Clinical Application of Double Ovulation Stimulation in Patients with Diminished Ovarian Reserve and Asynchronous Follicular Development Undergoing Assisted Reproduction Technology

Objective This study aimed to compare the clinical effects of double ovulation stimulation(DouStim)applied during the follicular and luteal phases with the antagonist protocol in patients with diminished ovarian reserve(DOR)and asynchronous follicular development undergoing assisted reproductive technology(ART).Methods The clinical data of patients with DOR and asynchronous follicular development receiving ART from January 2020 to December 2021 were retrospectively analyzed.The patients were divided into two groups according to their ovulation stimulation protocol:DouStim group(n=30)and antagonist group(n=62).Assisted reproduction and clinical pregnancy outcomes were compared between the two groups.Results In the DouStim group,the number of oocytes retrieved,metaphase II(MII)oocytes,two-pronuclei(2PN),day 3(D3)embryos,D3 high-quality embryos as well as blastocyst formation,implantation,and human chorionic gonadotropin-positive rates were significantly greater than those in the antagonist group(all P<0.05).No significant differences were found in MII,fertilization,or continued pregnancy rates at the first frozen embryo transfer(FET),in-vitro fertilization(IVF)cancellation,or early medical abortion rates between the groups(all P>0.05).Except for the early medical abortion rate,the DouStim group generally had favorable outcomes.In the DouStim group,the dosage and duration of gonadotropin and the fertilization rate were significantly greater in the first ovulation stimulation induction than in the second ovulation stimulation induction(P<0.05).Conclusion The DouStim protocol efficiently and economically obtained more mature oocytes and high-quality embryos for patients with DOR and asynchronous follicular development.

深海采矿柔性管力学性能及加工工艺研究综述

海洋蕴藏着储量丰富的矿产资源,深海矿产资源开发逐渐成为学术界和工程界的研究热点。管道提升式开采方案是目前公认的最具商业前景的海洋矿产开发方案。矿产输运管道作为连接海底中继舱和海上采矿平台的纽带,需要承受恶劣的风、浪、流环境载荷和复杂作业工况的工作载荷,其设计制造和力学性能分析一直备受关注。相比于刚性管道,柔性管道的弯曲刚度小、便于安装与回收、使用寿命较长。然而,柔性管道的结构复杂,各层之间相互影响,金属柔性管道由于自身结构的限制,在深海采矿行业中难以广泛应用,人们开始把目光放在非金属柔性管的设计与应用上。本文回顾了柔性管的发展历程,总结阐述了柔性管设计及加工制造中的力学性能分析方法和力学特性,并对柔性管设计制造的未来发展提供力所能及的展望。

脉动风作用下塔线体系的风致响应特性分析

塔线体系是输电系统的基础,风载荷作为塔线体系所受的主要载荷,在风载荷下塔线体系的结构安全分析十分重要。考虑脉动风载荷的影响,采用Kaimal风谱与谐波叠加法,拟合确定了脉动风速,并考虑了风速沿高度的变化情况。基于ABAQUS有限元软件,建立“四塔五线”的典型耐张段模型,分析不同风速、风向角对于塔线体系结构动力响应的影响机制。通过对杆塔塔头位移、杆塔底座支反力以及塔线体系的应力集中部位的分析得出:随着风速的增大,重力塔与张力塔在两个方向的塔头位移幅值增大;随着风向角的增大,张力塔在两个方向的塔头位移幅值增大;重力塔在垂直于塔线体系方向的位移幅值增大,沿塔线体系方向的位移幅值先增大后减小,在45°时达到最大幅值。杆塔的应力集中点基本位于杆塔的钢材集中处。

不同风向下输电塔对气象监测的塔影干扰效应

针对均匀风荷载作用下5C3-SJ3型输电塔的绕流流场开展数值模拟,探究0°~180°风向角范围内,输电塔对气象监测的塔影干扰效应。通过求解雷诺平均Navier-Stokes方程模拟输电塔周围绕流流场,湍流模型采用Realizable k-ε模型,并且运用切割体网格技术对计算域进行网格划分。通过探究各截面风速变化较小的区域,讨论不同风向下塔影干扰效应最小的截面,揭示了风向角对输电塔塔影干扰效应的影响规律。结果表明:塔腿横隔面和塔身横隔面中迎风侧杆件附近的塔影干扰效应最小,可考虑将气象监测点设置在相应位置上。通过三维计算流体动力学的方法,确定了塔影干扰效应较小的区域,并分析了风向角对塔影干扰效应的影响程度。研究结果对风资源数据的准确评估具有一定的指导意义。