朝阳区北投奥园1314——城市更新与冬奥遗产的融合创新

北投奥园1314项目位于北京市朝阳区,是一个城市更新项目,成功将废弃的厂房转变为体育特色商业园区。该项目通过冬奥遗产的再利用,注入了体育、休闲、文化等多元功能,使园区成为促进社区活力和国际运动时尚体验的新平台。园区的高承租率和丰富的体育赛事活动,展现了其在城市更新中的创新和社会经济效益。

Highly selective photocatalytic reduction of CO_(2) to CH_(4) on electron-rich Fe species cocatalyst under visible light irradiation

Efficient photocatalytic reduction of CO_(2) to high-calorific-value CH4,an ideal target product,is a blueprint for C_(1)industry relevance and carbon neutrality,but it also faces great challenges.Herein,we demonstrate unprecedented hybrid SiC photocatalysts modified by Fe-based cocatalyst,which are prepared via a facile impregnation-reduction method,featuring an optimized local electronic structure.It exhibits a superior photocatalytic carbon-based products yield of 30.0μmol g^(−1) h^(−1) and achieves a record CH_(4) selectivity of up to 94.3%,which highlights the effectiveness of electron-rich Fe cocatalyst for boosting photocatalytic performance and selectivity.Specifically,the synergistic effects of directional migration of photogenerated electrons and strongπ-back bonding on low-valence Fe effectively strengthen the adsorption and activation of reactants and intermediates in the CO_(2)→CH_(4) pathway.This study inspires an effective strategy for enhancing the multielectron reduction capacity of semiconductor photocatalysts with low-cost Fe instead of noble metals as cocatalysts.

Research on Sleeve Grouting Density Detection Based on the Impact Echo Method

Grouting defects are an inherent challenge in construction practices,exerting a considerable impact on the operational structural integrity of connections.This investigation employed the impact-echo technique for the detection of grouting anomalies within connections,enhancing its precision through the integration of wavelet packet energy principles for damage identification purposes.A series of grouting completeness assessments were meticulously conducted,taking into account variables such as the divergent material properties of the sleeves and the configuration of adjacent reinforcement.The findings revealed that:(i)the energy distribution for the highstrength concrete cohort predominantly occupied the frequency bands 42,44,45,and 47,whereas for other groups,it was concentrated within the 37 to 40 frequency band;(ii)the delineation of empty sleeves was effectively discernible by examining the wavelet packet energy ratios across the spectrum of frequencies,albeit distinguishing between sleeves with 50%and full grouting density proved challenging;and(iii)the wavelet packet energy analysis yielded variable detection outcomes contingent on the material attributes of the sleeves,demonstrating heightened sensitivity when applied to ultrahigh-performance concrete matrices and GFRP-reinforced steel bars.

Study on the Application of Vibration Isolation by Using a Trench in Frame Structures

An isolation trench is a simple and effective method to isolate structural vibrations originating from sources of vibration other than earthquakes(machines,traffic,explosions,etc.);however,there is still not a conclusive depth of the isolation trench for frame structures.To investigate the isolation effect of a trench in the frame structure designed for ground vibration,both a field test and finite element analysis were conducted to analyze the reduced effect of the vibration.The vibration reduction analysis was based on the dynamic equation and wave theory.Considering the vibration control of an industrial plant frame,a soil-trench-building finite element model was built to analyze the vibration characteristics of the floor before and after the open isolation trench structure was used.According to the model,a dynamic test was carried out on the frame structure to assess the effect of the vibration reduction by introducing the trench.The results showed that the depth of the trench was the dominating factor in vibration isolation.When the depth of the trench reached 1~1.3 times the wavelength of the Rayleigh wave,the damping effect was the strongest.the width of the trench has little effect on the vibration isolation efficiency,and the trench must be maintained at a certain distance from the building to ensure the vibration damping efficiency.The vibration of each floor was obviously reduced after the trench was built.The vibration damping effect of the trench was significant.

