BACKGROUND Several bibliometric analyses have been carried out to identify research hotspots and trends in nonalcoholic fatty liver disease(NAFLD)research.Nonetheless,there are still significant knowledge gaps that mu...BACKGROUND Several bibliometric analyses have been carried out to identify research hotspots and trends in nonalcoholic fatty liver disease(NAFLD)research.Nonetheless,there are still significant knowledge gaps that must be filled to advance our understanding of and ability to treat NAFLD.AIM To evaluate,through bibliometric and visual analysis,the current status of related research,related research frontiers,and the developmental trends in the field of diet and NAFLD.METHODS We retrieved publications about diet and NAFLD published between 1987 and 2022 from Scopus.Next,we used VOSviewer 1.6.20 to perform bibliometric analysis and visualization.RESULTS We found a total of 1905 studies,including 1637(85.93%)original articles and 195(10.24%)reviews,focused on the examination of NAFLD and its correlation with diet that were published between 1987 and 2022.Among the remaining five types of documents,38 were letters,notes,editorials,meeting minutes,or brief surveys,representing 1.99%of the total documents.The countries with the most publications on this topic were China(n=539;28.29%),followed by the United States(n=379;19.90%),Japan(n=133;6.98%),and South Korea(n=127;6.6%).According to the citation analysis,the retrieved papers were cited an average of 32.3 times and had an h-index of 106,with 61014 total citations.The two main clusters on the map included those related to:(1)Inflammation and oxidative stress;and(2)Dietary interventions for NAFLD.CONCLUSION This was the first study to use data taken from Scopus to visualize network mapping in a novel bibliometric analysis of studies focused on diet and NAFLD.After 2017,the two domains that received the most attention were“dietary interventions for NAFL”’and“‘inflammation and oxidative stress implicated in NAFLD and its correlation with diet.”We believe that this study provides important information for academics,dietitians,and doctors,and that additional research on dietary interventions and NAFLD is warranted.展开更多
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this...BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and NAFLD.AIM To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and IR.METHODS This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to 2022.The search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and NAFLD.VOSviewer software was used to visualize research trends,collaborations,and key thematic areas.The analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited references.RESULTS This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and 2022.The search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)reviews.The most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflammatory and high-fat diet impacts on NAFLD”.CONCLUSION This is the first bibliometric analysis to examine the relationship between IR and NAFLD.In response to the escalating global health challenge of NAFLD,this research highlights an urgent need for a better understanding of this condition and for the development of intervention strategies.Policymakers need to prioritize and address the increasing prevalence of NAFLD.展开更多
BACKGROUND The global spread of severe acute respiratory syndrome coronavirus 2,responsible for coronavirus disease 2019(COVID-19),poses a significant risk to public health.Beyond the respiratory issues initially asso...BACKGROUND The global spread of severe acute respiratory syndrome coronavirus 2,responsible for coronavirus disease 2019(COVID-19),poses a significant risk to public health.Beyond the respiratory issues initially associated with the condition,severe cases of COVID-19 can also lead to complications in other organs,including the liver.Patients with severe COVID-19 may exhibit various clinical signs of liver dysfunction,ranging from minor elevations in liver enzymes without symptoms to more serious cases of impaired liver function.Liver damage is more commonly observed in patients with severe or critical forms of the disease.AIM To present the research landscape on COVID-19 and liver dysfunction while also offering valuable insights into the prominent areas of interest within this particular domain.METHODS On 18 February 2023,Scopus was utilised to conduct a comprehensive exploration of the relationship between COVID-19 and the liver dysfunction.The investigation encompassed the period from 1 January 2020 to 31 December 2022.Primary sources were meticulously examined and organised in a Microsoft Excel 2013 spreadsheet,categorised by journal,institution,funding agency,country and citation type.VOSviewer version 1.6.18 was employed to explore the prominent topics and knowledge network related to the subject.RESULTS There were 2336 publications on COVID-19 and liver dysfunction analysed in this study,of which 558 were published in 2020,891 in 2021 and 887 in 2022.Researchers from 111 different countries participated in the retrieved documents.The United States contributed the most studies,with 497 documents,representing 21.28%of the total,followed by China with 393 documents(16.82%)and Italy with 255 documents(10.92%).In the context of research related to COVID-19 and the liver,co-occurrence analysis identified three distinct clusters of topics:(1)‘COVID-19 vaccines in liver transplant recipients’;(2)‘liver function tests as a predictor of the severity and clinical outcomes in hospitalised patients’;and(3)‘care of patients with liver disease during the COVID-19 pandemic’.CONCLUSION This bibliometric study provides a comprehensive overview of liver-related publications in COVID-19 research over the past 3 years.This study highlights the significant contributions of high-income nations,particularly the United States,China,and Italy,to the production of liver-related scholarly literature in this field.Most of the articles focused on liver dysfunction in patients with COVID-19 and the implications of the virus for gastroenterologists and hepatologists.展开更多
