The application of superconducting(SC)technology enables magnets to excite strong fields with small footprints,which has great potential for miniaturizing proton therapy gantries.However,the slow ramping rate of SC ma...The application of superconducting(SC)technology enables magnets to excite strong fields with small footprints,which has great potential for miniaturizing proton therapy gantries.However,the slow ramping rate of SC magnets results in a low treatment efficiency compared with normal-conducting(NC)gantries.To address this problem,this study proposes a compact proton therapy gantry design with a large momentum acceptance utilizing alternating-gradient canted-cosine-theta(AG-CCT)SC magnets.In our design,a high-transmission degrader is mounted in the middle of the gantry,and the upstream beamline employs NC magnets with small apertures.Downstream of the degrader,large-bore AG-CCT magnets with strong alternating focusing gradients are set symmetrically as a local achromat,which realizes a momentum acceptance of 20%(or 40%in the energy domain).Therefore,only three magnetic working points are required to cover a treatment energy of 70-230 Me V.Owing to the large momentum acceptance,the proton beam after the degrader can be directly delivered to the isocenter without truncating its energy spectrum,which can significantly increase the treatment efficiency but causes severe dispersion effects during pencil beam scanning.Therefore,a compensation method was introduced by tuning the normal and skewed quadrupoles during the scanning process.As a result,the new gantry not only presents a remarkable reduction in the size and weight of the facility but also shows good potential for fast treatment.展开更多
To guarantee the exact proton dose applied to patients and ensure treatment safety while disrupting and destroying tumor cells,it is essential to accurately monitor the proton beam current in real time during patient ...To guarantee the exact proton dose applied to patients and ensure treatment safety while disrupting and destroying tumor cells,it is essential to accurately monitor the proton beam current in real time during patient treatment.Because clinical treatment requires a proton beam current in the∼nA range,nondestructive beam current monitors(BCMs)are preferred to minimize the degradation of beam quality.However,this poses significant challenges in accurately monitoring such extremely low beam intensities.This study proposes a cavity-type BCM equipped with a dielectric plate to reduce its dimensions and achieve sufficient measurement sensitivity for practical requirements.A prototype cavity BCM was fabricated,and off-line testing was performed using a metal wire to simulate the beam to study its performance.Both the simulation and experi-mental results showed that the cavity BCM could measure ultralow proton beam currents with a resolution up to 0.03 nA.展开更多
A proton therapy(PT)facility with multiple treatment rooms based on the superconducting cyclotron scheme is under development at Huazhong University of Science and Technology(HUST).This paper attempts to describe the ...A proton therapy(PT)facility with multiple treatment rooms based on the superconducting cyclotron scheme is under development at Huazhong University of Science and Technology(HUST).This paper attempts to describe the design considerations and implementation of the PT beamline from a systematic viewpoint.Design considerations covering beam optics and the influence of high-order aberrations,beam energy/intensity modulation,and beam orbit correction are described.In addition to the technical implementation of the main beamline components and subsystems,including the energy degrader,fast kicker,beamline magnets,beam diagnostic system,and beamline control system are introduced.展开更多
基金supported by the National Natural Science Foundation of China(No.11975107,12205111)。
文摘The application of superconducting(SC)technology enables magnets to excite strong fields with small footprints,which has great potential for miniaturizing proton therapy gantries.However,the slow ramping rate of SC magnets results in a low treatment efficiency compared with normal-conducting(NC)gantries.To address this problem,this study proposes a compact proton therapy gantry design with a large momentum acceptance utilizing alternating-gradient canted-cosine-theta(AG-CCT)SC magnets.In our design,a high-transmission degrader is mounted in the middle of the gantry,and the upstream beamline employs NC magnets with small apertures.Downstream of the degrader,large-bore AG-CCT magnets with strong alternating focusing gradients are set symmetrically as a local achromat,which realizes a momentum acceptance of 20%(or 40%in the energy domain).Therefore,only three magnetic working points are required to cover a treatment energy of 70-230 Me V.Owing to the large momentum acceptance,the proton beam after the degrader can be directly delivered to the isocenter without truncating its energy spectrum,which can significantly increase the treatment efficiency but causes severe dispersion effects during pencil beam scanning.Therefore,a compensation method was introduced by tuning the normal and skewed quadrupoles during the scanning process.As a result,the new gantry not only presents a remarkable reduction in the size and weight of the facility but also shows good potential for fast treatment.
基金supported by the National Natural Science Foundation of China(No.12235005)the National Key Research and Development Program of China(No.2016YFC0105309).
文摘To guarantee the exact proton dose applied to patients and ensure treatment safety while disrupting and destroying tumor cells,it is essential to accurately monitor the proton beam current in real time during patient treatment.Because clinical treatment requires a proton beam current in the∼nA range,nondestructive beam current monitors(BCMs)are preferred to minimize the degradation of beam quality.However,this poses significant challenges in accurately monitoring such extremely low beam intensities.This study proposes a cavity-type BCM equipped with a dielectric plate to reduce its dimensions and achieve sufficient measurement sensitivity for practical requirements.A prototype cavity BCM was fabricated,and off-line testing was performed using a metal wire to simulate the beam to study its performance.Both the simulation and experi-mental results showed that the cavity BCM could measure ultralow proton beam currents with a resolution up to 0.03 nA.
基金the National Key Research and Development Program of China(No.2016YFC0105305)the National Natural Science Foundation of China(11975107)the Program for HUST Academic Frontier Youth Team.
文摘A proton therapy(PT)facility with multiple treatment rooms based on the superconducting cyclotron scheme is under development at Huazhong University of Science and Technology(HUST).This paper attempts to describe the design considerations and implementation of the PT beamline from a systematic viewpoint.Design considerations covering beam optics and the influence of high-order aberrations,beam energy/intensity modulation,and beam orbit correction are described.In addition to the technical implementation of the main beamline components and subsystems,including the energy degrader,fast kicker,beamline magnets,beam diagnostic system,and beamline control system are introduced.