Exploring the mechanism of Ge-Gen-Qin-Lian-Wan against Novel coronavirus pneumonia based on network pharmacology and molecular docking techniques

Objective:To investigate the mechanism of Ge-Gen-Qin-Lian-Wan(GGQLW)for the treatment of Novel coronavirus pneumonia(COVID-19)by network pharmacology and molecular docking methods.Methods:The active compounds and targets of GGQLW were retrieved from the TCMSP database;the targets of COVID-19 were obtained from the OMIM database;the molecular target network of GGQLW for COVID-19 was constructed by Cytoscape software;GO and KEGG analysis were obtained from DAVID database;molecular docking was performed by AutoDock 4.2 and PyMol.Results:A total of 146 active components of GGQLW were obtained;49 therapeutic targets;156 GO enrichment information were involved,including 122 BP,14 CC,and 20 MF;GO results analysis revealed that GGQLW anti-COVID-19 might be mainly through apoptosis,inflammation,immune modulation,and other BP;121 KEGG pathways,and GGQLW anti-COVID-19.The highly relevant signaling pathways were:TNF signaling pathway,Pathways in cancer,HIF-1 signaling pathway;molecular docking results showed that baicalein,berberine,quercetin and formononetin,the core components of GGQLW for COVID-19 treatment,were better bound to SARS-CoV-23CL hydrolases were better bound.Conclusion:The molecular targets and mechanisms of GGQLW for the treatment of COVID-19 were explored through network pharmacology and molecular docking,providing a theoretical basis for the treatment of COVID-19 by GGQLW.

Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma

Renal cell carcinoma,which consists of three main histological subtypes,namely,clear cell renal cell carcinoma(ccRCC),papillary RCC(pRCC),and chromophobe RCC(chRCC),accounts for most kidney cancer cases.ccRCC accounts for approximately 85%of all RcC cases,1 and it is a malignant tumor with multiple molecular features and a poor prognosis.Studies have shown that ccRCC is one of the most immune and vaso-invasive cancer types.2 Considering that ccRCC is not sensitive to either radiotherapy or chemotherapy,targeted therapies.

Characterization of grain growth behaviors by BP-ANN and Sellars models for nickle-base superalloy and their comparisons

In order to deeply understand the grain growth behaviors of Ni80A superalloy,a series of grain growth experiments were conducted at holding temperatures ranging from 1223 to 1423 K and holding time ranging from 0 to 3600 s.A back-propagation artificial neural network(BP-ANN)model and a Sellars model were solved based on the experimental data.The prediction and generalization capabilities of these two models were evaluated and compared on the basis of four statistical indicators.The results show that the solved BP-ANN model has better performance as it has higher correlation coefficient(r),lower average absolute relative error(AARE),lower absolute values of mean value(μ)and standard deviation(ω).Eventually,a response surface of average grain size to holding temperature and holding time is constructed based on the data expanded by the solved BP-ANN model,and the grain growth behaviors are described.

Correspondence between low-energy twin boundary density and thermal-plastic deformation parameters in nickel-based superalloy

To deeply understand and even describe the evolutions of the low-energy twin boundary density(BLDΣ3n)in a thermal-plastic deformation process,an improved twin density model as a function of average grain size and stored energy is developed.For Nimonic 80A superalloy,the model is solved based on the EBSD statistical results of grain size and BLDΣ3n in the specimens compressed at temperatures of 1273−1423 K and strain rates of 0.001−10 s−1.The corresponding relationships of BLDΣ3n with stored energy and grain size varying with temperature and strain rate are clarified by the superimposed contour plot maps.It is summarized that BLDΣ3n increases with increasing stored energy and decreasing grain size,and higher BLDΣ3n with finer grains corresponds with lower temperatures and higher strain rates.Such relationships are described by the improved twin density model,and the prediction tolerance of the solved model is limited in 2.8%.

Protective effects of piperine on the retina of mice with streptozotocin-induced diabetes by suppressing HIF-1/VEGFA pathway and promoting PEDF expression