BACKGROUND Crohn’s disease represents a challenge for patients concerned with the modified diet regimen as well as practitioners who seek the best nutritional therapy.Crohn’s disease can alter the body’s ability to...BACKGROUND Crohn’s disease represents a challenge for patients concerned with the modified diet regimen as well as practitioners who seek the best nutritional therapy.Crohn’s disease can alter the body’s ability to digest food and to absorb nutrients,resulting in severe vitamin deficiencies,malnutrition and sometimes lifethreatening complications.However,a comprehensive bibliometric analysis is lacking to map the current links between nutrition and Crohn’s disease in terms of the number of citations,geographic distribution and growth trends of publications.AIM To introduce the current state of research as well as hotspots in the field of nutrition and Crohn’s disease from a bibliometric standpoint.METHODS We searched the Scopus database and selected the relevant literature on nutrition and Crohn’s disease that met the inclusion criteria.We analyzed the publication trends and research hotspots by using video object segmentation viewer software.RESULTS We included 1237 publications.The number of documents published each year has increased steadily.The United States and the University of Otago,Christchurch,have had the highest productivity,with 208(16.81%)and 29(2.34%)documents,respectively.The“role of exclusive enteral nutrition for complicated Crohn’s disease”and“manipulation of the gut microbiota as a key target for Crohn’s disease”were the major research areas in 2016-2021,and they could be extensively investigated in the future.Meanwhile,research on“malnutrition in patients with Crohn’s disease”appeared to be an area that attracted more research attention before 2016.CONCLUSION This is the first bibliometric analysis to map the knowledge structure and trends regarding nutrition in Crohn’s disease research over the past two decades.The results provide a comprehensive summary and identification of the frontiers of nutrition and Crohn’s disease-related research,which may be used as a resource by researchers in the field.展开更多
BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the mic...BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the microbiome plays a key role in the development and normal functioning of the gut–brain axis.AIM To facilitate the identification of specific areas of focus that may be of relevance to future research. This study represents a bibliometric analysis of the literature pertaining to the microbiome in IBS to understand the development of this field.METHODS The data used in our bibliometric analysis were retrieved from the Scopus database. The terms related to IBS and microbiome were searched in titles or abstracts within the period of 2000–2019. VOSviewer software was used for data visualization.RESULTS A total of 13055 documents related to IBS were retrieved at the global level. There were 1872 scientific publications focused on the microbiome in IBS. There was a strong positive correlation between publication productivity related to IBS in all fields and productivity related to the microbiome in IBS(r = 0.951, P < 0.001). The United States was the most prolific country with 449(24%) publications, followed by the United Kingdom(n = 176, 9.4%), China(n = 154, 8.2%), and Italy(n = 151, 8.1%). The h-index for all retrieved publications related to the microbiome in IBS was 138. The hot topics were stratified into four clusters:(1) The gut–brain axis related to IBS;(2) Clinical trials related to IBS and the microbiome;(3) Drugmediated manipulation of the gut microbiome;and(4) The role of the altered composition of intestinal microbiota in IBS prevention.CONCLUSION This is the first study to evaluate and quantify global research productivity pertaining to the microbiome in IBS. The number of publications regarding the gut microbiota in IBS has continuously grown since 2013. This finding suggests that the future outlook for interventions targeting the gut microbiota in IBS remains promising.展开更多
BACKGROUND Clostridioides(Clostridium)difficile(C.difficile)is still the most common cause of healthcare-associated diarrhoea and is increasing in prevalence as a communityacquired infection.In addition,the emergence ...BACKGROUND Clostridioides(Clostridium)difficile(C.difficile)is still the most common cause of healthcare-associated diarrhoea and is increasing in prevalence as a communityacquired infection.In addition,the emergence of antibiotic resistance in C.difficile can increase the likelihood of the disease developing and/or spreading.AIM To provide an up-to-date picture of the trends in publications related to C.difficile infection,together with specific insights into hot-button issues in this field.METHODS Publications on C.difficile infections in the field of microbiology between 2001 and 2020 were identified from the Scopus database and Reference Citation Analysis.Bibliometric indicators were determined,including the number and type of publications,countries,affiliations,funding agencies,journals and citation patterns.VOSviewer was used to determine research areas and hot-button issues by identifying recurring terms with a high relative occurrence in the title and abstract.RESULTS A total of 8127 documents on‘C.difficile-associated diarrhoea’published between 2001 and 2020 were retrieved from the Scopus database.In the last decade,there has been a significant almost fourfold increase in the number of published papers on this topic.The United States was among the countries(44.11%)with the most publications,and the most involved institution was the University of Leeds in the United Kingdom(2.50%).Three clusters of research were identified and included‘illness spectrum and severity,as well as the signs,symptoms and clinical pathogenesis of C.difficile’;‘laboratory diagnosis and characterization of C.difficile’and‘risk factors for C.difficile infection’.CONCLUSION This study contains the most up-to-date and comprehensive data ever compiled in this field.More international research and cross-institutional collaborations are needed to address more global C.difficile concerns and to benefit from greater sharing of expertise,which will result in higher quality or more effective studies in the future.Promising research avenues in the near future may draw the attention of relevant scientists and funding organizations and open up novel C.difficile infection–based diagnosis and treatment approaches.展开更多
