Missing interpolation model for wind power data based on the improved CEEMDAN method and generative adversarial interpolation network

Randomness and fluctuations in wind power output may cause changes in important parameters(e.g.,grid frequency and voltage),which in turn affect the stable operation of a power system.However,owing to external factors(such as weather),there are often various anomalies in wind power data,such as missing numerical values and unreasonable data.This significantly affects the accuracy of wind power generation predictions and operational decisions.Therefore,developing and applying reliable wind power interpolation methods is important for promoting the sustainable development of the wind power industry.In this study,the causes of abnormal data in wind power generation were first analyzed from a practical perspective.Second,an improved complete ensemble empirical mode decomposition with adaptive noise(ICEEMDAN)method with a generative adversarial interpolation network(GAIN)network was proposed to preprocess wind power generation and interpolate missing wind power generation sub-components.Finally,a complete wind power generation time series was reconstructed.Compared to traditional methods,the proposed ICEEMDAN-GAIN combination interpolation model has a higher interpolation accuracy and can effectively reduce the error impact caused by wind power generation sequence fluctuations.

Association of genotypes of rs671 within ALDH2 with risk for gastric cardia adenocarcinoma in the Chinese Han population in high-and low-incidence areas

Objective: This study aimed to determine if gastric cardia adenocarcinoma(GCA) risk was associated with the lys(A or *2) allele at the rs671(glu504lys) polymorphism within the aldehyde dehydrogenase 2(ALDH2) gene in a Chinese Han population. We also aimed to investigate ALDH2 genotypic distributions between subjects from high- and low-incidence areas for both GCA and esophageal squamous cell carcinoma(ESCC).Methods: We designed a case-control study including 2,686 patients with GCA and 3,675 control subjects from high- and lowincidence areas for both GCA and ESCC in China. Taq Man allele discrimination assay was used to genotype the rs671 polymorphism. χ~2 test and binary logistic regression analysis were used to estimate the odds ratios for the development of GCA,and multivariate ordinal logistic regression was used to analyze ALDH2 genotypic distributions among different groups.Results: Compared with ALDH2*1/*1 homozygotes, ALDH2*1/*2 and ALDH2*2/*2 carriers did not increase the risk for GCA in the Chinese Han population(P>0.05). Interestingly, the ratio of homozygous or heterozygous ALDH2 *2 carriers in highincidence areas for both GCA and ESCC was lower than that in low-incidence areas(P<0.001).Conclusions: Genotypes of rs671 at ALDH2 may not increase GCA susceptibility in Chinese Han populations. In addition, the ALDH2 genotypic distribution differs between Chinese Han populations from high- and low-incidence areas for both GCA and ESCC. Our findings may shed light on the possible genetic mechanism for the dramatic geographic differences of GCA occurrence in China.

Water promoted photocatalytic transfer hydrogenation of furfural to furfural alcohol over ultralow loading metal supported on TiO_(2)

Photocatalytic hydrogenation of furfural offers an ideal method for selective biomass upgrading into value-added chemicals or fuel additives under mild conditions. However, it is still challenging to control the product selectivity due to side reactions of functional groups and reactive radical intermediates.Herein, photocatalytic transfer hydrogenation of furfural was studied using the TiO_(2)-based photocatalysts with alcohols as both the solvent and hydrogen donor. Ultralow loading metal supported on TiO_(2),together with adding a small amount of water in the system, were demonstrated to greatly increase the selectivity of furfuryl alcohol product. Electron paramagnetic resonance(EPR), ultraviolet-visible spectroscopy(UV-Vis) and photoluminescence(PL) measurements gave evidence that ultralow loading Pt or Pd on TiO_(2)increase the oxygen vacancy concentration and the photogenerated charge separation efficiency, which accelerates the photocatalytic reduction of furfural. In situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS) and mechanistic studies confirmed that photogenerated holes and electrons are active species, with dissociatively adsorbed methanol being directly oxidized by holes,furfural hydrogenated by protons and electrons and H_(2)O modifying the intermediate diffusion which contributes to high selectivity of furfuryl alcohol. This work demonstrates a simple approach to design photocatalysts and tune product selectivity in biomass valorization.

N6-methyladenine-modified DNA was decreased in Alzheimer’s disease patients

BACKGROUND In recent years,the prevalence of Alzheimer’s disease(AD)has increased,which places a great burden on society and families and creates considerable challenges for medical services.N6-methyladenine(m6A)deoxyribonucleic acid(DNA)adenine methylation is a novel biomarker and is abundant in the brain,but less common in AD.We support to analyze the relationship between DNA m6A and cognition in patients with AD and normal controls(NCs)in China.AIM To analyze the relationship between the novel m6A DNA and cognition in patients with AD and NCs in China.METHODS A total of 179 AD patients(mean age 71.60±9.89 years;males:91;females:88)and 147 NCs(mean age 69.59±11.22 years;males:77;females:70)who were age-and sex-matched were included in our study.All subjects underwent neuropsychological scale assessment and magnetic resonance imaging examination.Apolipoprotein E(APOE)genotypes were measured through agarose gel electrophoresis.Global m6A levels were evaluated by a MethylFlash m6A DNA Methylation ELISA Kit(colorimetric).Global m6A levels in total DNA from ten AD patients with 18F-AV-45(florbetapir)positron emission tomography(PET)positivity and ten NCs with PET negativity were analyzed by dot blotting to determine the results.RESULTS Our ELISA results showed that the global m6A DNA levels in peripheral blood were different between patients with AD and NCs(P=0.002;<0.05).And ten AD patients who were PET positive and ten NCs who were PET negative also showed the same results through dot blotting.There were significant differences between the two groups,which indicated that the leukocyte m6A DNA levels were different(P=0.005;<0.05).The m6A level was approximately 8.33%lower in AD patients than in NCs(mean 0.011±0.006 vs 0.012±0.005).A significant correlation was found between the Montreal Cognitive Assessment score and the peripheral blood m6A level in the tested population(r=0.143,P=0.01;<0.05).However,no relationship was found with APOEε4(P=0.633,>0.05).Further studies should be performed to validate these findings.CONCLUSION Our results show that reduced global m6A DNA methylation levels are significantly lower in AD patients than in NCs by approximately 8.33%in China.

Synthesis and aggregation properties of amphiphilic mono and bisadducts of fullerene in aqueous solution

New amphiphilic[60]fullerene monoadduct TPF and bisadducts BTPF were synthesized and well-characterized. Their aggregation properties in aqueous solution was investigated by UV-vis and TEM methods. In aqueous solution, monoadduct TPF forms irregularly shaped and some rod-like aggregates, whereas bisadducts BTPF gives sphadcal aggregates with diameters of 50-150 rim. It indicated that the aggregation properties of amphiphilic fullerene derivatives depend on the number of hydrophilic