PbGIF1 promoting cell-proliferation in pear fruit is transcriptionally activated by Pb RR1

As a cell proliferation regulator involved in wide biological processes in plants,GRF-INTERACTING FACTOR(GIF)controls different tissues development.However,whether GIF participates in fruit development remains unclear.According to transcriptome data,we identified PbGIF1was highly expressed during fruit development in cytokinins induced parthenocarpy pear.In the present study,the biofunction of PbGIF1 was initially verified.Overexpression of PbGIF1 promoted fruit size of transgenic tomato.The size of flesh fruit was not affected by cell expansion but the cell proliferation was promoted by overexpressing Pb GIF1.The accelerated cell proliferation process was also observed in PbGIF1-overexpressed transgenic pear fruit calli.The transcriptional regulation of cytokinins on PbGIF1 was further confirmed by exogenous CPPU treatments in pear fruitlets.To investigate the underlying mechanism,the cytokinins-responded factor,PbRR1,was further focused on.The results of Yeast-one-hybrid assay suggested that PbRR1 can bind to the promoter sequence of PbGIF1.The transcriptional activation of PbRR1 on PbGIF1 was also confirmed by Dual-Luciferase assays.Taken together,the results showed that cytokinins control pear fruit development via the transcriptional activation of PbGIF1 by PbRR1.

新型杂合四芳烯光控分子开关的设计合成与性能测试

围绕分子开关及聚集诱导发光的科研热点领域进行本科教学实验设计,将光致变色二芳烯巧妙嵌合于具有聚集诱导发光性能的四芳烯体系中,制备得到兼具变色和发光功能的新型杂合四芳烯光控荧光分子开关,科教融合,将科研前沿引入到本科实验教学。从物质的制备、分离提纯、结构表征和性能测试等方面进行了综合实验探索。本实验分子设计简练新颖,内容丰富,现象明显,在综合运用和巩固本科学习的基本理论和基本操作的基础上,激发学生的科研兴趣,培养团结协作和突破创新的科学精神。

Novel Batch Polishing Method of Ceramic Cutting Inserts for Reducing Tool Wear

Ceramic cutting inserts are a type of cutting tool commonly used in high-speed metal cutting applications.However,the wear of these inserts caused by friction between the workpiece and cutting inserts limits their overall effectiveness.In order to improve the tool life and reduce wear,this study introduces an emerging method called magnetic field-assisted batch polishing(MABP)for simultaneously polishing multiple ceramic cutting inserts.Several polishing experiments were conducted under different conditions,and the wear characteristics were clarified by cutting S136H steel.The results showed that after 15 min of polishing,the surface roughness at the flank face,edge,and nose of the inserts was reduced to below 2.5 nm,6.25 nm,and 45.8 nm,respectively.Furthermore,the nose radii of the inserts did not change significantly,and there were no significant changes in the weight percentage of elements before and after polishing.Additionally,the tool life of the batch polished inserts was found to be up to 1.75 times longer than that of unpolished inserts.These findings suggest that the MABP method is an effective way to mass polish ceramic cutting inserts,resulting in significantly reduced tool wear.Furthermore,this novel method offers new possibilities for polishing other tools.

Research and application of composite stochastic resonance in enhancement detection

Aiming at the problem that the intermediate potential part of the traditional bistable stochastic resonance model cannot be adjusted independently, a new composite stochastic resonance(NCSR) model is proposed by combining the Woods–Saxon(WS) model and the improved piecewise bistable model. The model retains the characteristics of the independent parameters of WS model and the improved piecewise model has no output saturation, all the parameters in the new model have no coupling characteristics. Under α stable noise environment, the new model is used to detect periodic signal and aperiodic signal, the detection results indicate that the new model has higher noise utilization and better detection effect.Finally, the new model is applied to image denoising, the results showed that under the same conditions, the output peak signal-to-noise ratio(PSNR) and the correlation number of NCSR method is higher than that of other commonly used linear denoising methods and improved piecewise SR methods, the effectiveness of the new model is verified.