BACKGROUND One of the most popular bariatric procedures is sleeve gastrectomy,and it has become significantly more common in recent years.AIM To evaluate the research activity in sleeve gastrectomy over the last two d...BACKGROUND One of the most popular bariatric procedures is sleeve gastrectomy,and it has become significantly more common in recent years.AIM To evaluate the research activity in sleeve gastrectomy over the last two decades,and to visualize the hot spots and emerging trends in this type of bariatric surgeryusing bibliometric methods.METHODS The Scopus database was used to search for publications related to sleeve gastrectomy.The retrieved publications were reviewed in terms of year of publication,type of study,country of origin,institutions,journals,and citation patterns by using descriptive analysis.Collaboration network and term cooccurrence analysis were visualized by using VOSviewer software.RESULTS The search strategy yielded a total of 6508 publications on sleeve gastrectomy from 2001 to 2020.As regards the document type,the majority were articles(n=5230;80.36%),followed by reviews(n=544;8.36%).The top three countries are the United States,with 1983 publications(30.47%),followed by France(600;9.22%)and Italy(417;6.71%).The most cited publication was published in 2012 by Schauer et al in the New England Journal of Medicine(n=1435 citations).This publication found that weight loss was greater in the sleeve gastrectomy group than in the medical therapy group.Furthermore,this study demonstrated that 12 mo of medical therapy plus bariatric surgery greatly improved glycemic regulation in obese patients with uncontrolled type 2 diabetes compared with medical therapy alone.The focus of the current literature on sleeve gastrectomy was directed toward several themes such as morbidity and potential complications,the complexity of the procedure and different surgical approaches,and diabetes and body mass index in correlation to sleeve gastrectomy.CONCLUSION The number of sleeve gastrectomy publications has gradually grown over the last 20 years.This bibliometric analysis could help researchers better understand the knowledge base and research frontiers surrounding sleeve gastrectomy.In addition,future studies may focus on emerging research hotspots.展开更多
BACKGROUND Nutrition is a significant modifiable element that influences the composition of the gastrointestinal microbiota,implying the possibility of therapeutic diet methods that manipulate the composition and dive...BACKGROUND Nutrition is a significant modifiable element that influences the composition of the gastrointestinal microbiota,implying the possibility of therapeutic diet methods that manipulate the composition and diversity of the microbial.AIM To overview research papers on nutrition and gut microbiota and determines the hotspots in this field at the global level.METHODS Scopus and Reference Citation Analysis were used to construct a bibliometric technique.It was decided to create bibliometric indicators and mapping as in most previous studies.2012 through 2021 served as the study's timeframe.RESULTS A total of 5378 documents from the Scopus database were selected for analysis.Of all retrieved studies,78.52%were research papers(n=4223),followed by reviews(n=820;15.25%).China ranked first with a total number of articles of 1634(30.38%),followed by the United States in second place with a total number of articles of 1307(24.3%).In the last decade,emerging hotspots for gut microbiota and nutrition research included"gut microbiota metabolism and interaction with dietary components","connection between the gut microbiota and weight gain",and"the influence of high-fat diet and gut microbiota on metabolic disorders".CONCLUSION This is the first thorough bibliometric analysis of nutrition and gut microbiota publications conducted on a global level.Investigation of the association between nutrition/diet and the gut microbiota is still in its infancy and will be expanded in the future.However,according to recent trends,the"effect of gut microbiota and high-fat diet on metabolic disorders"will be an increasing concern in the future.展开更多
BACKGROUND Recently,neonatal abstinence syndrome(NAS)emerged as a significant global concern with a dramatic increase in healthcare expenditures.The incidence of the NAS has increased notably in the past decade and em...BACKGROUND Recently,neonatal abstinence syndrome(NAS)emerged as a significant global concern with a dramatic increase in healthcare expenditures.The incidence of the NAS has increased notably in the past decade and emergence as a global public health problem.AIM To evaluate the development and trend of global NAS research from 1958 to 2019 by bibliometric analysis.METHODS Analyzed aspects included publication output per year,language,document types,journals,countries/territories,h-index,authors,and top research priorities.The VOSviewer was used to determine the top research priorities,and trends,and to present bibliometric networks concerning various dimensions,such as coauthorship,authors,and countries.RESULTS A total of 1738 articles were retrieved in the Scopus database from 1958 to 2019.It was found that the great majority of the total NAS documents(n=1295)were original articles followed by reviews(n=268)and letters(n=48).The most productive countries in the NAS field were the United States(n=833),Canada(n=112),the United Kingdom(n=111),and Germany(n=77).Treatment and hospital outcomes in NAS,evidence-based nurse-driven interventions for the care of newborns with NAS,and a systematic reviews and network meta-analysis for therapeutic approaches of NAS were found in recent years(after 2010),compared with terms such as pathophysiology,mechanisms of NAS,and signs and symptoms in the early years.CONCLUSION Treatment and pediatric outcomes and the effectiveness of pharmacological treatment may be frontiers in the NAS field,and continued efforts from researchers are needed in those topics.展开更多
BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global health.In individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and ...BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global health.In individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and increased mortality.AIM To identify research hotspots and prospects,we used bibliometrics to examine the global production of COVID-19 literature published in the field of oncology.METHODS Data on publication output were identified based on the Scopus database between January 1,2020,and June 21,2022.This study used VOSviewer to analyze collaboration networks among countries and assess the terms most often used in the titles and abstracts of retrieved publications to determine research hotspots linked to cancer and COVID-19.The Impact Index Per Article for the top 10 high-cited papers collected from Reference Citation Analysis(RCA)are presented.RESULTS A total of 7015 publications were retrieved from the database.The United States published the greatest number of articles(2025;28.87%),followed by Italy(964;13.74%),the United Kingdom(839;11.96%),and China(538;7.67%).The University of Texas MD Anderson Cancer Center(n=205,2.92%)ranked first,followed by the Memorial Sloan-Kettering Cancer Center(n=176,2.51%).The European Journal of Cancer(n=106,1.51%)ranked first,followed by the Frontiers in Oncology(n=104,1.48%),Cancers(n=102,1.45%),and Pediatric Blood and Cancer(n=95;1.35%).The hot topics were stratified into“cancer care management during the COVID-19 pandemic”;and“COVID-19 vaccines in cancer patients”.CONCLUSION This is the first bibliometric analysis to determine the present state and upcoming hot themes related to cancer and COVID-19 and vice versa using VOSviewer during the early stages of the pandemic.The emergence of hot themes related to cancer and COVID-19 may aid researchers in identifying new research areas in this field.展开更多
BACKGROUND Binge-eating disorder(BED)is a clinical syndrome and is considered the most common type of eating disorder.However,our understanding of the global performance and progress of BED research is limited.AIM To ...BACKGROUND Binge-eating disorder(BED)is a clinical syndrome and is considered the most common type of eating disorder.However,our understanding of the global performance and progress of BED research is limited.AIM To describe and perform a bibliometric analysis of the state of BED research.METHODS The term‘Binge eating’was searched in the title throughout the previous year’s up to December 31,2020.We searched the Scopus and Reference Citation Analysis for publications on Binge eating.The VOSviewer software version 1.6.17 was used to produce the network visualization map of the most frequent author,collaborative relationships between countries/regions,and to determine the hotspots related to binge eating research.In addition,conventional bibliometric indicators were generated.RESULTS The search strategy found 2713 total articles and an average of 62 articles per year.Among them,‘Article’represented 82.49%of the publications(n=2238 articles)and was the most frequent type,followed by reviews(n=243;8.96%).The number of publications increased steadily during the last decade of the study period.One hundred and thirty-two countries contributed to binge eating research,with 1495(55.11%)articles published in the United States,followed by Italy with 256(9.44%),the United Kingdom with 183(6.75%),and Germany with 182(6.71%).Currently,the main hot topics related to BED are‘type of treatment and management and treatment provided to BED”;“processes and pathways to binge eating”;and‘diagnosis,signs and symptoms,comorbidities and prevalence and associated factors with BED’.CONCLUSION The number of publications has increased noticeably during the previous decade.There are indeed relatively few publications on BED from low-and middle-income nations,so much is to be learned from the experience of all countries.Studies on this topic are critical in all countries to discover risk factors and effective intervention measures.Although our findings are preliminary,they imply that the future prospects for interventions aimed at BED management are bright,focusing on complex models of care and long-term maintenance of therapeutic gains.展开更多
BACKGROUND Coronavirus disease 2019(COVID-19)is a global pandemic that can cause diarrhoea,nausea/vomiting,and abdominal pain,among other gastrointestinal(GI)symptoms.AIM To perform a bibliometric analysis of the glob...BACKGROUND Coronavirus disease 2019(COVID-19)is a global pandemic that can cause diarrhoea,nausea/vomiting,and abdominal pain,among other gastrointestinal(GI)symptoms.AIM To perform a bibliometric analysis of the global research production pertaining to GI involvement in COVID-19.METHODS The Scopus database was used to search the global literature on GI involvement in COVID-19 during 2020.A bibliometric review of these publications was also performed using VOSviewer.RESULTS Scopus had published 95615 documents on COVID-19 in all areas of research at the time of data collection.In total,1267 publications on the topic of GI and COVID-19 were identified.Research articles(n=606;47.83%),letters(293;23.13%),and reviews(186;14.68%)were the most popular types of documents.The most productive countries and institutions in this field were the United States and Huazhong University of Science and Technology.The most cited paper was Xiao et al,which was published in Gastroenterology as a brief communication,with 798 citations.This paper provides evidence for GI infection of COVID-19 and its possible faecal–oral transmission route.In the term cluster analysis,there were two frontiers in this field:GI manifestations among COVID-19 patients and the implications of COVID-19 for the gastroenterologist.CONCLUSION GI manifestations among COVID-19 patients and implications of COVID-19 for gastroenterologists were of interest,especially in the early stages of the pandemic.展开更多