AIM:To evaluate the protective mechanisms of piperine in the retina of mice with streptozotocin-induced diabetes.METHODS:In experiments in vitro,stimulation by chemical hypoxia was established in ARPE-19 cells.Then,the expression of hypoxia-inducible factor-1α(HIF-1α),vascular endothelial growth factor A(VEGFA),and pigment epithelium-derived factor(PEDF)was assessed at the m RNA and protein levels.In experiments in vivo,diabetes mellitus was established by intraperitoneally injecting 150 mg/kg streptozotocin once.After 3 wk of the onset of diabetes,15 mg/kg piperine was intraperitoneally injected once daily for 1 or 3 wk.Then,the retinal morphology and m RNA and protein expression were assessed.RESULTS:In hypoxia,1-100μmol/L piperine significantly decreased the expression of VEGFA m RNA and increased the expression of PEDF m RNA without affecting HIF-1αm RNA.Meanwhile,100μmol/L piperine substantially decreased the protein level of VEGFA and increased the protein level of PEDF.The HIF-1αprotein level was also hampered by piperine.In the diabetic retina of mice,the morphological damage was alleviated by piperine.Likewise,the retinal vascular leakage was substantially decreased by piperine.Further,the protein levels of HIF-1αand VEGFA were significantly reduced by piperine.Moreover,the level of the antiangiogenic factor of PEDF dramatically increased by piperine.CONCLUSION:Piperine may exert protective effects on the retina of mice with diabetes via regulating the pro-antiangiogenic homeostasis composed of HIF-1/VEGFA and PEDF.

Nanoparticle-Decorated Ultrathin La2O3 Nanosheets as an Effcient Electrocatalysis for Oxygen Evolution Reactions

Electrochemical catalysts for oxygen evolution reaction are a critical component for many renewable energy applications. To improve their catalytic kinetics and mass activity are essential for sustainable industrial applications. Here, we report a rare-earth metal-based oxide electrocatalyst comprised of ultrathin amorphous La2O3 nanosheets hybridized with uniform La2O3 nanoparticles(La2O3@NP-NS). Significantly improved OER performance is observed from the nanosheets with a nanometer-scale thickness. The as-synthesized 2.27-nm La2O3@NP-NS exhibits excellent catalytic kinetics with an overpotential of 310 mV at 10 m A cm^-2, a small Tafel slope of 43.1 mV dec^-1, and electrochemical impedance of 38 Ω. More importantly, due to the ultrasmall thickness, its mass activity, and turnover frequency reach as high as 6666.7 A g^-1 and 5.79 s^-1, respectively, at an overpotential of 310 mV. Such a high mass activity is more than three orders of magnitude higher than benchmark OER electrocatalysts, such as IrO2 and RuO2. This work presents a sustainable approach toward the development of highly e cient electrocatalysts with largely reduced mass loading of precious elements.

Reversible regulation of enzyme-like activity of molybdenum disulfide quantum dots for colorimetric pharmaceutical analysis

Regulating the catalytic activity of nanozymes is significant for their applications in various fields.Here,we demonstrate a new strategy to achieve reversible regulation of the nanozyme’s activity for sensing purpose.This strategy involves the use of zero-dimensional MoS;quantum dots(MQDs)as the building blocks of nanozymes which display very weak peroxidase(POD)-like activity.Interestingly,such POD-like activity of the MQDs largely enhances in the presence of Fe;while diminishes with the addition of captopril thereafter.Further investigations identify the mechanism of Fe;-mediated aggregation-induced enhancement of the POD-like activity and the inhibitory effect of captopril on the enhancement,which is highly dependent on their concentrations.Based on this finding,a colorimetric method for the detection of captopril is developed.This sensing approach exhibits the merits of simplicity,rapidness,reliability,and low cost,which has been successfully applied in quality control of captopril in pharmaceutical products.Moreover,the present sensing platform allows smartphone read-out,which has promising applications in point-of-care testing devices for clinical diagnosis and drug analysis.

Preparation of 2D square-like Bi2S3-BiOCl heterostructures with enhanced visible light-driven photocatalytic performance for dye pollutant degradation

A series of Bi2 S3-BiOCI composites with two-dimensional(2 D) square-like structures were prepared via a two-step anion exchange route.X-ray diffraction(XRD), scanning electron microscopy(SEM), transmission electron microscopy(TEM), and diffuse reflectance spectra(DRS)were used to investigate the properties of the as-prepared Bi_2 S_3-BiOCI heterostructures. The coupling of BiOCl and Bi_2 S_3 induced enhanced photoabsorption efficiency and bandgap narrowing. A reactive brilliant red X-3 B dye was used as a contaminant to test the photocatalytic activity of the obtained Bi_2 S_3-BiOCl samples under visible light irradiation. The sample Bi_2 S_3-BiOCl with a mass ratio of 8:4 exhibited the highest photodegradation efficiency, which was six times higher than that of pure BiOCl. In addition, a mechanism for the enhancement of photocatalytic activity is proposed.

