锂离子电池高镍层状氧化物正极结构失效机制

高镍层状氧化物具有成本低、能量密度高的优点,被认为是新一代锂离子电池的理想正极材料。然而,由于在使用中其结构的耐久性与安全性问题,在实际应用过程中仍然面临着严峻的挑战。深入了解电极材料容量衰减过程中的结构演变对发展高性能层状氧化物电极材料具有重要的指导意义。本文综述了近年来高镍层状氧化物正极失效机理的研究进展,包括从高镍层状氧化物的内部结构演变、表面成分变化和热失控条件下的性质等方面,进行了详细的梳理。之后,本文介绍了国内外最新的高镍层状氧化物的改性策略,并对高镍氧化物正极结构研究的发展方向进行了总结和展望。

Key questions and outcomes for the clinical practice guideline on acupuncture and moxibustion for allergic rhinitis

Objective:Formulating critical clinical questions and outcomes is essential for developing clinical practice guidelines(CPGs).This study aims to formulate the key clinical questions and outcomes for the CPG on acupuncture and moxibustion for allergic rhinitis(AR).Methods:PICO(patient,intervention,comparator,and outcome)question survey,Delphi survey,and consensus conference of the guideline development group(GDG)were employed.PICO questionnaires were used to gather and analyze the target users’key demands and interests.The GDG then selected the critical clinical questions and outcomes via a mixed method of Delphi survey and consensus conference.Results:Fifteen potential clinical questions and ten types of outcomes were formulated based on the analysis of 123 responses from seventeen countries on five continents.After two rounds of the Delphi survey and complete discussions,a consensus was reached by the GDG that all potential questions were included.After three rounds of the Delphi survey and complete debate,the consensus was reached that nine outcomes were considered important.Conclusion:Fifteen key clinical questions and nine important outcomes were formulated for the CPG.These covered issues elicited the most attention from global users in acupuncture therapy and AR.The results will contribute to the CPGs development and future clinical studies.

Understanding of Guidance for Acupuncture and Moxibustion Interventions on COVID-19(Second edition) issued by CAAM

At present,the situation of global fight against COVID-19 is serious.WHO(World Health Organization)-China Joint Mission fully confirms the success of"China’s model"against COVID-19 in their report.In fact,one particular power in"China’s model"is acupuncture and moxibustion of traditional Chinese medicine.To better apply"non-pharmaceutic measures"-the external technique of traditional Chinese medicine,in the article,the main content of Guidance for acupuncture and moxibustion interventions on COVID-19(Second edition)issued by China Association of Acupuncture-Moxibution is introduced and the discussion is stressed on the selection of moxibustion device and the duration of its exertion.

Development trend and current situation of acupuncture-moxibustion indications

To discuss the dominant diseases of acupuncture and moxibustion and their trend in development.At present,the concepts of acupuncture and moxibustion disease spectrum include efficacy-based graded disease spectrum of acupuncture and moxibustion and evidence-based graded disease spectrum of acupuncture and moxibustion.Hence,the ranges of dominant diseases are various in terms of the different concepts.Regarding the efficacy-based graded disease spectrum,81 dominant diseases are included.In accordance with the principle of disease spectrum of evidence-based acupuncture and moxibustion,the articles of systematic reviews and meta-analysis of acupuncture and moxibustion published in Chinese medical journals were retrieved,and thus 68 dominant diseases of acupuncture and moxibustion were collected.In view of the retrieval result and the effect characteristics of acupuncture and moxibustion,the authors believe that the following 4 aspects should be involved in the development of the dominant diseases of acupuncture and moxibustion,named(1)painful diseases,(2)neurological disorders,(3)mental,cognitive and affective diseases and(4)immune-endocrine disorders.