文摘BACKGROUND Several bibliometric analyses have been carried out to identify research hotspots and trends in nonalcoholic fatty liver disease(NAFLD)research.Nonetheless,there are still significant knowledge gaps that must be filled to advance our understanding of and ability to treat NAFLD.AIM To evaluate,through bibliometric and visual analysis,the current status of related research,related research frontiers,and the developmental trends in the field of diet and NAFLD.METHODS We retrieved publications about diet and NAFLD published between 1987 and 2022 from Scopus.Next,we used VOSviewer 1.6.20 to perform bibliometric analysis and visualization.RESULTS We found a total of 1905 studies,including 1637(85.93%)original articles and 195(10.24%)reviews,focused on the examination of NAFLD and its correlation with diet that were published between 1987 and 2022.Among the remaining five types of documents,38 were letters,notes,editorials,meeting minutes,or brief surveys,representing 1.99%of the total documents.The countries with the most publications on this topic were China(n=539;28.29%),followed by the United States(n=379;19.90%),Japan(n=133;6.98%),and South Korea(n=127;6.6%).According to the citation analysis,the retrieved papers were cited an average of 32.3 times and had an h-index of 106,with 61014 total citations.The two main clusters on the map included those related to:(1)Inflammation and oxidative stress;and(2)Dietary interventions for NAFLD.CONCLUSION This was the first study to use data taken from Scopus to visualize network mapping in a novel bibliometric analysis of studies focused on diet and NAFLD.After 2017,the two domains that received the most attention were“dietary interventions for NAFL”’and“‘inflammation and oxidative stress implicated in NAFLD and its correlation with diet.”We believe that this study provides important information for academics,dietitians,and doctors,and that additional research on dietary interventions and NAFLD is warranted.
文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and NAFLD.AIM To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and IR.METHODS This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to 2022.The search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and NAFLD.VOSviewer software was used to visualize research trends,collaborations,and key thematic areas.The analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited references.RESULTS This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and 2022.The search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)reviews.The most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflammatory and high-fat diet impacts on NAFLD”.CONCLUSION This is the first bibliometric analysis to examine the relationship between IR and NAFLD.In response to the escalating global health challenge of NAFLD,this research highlights an urgent need for a better understanding of this condition and for the development of intervention strategies.Policymakers need to prioritize and address the increasing prevalence of NAFLD.
文摘BACKGROUND The global spread of severe acute respiratory syndrome coronavirus 2,responsible for coronavirus disease 2019(COVID-19),poses a significant risk to public health.Beyond the respiratory issues initially associated with the condition,severe cases of COVID-19 can also lead to complications in other organs,including the liver.Patients with severe COVID-19 may exhibit various clinical signs of liver dysfunction,ranging from minor elevations in liver enzymes without symptoms to more serious cases of impaired liver function.Liver damage is more commonly observed in patients with severe or critical forms of the disease.AIM To present the research landscape on COVID-19 and liver dysfunction while also offering valuable insights into the prominent areas of interest within this particular domain.METHODS On 18 February 2023,Scopus was utilised to conduct a comprehensive exploration of the relationship between COVID-19 and the liver dysfunction.The investigation encompassed the period from 1 January 2020 to 31 December 2022.Primary sources were meticulously examined and organised in a Microsoft Excel 2013 spreadsheet,categorised by journal,institution,funding agency,country and citation type.VOSviewer version 1.6.18 was employed to explore the prominent topics and knowledge network related to the subject.RESULTS There were 2336 publications on COVID-19 and liver dysfunction analysed in this study,of which 558 were published in 2020,891 in 2021 and 887 in 2022.Researchers from 111 different countries participated in the retrieved documents.The United States contributed the most studies,with 497 documents,representing 21.28%of the total,followed by China with 393 documents(16.82%)and Italy with 255 documents(10.92%).In the context of research related to COVID-19 and the liver,co-occurrence analysis identified three distinct clusters of topics:(1)‘COVID-19 vaccines in liver transplant recipients’;(2)‘liver function tests as a predictor of the severity and clinical outcomes in hospitalised patients’;and(3)‘care of patients with liver disease during the COVID-19 pandemic’.CONCLUSION This bibliometric study provides a comprehensive overview of liver-related publications in COVID-19 research over the past 3 years.This study highlights the significant contributions of high-income nations,particularly the United States,China,and Italy,to the production of liver-related scholarly literature in this field.Most of the articles focused on liver dysfunction in patients with COVID-19 and the implications of the virus for gastroenterologists and hepatologists.
