Hutter et al.1 first reported that a bone marrow transplant using stem cells derived from a donor with homozygous CCR5 delta32 gene mutation remained HIV-positive but virus-free(below the limits of detection)after hal...Hutter et al.1 first reported that a bone marrow transplant using stem cells derived from a donor with homozygous CCR5 delta32 gene mutation remained HIV-positive but virus-free(below the limits of detection)after halting antiretroviral therapy.Since this observation in 2009,mutation of the CCR5 gene has become an important target in the prevention and treatment of HIV infection.The CRISPR-Cas9 system,which has been called the biggest biotech discovery in the history of molecular biology,can be used for precise genome engineering with the aim of treating genetic disorders.Currently,the application of gene-editing tools,such as CRISPR-Cas9,for genetic engineering of embryos for use in assisted reproduction is prohibited in much of Europe,the United States,and China.2–3.展开更多
Singapore started to tackle the challenges of an aging society in the 1980s after its fertility declined to sub-replacement levels.A core component of the city-state’s aging policy is to foster intergenerational supp...Singapore started to tackle the challenges of an aging society in the 1980s after its fertility declined to sub-replacement levels.A core component of the city-state’s aging policy is to foster intergenerational support,which is based on the value of filial piety,harmonious intergenerational relations,and the elderly as a resource.This paper introduces the concept of state familism to capture Singapore’s comprehensive efforts to strengthen the role of the family in old-age support while promoting mutual assistance across generations.The relevant policies range from the Central Provident Fund,housing,taxation,to old-age support packages.These efforts distinguish Singapore from other Asian countries where the role of the family is sometimes stressed more in rhetoric than in action.State familism in Singapore has drawn criticisms as it is perceived as an attempt to reduce the government’s responsibility.In the recent decade,the Singapore state significantly increased direct financial support for the elderly while keeping the policy of fostering intergenerational support in place.The paper concludes by discussing the implications of Singapore’s state familism for China and other countries.展开更多
The article“State familism in action:aging policy and intergenerational support in Singapore”,written by Shaohua Zhan and Lingli Huang,was originally published electronically on the publisher’s internet portal on 3...The article“State familism in action:aging policy and intergenerational support in Singapore”,written by Shaohua Zhan and Lingli Huang,was originally published electronically on the publisher’s internet portal on 30th May,2023 without open access.展开更多
基金supported by the National Natural Science Foundation of China (81772369)supported by the CAMS Innovation Fund for Medical Sciences (CIFMS,2017-I2M-3-001)
文摘Hutter et al.1 first reported that a bone marrow transplant using stem cells derived from a donor with homozygous CCR5 delta32 gene mutation remained HIV-positive but virus-free(below the limits of detection)after halting antiretroviral therapy.Since this observation in 2009,mutation of the CCR5 gene has become an important target in the prevention and treatment of HIV infection.The CRISPR-Cas9 system,which has been called the biggest biotech discovery in the history of molecular biology,can be used for precise genome engineering with the aim of treating genetic disorders.Currently,the application of gene-editing tools,such as CRISPR-Cas9,for genetic engineering of embryos for use in assisted reproduction is prohibited in much of Europe,the United States,and China.2–3.
基金The research for this study is supported by a Singapore Ministry of Education Tier 1 grant(RG81/17).
文摘Singapore started to tackle the challenges of an aging society in the 1980s after its fertility declined to sub-replacement levels.A core component of the city-state’s aging policy is to foster intergenerational support,which is based on the value of filial piety,harmonious intergenerational relations,and the elderly as a resource.This paper introduces the concept of state familism to capture Singapore’s comprehensive efforts to strengthen the role of the family in old-age support while promoting mutual assistance across generations.The relevant policies range from the Central Provident Fund,housing,taxation,to old-age support packages.These efforts distinguish Singapore from other Asian countries where the role of the family is sometimes stressed more in rhetoric than in action.State familism in Singapore has drawn criticisms as it is perceived as an attempt to reduce the government’s responsibility.In the recent decade,the Singapore state significantly increased direct financial support for the elderly while keeping the policy of fostering intergenerational support in place.The paper concludes by discussing the implications of Singapore’s state familism for China and other countries.
文摘The article“State familism in action:aging policy and intergenerational support in Singapore”,written by Shaohua Zhan and Lingli Huang,was originally published electronically on the publisher’s internet portal on 30th May,2023 without open access.