In order to study the dynamic and electrical coupling response characteristics of Metal Oxide Semiconductor Controlled Thyristor(MCT)high-voltage switch under the synergic action of mechanical load and high voltage,th...In order to study the dynamic and electrical coupling response characteristics of Metal Oxide Semiconductor Controlled Thyristor(MCT)high-voltage switch under the synergic action of mechanical load and high voltage,the separated Hopkinson pressure bar(SHPB)test system was used to simulate different impact load environments,and combined with the multi-layer high-voltage ceramic capacitor charging and discharging system,the instantaneous electrical signals of MCT high-voltage switch were collected.Combined with numerical simulation and theoretical analysis,the failure mode and stress wave propagation characteristics of MCT high voltage switch were determined.The mechanical and electrical coupling response characteristics and failure mechanism of MCT high voltage switch under dynamic load were revealed from macroscopic and microscopic levels.The results show that the damage modes of MCT high-voltage switches can be divided into non-functional damage,recoverable functional damage,non-recoverable damage and structural damage.Due to the gap between the metal gate and the oxide layer,the insulating oxide layer was charged.After placing for a period of time,the elastic deformation of the metal gate partially recovered and the accumulated charge disappeared,which induced the recoverable functional damage failure of the device.In addition,obvious cracks appeared on both sides of the monocrystalline silicon inside the MCT high-voltage switch,leading to unrecoverable damage of the device.展开更多
In the present study, a rat model of non-traumatic intracerebral hemorrhage was established by type IV collagenase injection into the right globus pallidus. Bax and Bcl-2 expression in tissues surrounding hematomas wa...In the present study, a rat model of non-traumatic intracerebral hemorrhage was established by type IV collagenase injection into the right globus pallidus. Bax and Bcl-2 expression in tissues surrounding hematomas was significantly increased within 14 days after injury, and it then gradually decreased. Vascular endothelial growth factor, Flk-1 and Flt-1 mRNA expression gradually increased over time. After intraperitoneal injection with minocycline, Bax expression was decreased 1 day after intracerebral hemorrhage. Flk-1 and Flt-1 mRNA expression was decreased after minocycline injection, but Bcl-2 expression was increased, and vascular endothelial growth factor mRNA expression was decreased between 4-14 days. These results indicated that protective effects of minocycline on nerve tissues were associated with increased Bcl-2 expression and decreased Bax expression in the early stage after intracerebral hemorrhage. In the late stage, minocycline downregulated vascular endothelial growth factor and its receptor expression to inhibit brain tissue self-repair.展开更多
Mesoporous carbon adsorbents were prepared for the adsorption of Cu(Ⅱ)and Pb(Ⅱ)by calcination with gelatin,chitosan and sucrose as carbon precursor respectively,and magnesium citrate as MgO template precursor under ...Mesoporous carbon adsorbents were prepared for the adsorption of Cu(Ⅱ)and Pb(Ⅱ)by calcination with gelatin,chitosan and sucrose as carbon precursor respectively,and magnesium citrate as MgO template precursor under high temperature argon atmosphere.The effects of the mass ratio of carbon precursor/magnesium citrate and calcination temperature on the adsorption performance of Cu(Ⅱ)and Pb(Ⅱ)ions were investigated.The results showed that the optimum preparation process of adsorbent was obtained as follows:gelatin was carbon precursor,and gelatin and magnesium citrate were calcined at a mass ratio of 5∶5 under argon atmosphere of 600℃for 2 h.The adsorbent exhibited mesostructure with a pore size of about 5.1 nm and a high specific surface area of 783 m^2/g.The as-synthesized adsorbent exhibited high adsorption capacity for Cu(Ⅱ)(8.3 mg/g)and Pb(Ⅱ)(28 mg/g).展开更多