文摘BACKGROUND Crohn’s disease represents a challenge for patients concerned with the modified diet regimen as well as practitioners who seek the best nutritional therapy.Crohn’s disease can alter the body’s ability to digest food and to absorb nutrients,resulting in severe vitamin deficiencies,malnutrition and sometimes lifethreatening complications.However,a comprehensive bibliometric analysis is lacking to map the current links between nutrition and Crohn’s disease in terms of the number of citations,geographic distribution and growth trends of publications.AIM To introduce the current state of research as well as hotspots in the field of nutrition and Crohn’s disease from a bibliometric standpoint.METHODS We searched the Scopus database and selected the relevant literature on nutrition and Crohn’s disease that met the inclusion criteria.We analyzed the publication trends and research hotspots by using video object segmentation viewer software.RESULTS We included 1237 publications.The number of documents published each year has increased steadily.The United States and the University of Otago,Christchurch,have had the highest productivity,with 208(16.81%)and 29(2.34%)documents,respectively.The“role of exclusive enteral nutrition for complicated Crohn’s disease”and“manipulation of the gut microbiota as a key target for Crohn’s disease”were the major research areas in 2016-2021,and they could be extensively investigated in the future.Meanwhile,research on“malnutrition in patients with Crohn’s disease”appeared to be an area that attracted more research attention before 2016.CONCLUSION This is the first bibliometric analysis to map the knowledge structure and trends regarding nutrition in Crohn’s disease research over the past two decades.The results provide a comprehensive summary and identification of the frontiers of nutrition and Crohn’s disease-related research,which may be used as a resource by researchers in the field.
文摘BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the microbiome plays a key role in the development and normal functioning of the gut–brain axis.AIM To facilitate the identification of specific areas of focus that may be of relevance to future research. This study represents a bibliometric analysis of the literature pertaining to the microbiome in IBS to understand the development of this field.METHODS The data used in our bibliometric analysis were retrieved from the Scopus database. The terms related to IBS and microbiome were searched in titles or abstracts within the period of 2000–2019. VOSviewer software was used for data visualization.RESULTS A total of 13055 documents related to IBS were retrieved at the global level. There were 1872 scientific publications focused on the microbiome in IBS. There was a strong positive correlation between publication productivity related to IBS in all fields and productivity related to the microbiome in IBS(r = 0.951, P < 0.001). The United States was the most prolific country with 449(24%) publications, followed by the United Kingdom(n = 176, 9.4%), China(n = 154, 8.2%), and Italy(n = 151, 8.1%). The h-index for all retrieved publications related to the microbiome in IBS was 138. The hot topics were stratified into four clusters:(1) The gut–brain axis related to IBS;(2) Clinical trials related to IBS and the microbiome;(3) Drugmediated manipulation of the gut microbiome;and(4) The role of the altered composition of intestinal microbiota in IBS prevention.CONCLUSION This is the first study to evaluate and quantify global research productivity pertaining to the microbiome in IBS. The number of publications regarding the gut microbiota in IBS has continuously grown since 2013. This finding suggests that the future outlook for interventions targeting the gut microbiota in IBS remains promising.
文摘BACKGROUND Clostridioides(Clostridium)difficile(C.difficile)is still the most common cause of healthcare-associated diarrhoea and is increasing in prevalence as a communityacquired infection.In addition,the emergence of antibiotic resistance in C.difficile can increase the likelihood of the disease developing and/or spreading.AIM To provide an up-to-date picture of the trends in publications related to C.difficile infection,together with specific insights into hot-button issues in this field.METHODS Publications on C.difficile infections in the field of microbiology between 2001 and 2020 were identified from the Scopus database and Reference Citation Analysis.Bibliometric indicators were determined,including the number and type of publications,countries,affiliations,funding agencies,journals and citation patterns.VOSviewer was used to determine research areas and hot-button issues by identifying recurring terms with a high relative occurrence in the title and abstract.RESULTS A total of 8127 documents on‘C.difficile-associated diarrhoea’published between 2001 and 2020 were retrieved from the Scopus database.In the last decade,there has been a significant almost fourfold increase in the number of published papers on this topic.The United States was among the countries(44.11%)with the most publications,and the most involved institution was the University of Leeds in the United Kingdom(2.50%).Three clusters of research were identified and included‘illness spectrum and severity,as well as the signs,symptoms and clinical pathogenesis of C.difficile’;‘laboratory diagnosis and characterization of C.difficile’and‘risk factors for C.difficile infection’.CONCLUSION This study contains the most up-to-date and comprehensive data ever compiled in this field.More international research and cross-institutional collaborations are needed to address more global C.difficile concerns and to benefit from greater sharing of expertise,which will result in higher quality or more effective studies in the future.Promising research avenues in the near future may draw the attention of relevant scientists and funding organizations and open up novel C.difficile infection–based diagnosis and treatment approaches.