NONLINEAR DYNAMIC INSTABILITY OF DOUBLE-WALLED CARBON NANOTUBES UNDER PERIODIC EXCITATION

A multiple-elastic beam model based on Euler-Bernoulli-beam theory is presented to investigate the nonlinear dynamic instability of double-walled nanotubes. Taking the geometric nonlinearity of structure deformation, the effects of van der Waals forces as well as the non- coaxial curvature of each nested tube into account, the nonlinear parametric vibration governing equations are derived. Numerical results indicate that the double-walled nanotube （DWNT） can be considered as a single column when the van der Waals forces are sufficiently strong. The stiffness of medium could substantially reduce the area of the nonlinear dynamic instability region, in particular, the geometric nonlinearity can be out of account when the stiffness is large enough. The area of the principal nonlinear instability region and its shifting distance aroused by the nonlinearity both decrease with the increment of the aspect ratio of the nanotubes.

A Review of Air Pollution and Control in Hebei Province, China

Hebei is one of the most air polluted provinces in China. According to the Ministry of Environmental Protection (MEP) for the severe fog-haze month of Jan. 2013, seven of the top ten most polluted cities in China are located in Hebei Province. In this study, the air pollution history and status of the Hebei Province are reviewed and discussed, using the governmental published Air Pollution Index (API), the academic observations by various scientific research groups and the long-term statistics of visibility and haze frequencies. It is found that within the Hebei Province, the air pollution in the southern cities is much more severe than the northern cities. Particulate matter (PM) is undoubtedly the major air pollutant, sulfur dioxide (SO2) and nitrogen oxides (NOX) pollutions are also unnegligible. Ozone (O3) pollution in larger cities, such as Shijiazhuang, is significant. Air pollution control history from 1998 is discussed as well. Although Hebei Province has made a great effort on air quality, the pollutant emissions, such as SO2 and fly ash, showed a notable increase in 2001 to 2006. However, after 2006 the emissions started to decrease due to the strict implementation of the national 11th Five Year Plan (FYP). In addition, regional jointly air pollution control and prevention strategies are expected in the future to substantially change the severe air pollution status in Hebei Province.

Research into the inversion of the induced polarization relaxation time spectrum based on the uniform amplitude sampling method

The induced polarization relaxation time spectrum（RTS） reflects the distribution of rock pore size,which is a key factor in estimating the oil or water storage capacity of strata.However,as the data acquisition and transmission abilities of well logging instruments are much limited due to the underground environment,it is necessary to explore suitable sampling methods which can be used to obtain an accurate RST with less sampling data.This paper presents a uniform amplitude sampling method（UASM）,and compares it with the conventional uniform time sampling method（UTSM） and logarithm time sampling method（LTSM） in terms of the adaptability to different strata,RTS inversion accuracy,and stratum vertical resolution.Numerical simulation results show that the UASM can obtain high inversion accuracy of RTS with different kinds of pore size distribution formation,with high dynamic ranges of pore size,and with a small number of sampling points.The UASM,being able to adapt to the attenuation speed of polarization curve automatically,thus has the highest vertical resolution.The inversion results of rock samples also show that the UASM is superior to the UTSM and LTSM.

Late hCG administration yields more good quality embryos and favors the overall IVF outcome

Context: Optimal timing of hCG administration is a crucial step for successful IVF. Currently used standard hCG administration timing is not always practically possible due to weekends break or other reasons. Sometimes hCG needs to be administrated earlier or later than standard timing. Aim: To find out whether earlier or later hCG administration gives better IVF outcome. Setting and Design: A retrospective study on patients who underwent conventional IVF treatment. Methods and Material: Based on hCG timing, the patients were divided into three groups: the early hCG group where the hCG was given when less than three follicles ≥ 17 mm;the standard hCG group where the hCG was given when three or more follicles ≥ 17 mm;and the late hCG group where the hCG was given 1 to 3 days after the standard timing. The number of retrieved mature oocytes, the fertilization rate, the number of good quality embryos, the pregnancy rate and the live birth rate were compared among three groups. Statistical Analysis: x2 test, fisher exact test and Student t-test were used. Results: in total, 289 patients, 305 IVF cycles and 2784 oocytes were analyzed. The late hCG group has significantly larger number of MII oocytes, fertilized oocytes and good quality embryos per IVF cycle, when compared with the early hCG group. The fertilization rate, the pregnancy rate and the live birth rate per IVF cycle were similar among the three groups. Conclusion: Although the delayed administration of hCG did not favor IVF outcome per IVF cycle, the cumulative pregnancy rate is likely to be improved with consideration of higher yield of good quality embryos.