The In-Flight Realtime Trigger and Localization Software of GECAM

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2020 December 10.We developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic Box.This onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation system.This paper provides a detailed description of the design and development of the trigger and localization software system for GECAM.It covers the general design,workflow,the main functions,and the algorithms used in the system.The paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

Seven-years post allogeneic hematopoietic stem cell transplantation pure red cell aplastic anemia cured with daratumumab:A case report and review of literature

BACKGROUND Allogeneic hematopoietic stem cell transplantation(Allo-HSCT)is currently the only viable method of curing patients with acute myeloid leukaemia.In 30%to 50%of patients,donors and recipients have some level of ABO blood group incompatibility.ABO blood group incompatibility can cause antibodies against the donor's red blood cells to persist in the recipient's body,resulting in a delay of several months in the recovery of red blood cells.A number of different treatments have been reported for post-transplant pure red cell aplastic anaemia(PRCA),such as plasmapheresis,donor lymphocyte infusions,anti-thymocyte globulin,rituximab and steroids.CASE SUMMARY A 41-year-old female diagnosed with acute myeloid leukaemia underwent peripheral blood allogeneic haematopoietic stem cell transplantation in November 2013 from an HLA matched unrelated donor.The donor was AB-positive and the recipient was O-positive.The patient was diagnosed with PRCA three months after receiving the donor stem cell transplant.After failing multiple lines of therapy,the patient applied for daratumumab.After receiving three doses of daratumumab,the patient developed a reticulocyte response and no longer required CONCLUSION The use of daratumumab anti-CD38 for the remove of plasma cells is safe and effective and may be tried for refractory patients with PRCA after undergoing allo-HSCT for ABO incompatibility.

Understanding the educational inequalities in suicide attempts and their mediators:a Mendelian randomisation study

Background Educational inequalities in suicide have become increasingly prominent over the past decade.Elucidating modifiable risk factors that serve as intermediaries in the impact of low educational attainment on suicide has the potential to reduce health disparities.Aims To examine the risk factors that mediate the relationship between educational attainment and suicide attempts and quantify their contributions to the mediation effect.Methods We conducted a two-sample Mendelian randomisation(MR)analysis to estimate the causal effect of educational attainment on suicide attempts,utilising genome-wide association study summary statistics from the Integrative Psychiatric Research(iPSYCH;6024 cases and 44240 controls)and FinnGen(8978 cases and 368299 controls).We systematically evaluated 42 putative mediators within the causal pathway connecting reduced educational attainment to suicide attempts and employed two-step and multivariable MR to quantify the proportion of the mediated effect.Results In the combined analysis of iPSYCH and FinnGen,each standard deviation(SD)decrease in genetically predicted educational attainment(equating to 3.4 years of education)was associated with a 105%higher risk of suicide attempts(odds ratio(OR):2.05;95%confidence interval(Cl):1.81 to 2.31).0f the 42 risk factors analysed,the two-step MR identified five factors that mediated the association between educational attainment and suicide attempts.The respective proportions of mediation were 47%(95%Cl:29%to 66%)for smoking behaviour,36%(95%Cl:0%to 84%)for chronic pain,49%(95%Cl:36%to 61%)for depression,35%(95%Cl:12%to 59%)for anxiety and 26%(95%Cl:18%to 34%)for insomnia.Multivariable MR implicated these five mediators collectively,accounting for 68%(95%Cl:40%to 96%)of the total effect.Conclusions This study identified smoking,chronic pain and mental disorders as primary intervention targets for attenuating suicide risk attributable to lower educational levels in the European population.

紫外/氯工艺中磺胺类药物的转化:机理和毒性评价

磺胺类药物(sulfonamides,SAs)是一种常用的抗菌药物,由于在水生环境中经常被发现,因此备受关注。本文研究了紫外/氯(UV/Cl)工艺中3种磺胺类药物的转化过程及其产物毒性变化,并与氯化、紫外/过氧化氢(UV/H_(2)O_(2))工艺进行比较。结果显示,磺胺类药物在UV/Cl工艺中转化效率最高,氯类自由基在其中起到关键作用。在不同pH条件下,磺胺类药物在UV/Cl工艺中的转化效率会随pH值的增加而降低,但在pH值接近pKa值时突然升高,推测该现象与反应活性成分和SAs形态的变化有关。此外,对转化产物毒性的进一步研究发现,UV/Cl工艺的转化产物毒性最低(发光菌抑制率为6.99%—12.06%),但是未能显著降低SAs原溶液的毒性,并且由于氯代产物的出现,磺胺噻唑在转化后表现出更高的毒性。