文摘BACKGROUND One of the most popular bariatric procedures is sleeve gastrectomy,and it has become significantly more common in recent years.AIM To evaluate the research activity in sleeve gastrectomy over the last two decades,and to visualize the hot spots and emerging trends in this type of bariatric surgeryusing bibliometric methods.METHODS The Scopus database was used to search for publications related to sleeve gastrectomy.The retrieved publications were reviewed in terms of year of publication,type of study,country of origin,institutions,journals,and citation patterns by using descriptive analysis.Collaboration network and term cooccurrence analysis were visualized by using VOSviewer software.RESULTS The search strategy yielded a total of 6508 publications on sleeve gastrectomy from 2001 to 2020.As regards the document type,the majority were articles(n=5230;80.36%),followed by reviews(n=544;8.36%).The top three countries are the United States,with 1983 publications(30.47%),followed by France(600;9.22%)and Italy(417;6.71%).The most cited publication was published in 2012 by Schauer et al in the New England Journal of Medicine(n=1435 citations).This publication found that weight loss was greater in the sleeve gastrectomy group than in the medical therapy group.Furthermore,this study demonstrated that 12 mo of medical therapy plus bariatric surgery greatly improved glycemic regulation in obese patients with uncontrolled type 2 diabetes compared with medical therapy alone.The focus of the current literature on sleeve gastrectomy was directed toward several themes such as morbidity and potential complications,the complexity of the procedure and different surgical approaches,and diabetes and body mass index in correlation to sleeve gastrectomy.CONCLUSION The number of sleeve gastrectomy publications has gradually grown over the last 20 years.This bibliometric analysis could help researchers better understand the knowledge base and research frontiers surrounding sleeve gastrectomy.In addition,future studies may focus on emerging research hotspots.
文摘BACKGROUND Nutrition is a significant modifiable element that influences the composition of the gastrointestinal microbiota,implying the possibility of therapeutic diet methods that manipulate the composition and diversity of the microbial.AIM To overview research papers on nutrition and gut microbiota and determines the hotspots in this field at the global level.METHODS Scopus and Reference Citation Analysis were used to construct a bibliometric technique.It was decided to create bibliometric indicators and mapping as in most previous studies.2012 through 2021 served as the study's timeframe.RESULTS A total of 5378 documents from the Scopus database were selected for analysis.Of all retrieved studies,78.52%were research papers(n=4223),followed by reviews(n=820;15.25%).China ranked first with a total number of articles of 1634(30.38%),followed by the United States in second place with a total number of articles of 1307(24.3%).In the last decade,emerging hotspots for gut microbiota and nutrition research included"gut microbiota metabolism and interaction with dietary components","connection between the gut microbiota and weight gain",and"the influence of high-fat diet and gut microbiota on metabolic disorders".CONCLUSION This is the first thorough bibliometric analysis of nutrition and gut microbiota publications conducted on a global level.Investigation of the association between nutrition/diet and the gut microbiota is still in its infancy and will be expanded in the future.However,according to recent trends,the"effect of gut microbiota and high-fat diet on metabolic disorders"will be an increasing concern in the future.
文摘BACKGROUND Recently,neonatal abstinence syndrome(NAS)emerged as a significant global concern with a dramatic increase in healthcare expenditures.The incidence of the NAS has increased notably in the past decade and emergence as a global public health problem.AIM To evaluate the development and trend of global NAS research from 1958 to 2019 by bibliometric analysis.METHODS Analyzed aspects included publication output per year,language,document types,journals,countries/territories,h-index,authors,and top research priorities.The VOSviewer was used to determine the top research priorities,and trends,and to present bibliometric networks concerning various dimensions,such as coauthorship,authors,and countries.RESULTS A total of 1738 articles were retrieved in the Scopus database from 1958 to 2019.It was found that the great majority of the total NAS documents(n=1295)were original articles followed by reviews(n=268)and letters(n=48).The most productive countries in the NAS field were the United States(n=833),Canada(n=112),the United Kingdom(n=111),and Germany(n=77).Treatment and hospital outcomes in NAS,evidence-based nurse-driven interventions for the care of newborns with NAS,and a systematic reviews and network meta-analysis for therapeutic approaches of NAS were found in recent years(after 2010),compared with terms such as pathophysiology,mechanisms of NAS,and signs and symptoms in the early years.CONCLUSION Treatment and pediatric outcomes and the effectiveness of pharmacological treatment may be frontiers in the NAS field,and continued efforts from researchers are needed in those topics.