Evidence of potential change in nonsequential double ionization

Recently,the quantitative rescattering model(QRS)for nonsequential double ionization(NSDI)is modified by taking into account the potential change(PC)due to the presence of electric field at the time of recollision.Using the improved QRS model,we simulate the longitudinal momentum distributions of doubly charged ions He2+by projecting the correlated two-electron momentum distributions for NSDI of He onto the main diagonal.The obtained results are compared directly with the experimental data at different intensities.It is found that when the PC is considered,the width of momentum distributions reduces and the agreement between theory and experiment is improved.

COMMUTATORS OF MULTIPLIERS ON HARDY SPACES

Let T be the multiplier operator associated to a multiplier m, and [b, T] be the commutator generated by T and a BMO function b. In this paper, the authors have proved that [b,T] is bounded from the Hardy space H^1（R^n） into the weak L^1 （R^n） space and from certain atomic Hardy space Hb^1 （R^n） into the Lebesgue space L^1 （R^n）, when the multiplier m satisfies the conditions of Hoermander type.

Experimental Investigation on Fracture Performance of Short Basalt Fiber Bundle Reinforced Concrete

In this paper,a notched three-point bending test is used to study the fracture performance of the short basalt fiber bundle reinforced concrete(SBFBRC).To compare and analyze the enhancement effect of different diameters and different content of basalt fiber bundles on the fracture performance of concrete,some groups are set up,and the P-CMOD curves of each group of specimens are measured,and the fracture toughness and fracture energy of each control group are calculated.The fracture toughness and fracture energy are two important fracture performance parameters to study the effect and law of the new basalt fiber bundles on the fracture performance of concrete.The research results show that the diameter and content of the new basalt fiber bundles have a certain effect on the fracture performance of concrete.With the increase of the content of basalt fiber bundles,the peak load,crack initiation toughness,instability toughness and fracture energy of SBFBRC are greatly improved compared with the benchmark group.When the fiber bundle diameter is 0.2 mm,the peak load increases by 69.5%compared with the reference group.The instability toughness reaches its maximum value at 0.2 mm diameter,which is 59.7%higher than the benchmark.

Distribution Characteristics of δ^(13) C during the Decomposition Process of Soil Organic Matters under Different Climates and in Different Vegetation Zones

[ Obiective] The research aims to study distribution characteristics of 613C during the decomposition process of soil organic matters under different climates and in different vegetation zones.[Method] This essay measures the values of δ^13Corg in vadous soil profiles from different climatic zones and vegetation zones in order to obtain the precise corrected value. The 14 profiles of the following soil types in different zones are collected： brown earths in arid and semi-arid regions covered by C3 forests, yellow earths in humid zone covered by shrubs and forest, sandy loess from arid area covered by sparse vegetation, Ioess-paleosols in arid and semi-arid regions covered by C3/C4 grassland, yellow soils and paleosols in semi humid regions covered by C3/C4 grassland and yellow earths in humid areas covered by C3/C4 grassland. The measurement of δ^3Corg and standardized testing of the organic carbon are carried with above-mentioned profiles. An unified and skewed trend is not observed in the variation of δ^3C values in these profiles. A discussion about the causes of distribution features is held in this essay. [Result] If the measurement of δ^3C in the organic matters of paleosols is adopted in order to precisely rebuild the historical vegetation cover, the kinetic fractionation should be taken into consideration to calculate the 6TM Corg in the prolife from the soils that is exclusively covered by C3 plants; the δ^3 Corg in the organic matters of the sand loess in the arid regions is affected by the contribution from basis; during the long-term decomposition of the organic matters in soils covered by C3/ C4 grassland, the range of δ^3Corg is under 2%. [ Conclusion] In view of the mixed vegetation cover, the profile distribution of δ^3Corg in different geographic periods is more likely to indicate the ratio of C4 plants to C3 plants.