For the realization of retina-inspired neuromorphic visual systems which simulate basic functions of human visual systems,optoelectronic synapses capable of combining perceiving,processing,and memorizing in a single d...For the realization of retina-inspired neuromorphic visual systems which simulate basic functions of human visual systems,optoelectronic synapses capable of combining perceiving,processing,and memorizing in a single device have attracted immense interests.Here,optoelectronic synaptic transistors based on tris(2-phenylpyridine)iridium(Ir(ppy)_(3))and poly(3,3-didodecylquarterthiophene)(PQT-12)heterojunction structure are presented.The organic heterojunction serves as a basis for distinctive synaptic characteristics under different wavelengths of light.Furthermore,synaptic transistor arrays are fabricated to demonstrate their optical perception efficiency and color recognition capability under multiple illuminating conditions.The wavelength-tunability of synaptic behaviors further enables the mimicry of mood-modulated visual learning and memorizing processes of humans.More significantly,the computational dynamics of neurons of synaptic outputs including associated learning and optical logic functions can be successfully demonstrated on the presented devices.This work may locate the stage for future studies on optoelectronic synaptic devices toward the implementation of artificial visual systems.展开更多
2D polymers(2DPs)have attracted increasing interests in sensors,catalysis,and gas storage applications.Furthermore,2DPs with unique band structure and tunable photophysical properties also have immense potential for a...2D polymers(2DPs)have attracted increasing interests in sensors,catalysis,and gas storage applications.Furthermore,2DPs with unique band structure and tunable photophysical properties also have immense potential for application in photonic neuromorphic computing.Here,photonic synaptic transistors based on 2DPs as the light-tunable charge-trapping medium are developed for the first time.The resulted organic transistors can successfully emulate common synaptic functions,including excitatory postsynaptic current,pair-pulse facilitation,the transition of short-term memory to long-term memory,and dynamic filtering.Benefitting from the high photosensitivity of the 2DP,the devices can be operated under a low operating voltage of0.1 V,and achieve an ultralow energy consumption of~0.29 pJ per event.In addition,the heterostructure formed between the 2DP and organic semiconductor enables spectrum-dependent synaptic responses,which facilitates the simulation of visual learning and memory processes in distinct emotional states.The underlying mechanism of spectrum-dependent synaptic-like behaviors is systematically validated with in situ atomic force microscopy based electrical techniques.The spectrum-enabled tunability of synaptic behaviors further promotes the realization of optical logic functions and associative learning.This work inspires the new application of 2DPs in photonic synapses for future neuromorphic computing.展开更多
A microcavity laser based on evanescent-wave-coupled gain is formed using a silica fiber with a diameter of 125 μm in a rhodamine 6G ethanol solution. When the fiber is sticking to the cuvette wall by capillary force...A microcavity laser based on evanescent-wave-coupled gain is formed using a silica fiber with a diameter of 125 μm in a rhodamine 6G ethanol solution. When the fiber is sticking to the cuvette wall by capillary force,using the excitation of a 532 nm nanosecond pulsed laser, single-mode laser emission is observed. While increasing the distance between the fiber and the cuvette wall, the typical multi-peak whispering-gallery-mode(WGM)laser emission can also be demonstrated. On the other hand, while increasing the refractive index of the solution by mixing ethanol and ethylene glycol with different ratios as a solvent, the single-mode emission would evolve to multi-peak WGM laser emission controllably.展开更多
To the Editor:Lung ultrasound(LUS)may be a promising technique to assess lung injury from coronavirus disease 2019(COVID-19).However,the LUS characteristics and their assessment value have not been well described.We a...To the Editor:Lung ultrasound(LUS)may be a promising technique to assess lung injury from coronavirus disease 2019(COVID-19).However,the LUS characteristics and their assessment value have not been well described.We aimed to explore the LUS characteristics and their assessment value in COVID-19 patients with different levels of disease severity.展开更多
基金Youth Talent Project of Basic Scientific Research Project of Liaoning Province Education Department(Grant No.LJKZ0270)Youth Project of Basic Scientific Research Project of Liaoning Province Education Department(Grant No.LJKQZ2021055).
