This study quantified the regional damages resulting from temperature and sea level changes using the Regional Integrated of Climate and Economy(RICE)model,as well as the effects of enabling and disabling the climate ...This study quantified the regional damages resulting from temperature and sea level changes using the Regional Integrated of Climate and Economy(RICE)model,as well as the effects of enabling and disabling the climate impact module on future emission pathways.Results highlight varied damages depending on regional economic development and locations.Specifically,China and Africa could suffer the most serious comprehensive damages caused by temperature change and sea level rise,followed by India,other developing Asian countries(OthAsia),and other high-income countries(OHI).The comprehensive damage fractions for China and Africa are projected to be 15.1%and 12.5%of gross domestic product(GDP)in 2195,with corresponding cumulative damages of 124.0 trillion and 87.3 trillion United States dollars(USD)from 2005 to 2195,respectively.Meanwhile,the comprehensive damage fractions in Japan,Eurasia,and Russia are smaller and projected to be lower than 5.6%of GDP in 2195,with cumulative damages of 6.8 trillion,4.2 trillion,and 3.3 trillion USD,respectively.Additionally,coastal regions like Africa,the European Union(EU),and OHI show comparable damages for sea level rise and temperature change.In China,however,sea level-induced damages are projected to exceed those from temperature changes.Moreover,this study indicates that switching the damage modules on or off affects the regional and global emission trajectories,but the magnitude is relatively small.By 2195,global emissions under the experiments with all of the damage modules switched off,only the sea level damage module switched on,and only the temperature damage module switched on,were 3.5%,2.3%and 1.2%higher than those with all of the damage modules switched on,respectively.展开更多
[Objectives]This study was conducted to investigate the species and occurrence patterns of main pests in the Chinese chive(Allium tuberosum)fields in Shijiazhuang.[Methods]Our research group conducted a systematic inv...[Objectives]This study was conducted to investigate the species and occurrence patterns of main pests in the Chinese chive(Allium tuberosum)fields in Shijiazhuang.[Methods]Our research group conducted a systematic investigation on the types and occurrence of major pests in Chinese chive fields in Shijiazhuang from April 2019 to November 2020 using the Malaise net method.[Results]The main pests harming Chinese chives in the region included Thrips tabaci,Bradysia odoriphaga,Luperomorpha suturalis,Acrolepla alliella,Liriomyza chinensis,and Neotoxoptera formosana.The pest populations in the region mainly experienced two peak periods,from mid June to mid July and from late August to late September.Meanwhile,corresponding green prevention and control measures were proposed based on the occurrence characteristics and biological characteristics of different pests in local chive fields.[Conclusions]Predicting the occurrence of pests in Chinese chive fields can provide basis for farmers to take timely prevention and control measures,reduce the damage of pests in the field to Chinese chives and realize high-quality production of Chinese chive.展开更多
Epilepsy is considered as a common and diverse set of chronic neurological disorders and its symptoms can be controlled by antiepileptic drugs(AEDs). The presence of p-glycoprotein and multi-drug resistance transporte...Epilepsy is considered as a common and diverse set of chronic neurological disorders and its symptoms can be controlled by antiepileptic drugs(AEDs). The presence of p-glycoprotein and multi-drug resistance transporters in the blood-brain barrier could prevent the entry of AEDs into the brain, causing drug resistant epilepsy. To overcome this problem, we propose using carboxymethyl chitosan nanoparticles as a carrier to deliver carbamazepine(CBZ) intranasally with the purpose to bypass the blood-brain barrier thus to enhance the brain drug concentration and the treatment efficacy. Results so far indicate that the developed CBZNPs have small particle size(218.76 ± 2.41 nm) with high drug loading(around 35%) and high entrapment efficiency(around 80%). The in vitro release profiles of CBZ from the NPs are in accordance with the Korsmeyer-peppas model. The in vivo results show that both encapsulation of CBZ in nanoparticles and the nasal route determined the enhancement of the drug bioavailability and brain targeting characteristics.展开更多