Construction and Practice of a Practical Teaching System for Normal Universities Based on Ability Cultivation

This study aims to explore the effect of project-based teaching methods on improving students’ abilities in normal universities. This study delves into the practice teaching system based on ability training implemented in normal universities, examining the application of this teaching model in teacher education and the potential challenges it may encounter. Our case study reveals that the Project-Based Learning (PBL) approach can effectively transform students from passive recipients of knowledge into active problem solvers, thereby enhancing their critical thinking, problem-solving, teamwork, and communication skills. However, challenges do exist, including ensuring active participation from all students, providing equal opportunities for each student to develop and showcase their abilities, and completing complex projects within a limited timeframe. Therefore, teachers may need to adjust their teaching strategies, and schools need to provide more resources and support. These adjustments can help the practice teaching system based on ability training better serve teacher education and offer students a higher-quality educational experience.

金属卟啉修饰的多孔聚苯胺基氧还原电催化剂

碳基非金属氧还原(ORR)电催化剂的研究近年来发展迅速,通过掺入杂原子等方法虽获得了一定的ORR活性,但仍需进一步提高。以此类电催化剂为基体,引入更多的活性位点,有可能获得更好的ORR活性。本文首先以带负电荷的SiO_(2)纳米球通过静电作用吸附带正电荷的质子化苯胺分子,再通过聚合反应实现聚苯胺(PANI)对SiO_(2)纳米球的包覆,之后将四甲氧基苯基铁卟啉(FeP)沉积在PANI表面,经高温热解,并去除SiO_(2)模板,得到了一种新型的多孔ORR电催化剂。在0.1 mol·L^(−1) KOH水溶液中,电催化剂的ORR半波电位达0.843 V(vs.可逆氢电极(RHE)),优于文献报道的大部分碳基非金属ORR电催化剂,与商业Pt/C相近。显著提高的ORR活性可能源于孔结构(平均孔径18 nm,孔容1.1 cm^(3)·g^(−1))、高比表面积(687.5 m^(2)·g^(−1))和高氮含量(6.4%)。在加速耐久性测试中,电催化剂的ORR半波电位衰减25 mV,与其它碳基非金属ORR电催化剂相当,且远优于商业Pt/C(衰减74 mV)。另外,电催化剂应用于氢氧根交换膜燃料电池(HEMFC)时的单池峰值功率密度达42 mW·cm−2。

Stress distribution and surrounding rock control of mining near to the overlying coal pillar in the working face

The occurrence of overlying coal pillar(OCP)exerts a strong effect on the stress and strain distribution of the surrounding rock in the stope.In this paper,the stress distribution characteristics are analyzed via the numerical calculation with the account of OCP presence or absence.In addition,this study revealed the joint effect of side pressure relief area of the goaf and stress concentration in OCP on the final stress distribution.Furthermore,the rules of abutment stress distribution affected by three influencing factors,namely horizontal-vertical distances between OCP and working face and buried depth of OCP,are analyzed.The functional model linking the peak stress of surrounding rock with the above influencing factors is developed.The field application of the above results proved that the rib spalling and deformation of a 2.95 m-high and 5.66 m-wide roadway could be efficiently controlled by rationally adjusting working states of the support,and adopting the hydraulic prop coordinated with the p type metal beam and anchor cable to strengthen the surrounding rock of working face and roadway,respectively.The proposed measures are considered appropriate to satisfy the safe operation requirements.

High-resolution crustal structure of the Yinchuan basin revealed by deep seismic reflection profiling:implications for deep processes of basin

The Yinchuan basin, located on the western margin of the Ordos block, has the characteristics of an active continental rift. A NW-striking deep seismic reflection profile across the center of Yinchuan basin precisely revealed the fine structure of the crust. The images showed that the crust in the Yinchuan basin was characterized by vertical stratifications along a detachment located at a two-way travel time（TWT） of 8.0 s.The most outstanding feature of this seismic profile was the almost flat Mohorovicˇic′ discontinuity（Moho） and a high-reflection zone in the lower crust. This sub-horizontal Moho conflicts with the general assumption of an uplifted Moho under sedimentary basins and continental rifts, and may indicate the action of different processes at depth during the evolution of sedimentary basins or rifts.We present a possible interpretation of these deep processes and the sub-horizontal Moho. The high-reflection zone, which consists of sheets of high-density, mantlederived materials, may have compensated for crustal thinning in the Yinchuan basin, leading to the formation of a sub-horizontal Moho. These high-density materials may have been emplaced by underplating with mantlesourced magma.