文摘BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global health.In individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and increased mortality.AIM To identify research hotspots and prospects,we used bibliometrics to examine the global production of COVID-19 literature published in the field of oncology.METHODS Data on publication output were identified based on the Scopus database between January 1,2020,and June 21,2022.This study used VOSviewer to analyze collaboration networks among countries and assess the terms most often used in the titles and abstracts of retrieved publications to determine research hotspots linked to cancer and COVID-19.The Impact Index Per Article for the top 10 high-cited papers collected from Reference Citation Analysis(RCA)are presented.RESULTS A total of 7015 publications were retrieved from the database.The United States published the greatest number of articles(2025;28.87%),followed by Italy(964;13.74%),the United Kingdom(839;11.96%),and China(538;7.67%).The University of Texas MD Anderson Cancer Center(n=205,2.92%)ranked first,followed by the Memorial Sloan-Kettering Cancer Center(n=176,2.51%).The European Journal of Cancer(n=106,1.51%)ranked first,followed by the Frontiers in Oncology(n=104,1.48%),Cancers(n=102,1.45%),and Pediatric Blood and Cancer(n=95;1.35%).The hot topics were stratified into“cancer care management during the COVID-19 pandemic”;and“COVID-19 vaccines in cancer patients”.CONCLUSION This is the first bibliometric analysis to determine the present state and upcoming hot themes related to cancer and COVID-19 and vice versa using VOSviewer during the early stages of the pandemic.The emergence of hot themes related to cancer and COVID-19 may aid researchers in identifying new research areas in this field.
文摘BACKGROUND Binge-eating disorder(BED)is a clinical syndrome and is considered the most common type of eating disorder.However,our understanding of the global performance and progress of BED research is limited.AIM To describe and perform a bibliometric analysis of the state of BED research.METHODS The term‘Binge eating’was searched in the title throughout the previous year’s up to December 31,2020.We searched the Scopus and Reference Citation Analysis for publications on Binge eating.The VOSviewer software version 1.6.17 was used to produce the network visualization map of the most frequent author,collaborative relationships between countries/regions,and to determine the hotspots related to binge eating research.In addition,conventional bibliometric indicators were generated.RESULTS The search strategy found 2713 total articles and an average of 62 articles per year.Among them,‘Article’represented 82.49%of the publications(n=2238 articles)and was the most frequent type,followed by reviews(n=243;8.96%).The number of publications increased steadily during the last decade of the study period.One hundred and thirty-two countries contributed to binge eating research,with 1495(55.11%)articles published in the United States,followed by Italy with 256(9.44%),the United Kingdom with 183(6.75%),and Germany with 182(6.71%).Currently,the main hot topics related to BED are‘type of treatment and management and treatment provided to BED”;“processes and pathways to binge eating”;and‘diagnosis,signs and symptoms,comorbidities and prevalence and associated factors with BED’.CONCLUSION The number of publications has increased noticeably during the previous decade.There are indeed relatively few publications on BED from low-and middle-income nations,so much is to be learned from the experience of all countries.Studies on this topic are critical in all countries to discover risk factors and effective intervention measures.Although our findings are preliminary,they imply that the future prospects for interventions aimed at BED management are bright,focusing on complex models of care and long-term maintenance of therapeutic gains.
文摘BACKGROUND Coronavirus disease 2019(COVID-19)is a global pandemic that can cause diarrhoea,nausea/vomiting,and abdominal pain,among other gastrointestinal(GI)symptoms.AIM To perform a bibliometric analysis of the global research production pertaining to GI involvement in COVID-19.METHODS The Scopus database was used to search the global literature on GI involvement in COVID-19 during 2020.A bibliometric review of these publications was also performed using VOSviewer.RESULTS Scopus had published 95615 documents on COVID-19 in all areas of research at the time of data collection.In total,1267 publications on the topic of GI and COVID-19 were identified.Research articles(n=606;47.83%),letters(293;23.13%),and reviews(186;14.68%)were the most popular types of documents.The most productive countries and institutions in this field were the United States and Huazhong University of Science and Technology.The most cited paper was Xiao et al,which was published in Gastroenterology as a brief communication,with 798 citations.This paper provides evidence for GI infection of COVID-19 and its possible faecal–oral transmission route.In the term cluster analysis,there were two frontiers in this field:GI manifestations among COVID-19 patients and the implications of COVID-19 for the gastroenterologist.CONCLUSION GI manifestations among COVID-19 patients and implications of COVID-19 for gastroenterologists were of interest,especially in the early stages of the pandemic.