Future climate change is usually projected by coupled earth system models under specific emission sce- narios designed by integrated assessment models (IAMs), and this offline approach means there is no interaction ...Future climate change is usually projected by coupled earth system models under specific emission sce- narios designed by integrated assessment models (IAMs), and this offline approach means there is no interaction between the coupled earth system models and the IAMs. This paper introduces a new method to design possible future emission scenarios and corresponding climate change, in which a simple economic and climate damage component is added to the coupled earth system model of Beijing Normal University (BNU-ESM). With the growth of population and technological expertise and the declining emission-to-output ratio described in the Dynamic Inte- grated Climate-Economy model, the projected carbon emission is 13.7 Gt C, resulting in a 2.4℃ warming by the end of the twenty-first century (2080-2099) compared with 1980-1999. This paper also suggests the importance of the land and ocean carbon cycle in determining the CO2 con- centration in the atmosphere. It is hoped that in the near future the next generation of coupled earth system models that include both the natural system and the social dimension will be developed.展开更多
The areas covered by 1.5 ℃ and 2.0 ℃ warming thresholds under RCP2.6, RCP4.5, and RCP8.5 were analyzed based on 22 CMIP5 models. More than 90% of the model runs are in agreement that by the end of the 21 st century,...The areas covered by 1.5 ℃ and 2.0 ℃ warming thresholds under RCP2.6, RCP4.5, and RCP8.5 were analyzed based on 22 CMIP5 models. More than 90% of the model runs are in agreement that by the end of the 21 st century, near-surface air temperature changes over ~5%(~2%), ~40%(~18%), and ~92%(~86%)of the globe will cross the 1.5 ℃(2.0 ℃) threshold under RCP2.6, RCP4.5, and RCP8.5, respectively. Under RCP8.5, nearly the whole of North America, Europe + Russia, Africa, and Asia–Russia will cross the 1.5 ℃(2.0 ℃) threshold in ~2050(~2060), while the coverage rates over South America and Oceania are ~80%(~75%) and ~50%(~30%), respectively. The threshold-onset time(TOT) for 2 ℃ warming is earliest over Europe + Russia and North America, followed by Africa, Asia–Russia, South America, and finally Oceania under the RCP4.5 and RCP8.5 scenarios. The TOT for 1.5 ℃ is ~10–30 years ahead of that for 2.0 ℃.展开更多
Beak and feather disease virus(BFDV) is an infectious agent responsible for feather degeneration and beak deformation in birds. In March 2017, an epidemic of psittacine beak and feather disease(PBFD) struck a farm in ...Beak and feather disease virus(BFDV) is an infectious agent responsible for feather degeneration and beak deformation in birds. In March 2017, an epidemic of psittacine beak and feather disease(PBFD) struck a farm in Fuzhou in the Fujian Province of southeast China, resulting in the death of 51 parrots. In this study, the disease was diagnosed and the pathogen was identified by PCR and whole genome sequencing. A distinct BFDV strain was identified and named as the FZ strain.This BFDV strain caused severe disease symptoms and pathological changes characteristic of typical PBFD in parrots, for example, loss of feathers and deformities of the beak and claws, and severe pathological changes in multiple organs of the infected birds. Phylogenetic analysis showed that the FZ strain was more closely related to the strain circulating in New Caledonia than the strains previously reported in China. Nucleotide homology between the FZ strain and other 43 strains of BFDV ranged from 80.0% to 92.0%. Blind passage experiment showed that this strain had limited replication capability in SPF Chicken Embryos and DF-1 Cells. Furthermore, the capsid(Cap) gene of this FZ strain was cloned into the p GEX-4 T-1 expression vector to prepare the polyclonal anti-Cap antibody. Western blotting analysis using the anti-Cap antibody further confirmed that the diseased parrots were infected with BFDV. In this study, a PBFD and its pathogen was identified for the first time in Fujian Province of China, suggesting that future surveillance of BFDV should be performed.展开更多
This paper proposes a secure,reliable and collaborative data-sharing system for China’s housing provident fund based on blockchain.Firstly,federal computingwas introduced to realize“available but invisible”sharing ...This paper proposes a secure,reliable and collaborative data-sharing system for China’s housing provident fund based on blockchain.Firstly,federal computingwas introduced to realize“available but invisible”sharing of data about housing provident fund,which reduces the data leakage risk and improves the data availability.Secondly,four data sharing modes were proposed to deal with different situations with different amount of data provider and data.Lastly,to realize individual data deep sharing on the premise of security,an enterprise and personal information query authorization mechanism was established to provide solutions to personal and institutional authorization.This system helps to realize both the internal and external data sharing of the housing provident fund system under the premise of security and privacy protection.This system improves the efficiency of housing provident fund issue,and fully taps the value of data comprehensively.展开更多
基金funded by the National Natu-ral Science Foundation of China(Grant No.42075044 and No.41975112)a project supported by the Innovation Group Project of the Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)(Grant No.311022006).
