To improve the comprehensive mechanical properties of Al-Si-Cu alloy,it was treated by a high-pressure torsion process,and the effect of the deformation degree on the microstructure and properties of the Al-Si-Cu allo...To improve the comprehensive mechanical properties of Al-Si-Cu alloy,it was treated by a high-pressure torsion process,and the effect of the deformation degree on the microstructure and properties of the Al-Si-Cu alloy was studied.The results show that the reinforcements(β-Si andθ-CuAl_(2)phases)of the Al-Si-Cu alloy are dispersed in theα-Al matrix phase with finer phase size after the treatment.The processed samples exhibit grain sizes in the submicron or even nanometer range,which effectively improves the mechanical properties of the material.The hardness and strength of the deformed alloy are both significantly raised to 268 HV and 390.04 MPa by 10 turns HPT process,and the fracture morphology shows that the material gradually transits from brittle to plastic before and after deformation.The elements interdiffusion at the interface between the phases has also been effectively enhanced.In addition,it is found that the severe plastic deformation at room temperature induces a ternary eutectic reaction,resulting in the formation of ternary Al+Si+CuAl_(2)eutectic.展开更多
目的分析关于肺癌精准治疗的研究热点与研究前沿,预测该领域未来研究方向。方法通过CiteSpace软件检索Web of Science Core Collection(WoSCC)数据库中2018年1月1日至2022年12月31日期间该领域的文章进行可视化分析,分析内容包括年度分...目的分析关于肺癌精准治疗的研究热点与研究前沿,预测该领域未来研究方向。方法通过CiteSpace软件检索Web of Science Core Collection(WoSCC)数据库中2018年1月1日至2022年12月31日期间该领域的文章进行可视化分析,分析内容包括年度分布、国家、机构、作者、高频关键词等。结果共检索到1583篇相关文献,发文量总体呈上升趋势。81个国家/地区、290个机构、263位作者参与了肺癌精准治疗领域的相关研究。关键词分析显示现阶段“靶向治疗”“液体活检”“表皮生长因子受体(EGFR)”“酪氨酸激酶抑制剂(TKI)”“循环肿瘤细胞(CTCs)”“循环肿瘤DNA(ctDNA)”和“二代测序技术(NGS)”等词为该领域的热点关键词。结论目前肺癌精准治疗相关研究正处于快速发展阶段。未来需对当前研究热点进行更加深入的研究,加强跨国家及跨机构的高质量合作,为肺癌精准治疗提供更为前沿的方向。展开更多
基金Funded by the National Natural Science Foundation of China(No.51905215)Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.SJCX23_1233)+1 种基金Major Scientific and Technological Innovation Project of Shandong Province of China(No.2019JZZY020111)the National College Students Innovation and Entrepreneurship Training Program of China(No.CX2022415)。
文摘To improve the comprehensive mechanical properties of Al-Si-Cu alloy,it was treated by a high-pressure torsion process,and the effect of the deformation degree on the microstructure and properties of the Al-Si-Cu alloy was studied.The results show that the reinforcements(β-Si andθ-CuAl_(2)phases)of the Al-Si-Cu alloy are dispersed in theα-Al matrix phase with finer phase size after the treatment.The processed samples exhibit grain sizes in the submicron or even nanometer range,which effectively improves the mechanical properties of the material.The hardness and strength of the deformed alloy are both significantly raised to 268 HV and 390.04 MPa by 10 turns HPT process,and the fracture morphology shows that the material gradually transits from brittle to plastic before and after deformation.The elements interdiffusion at the interface between the phases has also been effectively enhanced.In addition,it is found that the severe plastic deformation at room temperature induces a ternary eutectic reaction,resulting in the formation of ternary Al+Si+CuAl_(2)eutectic.
文摘目的分析关于肺癌精准治疗的研究热点与研究前沿,预测该领域未来研究方向。方法通过CiteSpace软件检索Web of Science Core Collection(WoSCC)数据库中2018年1月1日至2022年12月31日期间该领域的文章进行可视化分析,分析内容包括年度分布、国家、机构、作者、高频关键词等。结果共检索到1583篇相关文献,发文量总体呈上升趋势。81个国家/地区、290个机构、263位作者参与了肺癌精准治疗领域的相关研究。关键词分析显示现阶段“靶向治疗”“液体活检”“表皮生长因子受体(EGFR)”“酪氨酸激酶抑制剂(TKI)”“循环肿瘤细胞(CTCs)”“循环肿瘤DNA(ctDNA)”和“二代测序技术(NGS)”等词为该领域的热点关键词。结论目前肺癌精准治疗相关研究正处于快速发展阶段。未来需对当前研究热点进行更加深入的研究,加强跨国家及跨机构的高质量合作,为肺癌精准治疗提供更为前沿的方向。