文摘In order to study the dynamic and electrical coupling response characteristics of Metal Oxide Semiconductor Controlled Thyristor(MCT)high-voltage switch under the synergic action of mechanical load and high voltage,the separated Hopkinson pressure bar(SHPB)test system was used to simulate different impact load environments,and combined with the multi-layer high-voltage ceramic capacitor charging and discharging system,the instantaneous electrical signals of MCT high-voltage switch were collected.Combined with numerical simulation and theoretical analysis,the failure mode and stress wave propagation characteristics of MCT high voltage switch were determined.The mechanical and electrical coupling response characteristics and failure mechanism of MCT high voltage switch under dynamic load were revealed from macroscopic and microscopic levels.The results show that the damage modes of MCT high-voltage switches can be divided into non-functional damage,recoverable functional damage,non-recoverable damage and structural damage.Due to the gap between the metal gate and the oxide layer,the insulating oxide layer was charged.After placing for a period of time,the elastic deformation of the metal gate partially recovered and the accumulated charge disappeared,which induced the recoverable functional damage failure of the device.In addition,obvious cracks appeared on both sides of the monocrystalline silicon inside the MCT high-voltage switch,leading to unrecoverable damage of the device.
基金supported by the National Natural Science Foundation of China (Repair of brain injury in early stage using choroid plexus cell transplantation), No. 30973099
文摘In the present study, a rat model of non-traumatic intracerebral hemorrhage was established by type IV collagenase injection into the right globus pallidus. Bax and Bcl-2 expression in tissues surrounding hematomas was significantly increased within 14 days after injury, and it then gradually decreased. Vascular endothelial growth factor, Flk-1 and Flt-1 mRNA expression gradually increased over time. After intraperitoneal injection with minocycline, Bax expression was decreased 1 day after intracerebral hemorrhage. Flk-1 and Flt-1 mRNA expression was decreased after minocycline injection, but Bcl-2 expression was increased, and vascular endothelial growth factor mRNA expression was decreased between 4-14 days. These results indicated that protective effects of minocycline on nerve tissues were associated with increased Bcl-2 expression and decreased Bax expression in the early stage after intracerebral hemorrhage. In the late stage, minocycline downregulated vascular endothelial growth factor and its receptor expression to inhibit brain tissue self-repair.
基金Supported by Natural Science Foundation of Tibet Autonomous Region(XZ2017ZRG-03)High-level Training Programs for Postgraduates of Tibet University(2017-GSP-018)+1 种基金Tibet University 2018,2019 Central Financial Support Special Funds for Local Colleges and Universities([2018]54,[2019]19)High-level Personnel Training Programs of Tibet University(010341)
文摘Mesoporous carbon adsorbents were prepared for the adsorption of Cu(Ⅱ)and Pb(Ⅱ)by calcination with gelatin,chitosan and sucrose as carbon precursor respectively,and magnesium citrate as MgO template precursor under high temperature argon atmosphere.The effects of the mass ratio of carbon precursor/magnesium citrate and calcination temperature on the adsorption performance of Cu(Ⅱ)and Pb(Ⅱ)ions were investigated.The results showed that the optimum preparation process of adsorbent was obtained as follows:gelatin was carbon precursor,and gelatin and magnesium citrate were calcined at a mass ratio of 5∶5 under argon atmosphere of 600℃for 2 h.The adsorbent exhibited mesostructure with a pore size of about 5.1 nm and a high specific surface area of 783 m^2/g.The as-synthesized adsorbent exhibited high adsorption capacity for Cu(Ⅱ)(8.3 mg/g)and Pb(Ⅱ)(28 mg/g).
基金supported by the National Key Research and Development Program of China(2017YFA0103904)the National Natural Science Foundation of China(61822405,62074111)+3 种基金the Science&Technology Foundation of Shanghai(19JC1412402,20JC1415600)Shuguang Program supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission(18SG20)Beijing National Laboratory for Molecular Sciences(BNLMS201904)the support of the Fundamental Research Funds for the Central Universities.