文摘This study quantified the regional damages resulting from temperature and sea level changes using the Regional Integrated of Climate and Economy(RICE)model,as well as the effects of enabling and disabling the climate impact module on future emission pathways.Results highlight varied damages depending on regional economic development and locations.Specifically,China and Africa could suffer the most serious comprehensive damages caused by temperature change and sea level rise,followed by India,other developing Asian countries(OthAsia),and other high-income countries(OHI).The comprehensive damage fractions for China and Africa are projected to be 15.1%and 12.5%of gross domestic product(GDP)in 2195,with corresponding cumulative damages of 124.0 trillion and 87.3 trillion United States dollars(USD)from 2005 to 2195,respectively.Meanwhile,the comprehensive damage fractions in Japan,Eurasia,and Russia are smaller and projected to be lower than 5.6%of GDP in 2195,with cumulative damages of 6.8 trillion,4.2 trillion,and 3.3 trillion USD,respectively.Additionally,coastal regions like Africa,the European Union(EU),and OHI show comparable damages for sea level rise and temperature change.In China,however,sea level-induced damages are projected to exceed those from temperature changes.Moreover,this study indicates that switching the damage modules on or off affects the regional and global emission trajectories,but the magnitude is relatively small.By 2195,global emissions under the experiments with all of the damage modules switched off,only the sea level damage module switched on,and only the temperature damage module switched on,were 3.5%,2.3%and 1.2%higher than those with all of the damage modules switched on,respectively.
基金Supported by Observation and Monitoring Project of National Data Center for Insect Natural Enemies(ZX09S030101)Technology Demonstration and Service Special Project of Hebei Academy of Agriculture and Forestry Sciences(13000024P0012F410114C).
文摘[Objectives]This study was conducted to investigate the species and occurrence patterns of main pests in the Chinese chive(Allium tuberosum)fields in Shijiazhuang.[Methods]Our research group conducted a systematic investigation on the types and occurrence of major pests in Chinese chive fields in Shijiazhuang from April 2019 to November 2020 using the Malaise net method.[Results]The main pests harming Chinese chives in the region included Thrips tabaci,Bradysia odoriphaga,Luperomorpha suturalis,Acrolepla alliella,Liriomyza chinensis,and Neotoxoptera formosana.The pest populations in the region mainly experienced two peak periods,from mid June to mid July and from late August to late September.Meanwhile,corresponding green prevention and control measures were proposed based on the occurrence characteristics and biological characteristics of different pests in local chive fields.[Conclusions]Predicting the occurrence of pests in Chinese chive fields can provide basis for farmers to take timely prevention and control measures,reduce the damage of pests in the field to Chinese chives and realize high-quality production of Chinese chive.
基金the Academic Research Fund,Faculty of Science,National University of Singapore,R148-000-180-112
文摘Epilepsy is considered as a common and diverse set of chronic neurological disorders and its symptoms can be controlled by antiepileptic drugs(AEDs). The presence of p-glycoprotein and multi-drug resistance transporters in the blood-brain barrier could prevent the entry of AEDs into the brain, causing drug resistant epilepsy. To overcome this problem, we propose using carboxymethyl chitosan nanoparticles as a carrier to deliver carbamazepine(CBZ) intranasally with the purpose to bypass the blood-brain barrier thus to enhance the brain drug concentration and the treatment efficacy. Results so far indicate that the developed CBZNPs have small particle size(218.76 ± 2.41 nm) with high drug loading(around 35%) and high entrapment efficiency(around 80%). The in vitro release profiles of CBZ from the NPs are in accordance with the Korsmeyer-peppas model. The in vivo results show that both encapsulation of CBZ in nanoparticles and the nasal route determined the enhancement of the drug bioavailability and brain targeting characteristics.
基金supported by the National Natural Science Foundation of China (41605036 and 41305053)the National Key Research and Development Program of China (2016YFA0602703)+1 种基金the National-Level Major Cultivation Project of Guangdong Province (2014GKXM058)the Open Project of the State Key Laboratory of Cryospheric Science (SKLCS-OP-2016-09)
文摘Future climate change is usually projected by coupled earth system models under specific emission sce- narios designed by integrated assessment models (IAMs), and this offline approach means there is no interaction between the coupled earth system models and the IAMs. This paper introduces a new method to design possible future emission scenarios and corresponding climate change, in which a simple economic and climate damage component is added to the coupled earth system model of Beijing Normal University (BNU-ESM). With the growth of population and technological expertise and the declining emission-to-output ratio described in the Dynamic Inte- grated Climate-Economy model, the projected carbon emission is 13.7 Gt C, resulting in a 2.4℃ warming by the end of the twenty-first century (2080-2099) compared with 1980-1999. This paper also suggests the importance of the land and ocean carbon cycle in determining the CO2 con- centration in the atmosphere. It is hoped that in the near future the next generation of coupled earth system models that include both the natural system and the social dimension will be developed.