Core Outcome Set for Clinical Trials on Coronavirus Disease 2019(COS-COVID)

自2019年12月新型冠状病毒肺炎(Coronavirus Disease 2019, COVID-19)暴发以来,已有大量相关临床研究完成注册或已启动。然而,不同研究间临床结局指标存在显著的异质性,同时一些不关键的指标会造成研究资源的浪费。本研究旨在构建COVID-19临床试验核心结局指标集(core outcome set, COS),为相关临床研究方案设计、开展和证据转化提供参考。本研究的实施参照《有效性试验核心结局指标(COMET)手册》(1.0版),研究组成员包括呼吸系统和危重医学、中医学、循证医学、临床药理学、统计学专家以及医学杂志编辑等。通过检索临床试验注册网站(chictr.org.cn和clinicaltrials.gov)中COVID-19相关临床研究方案,提取方案中的结局指标,形成指标池。78个COVID-19临床试验方案纳入研究,收集结局指标259个,合并规范后确定132个结局指标,涉及7个指标域。经遴选,形成了包括58个结局指标在内的初始指标清单。经过两轮德尔菲调查和一轮共识会议,最终确立针对COVID-19不同临床分型的核心指标集(COS-COVID)。COS-COVID包括1个轻型指标(病毒核酸检测转阴时间)、4个普通型指标(住院时间、复合事件发生率、临床症状积分和病毒核酸检测转阴时间)、5个重型指标(复合事件发生率、住院时间、PaO2/FiO2、机械通气时间和病毒核酸检测转阴时间)、1个危重型指标(全因死亡率)及1个康复期指标(肺功能)。COS-COVID作为目前临床评价COVID-19干预效果最具临床价值及操作性的指标集合,对证据评估和决策具有重要意义。随着对疾病认知的不断深入和COS-COVID应用的反馈,课题组将对本核心指标集进行进一步完善并更新。

A novel design of 3D carbon host for stable lithium metal anode

Rational design of porous conductive hosts with high electrical conductivity,large surface area,and adequate interior space is desirable to suppressing dendritic lithium growth and accommodating large volume change of lithium metal anode during the Li plating/stripping process.However,due to the conductive nature of the conductive hosts,Li is easily deposited directly on the top of the hosts,which hinders it from fully functioning.To circumvent the issue,in this study,we designed a novel porous carbon host with a gradient-pore-size structure based on one-dimensional(1D)carbon with different diameters.With this kind of host,stable cycling with high and stable Coulombic efficiency of~98%is achieved at 0.5 mA cm^(−2) with an areal capacity of 1 mAh cm^(−2) over 320 cycles.In contrast,the normal three-dimensional(3D)carbon nanotube host presents a moss-like Li morphology with wildly fluctuating Coulombic efficiency after 100 cycles.The results reveal that the unique gradient-pore-size structure of the 3D conductive host greatly improves the performance of lithium metal batteries.

Frozen subduction in the Yangtze block:insights from the deep seismic profiling and gravity anomaly in east Sichuan fold belt

The Sichuan basin is the main part of the middle-upper Yangtze block, which has been experienced a long-term tectonic evolution since Archean. The Yangtze block was regarded as a stable block until the collision with the Cathaysia block in late Neoproterozoic. A new deep seismic reflection profile conducted in the eastern Sichuan fold belt（ESFB） discovered a serials of south-dipping reflectors shown from lower crust to the mantle imply a frozen subduction zone within the Yangtze block. In order to prove the speculation, we also obtain the middle-lower crustal gravity anomalies by removing the gravity anomalies induced by the sedimentary rocks and the mantle beneath the Moho, which shows the mid-lower crustal structure of the Sichuan basin can be divided into eastern and western parts. Combined with the geochronology and Aeromagnetic anomalies, we speculated the Yangtze block was amalgamated by the West Sichuan and East Sichuan blocks separated by the Huayin-Chongqing line. The frozen subduction zone subsequently shifted to a shear zone accommodated the lower crustal shortening when the decollement at the base of the Nanhua system functioned in the upper plate.