文摘For the realization of retina-inspired neuromorphic visual systems which simulate basic functions of human visual systems,optoelectronic synapses capable of combining perceiving,processing,and memorizing in a single device have attracted immense interests.Here,optoelectronic synaptic transistors based on tris(2-phenylpyridine)iridium(Ir(ppy)_(3))and poly(3,3-didodecylquarterthiophene)(PQT-12)heterojunction structure are presented.The organic heterojunction serves as a basis for distinctive synaptic characteristics under different wavelengths of light.Furthermore,synaptic transistor arrays are fabricated to demonstrate their optical perception efficiency and color recognition capability under multiple illuminating conditions.The wavelength-tunability of synaptic behaviors further enables the mimicry of mood-modulated visual learning and memorizing processes of humans.More significantly,the computational dynamics of neurons of synaptic outputs including associated learning and optical logic functions can be successfully demonstrated on the presented devices.This work may locate the stage for future studies on optoelectronic synaptic devices toward the implementation of artificial visual systems.
基金Beijing National Laboratory for Molecular Sciences,Grant/Award Number:BNLMS201904Fundamental Research Funds for the Central Universities+4 种基金Large Scale Instrument Test Funds of Tongji University,Grant/Award Number:2021GX002National Key Research and Development Program of China,Grant/Award Number:2017YFA0103904National Natural Science Foundation of China,Grant/Award Numbers:61822405,62074111Science and Technology Foundation of Shanghai,Grant/Award Numbers:19JC1412402,20JC1415600Shuguang Program supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission,Grant/Award Number:18SG20。
文摘2D polymers(2DPs)have attracted increasing interests in sensors,catalysis,and gas storage applications.Furthermore,2DPs with unique band structure and tunable photophysical properties also have immense potential for application in photonic neuromorphic computing.Here,photonic synaptic transistors based on 2DPs as the light-tunable charge-trapping medium are developed for the first time.The resulted organic transistors can successfully emulate common synaptic functions,including excitatory postsynaptic current,pair-pulse facilitation,the transition of short-term memory to long-term memory,and dynamic filtering.Benefitting from the high photosensitivity of the 2DP,the devices can be operated under a low operating voltage of0.1 V,and achieve an ultralow energy consumption of~0.29 pJ per event.In addition,the heterostructure formed between the 2DP and organic semiconductor enables spectrum-dependent synaptic responses,which facilitates the simulation of visual learning and memory processes in distinct emotional states.The underlying mechanism of spectrum-dependent synaptic-like behaviors is systematically validated with in situ atomic force microscopy based electrical techniques.The spectrum-enabled tunability of synaptic behaviors further promotes the realization of optical logic functions and associative learning.This work inspires the new application of 2DPs in photonic synapses for future neuromorphic computing.
基金National Natural Science Foundation of China(NSFC)(61574078,61627802,61704063)Fundamental Research Funds for the Central Universities(30915011202,30916014112-002)Project of Jiangsu Laboratory of Lake Environment Remote Sensing Technologies(JSLERS-2017-001)
文摘A microcavity laser based on evanescent-wave-coupled gain is formed using a silica fiber with a diameter of 125 μm in a rhodamine 6G ethanol solution. When the fiber is sticking to the cuvette wall by capillary force,using the excitation of a 532 nm nanosecond pulsed laser, single-mode laser emission is observed. While increasing the distance between the fiber and the cuvette wall, the typical multi-peak whispering-gallery-mode(WGM)laser emission can also be demonstrated. On the other hand, while increasing the refractive index of the solution by mixing ethanol and ethylene glycol with different ratios as a solvent, the single-mode emission would evolve to multi-peak WGM laser emission controllably.
基金The study was supported by the grants from Wu Jieping Medical Foundation(Nos.320.6750.18037,320.6750.18068)Guangdong Medical Research Foundation(No.A2020300)。
文摘To the Editor:Lung ultrasound(LUS)may be a promising technique to assess lung injury from coronavirus disease 2019(COVID-19).However,the LUS characteristics and their assessment value have not been well described.We aimed to explore the LUS characteristics and their assessment value in COVID-19 patients with different levels of disease severity.