)。甲状腺癌组织NRG1阳性表达率低于其他甲状腺组织,差异有统计学意义(χ^(2)=21.629,P=0.001)。甲状腺癌组织中NRG1表达与肿瘤大小、分化程度、包膜浸润、淋巴结转移、TNM分期相关(均P<0.05)。甲状腺癌组织中miR-1303表达量与NRG1表达评分呈显著负相关(r=-0.739,P=0.002)。结论miR-1303、NRG1在甲状腺癌组织中的表达与肿瘤大小、分化程度、包膜浸润、淋巴结转移及TNM分期有关。甲状腺癌组织中miR-1303与NRG1表达呈显著负相关。

Research on Risk Assessment Method of Long-Tube Trailer Road Transportation

Road transport safety has always been paid attention to by the safety production managers of enterprises. In this study, cloud model and analytic hierarchy process were applied to the safety of long-tube trailer transport. The opinions of 30 experts were analyzed, from which 29 key parameters were selected. The study addressed the relevance of the parameters and the possibility of automatic collection and transmission to obtain 12 core risk factors. The macro-safety risk indicator system for long-tube trailers was established based on the identified risk indicators. Finally, a risk assessment model for road transport of long tube trailers consisting of 3 dimensions of likelihood, severity and sensitivity was constructed. This model provides a technical method for strengthening the risk control of road transport of long-tube trailers.

双气囊和单气囊小肠镜对小肠疾病诊断价值的研究

目的比较双气囊和单气囊小肠镜对小肠疾病的诊断价值。方法 2014年7月-2016年8月因疑似小肠疾病而就诊的患者117例,根据治疗方法分为双气囊电子小肠镜组(DBE)68例和单气囊电子小肠镜组(SBE)49例,比较两组患者经口和经肛进镜的检查时间、插镜深度、检出率和治疗率以及不同主诉情况和不同疾病的检出率,评价安全性。结果经口入镜和经肛入镜中,DBE组和SBE组的检查时间、插镜深度、检出率和治疗率比较差异均无统计学意义(P>0.05),两组对不明原因的消化道出血、腹痛、腹泻和其他的小肠疾病的检出率比较差异均无统计学意义(P>0.05),对克罗恩病、恶性肿瘤、良性肿瘤、小肠炎、非特异性溃疡、息肉、憩室和肺结核等的检出率比较差异均无统计学意义(P>0.05)。两组均未见严重并发症。结论 DBE和SBE对小肠疾病的检出率相当。

非平稳性极值风速演化对风机安全性的影响

风力发电机根据历史气象观测数据计算确定的多年一遇风速进行设计和选型,如气候模式在其寿命期内发生明显变化,风速极值分布可能有所改变,将对风机安全性造成突出影响。选用黄山、衡山、成山头、海力素和拐子湖等站点近40 a风速数据,利用考虑和不考虑极值风速趋势性变化的平稳与非平稳极值分布模型(GEV)进行多年一遇极值风速计算。分析长时间尺度下气候变化所致多年一遇极值风速的地域性变化规律及其对风电机组安全性的影响。分析发现海力素、拐子湖和成山头极值风速呈非平稳性,50 a一遇最大风速呈下降趋势,长时间尺度上极值风速的变化对风机安全性有正面影响;黄山极值风速呈非平稳性,长时间尺度上最大可能风速明显高于设计风速,将对风机的安全性提出挑战;衡山极值风速呈平稳性,长时间尺度上极值风速的变化对风机安全性无明显影响。

基于供电网格优化划分的中压配电网规划

新电改背景下,精细化规划成为提高电网企业效益的关键,为此提出了一套基于供电网格优化划分的中压配电网规划思路和方法。首先,确定规划区域主干通道布局,确保土地资源预留。然后,在明确网格划分目的和原则的基础上,基于就近选择负荷备供变电站和负荷聚类方法,实现供电网格在全局范围内的优化划分。最后,分别在各供电网格内,基于其供区分类优选接线模式和一、二次建设改造标准,并进行主干线布线规划。对于过渡年网架,为避免重复改造和便于施工,提出了逐片建设改造的原则。提出的方法在全局统筹基础上遵循"技术可行、经济最优"的基本规划理念,将复杂的配电网络全局规划转化为各优化网格内部的局部规划,使得不同规划人员可以得到基本一致的网格优化划分方案,强化了规划的科学性和确定性,为相关导则修编和细化提供参考,已获得实际应用。

碳酸盐炼制共热耦合甲烷干重整制高附加值化学品发展展望

传统过程工业,诸如我国水泥、钢铁、耐材和电石等行业,都涉及碳酸盐高温热分解过程,其导致的CO_(2)排放量超过了全国工业碳排放总量的50%,大量CO_(2)排放对全球气候产生了不可逆转的影响。因此,如何减少过程工业排放的CO_(2)并且充分利用碳酸盐热分解的余热面临着巨大挑战。为进一步降低该类过程工业的CO_(2)排放量同时降低其热分解的能耗,通过利用地球上储量丰富的温室气体CH_(4),对碳酸盐进行共热耦合重整制备合成气等高附加值产品,有望成为一种环保经济的技术路线。本文总结了(光/热)碳酸盐炼制耦合甲烷干重整反应、醇类重整反应以及CO_(2)捕获反应的最新进展,并且对碳酸盐炼制耦合甲烷干重整反应在理论计算方面的研究进展进行了介绍,进一步结合本课题组近期关于碳酸盐共热耦合甲烷重整的最新结果,我们提出了该类耦合反应的发展展望,为实现CO_(2)的高效转化和减排增效提供了思路。

结肠直肠癌病人D-二聚体升高的研究

目的:通过分析结肠直肠癌(colorectal cancer,CRC)病人凝血状态和相关临床资料,探索CRC与机体高凝的关系。方法:收集我院胃肠外科2018年8月至2019年12月手术治疗CRC病人的临床病理资料。以术前外周血D-二聚体水平为评估机体高凝状态的指标,回顾性分析影响CRC病人机体高凝状态发生的相关因素。结果:249例中104例(41.8%)术前血清D-二聚体高于正常上限(>550μg/L)。其中27例(10.8%)术前D-二聚体显著升高(高于正常上限的3倍,即>1650μg/L)。术后发生静脉血栓栓塞(venous thromboembolism,VTE)7例。多因素分析显示,肿瘤远处转移及脉管内肿瘤侵犯是术前D-二聚体升高的相关因素。肿瘤远处转移病人与无远处转移的术前D-二聚体异常升高占比分别为73.3%、37.6%(P<0.01)。脉管内肿瘤侵犯者和无脉管内肿瘤侵犯者术前D-二聚体异常升高占比分别为51.9%、34.3%(P<0.01)。按术前D-二聚体分组,正常组、升高组、显著升高组出现肿瘤远处转移的比例分别为2.8%、6.5%、22.2%,病理检查证实的脉管内肿瘤侵犯的比例分别为35.2%、48.1%、66.7%。两个比例都随术前D-二聚体水平升高而上升。3组VTE事件发生率分别为0.7%、3.9%、11.1%。VTE发生率与术前D-二聚体水平呈正相关。结论:肿瘤远处转移及脉管内肿瘤侵犯是导致CRC病人机体高凝状态的重要因素,可作为VTE风险的预测指标。