The thickness and structural characteristics of the crust across Tibetan plateau from active-sources seismic profiles

The Tibetan plateau as one of the youngest orogen on the Earth was considered as the result of continent-continent collision between the Eurasian and Indian plates. The thickness and structure of the crust beneath Tibetan plateau is essential to understand deformation behavior of the plateau. Active-source seismic profiling is most available geophysical method for imaging the structure of the continental crust. The results from more than 25 active-sources seismic profiles carried out in the past twenty years were reviewed in this article. A preliminary cross crustal pattern of the Tibetan Plateau was presented and discussed. The Moho discontinuity buries at the range of 60-80 km on average and have steep ramps located roughly beneath the sutures that are compatible with the successive stacking/accretion of the former Cenozoic blocks northeastward. The deepest Moho （near 80 km） appears closely near IYS and the crustal scale thrust system beneath southern margin of Tibetan plateau suggests strong dependence on collision and non-distributed deformation there. However, the -20 km order of Moho offsets hardly reappears in the inline section across northern Tibetan plateau. Without a universally accepted, convincing dynamic explanation model accommodated the all of the facts seen in controlled seismic sections, but vertical thickening and northeastern shorten of the crust is quite evident and interpretable to a certain extent as the result of continent-continent collision. Simultaneously, weak geophysical signature of the BNS suggests that convergence has been accommodated perhaps partially through pure-shear thickening accompanied by removal of lower crustal material by lateral escape. Recent years the result of Moho with -7 km offset and long extend in south-dip angle beneath the east Kunlun orogen and a grand thrust fault at the northern margin of Qilian orogen has attract more attention to action from the northern blocks. The broad lower-velocity area in the upper-middle crust of the Lhasa block was once considered as resulted from partially melted rocks. However the low normal vp/vs ratio and the Moho stepwise rise fail to support significant partial melting in the middle-lower crust of the central-northern Tibetan plateau. Furthermore, the lower-velocity of crust occasionally disappears, and/or local thinned exhibits their non-stationary spatial distribution.

Development and application of rapid rehabilitation system for reconstruction of maxillofacial soft-tissue defects related to war and traumatic injuries

Background: Maxillofacial war injuries usually cause severe facial organ defects and deformities, handicapping the patient's daily activities, even result in a tendency to commit suicide. The application of maxillofacial prosthesis is an alternative to surgery in functional–aesthetic facial reconstruction. Computer aided design and computer aided manufacturing has opened up a new approach to the fabrication of maxillofacial prosthesis. An intelligentized rapid simulative design and manufacture system for prosthesis was developed to facilitate the prosthesis fabrication procedure.Methods: Maxillofacial prosthesis rapid simulation design and rapid fabrication system consists of three components: digital impression, intelligentized prosthesis designing, and rapid manufacturing. The patients' maxillofacial digital impressions were taken with Structured-light 3D scanner; and then the 3D model of prostheses and their negative molds could be designed in specific software; finally, with the resin molds fabricated by rapid prototyping machine, the prostheses could be produced directly and quickly.Results: Fifteen patients of maxillofacial defect caused by traumatic injuries received prosthesis rehabilitation provided by the established system. The contour of the prostheses coordinated properly with the appearance of the patients, and the uniform-thickness border sealed well to adjacent tissues. All the patients were satisfied with their prostheses.Conclusions: The rapid simulative rehabilitation system of maxillofacial defects has been approaching completion. It could provide advanced technological reservation for the Army in the issue of maxillofacial defect rehabilitation.

