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A New Furospirostanol Saponin,Ophiofurospiside B from Ophiopogon japonicus(Thunb.) Ker-Gawl 被引量:1
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作者 XU Tun-hai XU Ya-juan +6 位作者 CHEN Ping HAN Dong ZHAO Hong-feng si yun-shan XU Dong-ming LI Yu NIU Jian-Zhao 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2007年第6期742-744,共3页
Introduction The tuber of Ophiopogon japonicus ( L. f) Ker- Gawl, which is a Chinese traditional medicine named "maidong" have been recorded to have various medical functions for curing cardiovascular diseases an... Introduction The tuber of Ophiopogon japonicus ( L. f) Ker- Gawl, which is a Chinese traditional medicine named "maidong" have been recorded to have various medical functions for curing cardiovascular diseases and bacterial infections, especially heart diseases. Phytochemical studies on this plant were reported previously. In search of new and bioactive components from Chinese traditional medicines, the tubers of Ophiopogon japonicus have been investigated in this study. The present paper article covers the isolation and structure elucidation of a new furospirostanol saponin, namely, Ophiofurospiside B (compound 1 ) and two known steroidal saponins ( compounds 2 and 3). 展开更多
关键词 Ophiopogon japonicus (L. f) Ker-Gawl Furospirostanol saponin Ophiofurospiside B
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正交试验法优选散痛风凝胶膏贴剂中总黄酮类成分提取工艺 被引量:2
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作者 司云珊 翟宏业 +2 位作者 王玉 马力 耿琍 《中国处方药》 2020年第12期29-30,共2页
目的优化散痛风凝胶膏贴剂中总黄酮类成分提取工艺。方法紫外-可见分光光度法测定散痛风凝胶膏贴剂总黄酮质量分数,选用L_9(3~4)正交表,以乙醇体积分数、乙醇用量、提取时间和提取次数为考察因素,分别以总黄酮提取率为考察指标,优化散... 目的优化散痛风凝胶膏贴剂中总黄酮类成分提取工艺。方法紫外-可见分光光度法测定散痛风凝胶膏贴剂总黄酮质量分数,选用L_9(3~4)正交表,以乙醇体积分数、乙醇用量、提取时间和提取次数为考察因素,分别以总黄酮提取率为考察指标,优化散痛风凝胶膏贴剂提取工艺参数。结果总黄酮最佳提取工艺为10倍量60%乙醇,回流提取2次,每次1.5 h。结论优化的工艺简单、稳定、可行,重复性好,可分别用于散痛风贴膏剂中总黄酮的提取。 展开更多
关键词 散痛风凝胶膏贴剂 总黄酮 提取工艺 正交试验
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正交试验法优化E视力眼贴基质
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作者 司云珊 翟万邦 《中国处方药》 2021年第9期42-44,共3页
目的优化E视力眼贴凝胶贴的基质处方配比。方法在单因素试验基础上,以粘附性、赋形性、涂展性、透布性、均匀性、膜残留量等感官指标,初粘力等物理指标为考察指标综合评分,在单因素试验考察辅料种类及部分辅料用量的基础上,用Oea-31s正... 目的优化E视力眼贴凝胶贴的基质处方配比。方法在单因素试验基础上,以粘附性、赋形性、涂展性、透布性、均匀性、膜残留量等感官指标,初粘力等物理指标为考察指标综合评分,在单因素试验考察辅料种类及部分辅料用量的基础上,用Oea-31s正交法对凝胶贴基质处方配比工艺进行优化筛选,得到最佳工艺参数,为制剂提供科学可靠的依据。结果甘油-NOVETAC VP20-NOVETAC P55N-甘羟铝-NOVEPHIL 520-中药粉-去离子水(30∶5.5∶1.0∶0.10∶20∶15∶55)为凝胶贴基质处方最佳配比。结论该方法简便、筛选率高,可用于制备E视力眼贴。 展开更多
关键词 E视力眼贴 基质 处方配比
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Two New Furostanol Saponins from Tribulus Terrestris L. 被引量:2
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作者 XU Ya-juan XU Tun-hai +2 位作者 XIE Sheng-xu si yun-shan XU Dong-ming 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2010年第1期46-49,共4页
Two new furostanol glucosides, named tribufurosides G and H, were isolated from Tribulus terrestris L. The structures of the two new furostanol glucosides were elucidated as 26-O-β-D-glucopyranosyl-(25R)-5α-furost... Two new furostanol glucosides, named tribufurosides G and H, were isolated from Tribulus terrestris L. The structures of the two new furostanol glucosides were elucidated as 26-O-β-D-glucopyranosyl-(25R)-5α-furost12-one-3β,22α,26-tetraol-3-O-β-D-glucopyranosyl-( 1→2 )-β-D-glucopyranosyl-( 1→4 )-β-D-galactopyranoside( 1 ) and 26-O-β-D-glucopyranosyl-(25S)-5 α- 12-one-2 α,3,8,22 α,26-tetraol-3 -O-β-D-glucopyranosyl-( 1 → 2 )-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside(2) by 1 D, 2D NMR techniques, ESI-MS analysis as well as chemical methods. 展开更多
关键词 Tribulus terrestris L. Furostanol saponin Tribufurosides G and H
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