Introduction The tuber of Ophiopogon japonicus ( L. f) Ker- Gawl, which is a Chinese traditional medicine named "maidong" have been recorded to have various medical functions for curing cardiovascular diseases an...Introduction The tuber of Ophiopogon japonicus ( L. f) Ker- Gawl, which is a Chinese traditional medicine named "maidong" have been recorded to have various medical functions for curing cardiovascular diseases and bacterial infections, especially heart diseases. Phytochemical studies on this plant were reported previously. In search of new and bioactive components from Chinese traditional medicines, the tubers of Ophiopogon japonicus have been investigated in this study. The present paper article covers the isolation and structure elucidation of a new furospirostanol saponin, namely, Ophiofurospiside B (compound 1 ) and two known steroidal saponins ( compounds 2 and 3).展开更多
Two new furostanol glucosides, named tribufurosides G and H, were isolated from Tribulus terrestris L. The structures of the two new furostanol glucosides were elucidated as 26-O-β-D-glucopyranosyl-(25R)-5α-furost...Two new furostanol glucosides, named tribufurosides G and H, were isolated from Tribulus terrestris L. The structures of the two new furostanol glucosides were elucidated as 26-O-β-D-glucopyranosyl-(25R)-5α-furost12-one-3β,22α,26-tetraol-3-O-β-D-glucopyranosyl-( 1→2 )-β-D-glucopyranosyl-( 1→4 )-β-D-galactopyranoside( 1 ) and 26-O-β-D-glucopyranosyl-(25S)-5 α- 12-one-2 α,3,8,22 α,26-tetraol-3 -O-β-D-glucopyranosyl-( 1 → 2 )-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside(2) by 1 D, 2D NMR techniques, ESI-MS analysis as well as chemical methods.展开更多
基金Supported by Program for Changjiang ScholarsInnovative Research Team in University(No.IRT0413).
文摘Introduction The tuber of Ophiopogon japonicus ( L. f) Ker- Gawl, which is a Chinese traditional medicine named "maidong" have been recorded to have various medical functions for curing cardiovascular diseases and bacterial infections, especially heart diseases. Phytochemical studies on this plant were reported previously. In search of new and bioactive components from Chinese traditional medicines, the tubers of Ophiopogon japonicus have been investigated in this study. The present paper article covers the isolation and structure elucidation of a new furospirostanol saponin, namely, Ophiofurospiside B (compound 1 ) and two known steroidal saponins ( compounds 2 and 3).
基金Supported by the National Natural Science Foundation of China(No.30873357)the Program for New Century Excellent Talents in University of China(No.NCET-08-0746)
文摘Two new furostanol glucosides, named tribufurosides G and H, were isolated from Tribulus terrestris L. The structures of the two new furostanol glucosides were elucidated as 26-O-β-D-glucopyranosyl-(25R)-5α-furost12-one-3β,22α,26-tetraol-3-O-β-D-glucopyranosyl-( 1→2 )-β-D-glucopyranosyl-( 1→4 )-β-D-galactopyranoside( 1 ) and 26-O-β-D-glucopyranosyl-(25S)-5 α- 12-one-2 α,3,8,22 α,26-tetraol-3 -O-β-D-glucopyranosyl-( 1 → 2 )-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside(2) by 1 D, 2D NMR techniques, ESI-MS analysis as well as chemical methods.