基金supported by the National Key Research&Development Plan of China(No.2016YFA0602703 and No.2016YFC1401603)the special fund forthe Second Institute of Oceanography(No.JG1620)+3 种基金the National Natural Science Foundation of China(No.41705048,No.41605036 and No.41621064)Zhejiang Provincial Natural Science Foundation of China(No.LR16D060001)Sino-German cooperation in ocean and polar researchthe national-level major cultivation project of Guangdong Province(No.2014GKXM058)
文摘The areas covered by 1.5 ℃ and 2.0 ℃ warming thresholds under RCP2.6, RCP4.5, and RCP8.5 were analyzed based on 22 CMIP5 models. More than 90% of the model runs are in agreement that by the end of the 21 st century, near-surface air temperature changes over ~5%(~2%), ~40%(~18%), and ~92%(~86%)of the globe will cross the 1.5 ℃(2.0 ℃) threshold under RCP2.6, RCP4.5, and RCP8.5, respectively. Under RCP8.5, nearly the whole of North America, Europe + Russia, Africa, and Asia–Russia will cross the 1.5 ℃(2.0 ℃) threshold in ~2050(~2060), while the coverage rates over South America and Oceania are ~80%(~75%) and ~50%(~30%), respectively. The threshold-onset time(TOT) for 2 ℃ warming is earliest over Europe + Russia and North America, followed by Africa, Asia–Russia, South America, and finally Oceania under the RCP4.5 and RCP8.5 scenarios. The TOT for 1.5 ℃ is ~10–30 years ahead of that for 2.0 ℃.
基金the National Key Research and Development Program of China(2018YFD0500100,2016YFD0500205)Discipline Development Grant from College of Animal Sciences FAFU(2018DK003)+3 种基金Natural Science Foundation of China(31602046)National Basic Research Program(973)of China(2015CB910502)Program for Fujian University Outstanding Youth Scientific Research,Science and Technology Innovation Special Foundation of Fujian Agriculture and Forestry University(KFA17229A)Collaborative Innovation Center of Animal Health and Food Safety Application Technology in Fujian,Fujian Vocational College of Agriculture(Kla17H01A).
文摘Beak and feather disease virus(BFDV) is an infectious agent responsible for feather degeneration and beak deformation in birds. In March 2017, an epidemic of psittacine beak and feather disease(PBFD) struck a farm in Fuzhou in the Fujian Province of southeast China, resulting in the death of 51 parrots. In this study, the disease was diagnosed and the pathogen was identified by PCR and whole genome sequencing. A distinct BFDV strain was identified and named as the FZ strain.This BFDV strain caused severe disease symptoms and pathological changes characteristic of typical PBFD in parrots, for example, loss of feathers and deformities of the beak and claws, and severe pathological changes in multiple organs of the infected birds. Phylogenetic analysis showed that the FZ strain was more closely related to the strain circulating in New Caledonia than the strains previously reported in China. Nucleotide homology between the FZ strain and other 43 strains of BFDV ranged from 80.0% to 92.0%. Blind passage experiment showed that this strain had limited replication capability in SPF Chicken Embryos and DF-1 Cells. Furthermore, the capsid(Cap) gene of this FZ strain was cloned into the p GEX-4 T-1 expression vector to prepare the polyclonal anti-Cap antibody. Western blotting analysis using the anti-Cap antibody further confirmed that the diseased parrots were infected with BFDV. In this study, a PBFD and its pathogen was identified for the first time in Fujian Province of China, suggesting that future surveillance of BFDV should be performed.
基金This research was supported by the National Key R&D Program of China No.2019YFB1404903.
文摘This paper proposes a secure,reliable and collaborative data-sharing system for China’s housing provident fund based on blockchain.Firstly,federal computingwas introduced to realize“available but invisible”sharing of data about housing provident fund,which reduces the data leakage risk and improves the data availability.Secondly,four data sharing modes were proposed to deal with different situations with different amount of data provider and data.Lastly,to realize individual data deep sharing on the premise of security,an enterprise and personal information query authorization mechanism was established to provide solutions to personal and institutional authorization.This system helps to realize both the internal and external data sharing of the housing provident fund system under the premise of security and privacy protection.This system improves the efficiency of housing provident fund issue,and fully taps the value of data comprehensively.