China Association of Acupuncture–Moxibustion Evidence-based clinical practice guideline of acupuncture and moxibustion: Primary dysmenorrhea

Dysmenorrhea refers to periodic abdominal pain,or radiating to lumbosacral region.For the severe case,it is intolerable,combined with nausea and vomiting sometimes.This disease is commonly seen in unmarried young women.Epidemiological studies have shown that dysmenorrhea is the most common gynecological disease,especially in young women[1].Acupuncture and moxibustion have a long history in the treatm ent of primary dysmenorrhea(hereinafter referred to as PD),and compared with medication,the advantages are presented in the treatment.Entrusted by the Standardization Working Committee of China Association for Acupuncture and Moxibustion(CAAM),Department of Acupuncture and Moxibustion,Dongzhimen Hospital,Beijing University of Traditional Chinese Medicine has undertaken the drafting of Evidence-Based Clinical Practice Guideline of Acupuncture and Moxibustion:Primary Dysmenorrhea(hereinafter referred to as the Guideline).The Guideline was issued in 2014 by CAAM.It summarizes the research achievements in acupuncture-moxibustion treatm ent for dysmenorrhea in recent decades and is intended to standardize the clinical regimen of treatm ent with acupuncture and moxibustion so as to improve the clinical effect.

Filiform needle acupuncture for allergic rhinitis:A systematic review and meta-analysis

Background:Filiform needle acupuncture(FNA),the most classical and widely applied acupuncture method based on traditional Chinese medicine theory,has shown a promising effect in the treatment of allergic rhinitis(AR).Objective:To evaluate the efficacy,safety,cost-effectiveness,and patient preference of FNA in the treatment of AR by comparing FNA with sham acupuncture,no treatment,and conventional medication.Search strategy:Eight electronic databases were systematically searched from inception to October 14,2021.Additional studies were acquired from clinical trial registration platforms and reference lists.Inclusion criteria:Randomized controlled trials were included if they compared FNA with either sham acupuncture,no treatment or conventional medication for AR.Data extraction and analysis:Two researchers extracted data independently of each other using a predesigned data acquisition form,and results were cross-checked after completion.The primary outcome was symptom score(Total Nasal Symptom Score or Visual Analogue Scale),and the secondary outcomes were the AR control questionnaire,quality of life(QoL)score(Different versions of Rhinoconjunctivitis Quality of Life Questionnaire),medication score(use of rescue medication),mental health score,total IgE,adverse event rate,clinical economic indicators,and patient satisfaction score.Standardized mean difference(SMD)or mean difference(MD)with 95% confidence interval was used to calculate the effect size for continuous data,while risk ratio with 95%CI was used for dichotomous data.Results:Thirty studies were included in this review.Compared with sham acupuncture,FNA significantly reduced the symptom score(SMD:-0.29[-0.43,-0.15]),AR’s impact on QoL(SMD:-0.23[-0.37,-0.08])and medication score(SMD:-0.3[-0.49,-0.11]).Compared with no treatment,FNA dramatically reduced the symptom score(SMD:-0.8[-1.2,-0.39])and AR’s impact on QoL(SMD:-0.82[-1.13,-0.52]).There were no increased rates of adverse events with FNA compared to sham acupuncture and no treatment.FNA increased patient satisfaction and may be cost-effective.Most pieces of evidence from the above two comparisons were of high confidence.Moreover,FNA significantly outperformed conventional medication in reducing the symptom score(SMD:-0.48[-0.85,-0.1])and displayed a lower rate of adverse events,but the quality of evidence was very low.Conclusion:FNA is an effective and safe intervention for AR and can help with symptom relief,QoL improvement,reducing medication usage,and increasing patient satisfaction.Further studies are needed to verify its cost-effectiveness and superiority over conventional medication and the best therapeutic strategies.

THE POSITIVE EFFECTS OF VOLATILE COMPONENTS IN JIAWEI WENDAN PRESCRIPTION ON THE IMPROVEMENT OF THE AUTISTIC BEHAVIOR IN RATS

The objective was to investigate the effects of volatile components in Jiawei Wendan prescription on autistic behavior in rats,to analyze the volatile constituents and then to explore its effective components based on the treatment of autism.The pregnant mice were divided into two groups according to the method that Schneider used.