Controlling mine pressure by subjecting high-level hard rock strata to ground fracturing

When mining extra-thick coal seams,the main cause of strong ground pressure are the high-level thick and hard strata,but as yet there is no active and effective control technology.This paper proposes the method of subjecting hard roofs to ground fracturing,and physical simulation is used to study the control effect of ground fracturing on the strata structure and energy release.The results show that ground fracturing changes the structural characteristics of the strata and reduces the energy release intensity and the spatial extent of overburden movement,thereby exerting significant control on the ground pressure.The Datong mining area in China is selected as the engineering background.An engineering test was conducted on site by ground horizontal well fracturing,and a 20-m-thick hard rock layer located 110 m vertically above the coal seam was targeted as the fracturing layer.On-site microseismic monitoring shows that the crack propagation length is up to 216 m and the height is up to 50 m.On-site mine pressure monitoring shows that(1)the roadway deformation is reduced to 100 mm,(2)the periodic weighting characteristics of the hydraulic supports are not obvious,and(3)the ground pressure in the working face is controlled significantly,thereby showing that the ground fracturing is successful.Ground fracturing changed the breaking characteristics of the high-level hard strata,thereby helping to ameliorate the stress concentration in the stope and providing an effective control approach for hard rock.

Modified halloysite nanotubes reduce the toxic effects of zearalenone in gestating sows on growth and muscle development of their offsprings

Background： Zearalenone （ZEN） is an estrogenic mycotoxin that is primarily produced by Fusarium fungi and has been proven to affect the reproductive capacity of many species to varying degrees. The present experiment was designed to study the maternal persistent effects of zearalenone toxicity in gestating sows on growth and muscle development of their offsprings, and the alleviation of zearalenone toxicity by modified halloysite nanotubes （MHNTs）. Methods： Eighteen sows were fed with one of three dietary treatments that included the following： （1） a control diet, （2） a contaminated grain diet （with 50 % moldy corn, 2.77 mg/kg ZEN）, and （3） a contaminated grain diet （with 50 % moldy corn, 2.76 mg/kg ZEN） ＋ 1% MHNTs. Each sow was exclusively fed its experimental diets from 35 to 70 d of gestation at a total of 2 kg daily. Muscle samples were collected from six piglets per treatment at birth, weaning and finishing. Results： The results showed that feeding the sows with the ZEN-contaminated diets from 35 to 70 d of gestation decreased the ADG, ADFI and G：F of their offsprings （P 〈 0.05）. The muscle fiber numbers in the newborn, weaning and growing-finishing pigs and the muscle fiber diameters at birth and weaning were also decreased by maternal ZEN exposure （P 〈 0.05）. The expressions of IGF-I, IGF-II, Myf-5 and Mstn at birth and IGF-II, Pax7, Myf-5 and MyoD1 at weaning were altered by feeding gestating sows with ZEN-contaminated diets （P 〈 0.05）. The MHNTs reduced most of the ZEN-induced toxic effects： the ADG and ADFI on growth performance, the muscle fiber numbers at weaning and finishing and the muscle fiber diameters at weaning （P 〈 0.05）. The expression levels of IGF-II and Mstn in newborn piglets and IGF-II and Myf-5 in weaning piglets were also prevented by adding 1% MHNTs （P 〈 0.05）. Conclusions： The present study demonstrated that the offsprings of sows fed with ZEN-contaminated diets from 35 to 70 day of gestation exhibited weakening on growth performance, physiological changes in their muscle fibers and alterations of mRNA expression in their muscle tissues, and also indicated that MHNTs prevented most of the ZEN- induced weakening in the muscle tissues.

Metal phosphides and borides as the catalytic host of sulfur cathode for lithium–sulfur batteries

Lithium−sulfur batteries are one of the most competitive high-energy batteries due to their high theoretical energy density of _(2)600 W·h·kg^(−1).However,their commercialization is limited by poor cycle stability mainly due to the low intrinsic electrical conductivity of sulfur and its discharged products(Li_(2)S_(2)/Li_(2)S),the sluggish reaction kinetics of sulfur cathode,and the“shuttle effect”of soluble intermediate lithi-um polysulfides in ether-based electrolyte.To address these challenges,catalytic hosts have recently been introduced in sulfur cathodes to en-hance the conversion of soluble polysulfides to the final solid products and thus prevent the dissolution and loss of active-sulfur material.In this review,we summarize the recent progress on the use of metal phosphides and borides of different dimensions as the catalytic host of sulfur cathodes and demonstrate the catalytic conversion mechanism of sulfur cathodes with the help of metal phosphides and borides for high-en-ergy and long-life lithium-sulfur batteries.Finally,future outlooks are proposed on developing advanced catalytic host materials to improve battery performance.